www.leica-microsystems.com

LEIC

A M

ICR

OS

YSTE

MS

LIFE

SC

IEN

CE

RES

EA

RC

H Leica DMi8开放的平台 个性化定制

新一代研究型倒置显微镜

新理念 新视角 新发现

Leica Microsystems GmbH · Ernst-Leitz-Strasse 17–37 · D-35578 WetzlarT +49 64 41 29-40 00 · F +49 64 41 29-41 55 · www.leica-microsystems.com

www.leica-microsystems.com

The statement by Ernst Leitz in 1907,

“With the user, for the user,” describes

the fruitful collaboration with end users

and driving force of innovation at Leica

Microsystems. We have developed five

brand values to live up to this tradition:

Pioneering, High-end Quality, Team Spirit,

Dedication to Science, and Continuous

Improvement. For us, living up to these

values means: Living up to Life.

LIFE SCIENCE DIVISION

The Leica Microsystems Life Science

Division supports the imaging needs of

the scientific community with advanced

innovation and technical expertise for the

visualization, measurement, and analysis

of microstructures. Our strong focus on

understanding scientific applications puts

Leica Microsystems’ customers at the

leading edge of science.

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281 mm

310 mm542 mm

500 mm

670 mm

徕卡显微系统的全球运作分为三个部门，

已进入各地市场领导者行列：

LIFE SCIENCE DIVISION

徕卡公司生命科学部门为科研用户提供最

先进的显微成像技术。实现显微结构的观

察、测量和分析。理解并满足用户的科研

应用是我们在市场中领先的关键。

INDUSTRY DIVISION

徕卡公司工业部门的工作核心工作是支持

客户寻求高质量的最终结果。徕卡公司提

供了最好、最新颖的成像系统，满足他们在

日常工作以及在工业研究应用中的观察、

测量和分析微观结构的需要，满足材料科

学和质量控制、法医学科学调查和教育应

用的需要。

MEDICAL DIVISION

徕卡公司医疗显微镜部门的工作重点是与

手术外科合作，以无论是现在还是将来都

是最优秀、最新颖的手术显微技术为他们

提供支持，更好地为患者服务。

Ernst Leitz 于 1907 年发表了“与用户合作，

使用户受益”的声明，描述了徕卡显微系

统与最终用户的通力协作以及不断创新的

驱动力。我们已经开发了五个品牌价值来

实 现 这一 传 统：P i o n e e r i n g、H i g h - e n d

Quality、Team Spirit、Dedication to Science 和

Continuous Improvement。对我们来说，实现

这些价值就意味着： Living up to Life。

徕卡显微系统（上海）贸易有限公司北京分公司

地址：北京市首都体育馆南路6号新世纪办公楼858室

电话：010-68492698

传真：010-68492965

徕卡显微系统（上海）贸易有限公司

地址：上海市徐家汇路610号日月光中心广场17楼

电话：021-60396000

传真：021-63876698

徕卡显微系统（上海）贸易有限公司成都分公司

地址：成都市锦江区创意产业商务区三色路38号博瑞.创意成都B座1601室

电话：028-85272215

传真：028-85288856

徕卡显微系统（上海）贸易有限公司广州分公司

地址：广州市先烈中路69号东山广场2615-2617室

电话：020-87320225

传真：020-87321519

徕卡显微系统（上海）贸易有限公司西安分公司

地址：西安室雁塔区南二环西段64号凯德广场写字楼8楼09室

电话：029-85413851

传真：029-85413142

徕卡仪器有限公司

地址：香港北角電氣道148號37樓3705室

电话：(852) 25646699

传真：(852) 25644163

徕卡显微系统（上海）贸易有限公司沈阳分公司

地址：沈阳市河区惠工街 10 号卓越大厦 9层 01 室

电话：024-31958890

传真：024-31958895

研究人员深知视角的变换常常会带来最令人兴奋的发现，我们也是如

此。Leica DMi8 是倒置显微镜的革新。它采用开放的平台，个性化定制。

Leica DMi8 给您的工作带来灵感，满足您探索生命奥秘的需求。

Leica DMi8， 一个满足生命科学未来发展的平台

从基本应用到高端成像 - Leica DMi8显微镜的配置与您不断变化的需求一同

成长。

光学扩展模块， 无限远光路接口灵活扩展您的应用

从观察到介入 - Leica DMi8 开创研究的全新空间。

全面的活细胞实验解决方案

从简单观察到复杂分析 - Leica DMi8 和 LAS X 软件完美结合，用于研究活体

标本。

“生命科学是不断向前发展的。在徕卡显微系统，我们已经搭建了一个专用平台，满足研究人

员的不同需求。Leica DMi8量身打造的解决方案，完全超越了过去固定的显微镜配置。”

徕卡显微系统首席科学技术官

Julian Burke 博士

Leica DMi8研究型倒置显微镜平台

享受配置自由 - 迎接未来挑战No matter what type of samples you work with, no matter where your research is headed – Leica DMi8 will be there to assist you: ready to grow, ready to change, ready for brilliant results.

FANTASTIC OPTICAL QUALITY

OPTIMIZED FOR SCMOS CAMERAS

Do you want to see more of your sample with

the highest possible resolution? We enlarged

the field of view (FOV) for all camera ports.

Optimized for state-of-the-art sCMOS came-

ras, the Leica DMi8 has 19 mm FOV. The full

range of contrast techniques is available:

from Brightfield, Integrated Modulation

Contrast, and Phase Contrast to Darkfield,

Differential Interference Contrast (DIC),

and Fluorescence. With the highest quality

imaging options, see your sample at its best.

MICRO-MANIPULATION SOLUTIONS

Extend your capabilities. The Leica DMi8

works with systems from Eppendorf,

Narishige, Leica Microsystems, and others.

INTUITIVE OPERATION

The Leica DMi8 and LAS X are designed

to support you. All interfaces are easy

to navigate, giving you better results in a

shorter time than ever before.

EASY ON YOUR BUDGET –

EASILY UPGRADEABLE

The Leica DMi8 takes you beyond configu-

ration restrictions. With the freedom of a

completely modular system, you can create

the perfect system for your research. For

3D images, you can integrate a motorized

focus into a manual system. Or if you want

multi-color images, start with a motorized

filter wheel and manual focus. With hun-

dreds of possible combinations, you can

create the best solution for your work.

“My equipment needs to grow with the increasing number of demanding applications – just like the Leica Microsystems imaging solution.”

Prof. Dr. Ralf Jacob University of Marburg, Germany

Comparison of 19 mm FOV with standard 16 mm camera ports (dotted line). Courtesy of IGBMC, Strasbourg, France

Blastocyst injection. Courtesy of IGBMC, Strasbourg, France

Leica LAS X software, Easy Operation Mode

The whole story of Leica DMi8

“我的设备需要与日益增加的苛

刻应用共同成长 - 正如徕卡显微

系统成像解决方案那样。”

德国马尔堡大学

Ralf Jacob教授/博士

No matter what type of samples you work with, no matter where your research is headed – Leica DMi8 will be there to assist you: ready to grow, ready to change, ready for brilliant results.

FANTASTIC OPTICAL QUALITY

OPTIMIZED FOR SCMOS CAMERAS

Do you want to see more of your sample with

the highest possible resolution? We enlarged

the field of view (FOV) for all camera ports.

Optimized for state-of-the-art sCMOS came-

ras, the Leica DMi8 has 19 mm FOV. The full

range of contrast techniques is available:

from Brightfield, Integrated Modulation

Contrast, and Phase Contrast to Darkfield,

Differential Interference Contrast (DIC),

and Fluorescence. With the highest quality

imaging options, see your sample at its best.

MICRO-MANIPULATION SOLUTIONS

Extend your capabilities. The Leica DMi8

works with systems from Eppendorf,

Narishige, Leica Microsystems, and others.

INTUITIVE OPERATION

The Leica DMi8 and LAS X are designed

to support you. All interfaces are easy

to navigate, giving you better results in a

shorter time than ever before.

EASY ON YOUR BUDGET –

EASILY UPGRADEABLE

The Leica DMi8 takes you beyond configu-

ration restrictions. With the freedom of a

completely modular system, you can create

the perfect system for your research. For

3D images, you can integrate a motorized

focus into a manual system. Or if you want

multi-color images, start with a motorized

filter wheel and manual focus. With hun-

dreds of possible combinations, you can

create the best solution for your work.

“My equipment needs to grow with the increasing number of demanding applications – just like the Leica Microsystems imaging solution.”

Prof. Dr. Ralf Jacob University of Marburg, Germany

Comparison of 19 mm FOV with standard 16 mm camera ports (dotted line). Courtesy of IGBMC, Strasbourg, France

Blastocyst injection. Courtesy of IGBMC, Strasbourg, France

Leica LAS X software, Easy Operation Mode

The whole story of Leica DMi8

No matter what type of samples you work with, no matter where your research is headed – Leica DMi8 will be there to assist you: ready to grow, ready to change, ready for brilliant results.

FANTASTIC OPTICAL QUALITY

OPTIMIZED FOR SCMOS CAMERAS

Do you want to see more of your sample with

the highest possible resolution? We enlarged

the field of view (FOV) for all camera ports.

Optimized for state-of-the-art sCMOS came-

ras, the Leica DMi8 has 19 mm FOV. The full

range of contrast techniques is available:

from Brightfield, Integrated Modulation

Contrast, and Phase Contrast to Darkfield,

Differential Interference Contrast (DIC),

and Fluorescence. With the highest quality

imaging options, see your sample at its best.

MICRO-MANIPULATION SOLUTIONS

Extend your capabilities. The Leica DMi8

works with systems from Eppendorf,

Narishige, Leica Microsystems, and others.

INTUITIVE OPERATION

The Leica DMi8 and LAS X are designed

to support you. All interfaces are easy

to navigate, giving you better results in a

shorter time than ever before.

EASY ON YOUR BUDGET –

EASILY UPGRADEABLE

The Leica DMi8 takes you beyond configu-

ration restrictions. With the freedom of a

completely modular system, you can create

the perfect system for your research. For

3D images, you can integrate a motorized

focus into a manual system. Or if you want

multi-color images, start with a motorized

filter wheel and manual focus. With hun-

dreds of possible combinations, you can

create the best solution for your work.

“My equipment needs to grow with the increasing number of demanding applications – just like the Leica Microsystems imaging solution.”

Prof. Dr. Ralf Jacob University of Marburg, Germany

Comparison of 19 mm FOV with standard 16 mm camera ports (dotted line). Courtesy of IGBMC, Strasbourg, France

Blastocyst injection. Courtesy of IGBMC, Strasbourg, France

Leica LAS X software, Easy Operation Mode

The whole story of Leica DMi8

No matter what type of samples you work with, no matter where your research is headed – Leica DMi8 will be there to assist you: ready to grow, ready to change, ready for brilliant results.

FANTASTIC OPTICAL QUALITY

OPTIMIZED FOR SCMOS CAMERAS

Do you want to see more of your sample with

the highest possible resolution? We enlarged

the field of view (FOV) for all camera ports.

Optimized for state-of-the-art sCMOS came-

ras, the Leica DMi8 has 19 mm FOV. The full

range of contrast techniques is available:

from Brightfield, Integrated Modulation

Contrast, and Phase Contrast to Darkfield,

Differential Interference Contrast (DIC),

and Fluorescence. With the highest quality

imaging options, see your sample at its best.

MICRO-MANIPULATION SOLUTIONS

Extend your capabilities. The Leica DMi8

works with systems from Eppendorf,

Narishige, Leica Microsystems, and others.

INTUITIVE OPERATION

The Leica DMi8 and LAS X are designed

to support you. All interfaces are easy

to navigate, giving you better results in a

shorter time than ever before.

EASY ON YOUR BUDGET –

EASILY UPGRADEABLE

The Leica DMi8 takes you beyond configu-

ration restrictions. With the freedom of a

completely modular system, you can create

the perfect system for your research. For

3D images, you can integrate a motorized

focus into a manual system. Or if you want

multi-color images, start with a motorized

filter wheel and manual focus. With hun-

dreds of possible combinations, you can

create the best solution for your work.

“My equipment needs to grow with the increasing number of demanding applications – just like the Leica Microsystems imaging solution.”

Prof. Dr. Ralf Jacob University of Marburg, Germany

Comparison of 19 mm FOV with standard 16 mm camera ports (dotted line). Courtesy of IGBMC, Strasbourg, France

Blastocyst injection. Courtesy of IGBMC, Strasbourg, France

Leica LAS X software, Easy Operation Mode

The whole story of Leica DMi8

绝佳的光学品质

sCMOS 相机的最优选择

徕卡显微系统因其光学创新力而著名。

Leica DMi8 提供全方位的观察方法：从明

场、相差，集成调制对比（IMC），到暗场、

微分干涉（DIC）以及荧光。Leica DMi8 为

了搭配使用最先进的 sCMOS 相机， 将照

相视野扩展至 19mm。

直观化操作

Leica DMi8和 LAS X 组成的系统为满足您

的工作而设计。操作界面可轻松掌握，

使您在比以往更短的时间内获得更佳的

结果。

按预算灵活配置

- 轻松升级

使用 Leica DMi8，您只需要按需购买。如

果您的工作集中在记录存档方面，并且

延伸聚焦、自动对焦或3D成像技术会对

您的工作带来帮助，那么您可以将电动

调焦驱动整合在纯手动系统上来达到目

的。Leica DMi8 的开放式平台打破了固定

配置显微镜模型的限制，可以根据您的

需求改变，轻松升级。

显微操作的解决方案

您可以完全自由选择Eppendorf、Narishige、

徕卡显微系统及其他公司的产品。

无论您研究哪种类型的样品，无论您的研究方向是什么，

Leica DMi8 都将协助您：随时成长、随时改变，

以期取得杰出的成果。

Leica DMi8 的全部信息

使用Leica DMi8的19mm 照相视野观察的两细胞期，

虚线表示16mm 照相视野显示。

由法国斯特拉斯堡IGBMC提供

囊胚注射

由法国斯特拉斯堡IGBMC提供

Leica LAS X 软件，简易操作模式

探索生命的奥秘 - 讲述细胞的故事

新型LEICA DMi8调焦驱动

器官和生物体等大型样品的生命科学研

究，需要很长的调焦行程以及在这些行

程内的绝对精度。Leica DMi8 提供新型

闭环调焦驱动，配有世界领先的20nm闭

环重复精度以及12mm超长调焦行程，以

适应不同器皿，不同条件的活体成像。

为完整的三维图像重构提供了最高的精

准度。

超高速成像

为了理解活细胞的动态过程，必须将光

毒性以及光漂白降至最低。多维数据必

须在活体速度下捕捉。

Leica DMi8 sequencer 可以在微秒级别速

度和精度下同时控制所有过程。集成微

秒快速 LED 光源，例如 Lumen Dynamics

X-LED 或 Lumencor SpectraX， 以及来自

Andor 、 PCO 、Hamamatsu 等公司的先进

sCMOS相机，获得无与伦比的成像品质。

如果最快的切换仍然不够理想， 那么可

以利用LAS X 和Dual-View 图像分割器，同

时获取多通道图像。

创新型无限远光路接口

两条无穷远光路汇聚到显微镜中，可以

集成附加的外部光源和激光系统，实现

FRAP，光切换，光消融，光遗传等高端应

用更加方便，可行。无限远光路接口的特

殊设计提供了顶级的光学品质和灵活性。

钙离子成像

Leica DMi8 提供 FURA2 专用系统，配有

21ms 快速外部滤光转轮，以及具有最大

数值孔径和紫外透射率的新型物镜。

新型Fura物镜 数值孔径 340nm的透射率

（%）

PL FLUOTAR（340） 20x油镜 0.8 约50

PL FLUOTAR（340） 40x油镜 1.3 约40

PL FLUOTAR（340） 100x油镜 1.3 约60

Leica DMi8 全新的核心元件 - 无限远光路接口，是动态科学研究

时的最佳解决方案。它使显微镜可以附加众多功能，帮助您实

现对样品及其功能的互动研究 - 满足生命科学研究的未来趋势。

Leica DMi8 的应用信息

12mm超长调焦行程，超精准定位无限远光路扩展（红色表示）

由日本东京大学

Kazunori Kanemaru和Masamitsu Iino 博士提供

The Leica DMi8’s new core element, the Infinity Port, is the answer to the dynamic nature of science. It provides access to a wide range of functions for direct interaction with your sample – meeting the trends in life sciences.

Courtesy of Drs. Kazunori Kanemaru and Masamitsu Iino, The University of Tokyo, Japan

THE INNOVATIVE INFINITY PORT

Open to even more possibilities, the Leica

DMi8 features an additional incident illu-

mination port. The Infinity Port provides

unmatched flexibility along with the highest

optical performance.

This novel design facilitates the integration

of additional fluorescence light sources and

laser systems for advanced applications

like FRAP, photo-switching, ablation, opto-

genetics, tweezing, and many more.

NEW LEICA DMi8 FOCUS DRIVE

The Leica DMi8 features a new Closed

Loop Focus with 20 nm positional accu-

racy. Combined with an increased travel

range of 12 mm, the Leica DMi8 offers

high precision 3D image reconstruction

of large tissues and complete organisms.

Get high quality data with unprecedented

accuracy with this innovation.

CALCIUM IMAGING

The Leica DMi8 offers a dedicated system

for FURA2 imaging. New objectives com-

bine high NA and UV trans mission of up to

60 % at 340 nm. Along with extremely fast

external filter wheels (24 ms switching

time) the system is perfectly equipped

for capturing fast dynamic processes like

calcium measurements.

ULTIMATE HIGH-SPEED IMAGING

To understand dynamic processes in

live cells, multidimensional data must be

captured at the speed of life.

Control all processes simultaneously with the

Leica DMi8 sequencer. Integrate light sour-

ces and state-of-the-art sCMOS cameras with

µs speed and accuracy. Add light sources

like the Lumen Dynamics X-LED or Lumencor

SpectraX and cameras from Andor, PCO, Hama-

matsu, and others for unmatched imaging

performance. For simultaneous multi-channel

image acquisition, use the Dual-View Image

Splitter. With so many possibilities find the

best solution for your high speed application,

all integrated in LAS X software.

The new Infinity Port (shown in red) 20 nm precision for a 12 mm travel range

Leica DMi8 applications

The Leica DMi8’s new core element, the Infinity Port, is the answer to the dynamic nature of science. It provides access to a wide range of functions for direct interaction with your sample – meeting the trends in life sciences.

Courtesy of Drs. Kazunori Kanemaru and Masamitsu Iino, The University of Tokyo, Japan

THE INNOVATIVE INFINITY PORT

Open to even more possibilities, the Leica

DMi8 features an additional incident illu-

mination port. The Infinity Port provides

unmatched flexibility along with the highest

optical performance.

This novel design facilitates the integration

of additional fluorescence light sources and

laser systems for advanced applications

like FRAP, photo-switching, ablation, opto-

genetics, tweezing, and many more.

NEW LEICA DMi8 FOCUS DRIVE

The Leica DMi8 features a new Closed

Loop Focus with 20 nm positional accu-

racy. Combined with an increased travel

range of 12 mm, the Leica DMi8 offers

high precision 3D image reconstruction

of large tissues and complete organisms.

Get high quality data with unprecedented

accuracy with this innovation.

CALCIUM IMAGING

The Leica DMi8 offers a dedicated system

for FURA2 imaging. New objectives com-

bine high NA and UV trans mission of up to

60 % at 340 nm. Along with extremely fast

external filter wheels (24 ms switching

time) the system is perfectly equipped

for capturing fast dynamic processes like

calcium measurements.

ULTIMATE HIGH-SPEED IMAGING

To understand dynamic processes in

live cells, multidimensional data must be

captured at the speed of life.

Control all processes simultaneously with the

Leica DMi8 sequencer. Integrate light sour-

ces and state-of-the-art sCMOS cameras with

µs speed and accuracy. Add light sources

like the Lumen Dynamics X-LED or Lumencor

SpectraX and cameras from Andor, PCO, Hama-

matsu, and others for unmatched imaging

performance. For simultaneous multi-channel

image acquisition, use the Dual-View Image

Splitter. With so many possibilities find the

best solution for your high speed application,

all integrated in LAS X software.

The new Infinity Port (shown in red) 20 nm precision for a 12 mm travel range

Leica DMi8 applications

The Leica DMi8’s new core element, the Infinity Port, is the answer to the dynamic nature of science. It provides access to a wide range of functions for direct interaction with your sample – meeting the trends in life sciences.

Courtesy of Drs. Kazunori Kanemaru and Masamitsu Iino, The University of Tokyo, Japan

THE INNOVATIVE INFINITY PORT

Open to even more possibilities, the Leica

DMi8 features an additional incident illu-

mination port. The Infinity Port provides

unmatched flexibility along with the highest

optical performance.

This novel design facilitates the integration

of additional fluorescence light sources and

laser systems for advanced applications

like FRAP, photo-switching, ablation, opto-

genetics, tweezing, and many more.

NEW LEICA DMi8 FOCUS DRIVE

The Leica DMi8 features a new Closed

Loop Focus with 20 nm positional accu-

racy. Combined with an increased travel

range of 12 mm, the Leica DMi8 offers

high precision 3D image reconstruction

of large tissues and complete organisms.

Get high quality data with unprecedented

accuracy with this innovation.

CALCIUM IMAGING

The Leica DMi8 offers a dedicated system

for FURA2 imaging. New objectives com-

bine high NA and UV trans mission of up to

60 % at 340 nm. Along with extremely fast

external filter wheels (24 ms switching

time) the system is perfectly equipped

for capturing fast dynamic processes like

calcium measurements.

ULTIMATE HIGH-SPEED IMAGING

To understand dynamic processes in

live cells, multidimensional data must be

captured at the speed of life.

Control all processes simultaneously with the

Leica DMi8 sequencer. Integrate light sour-

ces and state-of-the-art sCMOS cameras with

µs speed and accuracy. Add light sources

like the Lumen Dynamics X-LED or Lumencor

SpectraX and cameras from Andor, PCO, Hama-

matsu, and others for unmatched imaging

performance. For simultaneous multi-channel

image acquisition, use the Dual-View Image

Splitter. With so many possibilities find the

best solution for your high speed application,

all integrated in LAS X software.

The new Infinity Port (shown in red) 20 nm precision for a 12 mm travel range

Leica DMi8 applications

创建最适合您的活细胞环境 - 完美捕捉将要发生的信息

“徕卡的产品能够完美的相互契

合，并被灵活的配置以满足不同

研究的需要。”

法国斯特拉斯堡IGBMC

Jean-Luc Vonesch 博士

无需再次对焦

利用Leica LAS X软件自动对焦以及闭环

调焦系统，可实现最精确的调焦重复性。

一键点击，徕卡AFC控制即可永久精确地

保持焦平面。即使在强烈的温度变化，

或长距离载物台移动时，您的焦平面也

始终保持稳定。徕卡AFC是基于对培养

皿或多孔板底部的LED光束的反射信号

探测。光反射到传感器，实时校正对焦。

舒适的环境

在活细胞实验中， 保持细胞生长的舒适

是最具挑战性的重要任务。使用Leica DMi8

所有的环境参数都可通过 LAS X 软件控

制，并且链接到图像采集。“达到适合的

环境条件时，自动启动实验”是 DMi8 活

细胞系统的独特性能， 避免产生假象。

直观化、多功能软件

新型的LAS X软件将目前显微镜软件中最

强大的功能集成在一个软件平台，同时

关注界面、功能以及工作流程的实用性。

• 专业的采集和硬件配置

• 多维数据组分析

• 高级环境控制功能

Leica DMi8 通过无缝集成环境控制系统，可轻松控制活细胞实

验的参数，获取高度可重复的数据， 使得更深刻地洞察生命奥

秘。

鸡胚背根神经节神经元（绿色：肌动蛋白，YFP）。

由日本东北大学 Kazumasa Ohashi 提供

通过徕卡显微系统的移动连接，随时随地监控实验

Leica DMi8：超高分辨显微系统（如GSD 3D 和 STED 3X）的

下一代显微镜平台

由德国马尔堡的 R. Jacob 和S. Bänfer 提供

NEVER FOCUS AGAIN

Save time searching for your cells and

eliminate photo-toxicity from fluorescent

light during focusing. Strong temperature

shifts, long distance stage movements:

your image remains constant.

One click of a button and the LED light

beam assisted Leica Adaptive Focus

Control (AFC) automatically maintains

your focus, in real time.

PLEASANT ENVIRONMENT

Keeping cells happy is the most challenging

and important task in live cell experiments.

With Leica DMi8, all environmental para-

meters are controlled via LAS X and are

linked to the image acquisition. Unique

features, such as ”start experiment when

the right environmental conditions are rea-

ched,“ eliminate the occurrence of artifacts.

Monitor your experiment anywhere at any time with Mobile Connection from Leica Microsystems

The Leica DMi8’s infinite capacity for seamless integration makes it easy to control the parameters of your live cell experiments. Obtain highly reproducible data to gain deeper insight into life.

Chick DRG neuron (green: Actin, YFP). Courtesy of Kazumasa Ohashi, Tohoku University, Japan

Focus Position

Detection Sensorwith Light Spot

Immersion Medium

Culture Medium

Cover Glass

Objective

Leica DMi8: platform for leading super resolution systems like GSD 3D and STED 3D. Courtesy of S. Hell, Max-Planck-Institut for Biophysical Chemistry, Göttingen, Germany

INTUITIVE AND VERSATILE SOFTWARE

The new LAS X combines the most

powerful microscope software features

available today in one package, yet

maintains usability in all aspects of the

interface, functions and workflow.

• Dedicated acquisition and hardware

implementation

• Analysis of multi-dimensional data sets

• Advanced environmental control

NEVER FOCUS AGAIN

Save time searching for your cells and

eliminate photo-toxicity from fluorescent

light during focusing. Strong temperature

shifts, long distance stage movements:

your image remains constant.

One click of a button and the LED light

beam assisted Leica Adaptive Focus

Control (AFC) automatically maintains

your focus, in real time.

PLEASANT ENVIRONMENT

Keeping cells happy is the most challenging

and important task in live cell experiments.

With Leica DMi8, all environmental para-

meters are controlled via LAS X and are

linked to the image acquisition. Unique

features, such as ”start experiment when

the right environmental conditions are rea-

ched,“ eliminate the occurrence of artifacts.

Monitor your experiment anywhere at any time with Mobile Connection from Leica Microsystems

The Leica DMi8’s infinite capacity for seamless integration makes it easy to control the parameters of your live cell experiments. Obtain highly reproducible data to gain deeper insight into life.

Chick DRG neuron (green: Actin, YFP). Courtesy of Kazumasa Ohashi, Tohoku University, Japan

Focus Position

Detection Sensorwith Light Spot

Immersion Medium

Culture Medium

Cover Glass

Objective

Leica DMi8: platform for leading super resolution systems like GSD 3D and STED 3D. Courtesy of S. Hell, Max-Planck-Institut for Biophysical Chemistry, Göttingen, Germany

INTUITIVE AND VERSATILE SOFTWARE

The new LAS X combines the most

powerful microscope software features

available today in one package, yet

maintains usability in all aspects of the

interface, functions and workflow.

• Dedicated acquisition and hardware

implementation

• Analysis of multi-dimensional data sets

• Advanced environmental control

NEVER FOCUS AGAIN

Save time searching for your cells and

eliminate photo-toxicity from fluorescent

light during focusing. Strong temperature

shifts, long distance stage movements:

your image remains constant.

One click of a button and the LED light

beam assisted Leica Adaptive Focus

Control (AFC) automatically maintains

your focus, in real time.

PLEASANT ENVIRONMENT

Keeping cells happy is the most challenging

and important task in live cell experiments.

With Leica DMi8, all environmental para-

meters are controlled via LAS X and are

linked to the image acquisition. Unique

features, such as ”start experiment when

the right environmental conditions are rea-

ched,“ eliminate the occurrence of artifacts.

Monitor your experiment anywhere at any time with Mobile Connection from Leica Microsystems

The Leica DMi8’s infinite capacity for seamless integration makes it easy to control the parameters of your live cell experiments. Obtain highly reproducible data to gain deeper insight into life.

Chick DRG neuron (green: Actin, YFP). Courtesy of Kazumasa Ohashi, Tohoku University, Japan

Focus Position

Detection Sensorwith Light Spot

Immersion Medium

Culture Medium

Cover Glass

Objective

Leica DMi8: platform for leading super resolution systems like GSD 3D and STED 3D. Courtesy of S. Hell, Max-Planck-Institut for Biophysical Chemistry, Göttingen, Germany

INTUITIVE AND VERSATILE SOFTWARE

The new LAS X combines the most

powerful microscope software features

available today in one package, yet

maintains usability in all aspects of the

interface, functions and workflow.

• Dedicated acquisition and hardware

implementation

• Analysis of multi-dimensional data sets

• Advanced environmental control NEVER FOCUS AGAIN

Save time searching for your cells and

eliminate photo-toxicity from fluorescent

light during focusing. Strong temperature

shifts, long distance stage movements:

your image remains constant.

One click of a button and the LED light

beam assisted Leica Adaptive Focus

Control (AFC) automatically maintains

your focus, in real time.

PLEASANT ENVIRONMENT

Keeping cells happy is the most challenging

and important task in live cell experiments.

With Leica DMi8, all environmental para-

meters are controlled via LAS X and are

linked to the image acquisition. Unique

features, such as ”start experiment when

the right environmental conditions are rea-

ched,“ eliminate the occurrence of artifacts.

Monitor your experiment anywhere at any time with Mobile Connection from Leica Microsystems

The Leica DMi8’s infinite capacity for seamless integration makes it easy to control the parameters of your live cell experiments. Obtain highly reproducible data to gain deeper insight into life.

Chick DRG neuron (green: Actin, YFP). Courtesy of Kazumasa Ohashi, Tohoku University, Japan

Focus Position

Detection Sensorwith Light Spot

Immersion Medium

Culture Medium

Cover Glass

Objective

Leica DMi8: platform for leading super resolution systems like GSD 3D and STED 3D. Courtesy of S. Hell, Max-Planck-Institut for Biophysical Chemistry, Göttingen, Germany

INTUITIVE AND VERSATILE SOFTWARE

The new LAS X combines the most

powerful microscope software features

available today in one package, yet

maintains usability in all aspects of the

interface, functions and workflow.

• Dedicated acquisition and hardware

implementation

• Analysis of multi-dimensional data sets

• Advanced environmental control

开放式显微镜平台 - 满足您的科研需要

“能有像徕卡这样的伙伴一起

突破壁垒真是太棒了。”

德国哥廷根

马克斯普朗克生物物理化学研究所

Stefan Hell教授

DMi8， 徕卡显微系统的骄傲

Leica DMi8 的设计和制造，传承了徕卡显

微系统产品优良的品质。精良的光学元

件、高品质的材料、耐用的设计、方便的

操作，无微不至、以客户为本的服务，传

递着无与伦比的性能以及用户至上的价

值观。

为您的研究敞开大门

Leica DMi8不但无缝整合了徕卡新款LAS

X软件，而且百分之百兼容Metamorph 软

件（Molecular Devices），确保您有理想的

应用软件配合使用。

徕卡显微系统邀请您参与、改进甚至创

建专属于您的 Leica DMi8 。这是一台可以

自由配置显微镜，拥有开放式的设计理

念，光学扩展模块含有两个新型无限远

接口，四个相机接口以及激光防护工具。

使用无限远接口可以将例如Linos 或 Thor-

labs等相关设备直接连接到您的Leica DMi8

上。

为您的科研提供最大程度的灵活性、功能性以及创新性,

徕卡显微系统与业界领先的多家公司合作。

Leica DMi 8, 最开放的显微镜平台。

Leica DMi8 的硬件部件

无限远光路接口

作为高性能解决方案的供应商，Andor凭借其特有的开

放式端口理念、光学品质以及耐用性，已成为Leica DMi8

的完美搭档。Andor 已将 Leica DMi8 完全集成在其产品

中，验证了光学、机械和软件的兼容性。

Andor 科技系统部主管 Mark Browne 博士

Maximum flexibility, functionality and innovation are the top priority for your research. Leica Microsystems partners with industry-leading companies, and with you.

CONTINUITY IN QUALITY

The Leica DMi8 is designed and manu-

factured with the quality you expect from

Leica Microsystems. Brilliant optics,

high-grade materials, robust design, ease

of use down to the smallest details,

and customer-centered service deliver

unmatched performance.

Check out Leica DMi8hardware components

Opto-mechanical documentation of the Infinity Port

As a high-performance solutions provider, the Systems Division at Andor has found the Leica DMi8 to be a perfect match with its unique open port concept, optical quality, and robustness. Andor has fully integrated the DMi8 into its product range, validating optical, mechanical, and software compatibility.

Dr. Mark Browne, Director, Systems Division, Andor Technology

CREATE YOUR OWN LEICA DMi8

The Leica DMi8 and LAS X are designed

for seamless integration of external

devices. Leica Microsystems invites you

to create your own version of the Leica

DMi8. The Infinity Port Connector, along

with complete optomechanical design

documentation, opens the light path to any

accessory you want to add.

Attach Thorlabs Cage Systems or Linos

Microbench or Nanobench components

directly to the Leica DMi8 by simply

adding them to the Infinity Port Connector.

For special applications, use 3rd party

software such as Metamorph (Molecular

Devices).

“To break a barrier, it’s good to have a partner like Leica.”

Prof. Stefan Hell Max Planck Institute for

Biophysical Chemistry, Göttingen, Germany

Maximum flexibility, functionality and innovation are the top priority for your research. Leica Microsystems partners with industry-leading companies, and with you.

CONTINUITY IN QUALITY

The Leica DMi8 is designed and manu-

factured with the quality you expect from

Leica Microsystems. Brilliant optics,

high-grade materials, robust design, ease

of use down to the smallest details,

and customer-centered service deliver

unmatched performance.

Check out Leica DMi8hardware components

Opto-mechanical documentation of the Infinity Port

As a high-performance solutions provider, the Systems Division at Andor has found the Leica DMi8 to be a perfect match with its unique open port concept, optical quality, and robustness. Andor has fully integrated the DMi8 into its product range, validating optical, mechanical, and software compatibility.

Dr. Mark Browne, Director, Systems Division, Andor Technology

CREATE YOUR OWN LEICA DMi8

The Leica DMi8 and LAS X are designed

for seamless integration of external

devices. Leica Microsystems invites you

to create your own version of the Leica

DMi8. The Infinity Port Connector, along

with complete optomechanical design

documentation, opens the light path to any

accessory you want to add.

Attach Thorlabs Cage Systems or Linos

Microbench or Nanobench components

directly to the Leica DMi8 by simply

adding them to the Infinity Port Connector.

For special applications, use 3rd party

software such as Metamorph (Molecular

Devices).

“To break a barrier, it’s good to have a partner like Leica.”

Prof. Stefan Hell Max Planck Institute for

Biophysical Chemistry, Göttingen, Germany

Maximum flexibility, functionality and innovation are the top priority for your research. Leica Microsystems partners with industry-leading companies, and with you.

CONTINUITY IN QUALITY

The Leica DMi8 is designed and manu-

factured with the quality you expect from

Leica Microsystems. Brilliant optics,

high-grade materials, robust design, ease

of use down to the smallest details,

and customer-centered service deliver

unmatched performance.

Check out Leica DMi8hardware components

Opto-mechanical documentation of the Infinity Port

As a high-performance solutions provider, the Systems Division at Andor has found the Leica DMi8 to be a perfect match with its unique open port concept, optical quality, and robustness. Andor has fully integrated the DMi8 into its product range, validating optical, mechanical, and software compatibility.

Dr. Mark Browne, Director, Systems Division, Andor Technology

CREATE YOUR OWN LEICA DMi8

The Leica DMi8 and LAS X are designed

for seamless integration of external

devices. Leica Microsystems invites you

to create your own version of the Leica

DMi8. The Infinity Port Connector, along

with complete optomechanical design

documentation, opens the light path to any

accessory you want to add.

Attach Thorlabs Cage Systems or Linos

Microbench or Nanobench components

directly to the Leica DMi8 by simply

adding them to the Infinity Port Connector.

For special applications, use 3rd party

software such as Metamorph (Molecular

Devices).

“To break a barrier, it’s good to have a partner like Leica.”

Prof. Stefan Hell Max Planck Institute for

Biophysical Chemistry, Göttingen, Germany