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  • MACHEREY-NAGEL GmbH & Co. KG Neumann-Neander-Str. 68 52355 Dren DeutschlandFrankreich:MACHEREY-NAGEL EURLTel.: +33 388 68 22 68Fax: +33 388 51 76 88E-Mail: [email protected]

    Schweiz:MACHEREY-NAGEL AGTel.: +41 62 388 55 00Fax: +41 62 388 55 05E-Mail: [email protected]

    Deutschlandund International:Tel.: +49 24 21 969-0Fax: +49 24 21 969-199E-Mail: [email protected]

    www.mn-net.com

    www.mn-net.comMACHEREY-NAGELEN ISO 9001: 2008

    ZERTIFIZIERT

    USA:MACHEREY-NAGEL Inc.Tel.: +1 484 821 0984Fax: +1 484 821 1272E-Mail: [email protected]

    . . . we Meet your Needs

    Columns and suppliescatalog

    HPLC GC TLC

    SPE and Flash Syringe filters

    Vials and caps

    MA

    CH

    EREY-N

    AG

    EL Chrom

    atography

  • [email protected]

    Chromatography

    How to contact us

    Meeting your needs in all questions concerning ChromatographyTechnical support and customer services Chromatography:

    Phone +49 24 21 969-175 or -370

    MACHEREY-NAGEL worldwide our products are globally available

    Our customers can count on competent and reliable service all over the world: BranchesinFrance,Switzerland,andtheUnitedStateswithscientificallyeducatedstaff Globallyoperatingnetworkofqualifiedandspeciallytraineddistributorsinmorethan150coun-tries

    For a complete list of branches and authorized distributors see www.mn-net.com/distributors.

    Germany and inter national USA

    MACHEREY-NAGEL GmbH & Co. KGNeumann-Neander-Str. 68 52355Dren

    MACHEREY-NAGEL Inc.2850EmrickBlvd. Bethlehem,PA18020

    phone +492421969-0 phone +14848210984toll-free 08002616000 toll-free 888-321-6224(MACH)fax +492421969-199oder-198 fax +14848211272e-mail [email protected] E-Mail [email protected]

    France Switzerland

    MACHEREY-NAGEL EURL1,rueGutenbergB.P.135 67722Hoerdt

    MACHEREY-NAGEL AGHirsackerstr.7Postfach255 4702Oensingen

    phone +33388682268 phone +41623885500fax +33388517688 fax +41623885505e-mail [email protected] e-mail [email protected]

  • www.mn-net.com

    Chromatography

    MACHEREY-NAGEL Company profile

    Since1911MACHEREY-NAGELhasrepresentedhighquality,innovationandreliabilityinchemicalandbio molecular analysis. Friendly expert advice for our highly valued customers as well as outstanding product qualityhavebeenthecornerstonesofourcorporatesuccessformorethan100years.CEOC.Wagner,thegreat-granddaughterofthecompanysfounder,hasbeenmanagingtheenterprisesince2000.Our product ranges:

    Filtration Rapid Tests Water Analysis Chromatography Bioanalysis

    Dedicated from the very first: Milestones of Chromatography at MACHEREY-NAGEL

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    160 278 328 370

    20 30 40 min

    C

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    1952: MNlaunchesthefirstproducts for paper chromatography. In the sameyear,MartinandSynge receive the Nobel Prize in Chemistry for the development of partition chromatography.

    NUCLEODUR NUCLEOSHELL

    1961: MACHEREY-NAGELbecomes one of the pioneersinTLC.

    1970: Expansionoftheproduct range by column chromatography

    1974: NUCLEOSILoneofthefirstsphericalHPLCsilicasleadstoour core competence in silica technology

    1994: OPTIMA capillary columns for optimum GC separations

    1987: CHROMABOND columnsforSPE

    2002: NUCLEODUR

    high purity spherical

    silica forHPLC

    2011: NUCLEOSHELL core shell silica for highest efficiencyinHPLC

    1982: firstfusedsilicacapillarycolumns for GC

  • [email protected]

    Chromatography

    MACHEREY-NAGEL on the internet

    Visit our Chromatography pages

    www.mn-net.com

    Productinformationalwaysup-to-date ChromaNews Jobopportunities Materialsafetydatasheets Free application database with about 3000 chromatography applications

  • www.mn-net.com

    Chromatography

    Catalog contents

    Solid Phase Extraction and Flash chromatographyCHROMABONDphasesandaccessoriesforSPE 152High-throughputSPEandFlashchromatography 5364

    Sample clarificationCHROMAFILsyringefilters 6676

    Vials and closuresVials and closures 77103Autosampler compatibility 103108

    Liquid chromatographyColumnsforHPLC 110197Packings for liquid chromatography 198206

    Thin layer chromatographyPlates,kitsandadsorbentsforTLC 208234

    Gas chromatographyCapillary columns for GC 236281ReagentsforGC 282291Accessories for GC 293297

    AppendicesProduct and subject index, index of reference numbers, trademarks, USP lists

    298327

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    Sample preparation

    New products for sample preparation

    CHROMABOND HR-Xpert your way to cleaner samples by SPEThe professional concept of innovative RP and mixed-mode ion exchange phases for SPE

    CHROMABOND HR-XhydrophobicPS/DVBcopolymer CHROMABOND HR-XC and HR-XCW strong and weak mixed-mode cation exchangers

    CHROMABOND HR-XA and HR-XAW strong and weak mixed-mode anion exchangers

    Now available in 2 particle sizes: standardparticlesize85m particlesize45m for smaller sample volumes, lower adsorbent weight and smaller elution volumes

    Order your free samples today! [email protected]

    Page

    10

    New CHROMAFIL filters for optimum filtration results CHROMAFIL Combi filters Syringefilterswithacoarseglassfiberprefilter recommended for solution with a high particle load NewdimensionsandporesizesforNylon,celluloseacetateandPTFEfilters

    Page 68

    Vials and closures completely revised product range Largeselectionof Crimp neck vials, crimp closures, crimping tools Screw neck vials and screw closures Special vials and closures Highqualityproductsatanequitable Pag

    e

    77

    price performance ration

    Welookforwardtosharingourexpertisewithyou: [email protected]

  • www.mn-net.com

    HPLC

    New products for HPLC

    NUCLEOSHELL core-shell silica for rapid, efficient HPLC Solid core of silicon dioxide, homogeneous shell of porous silica Highestefficiencycomparedtototallyporousmaterials Poresize90;particlesize2.7m(core1.7m); specificsurface130m2/g Lowerbackpressureenablesuseon conventionalLCsystems

    Page 144 Pressurestability600bar

    NUCLEOSHELL RP 18 nonpolar high density phase Key features: Suitable for LC/MSandHPLCatpHextremes(pH111) Superior base deactivation, ideal for method development

    Recommended application: Overall sophisticated analytical separations, e.g.,analgesics,anti-inflammatorydrugs,antidepressants; herbicides;phytopharmaceuticals;immunosuppressants

    Page 148

    USP L1

    O

    NH3C

    CH3Si(CH3)3

    NUCLEOSHELL PFP hydrophobic pentafluorophenyl phase Key features: Hydrophobicphasewithalternativeselectivityincomparisonto

    classical C18modifications Separationprinciplebasedon4retentionmechanisms(polarin-teractions(Hbonds),dipole-dipoleinteractions,-interactions,hydrophobicinteractions)

    Recommended application: Aromatic and unsaturated compounds, phenols, halogenated com-pounds,isomers,polarcompoundslikepharmaceuticals,antibiotics;high retention of basic compounds

    USP L43

    F

    F

    F

    F

    F

    O

    H

    O

    Page

    150

    NUCLEOSHELL HILIC zwitterionic phase

    NPC IC

    HILIC

    RPC

    Eluent

    AnalytSorb

    ens

    Key features: Ideal for reproducible and stable

    chromatography of highly polar analytes Very short column equilibration times

    Page 152

    Recommended application: Hydrophiliccompoundssuchasorganicpolaracidsandbases,polarnatural compounds, nucleosides, oligonucleotides, amino acids, peptides, water soluble vitamins

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    New products for HPLC

    NUCLEODUR PolarTec RP phase with embedded polar group Key features: Excellentbasedeactivation Suitable for LC/MSandstablein100%aqueousmobilephases Pronounced steric selectivity

    Recommended application: Exceptionalselectivityforphenolsandnitrogencontainingcom-pounds, polar compounds like basic pharmaceuticals, organic acids, pesticides, amino acids, water soluble vitamins, etc.

    USP L1 and L60

    Page

    124

    NUCLEODUR PFP hydrophobic pentafluorophenyl phase Key features: Hydrophobicphasewithalternativeselectivityincomparisonto

    classical C18modifications Separationprinciplebasedon4retentionmechanisms(polarinteractions(Hbonds),dipole-dipoleinteractions,-interac-tions,hydrophobicinteractions)

    Suitable for LC/MS due to low bleeding characteristics Recommended application: Aromatic and unsaturated compounds, phenols, halogenated com-pounds, isomers, polar compounds like pharmaceuticals, antibiot-ics;highretentionofbasiccompounds

    USP L43 Page 136

    HPLC

  • www.mn-net.com

    Chromatography

    New products for TLC and GC

    ALUGRAM Xtra optimized TLC silica layers on aluminium Outstanding wettability for precise colorization results, evenwith100%aqueousderivatizationandvisualizationreagents

    Excellent separation efficiency and reproducibility from lot to lot Easy and reliable cuttingduetoanoptimizedbindersystem,noflakingofsilica;nowavailableas ALUGRAM Xtra SIL Gwithunmodifiedstandardsilica ALUGRAM Xtra Nano-SILwithunmodifiedHPTLCsilica ALUGRAM Xtra SILGUR standard silica with concentrating zone ALUGRAM Xtra Nano-SILGURHPTLCwithconcentratingzone

    Pages 214218

    OPTIMA WAXplus OPTIMA FFAPplus optimized polar phases for GC WAXplus Polar phase with improved cross-linking for reduced col-umn bleeding and better tem-perature stability

    H

    H

    O C

    n

    OHH

    H

    H

    C

    Good solvent stability, extended column life-time,betterperformanceintheMSincom-parisontoconventionalWaxphases Recommendedapplication: broad