S C H R I F T E N V E R Z E I C H N I S

W I N F R I E D M Ä R Z

ORIGINALARBEITEN IN ZEITSCHRIFTEN MIT PEER REVIEW 1. März, W., Groß, W.: Separation of apolipoproteins of human very low density lipoproteins by

chromatofocusing. J. Clin. Chem. Clin. Biochem. 21, 459-462, 1983

2. März, W., Groß, W.: Quantification of human serum lipoprotein Lp(a): zone immunoelectrophoresis assay, a new sensitive method as compared to electroimmuno assay. Clin. Chim. Acta 134, 265-279, 1983

3. Groß, W., März, W., Ohlenschläger, G.: Quantifizierung von Apolipoprotein C-III im Serum mittels Zonenimmunoassay. GIT Lab.-Med. 6, 376-378, 1983

4. Groß, W., März, W.: Bestimmung von Apolipoprotein C-II im menschlichen Serum mittels einer neuen immunologischen Methode, dem Zonenimmunoassay. GIT Lab. Med. 7, 200-205, 1984

5. März, W., Groß, W., Gahn, G., Romberg, G., Taubert, H.D., Kuhl, H.: A randomized crossover comparison of two low-dose contraceptives: effects on serum lipids and lipoproteins. Am. J. Obstet. Gynecol. 153, 287-293, 1985

6. Kuhl, H., Gahn, G., Romberg, G., März, W., Taubert, H.D.: A randomized cross-over comparison of two low-dose oral contraceptives upon hormonal and metabolic parameters. I. Effects upon sexual hormone levels. Contraception 31, 583-593, 1985

7. Groß, W., März, W.: Evaluation of an electroimmunoassay for the simultaneous determination of apolipoproteins A-I and B in human sera. Ärztl. Lab. 32, 143-153, 1985

8. März, W., Groß, W.: Analysis of plasma lipoproteins by ultracentrifugation in a new fixed angle rotor: evaluation of a phosphotungstic acid/MgCl2 precipitation and a quantitative lipoprotein electrophoresis assay. Clin. Chim. Acta 160, 1-18, 1986

9. Groß, W., März, W.: Effect of free edetate on the determination of choline containing phospholipids. Ärztl. Lab. 33, 1-4, 1987 (Durchführung der Experimente, maMitarbeit am Manuskript)

10. März, W., Schenk, G., Groß, W.: Apolipoproteins C-II and C-III in serum quantified by zone immunoelectrophoresis. Clin. Chem. 33, 664-669, 1987

11. Jung-Hoffmann, C., März, W., Heidt, F., Groß, W., Kuhl, H.: Der Effekt zweier niedrigdosierter, Gestoden oder Desogestrel enthaltender Ovulationshemmer auf die Sexualhormone und den Fettstoffwechsel. Geburtsh. u. Frauenheilk. 48, 215-219, 1988

12. Grützmacher, P., März, W., Peschke, B., Groß, W., Schoeppe, W.: Lipoproteins and apolipoproteins during the progression of chronic renal desease. Nephron 50, 103-111, 1988

13. März, W., Groß, W.: Immunochemical evidence for the presence in human plasma of lipoproteins with apolipoprotein A-II as the major protein constituent. Biochim. Biophys. Acta 962, 155-158, 1988

14. März, W., Trommlitz, M., Groß, W.: Differential turbidimetric assay for subpopulations of lipoproteins containing apolipoprotein A-I. J. Clin. Chem. Clin. Biochem. 26, 573-578, 1988

15. März, W., Groß, W.: Ultracentrifugal determination of high-density lipoprotein subfractions HDL2 and HDL3 in a high capacity fixed angle rotor. Ärztl. Lab. 34, 265-270, 1988

16. Siekmeier, R., März, W., Groß, W.: Precipitation of LDL with sulfated polyanions: three methods compared. Clin. Chim. Acta 177, 221-230, 1988 (Konzeption der Studie, statistische Auswertung, Erstellung des Manuskripts)

17. März, W., Jung-Hoffmann, C., Heidt, F., Groß, W., Kuhl, H.: Changes in lipid metabolism during 12 months of treatment with two oral contraceptives containing 30 µg ethinylestradiol and 75 µg gestodene or 150 µg desogestrel. Contraception 41, 245-258, 1990

18. Kuhl, H., März, W., Jung-Hoffmann, C., Heidt, F., Groß, W.: Time-dependent alterations in lipid metabolism during treatment with low-dose oral contraceptives. Am. J. Obstet. Gynecol. 163, 363-369, 1990 (Durchführung der Lipoproteinmessungen mit Hilfe technischen Personals, statistische Auswertung)

19. Siekmeier, R., März, W., Groß, W.: Insufficient accuracy and specificity of polyanion precipitation methods for quantifying low-density lipoproteins. Clin. Chem. 36, 2109-2113, 1990 (Konzeption der Studie, statistische Auswertung, Erstellung des Manuskripts)

20. Löw-Friedrich, I., Grützmacher, P., März, W., Bergmann, M., Schoeppe, W.: Long-term echocardiographic examinations in chronic hemodialysis patients substituted with recombinant human erythropoietin. Blood Purif. 8, 272-278, 1990 (Dokumentation, statistische Auswertung)

21. Löw-Friedrich, I., Grützmacher, P., März, W., Bergmann, M., Schoeppe, W.: Therapy with recombinant human erythropoietin reduces cardiac size and improves heart function in chronic hemodialysis patients. Am. J. Nephrol. 11, 54-60, 1991

22. März, W., Cezanne, S., Groß, W.: Phenotyping of apolipoprotein E by immunoblotting in immobilized pH gradients. Electrophoresis 12, 59-63, 1991

23. Hasibeder, H., Staab, H.J., Seibel, K., Heibel, B., Schmidle, G., März, W.: Clinical pharmacology of the hypocholesterolemic agent K 12.148 (Lifibrol) in healthy volunteers. Eur. J. Clin. Pharmacol. 40 (Suppl. 1) S91-S94, 1991

24. März, W., Trommlitz, M., Scharrer, I., Groß, W.: Apolipoprotein (a) concentrations are not related to the risk of venous thrombosis. Blood Coagulation and Fibrinolysis 2, 595-599, 1991

25. Regeniter, A., Seiffert, U.B., Siede, W.H., März, W., Unkelbach, U., Rübsamen-Waigmann, H., Brede H.D.: HIV-induzierte Hypocholesterinämie. Münch. Med. Wschr. 133, 696-699, 1991

26. Peschke, B., März, W., Kachel, H.G., Grützmacher, P., Schoeppe, W., Scheuermann, E.H.: Intraindividuelle Serum Lipid Profile vor und nach Nierentransplantation. Zeitschrift für Transplantationsmedizin 3, 181-184, 1991

27. Müller, H.M., Diekstall, F.F., Schmidt, E., März, W., Canzler, H., Demeler, U.: Lipoprotein (a): a risk factor for retinal vascular occlusion. German J. Ophthalmol. 1, 338-341, 1992

28. Ruzicka, V., März, W., Russ, A., Groß, W.: Apolipoprotein B (Arg3500→Gln) allele specific polymeras chane reaction: large-scale screening of pooled blood samples. J. Lipid Res. 33, 1563-1567, 1992

29. Russ, A.P., Ruzicka, V., März, W., Appelhans, H., Groß, W.: Amplification and direct sequencing of a cDNA encoding human cytosolic 3-hydroxy-3-methylglutaryl-coenzyme A synthase. Biochim. Biophys. Acta 1132, 329-331, 1992

30. März, W., Ruzicka, V., Pohl, T., Usadel, K.H., Groß, W.: Familial defective apolipoprotein B-100: mild hypercholesterolaemia without atherosclerosis in a homozygous patient. Lancet 340, 1362, 1992 (Letter)

31. März, W., Peschke, B., Ruzicka, V., Siekmeier, R., Groß, W., Schoeppe, W., Scheuermann, E.: Type III hyperlipoproteinemia acquired by liver transplantation. Transplantation 55, 284-288, 1993

32. März, W., Ruzicka, V., Fisher, E., Russ, A.P., Schneider, W., Groß, W.: Typing of the 3' hypervariable region of the apolipoprotein B gene: approaches, pitfalls, and applications. Electrophoresis 14, 169-173, 1993

33. März, W., Siekmeier, R., Groß, E., Groß, W.: Determination of lipoprotein(a): enzyme immunoassay and immunoradiometric assay compared. Clin. Chim. Acta 214, 153-163, 1993

34. Chen, M., März, W., Manfras, B.J., Kühnl, P., Usadel, K.H., Böhm, B.O.: Rapid and simple subtyping of the HLA-DRB3 gene in Graves' disease using temperature-gradient gel electrophoresis. Hum. Immunol. 36, 199-203, 1993 (Mitarbeit an der Methodenentwicklung und am Manuskript)

35. März, W., Siekmeier, R., Scharnagl, H., Seiffert, U.B., Groß, W.: Fast lipoprotein chromatography: new method of analysis for plasma lipoproteins. Clin. Chem. 39, 2276-2281, 1993

36. März, W., Siekmeier, R., Groß, W., Kostner, G.M.: Determination of Lipoprotein(a): evaluation of three methods. Eur. J. Clin. Chem. Clin. Biochem. 31, 295-301, 1993

37. Ruzicka, V., März, W., Russ, A., Groß, W.: Immuno-PCR with a commercially available avidin system. Science 260, 698-699, 1993 (Konzept der Studie, Mitarbeit am Manuskript)

38. März, W., Feussner, G., Siekmeier, R., Donnerhak, B., Schaaf, L., Ruzicka, V., Groß, W.: Apolipoprotein E to B ratio: a marker for type III hyperlipoproteinaemia. Eur. J. Clin. Chem. Clin. Biochem. 31, 743-747, 1993

39. Russ, A.P., März, W., Ruzicka, V., Stein, U., Groß, W.: Rapid detection of the hypertension-associated Met235→Thr allele of the human angiotensinogen gene. Hum. Mol. Genet. 2, 609-610, 1993

40. Winkelmann, B.R., Ihnken, K., Beyersdorf, F., Eckel, L., Skupin, M., März, W., Herrmann, G., Spies, H., Schräder, R., Sievert, H.: Left main coronary artery stenosis after aortic valve replacement: genetic disposition for accelerated arteriosclerosis after injury of the intact human coronary artery? Coronary Artery Disease 4, 659-667, 1993

41. Ruzicka, V., März, W., Russ, A., Fisher, E., Mondorf, W., Groß, W.: Characterization of the gene for apolipoprotein E5-Frankfurt (Gln81→Lys, Cys112→Arg) by polymerase chain reaction, restriction isotyping, and temperature gradient gel electrophoresis. Electrophoresis 14, 1032-1037, 1993

42. März, W., Beckmann, A., Scharnagl, H., Siekmeier, R., Mondorf, U., Held, I., Schneider, W., Preissner K.T., Curtiss, L.K., Groß, W., Hüttinger, M.: Heterogeneous lipoprotein (a) size isoforms differ by their interaction with the low density lipoprotein receptor and the low density lipoprotein receptor-related protein/α2-macroglobulin receptor. FEBS Lett. 325, 271-275, 1993

43. März, W., Baumstark, M.W., Scharnagl, H., Ruzicka, V., Buxbaum, S., Herwig, J., Pohl, T., Russ, A., Schaaf, L., Berg, A., Böhles, H.-J., Usadel, K.H., Groß, W.: Accumulation of "small dense" low density lipoproteins (LDL) in a homozygous patient with familial defective apolipoprotein B-100 results from heterogenous interaction of LDL subfractions with the LDL receptor. J. Clin. Invest. 92, 2922-2933, 1993

44. Föhrenbach, R., Lohrer, H., März, W., Siekmeier, R., Evangeliou, A., Böhles, H.-J.: L-Carnitin bei Hochleistungssportlern unterschiedlicher Disziplinen. Österreich. J. Sportmed. 3, 67-75, 1993

45. Föhrenbach, R., März, W., Lohrer, H., Siekmeier, R., Evangeliou, A., Böhles, H.-J.: Der Einfluß von L-Carnitin auf den Lipidstoffwechsel von Hochleistungssportlern. Deutsche Zeitschrift für Sportmedizin 44, 349-356, 1993

46. Kuhl, H., März, W., Jung-Hoffmann, C., Weber, J., Siekmeier, R., Groß, W.: Effect on lipid metabolism of a biphasic desogestrel-containing oral contraceptive: divergent changes in apolipoprotein B and E and transitory decrease in Lp(a) levels. Contraception 47, 69-83, 1993

47. März, W., Grützmacher, P., Paul, D., Siekmeier, R., Schoeppe, W., Groß, W.: Effects of lovastatin (20-80 mg daily) on lipoprotein fractions in patients with severe primary hypercholesterolaemia. Int. J. Clin. Pharmacol. Ther. Toxicol. 32, 92-97, 1994

48. Winkelmann, B.R., Siekmeier, R., Kullmer, T., Proft, M., Schneider, W., März, W.: Genetischer Polymorphismus des Apolipoprotein E - ein Vergleich zwischen Koronarkranken und Gesunden. Herz/Kreisl. 26, 194-199, 1994Chen, M., März, W., Usadel, K.H., Scheurmann, E.H., Böhm, B.O.: Typing of the HLA-DRB3 gene by temperature gradient gel electrophoresis. Prediction of the resolution of four allelic fragments by computational simulation of DNA melting. J. Immunol. Meth. 168, 257-265, 1994

50. Groß, E., März, W., Siekmeier, R., Scharrer, I., Groß, W.: Isolation of lipoprotein (a) using the regenerate of a dextran sulfate cellulose LDL apheresis system. Protein Expres. Purif. 5, 112-117, 1994

51. Siekmeier, R., März, W., Kronenberger, H., Seiffert, U.B., Groß, W.: Effects of cigarette smoking on plasma lipids, apolipoproteins, and lipoprotein(a) in healthy subjects. Clin. Chem. 40, 1350-1351, 1994

52. März, W., Schmitz, H., Bach, G., Kirchgässler, K.U., Pfützner, A.: Mikronisiertes Fenofibrat. Wirksamkeit und Verträglichkeit in der Therapie von Dyslipidämien. Münch. Med. Wschr. 136, 690-694, 1994

53. Haak, T., März, W., Jungmann, E., Hausser, S., Siekmeier, R., Groß, W., Usadel, K.-H.: Elevated endothelin levels in patients with hyperlipoproteinemia. Clin. Invest. 72, 580-584, 1994

54. Durovic, S., März, W., Frank, S., Scharnagl, H., Baumstark, M.W., Zechner, R., Kostner, G.M.: Decreased binding of apolipoprotein (a) to familial defective apolipoprotein B-100 (Arg3500→Gln). A study of the assembly of recombinant apolipoprotein (a) with mutant low density lipoproteins. J. Biol. Chem. 269, 30320-30325, 1994

55. Ohm, T.G., Kirça, M., Bohl, J., Scharnagl, H., Groß, W., März, W.: Apolipoprotein E polymorphism influences not only cerebral senile plaque load but also Alzheimer-type neurofibrillary tangle formation. Neuroscience 66, 583-587, 1995

56. Scharnagl, H., März, W., Schliack, M., Löser, R., Groß, W.: A novel assay for cytosolic 3-hydroxy-3-methylglutaryl-coenzyme A synthase activity using reversed-phase ion-pair chromatography: demonstration that Lifibrol (K12.148) modulates the enzyme activity. J. Lipid. Res. 36, 622-627, 1995

57. März, W., Seydewitz, H., Winkelmann, B.R., Chen, M., Nauck, M., Witt, I.: Mutation in coagulation factor V associated with resistance to activated protein C in patients with coronary artery disease. Lancet 345, 526-527, 1995 (Letter)

58. Nauck, M., Winkler, K., Wittmann, C., Mayer, H., Luley, C., März, W., Wieland, H.: Direct determination of lipoprotein(a) cholesterol by ultracentrifugation and agarose gel electrophoresis with enzymatic staining for cholesterol. Clin. Chem. 41, 731-738, 1995

59. Nauck, M., Winkler, K., Siekmeier, R., Marangos, N., Richter, B., März, W., Wieland, H.: Pseudo-pseudohypertriglyceridemia: a case of increased free glycerol without evidence for glycerol kinase deficiency. Clin. Chem. 41, 619-620, 1995

60. Winkler, K., Nauck, M., Siekmeier, R., März, W., Wieland, H.: Determination of triglycerides in lipoproteins separated by agarose gel electrophoresis. J. Lipid Res. 36, 1839-1847, 1995

61. Kuhl, H., Jung-Hoffmann, C., Fitzner, M., März, W., Groß, W.: Short- and long-term effects on lipid metabolism of oral contraceptives containing 30 micrograms ethinylestradiol and 150 micrograms desogestrel or 3-keto-desogestrel. Horm. Res. 44, 121-125, 1995

62. Nauck, M., Winkler, K., März, W., Wieland, H.: Quantitative determination of high-, low-, and very-low-density lipoproteins and lipoprotein (a) by agarose gel electrophoresis and enzymatic cholesterol staining. Clin. Chem. 41, 1761-1767, 1995

63. Kullmer, T., Kneissl, G., Katova, T., Kronenberger, H., Urhausen, A., Kindermann, W., März, W., Meier-Sydow, J.: Experimental acute hypoxia in healthy subjects: evaluation of systolic and diastolic function of the left ventricle at rest and during exercise using echocardiography. Eur. J. Appl. Physiol. 70, 169-174, 1995

64. Zhang, Q., Cavanna, J., Winkelmann, B.R., Shine, B., Groß, W., März, W., Galton, D.J.: Common genetic variants of lipoprotein lipase that relate to lipid transport in patients with premature coronary artery disease. Clin. Genet. 48, 293-298, 1995

65. Nauck, M., März, W., Haas, B., Wieland, H.: Homogeneous assay for direct determination of high-density lipoprotein cholesterol evaluated. Clin. Chem. 42, 424-429, 1996

66. Feussner, G., Scharnagl, H., Scherbaum, C., Acar, J., Dobmeyer, J., Lohrmann, J., Wieland, H., März, W.: Apolipoprotein E5 (Glu212→Lys): increased binding to cell surface proteoglycans, but decreased uptake and lyosomal degradation in cultured fibroblasts. J. Lipid Res. 37, 1632-1645, 1996

67. Siekmeier, R., Wülfroth, P., Wieland, H., Groß, W., März, W.: Low-density lipoprotein susceptibility to in vitro oxidation in healthy smokers and nonsmokers. Clin. Chem. 42, 524-530, 1996

68. Siekmeier, R., März, W., Scharnagl, H., Nauck, M., Mayer, H., Wieland, H., Groß, W., Seiffert, U.B.: Bestimmung von Lipoprotein(a): Vergleich eines neuen latexverstärkten immunoturbidimetrischen Assay mit einem immunoradiometrischen Assay. J. Lab. Med. 20, 294-298, 1996

69. Winkelmann, B.R., Nauck, M., Klein, B., Russ, A.P., Böhm, B.O., Siekmeier, R., Ihnken, K., Verho, M., Groß, W., März, W.: Deletion polymorphism of the angiotensin I-converting enzyme gene is associated with increased plasma angiotensin-converting enzyme activity but not with increased risk of myocardial infarction and coronary artery disease. Ann. Intern. Med. 125, 19-25, 1996

70. Nauck, M., März, W., Wieland, H.: Adding albumin normalizes electrophoretic mobility of lipoproteins in sera with high concentrations of free fatty acids. Clin. Chem. 42, 1283-1285, 1996

71. Nauck, M., Krämer-Guth, A., Bartens, W., März, W., Wieland, H., Wanner, C.: Is the determination of LDL cholesterol according to Friedewald accurate in CAPD and HD patients?

72. Oemar, B.S., Werner, A., Garnier, J.-M., Do, D.-D., Godoy, N., Nauck, M., März, W., Rupp, J., Pech, M., Lüscher, T.F.: Human connective tissue growth factor is expressed in advanced atherosclerotic lesions. Circulation 95, 831-839, 1997

73. Schaefer, J.R., Scharnagl, H., Baumstark, M.W., Steinmetz, A., Schweer, H., Zech, L.A., Seyberth, H., Winkler, K., März, W.: Homozygous familial defective apolipoprotein B-100: enhanced removal of apolipoprotein E-containing VLDLs and decreased production of LDLs. Arterioscler. Thromb.Vasc. Biol. 17, 348-353, 1997

74. Lindh, M., Blomberg, M., Jensen, M., Basun, H., Lannfeldt, L., Engvall, B., Scharnagl, H., März, W., Wahlund, L.-O., Cowburn, R.F.: Cerebrospinal fluid apolipoprotein E (apoE) levels in Alzheimer´s disease patients are increased at follow up and show a correlation with levels of tau protein. Neurosci. Lett. 229, 85-88, 1997

75. Krämer-Guth, A., Quaschning, T., Pavenstädt, H., Galle, J., Nauck, M., Baumstark, M.W., Schollmeyer, P., März, W., Wanner, C.: Uptake and metabolism of lipoproteins from patients with diabetes mellitus type II by glomerular epithelial cells. Nephrol. Dial. Transplant. 12, 1336-1343, 1997

76. Krämer-Guth, A., Quaschning, T., Galle, J., Baumstark, M.W., Königer, M., Nauck, M., Schollmeyer, P., März, W., Wanner, C.: Structural and compositional modifications of diabetic low-density lipoproteins influence their receptor-mediated uptake by hepatocytes. Eur. J. Clin. Invest. 27, 460-468, 1997

77. Zhang, Q., Cavallero, E., Hoffmann, M.M., Cavanna, J., Kay, A., Charles, A., Braschi, S., März, W., Perlemuter, L., Jacotot, B., Galton, D.J.: Mutations at the lipoprotein lipase gene locus in subjects with diabetes mellitus, obesity and lipaemia. Clin. Sci. 93, 335-341, 1997

78. Winkelmann, B.R., Nauck, M., März, W.: Reliability of angiotensin-converting enzyme gene polymorphism in testing. Ann. Intern. Med. 126, 828, 1997 (Letter)

79. Nauck, M., März, W., Jarausch, J., Cobbaert, C., Sägers, A., Bernard, D., Delanghe, J., Honauer, G., Lehmann, P., Östrich, E., von Eckardstein, A., Walch, S., Wieland, H., Assmann, G.: Multicenter evaluation of a homogeneous assay for HDL-cholesterol without sample pretreatment. Clin. Chem. 43, 1622-1629, 1997

80. Wolf, R., Orszagh, M., März, W., Rösler, N., Berger, M., Bauer, J.: Case study. Revision of an Alzheimer´s diagnosis in a patient with an almost normal CT scan: why strategic vascular lesions may be overlooked. Alzheimer´s Research 3, 73-76, 1997Bommer, C., Werle, E., Walter-Sack, I., Keller, C., Gehlen, F., Wanner, C., Nauck, M., März, W., Wieland, H., Bommer, J.: D-tyroxine reduces lipoprotein(a) serum concentration in dialysis patients. J. Am. Soc. Nephrol. 9, 90-96, 1998 März, W., Hoffmann, M.M., Scharnagl, H., Fisher, E., Chen, M., Nauck, M.S., Feussner, G., Wieland, H.: Apolipoprotein E2 (Arg136→Cys) mutation in the receptor binding domain of apoE is not associated with dominant type III hyperlipoproteinemia. J. Lipid. Res. 39, 658-669, 1998

83. Feussner, G., Feussner, V., Hoffmann, M.M., Lohrmann, J., Wieland, H., März, W.: Molecular basis of type III hyperlipoproteinemia. Hum. Mutat. 11, 417-423, 1998

84. Zotz, R.B., Winkelmann, B.R., Nauck, M., Giers, G., Maruhn-Debowski, B., März, W., Scharf, R.E.: Polymorphism of platelet membrane glycoprotein IIIa: human platelet antigen 1b (HPA-1b/PIA2) is an inherited risk factor for premature myocardial infarction in coronary artery disease. Thromb. Haemost. 79, 731-735, 1998

85. Nauck, M.S., Nissen, H., Hoffmann, M.M., Herwig, J., Pullinger, C.R., Averna, M., Geisel, J., Wieland, H., März, W.: Detection of mutations in the apolipoprotein CII gene by denaturing gradient gel electrophoresis. Identification of the splice site variant apolipoprotein CII-Hamburg in a patient with severe hypertriglyceridemia. Clin. Chem. 44, 1388-1396, 1998

86. Nauck, M., März, W., Wieland, H.: New immunoseparation-based homogeneous assay for HDL-cholersterol compared with three homogeneous and two heterogeneous methods for HDL-cholesterol. Clin. Chem. 44, 1443-1451, 1998

87. Cobbaert, C., Zwang, L., Ceriotti, F., Modenese, A., Cremer, P., Herrmann, W., Hoß, G., Jarausch, J., Türk, R., März, W., Nauck, M.: Reference standardization and triglyceride interference of a new homogeneous HDL-cholesterol assay compared with al former chemical precipitation assay. Clin. Chem. 44, 779-789, 1998

88. Braun, J., März, W., Winkelmann, B.R., Donner, H., Usadel, K.H., Badenhoop, K.: Tumour necrosis factor ß alleles and hyperinsulinaemia in coronary artery disease. Eur. J. Clin. Invest. 28, 538-542, 1998

89. Hennermann, J.B., Herwig, J., März, W., Asskali, F., Böhles, H.J.: Lipid and lipoprotein profiles in children with familial hypercholesterolaemia: effects of therapy. Eur. J. Pediatr. 157, 912-918, 1998

90. Szucs, T.D., Guggenberger, G., Berger, K., März, W., Schäfer, J.R.: Pharmakoökonomische Bewertung von Pravastatin in der Sekundärprävention der koronaren Herzkrankheit bei Patienten mit durchschnittlichen Cholesterinwerten. Herz 23, 319-329, 1998

91. Müller, W., Meske, V., Berlin, K., Scharnagl, H., März, W., Ohm, T.G.: Apolipoprotein E isoform increase intracellular Ca2+ differentially through a ω-Agatoxin IVa-sensitive Ca2+-channel. Brain Pathol. 8, 641-653, 1998

92. Bissé, E., Zorn, N., Eigel, A., Lizama, M., Huaman-Guillen, P., März, W., Van Dorsselaer, A., Wieland, H.: Hemoglobin Rambam (ß69[E13]Gly→Asp), a pitfall in the assessment of diabetic control: characterization by electrospray mass spectrometry and HPLC. Clin. Chem. 44, 2172-2177, 1998

93. Szucs, T.D., März, W.: Cost effectiveness of coronary prevention. Eur. Heart J. 20, 317, 1999 (Letter)

94. Winkler, K., Scharnagl, H., Tisljar, U., Hoschützky, H., Friedrich, I., Hoffmann, M.M., Hüttinger, M., Wieland, H., März, W.: Competition of Aß amyloid peptide and apolipoprotein E for receptor-mediated endocytosis. J. Lipid Res. 40, 447-455, 1999

95. Winkelmann, B.R., Russ, A.P., Nauck, M., Klein, B., Böhm, B.O., Maier, V., Zotz, R., Matheis, G., Wolf, A., Wieland, H., Groß, W., Galton, D.J., März, W.: Angiotensinogen M235T polymorphism is associated with plasma angiotensinogen and cardiovascular disease. Am. Heart J. 137, 698-705, 1999

96. März, W., Wollschläger, H., Klein, G., Neiß, A., Wehling, M.: Safety of low density lipoprotein cholesterol reduction with Atorvastatin versus Simvastatin in a coronary heart disease population (the TARGET TANGIBLE Trial). Am. J. Cardiol. 84, 7-13, 1999

97. Winkler, K., Schäfer, J.R., Klima, B., Nuber, C., Sattler, A., Friedrich, I., Köster, W., Steinmetz, A., Wieland, H., März, W.: Lifibrol enhances low density lipoprotein apolipoprotein B-100 turnover in patients with hypercholesterolemia and mixed hyperlipidemia. Atherosclerosis 144, 167-175, 1999

98. Nauck, M.S., Gierens, H., Nauck, M.A., März, W., Wieland, H.: Rapid genotyping of human platelet antigen 1 (HPA-1) with fluorophore-labelled hybridization probes on the LightCyclerTM. Br. J. Haematol. 105, 803-810, 1999

99. Wanner, C., Krane, V., Ruf, G., März, W., Ritz, E., for Die Deutsche Diabestes Dialyse Studie Investigators: Rationale and design of a trial improving outcome of type 2 diabetics on hemodialysis: The 4D study. Kidney Int. 56 (Suppl. 71), S222-S226, 1999

100. Nauck, M., Glatt, L., März, W., Feussner, G., Wieland, H.: Simple precipitation-based method for the screening of type III hyperlipoproteinemia. Clin. Chem. 45, 909-911, 1999

101. Larson, I., Hoffmann, M.M., Ordovas, J.M., Schaefer, E.J., März, W., Kreuzer, J.: The lipoprotein lipase HindIII polymorphism: association with total cholesterol and LDL-cholesterol, but not with HDL and triglycerides in 342 females. Clin. Chem. 45, 963-968, 1999

102. Fisher, E., Scharnagl, H., Hoffmann, M.M., Kusterer, K., Wittmann, D., Wieland, H., Groß, W., März, W.: Mutations in the apolipoprotein (apo) B-100 receptor-binding region: detection of apo B-100 (arg3500→trp) associated with two new haplotypes and evidence that apo B-100 (glu3405→ gln) diminishes receptor-mediated uptake of LDL. Clin Chem. 45, 1026-1038, 1999

103. Nauck, M.S., Wieland, H., März W.: Rapid homogeneous genotyping of the 4G/5G polymorphism in the promoter region of the PAI-1 gene by fluorescence resonance energy transfer and probe melting curves. Clin. Chem. 45, 1141-1147, 1999

104. Kusterer, K., Pohl, T., Fortmeyer, H.-P., März, W., Scharnagl, H., Oldenburg, A., Angermüller, S., Fleming, I., Usadel, K.H., Busse, R.: Chronic selective hypertriglyceridemia impairs endothelium-dependent vasodilation in rats. Cardiovasc. Res. 42, 783-793, 1999

105. Nauck, M., Neumann, I., März, W., Wieland, H.: A new liquid homogeneous assay for the determination of HDL-cholesterol. A comparison to precipitation with phosphotungstic acid/MgCl2 and a lyophilized homogeneous assay. Clin. Chem. Lab. Med. 37, 537-543, 1999

106. Ohm, T.G., Scharnagl, H., März, W., Bohl, J.: Apolipoprotein E isoforms and the development of low and high Braak stages of Alzheimer's disease-related lesions. Acta Neuropathol. 98, 273-280, 1999

107. Scharnagl, H., Tisljar, U., Winkler, K., Hüttinger, M., Nauck, M.A., Groß, W., Wieland, H., Ohm, T.G., März, W.: The ßA4 amyloid peptide complexes to and enhances the uptake of ß-very low density lipoproteins by the low density lipoprotein receptor-related protein and heparan sulfate proteoglycans pathway. Lab. Invest. 79, 1271-1286, 1999

108. Koenig, W., Rothenbacher, D., Hoffmeister, A., Miller, M., Bode, G., Adler, G., Hombach, V., März, W., Pepys, M.B., Brenner, H.: Infection with Helicobacter pylori is not a major independent risk factor for stable coronary heart disease. Lack of a role of Cytotoxin-associated protein a-positive strains and absence of a systemic inflammatoriy response. Circulation 100, 2326-2331, 1999

109. Wetzka, B., Winkler, K., Kinner, M., Friedrich, I., März, W., Zahradnik, H.P.: Altered lipid metabolism in preeclampsia and HELLP syndrome: Links to enhanced platelet reactivity and fetal growth. Semin. Thromb. Haemost. 25, 455-462, 1999

110. Nauck, M.S., Nauck, M.A., Nauck, M., März, W., Wieland, H.: Six methods for the determination of C-peptide evaluated, Clin. Chem. Lab. Med. 37: 745-752, 1999

111. Nauck, M., Graziani, M.S., Jarausch, J., Bruton, D., Cobbaert, C., Cole, T.G., Colella, F., Lefevre, F., Gillery, P., Haas, B., Law, T., König, M., Macke, M., März, W., Meier, C., Riesen, W., van Vliet, M., Wieland, H., Rifai, N.: A new liquid homogeneous assay for HDL cholesterol determination evaluated in seven laboratories in Europe and the United States. Clin. Chem. Lab. Med. 37, 1067-1076, 1999

112. Schuler-Lüttmann, S., Zhu, Y., Hoffmann, M.M., März, W., Feussner, G., Wieland, H., Assmann, G., von Eckardstein, A.: Cholesterol efflux from normal and Tangier disease fibroblasts into normal, high density lipoprotein-deficient, and apolipoprotein E-deficient plasmas. Metabolism 49, 770-777, 2000

113. Nauck, M., Hoffmann, M.M., Wieland, H., März, W.: Evaluation of the apo E genotyping kit on the Light-Cycler. Clin. Chem. 46, 722-724, 2000

114. Winkler, K., Schaefer, J.R., Klima, B., Nuber, C., Friedrich, I., Köster, W., Gierens, H., Scharnagl, H., Soufi, M., Wieland, H., März, W.: HDL steady state levels are not affected, but HDL apoA-I turnover is enhanced by Lifibrol in patients with hypercholesterolemia and mixed hyperlipidemia. Atherosclerosis 150, 113-120, 2000

115. Nauck, M.S., Scharnagl, H., Nissen, H., Schürmann, C., Matern, D., Nauck, M.A., Wieland, H., März, W.: FH-Freiburg: a novel missense mutation (C317Y) in growth factor repeat A of the low density lipoprotein receptor gene in a German patient with homozygous familial hypercholesterolemia. Atherosclerosis 151, 525-534, 2000

116. Nauck, M., Roser, M., März, W., Wieland, H.: Additional comments on pre-analytical aspects of lipoprotein measurement (Letter). Clin. Lab. 46, 301-302, 2000

117. Schaefer, J.R., Winkler, K., Schweer, H., Hoffmann, M.M., Soufi, M., Scharnagl, H., Maisch, B., Wieland, H., Steinmetz, A., März, W.: Increased production of HDL apoA-I in homozygous familial defective apoB-100. Arterioscler. Thromb. Vasc. Biol. 20, 2000, 1796-1799

118. Gierens, H., Nauck, M., Roth, M., Schinker, R., Schürmann, C., Scharnagl, H., Neuhaus, G., Wieland, H., März W.: Interleukin-6 stimulates LDL receptor gene expression via activation of sterol-responsive and Sp1 binding elements. Arterioscler. Thromb. Vasc. Biol. 20, 1777-1783, 2000

119. Nauck, M., März, W., Wieland, H.: Is lipoprotein(a) cholesterol a significant indicator of cardiovascular risk ? (Letter) Clin. Chem. 46, 436-437, 2000

120. Siekmeier, R., Groß, W., März, W.: Determination of Pravastatin by high performance liquid chromatography. Int. J. Clin. Pharmacol. Ther. 38, 419-425, 2000

121. Szucs, T.D., Berger, K., März, W., Schäfer, J.R.: Kosteneffektivität von Pravastatin in der koronaren Sekundärprävention bei Patienten mit Myokardinfarkt und instabiler Angina pectoris in Deutschland. Eine Analyse auf der Grundlage der LIPID-Studie. Herz 25, 487-494, 2000

122. Nauck, M., Wieland, H., März, W.: Evaluation of the Roche Diagnostics LightCycler-Apo B 3500 mutation detection kit. Clin. Chem. Lab. Med. 38, 667-671, 2000

123. Nauck, M.S., März, W., Wieland, H.: Evaluation of the Roche Diagnostics LightCycler-Factor V Leiden Mutation Detection Kit and the LightCycler-Prothrombin Mutation Detection Kit. Clin. Biochem. 33, 213-216, 2000

124. Gibb, G.M., Pearce, J., Betts, J.C., Lovestone, S., Hoffmann, M.M., März, W., Blackstock, W.P., Anderton, B.H.: Differential effects of apolipoprotein E isoforms on phosphorylation at specific sites on tau by glycogen synthase kinase-3β identified by nano-electrospray mass spectrometry. FEBS Lett. 485, 99-103, 2000 Scharnagl, H., Schliack, M., Löser, R., Nauck, M., Gierens, H., Jeck, N., Wieland, H., Groß, W., März, W.: The effects of Lifibrol (K12.148) on the cholesterol metabolism of cultured cells: evidence for sterol independent stimulation of the LDL receptor pathway. Atherosclerosis 153, 69-80, 2000

126. März, W., Siekmeier, R., Müller, H.-M., Wieland, H., Groß, W., Olbrich, H.-G.: Effects of Lovastatin and Pravastatin on the survival of hamsters with inherited cardiomyopathy. J. Cardiovasc. Pharmacol. Ther. 5, 275-279, 2000

127. Winkler, K., Wetzka, B., Hoffmann, M.M., Friedrich, I., Kinner, M., Baumstark, M.W., Wieland, H., März, W., Zahradnik, H.P.: Low density lipoprotein (LDL) subfractions during pregnancy: accumulation of buoyant LDL with advancing gestation. J. Clin. Endocrinol. Metab. 85, 4543-4550, 2000

128. Huber, G., März, W., Martin, J.R., Malherbe, P., Richards, J.G., Sueoka, N., Ohm, T., Hoffmann, M.M.: Characterization of transgenic mice expressing apolipoprotein E4(C112R) and apolipoprotein E4 (L28P; C112R). Neuroscience 101, 211-218, 2000

129. Hoffmann, M.M., Jacob, S., Luft, D., Schmülling, R.-M., Rett, K., März, W., Häring, H.-U., Matthaei, S.: Type I hyperlipoproteinemia due to a novel loss of function mutation of lipoprotein lipase, Cys239→Trp, associated with recurrent severe pancreatitis. J. Clin. Endocrinol. Metab. 85, 4795-4798, 2000

130. Nauck, M., Stein, U., Karger, S., März, W., Wieland, H.: Rapid detection of the C3435T polymorphism of multidrug resistance gene 1 using fluorogenic hybridzation probes. Clin. Chem. 46, 1995-1997, 2000

131. Fisher, E., März, W., Groß, W.: High prevalence of FDB3500 mutation in the Swiss population. Atherosclerosis 153, 519-521, 2000 (Letter)

132. Hoffmann, M.M., Scharnagl, H., Panagiotou, E., Banghard, W.T., Wieland, H., März W.: Diminished LDL receptor and high heparin binding of apolipoprotein E2 Sendai associated with lipoprotein glomerulopathy. J. Am. Soc. Nephrol. 12, 524-530, 2001

133. Masana, L.I., Febrer, G., Cavanna, J., Baroni, M.G., März, W., Hoffmann, M.M., Shine, B., Galton, D.J.: Common genetic variants that relate to disorders of lipid transport in Spanish subjects with premature coronary artery disease. Clin. Sci. 100, 183-190, 2001

134. Hoffmann, M.M., Scharnagl, H., Köster, W., Winkler, K., Wieland, H., März, W.: Apolipoprotein E1-Baden (Arg180→Cys): a new apolipoprotein E variant associated with hypertriglyceridemia. Clin. Chim. Acta, 303, 41-48, 2001

135. Hoffmeister, A., Rothenbacher, D., Bode, G., Persson, K., März, W., Nauck, M.A., Brenner, H., Hombach, V., Koenig, W.: Current infection with Helicobacter pylori, but not seropositivity to Chlamydia pneumoniae or cytomegalovirus, is associated with an atherogenic, modified lipid profile. Ateroscler. Thromb. Vasc. Biol. 21, 427-432, 2001

136. Ritzel, R., Schulte, M., Porksen, N., Nauck, M.S., Holst, J.J., Juhl, C., März W., Schmitz, O., Schmiegel, W.H., Nauck, M.A.: Glucagon-like peptide 1 increases secretory burst mass of pulsatile insulin secretion in patients with type 2 diabetes and impaired glucose tolerance. Diabetes 50, 776-784, 2001

137. März, W., Scharnagl, H., Abletshauser, C., Hoffmann, M.M., Berg, A., Keul, J., Wieland, H., Baumstark, M.W.: Fluvastatin lowers atherogenic, dense low-density lipoproteins in postmenopausal women with the atherogenic lipoprotein phenotype. Circulation, 103, 1942-1948, 2001

138. Kojro, E., Gimpl, G., Lammich, S., März, W., Fahrenholz F.: Low cholesterol stimulates the nonamyloidogenic pathway by its effect on the alpha-secretase ADAM 10. Proc. Natl. Acad. Sci. USA 98, 5815-5820, 2001

139. Winkelmann, B.R., März, W., Böhm, B.O., Zotz, R., Hager, J., Hellstern, P., Senges, J. on behalf of the LURIC study group: Rationale and design of the LURIC study – a resource for functional genomics, pharmacogenomics and long-term prognosis of cardiovascular disease. Pharmacogenomics 2 (Suppl. 1), S1-S73, 2001

140. Scharnagl, H., Nauck, M., Wieland, H., März, W.: The Friedewald formula underestimates LDL cholesterol at low concentrations. Clin. Chem. Lab. Med., 39, 426-431, 2001

141. Brenner, H., Rothenbacher, D., Bode, G., März, W., Hoffmeister, A., Koenig, W.: Coronary heart disease risk reduction in a predominantly beer-drinking population. Epidemiology 12, 390-395, 2001

142. Nauck, M., Gierens, H., März, W., Wieland, H.: Rapid detection of a common dihydropyrimidine dehydrogenase mutation associated with 5-fluorouracil toxcity and congenital thymine uraciluria using fluorogenic hybridization probes. Clin. Biochem. 34, 103-105, 2001

143. Yates, R.A., Wong, J., Seiberling, M., Merz, M., März, W., Nauck, M.: The effect of anastrozole on the single-dose pharmacokinetics and anticoagulant activity of warfarin in healthy volunteers. Br. J. Clin. Pharmacol. 51, 429-435, 2001

144. Nauck, M.S., Köster, W., Dörfer, K., Eckes, J., Scharnagl, H., Gierens, H., Nissen, H., Nauck, M.A., Wieland, H., März, W.: Identification of recurrent and novel mutations in the LDL receptor gene in German patients with familial hypercholesterolemia. Hum. Mutat. 18, 165-166, 2001

145. Scharnagl, H., Schinker, R., Gierens, H., Nauck, M., Wieland, H., März, W.: Effect of atorvastatin, simvastatin, and lovastatin on the metabolism of cholesterol and triacylglycerides in HepG2 cells. Biochem. Pharmacol. 62, 1545-1555, 2001

146. Winkelmann, B.R., Böhm, B.O., Nauck, M.S., Kleist, P., März, W., Verho, N.K., Ranjith, N., Kneissl, G.: Cigarette smoking is independently associated with markers of endothelial dysfunction and hyperinsulinaemia in non-diabetic individuals with coronary artery disease. Curr. Med. Res. Opin. 17, 132-141, 2001

147. Park, J.-W., Siekmeier, R., Merz, M., Krell, B., Harder, S., März, W., Seidel, D., Schüler, S., Groß, W.: Pharmacokinetics of pravastatin in heart-transplant patients taking cyclosprin A. Int. J. Clin. Pharmacol. Ther. 40, 439-450, 2002

148. Rothenbacher, D., Fischer, H.G., Hoffmeister, A., Hoffmann, M.M., März, W., Bode, G., Rosenthal, J., Koenig, W., Brenner, H.: Homocysteine and methylenetetrahydrofolate reductase genotype: association with risk of coronary heart disease and relation to inflammatory, hemostatic, and lipid parameters. Atherosclerosis 162, 193-200, 2002

149. Winkler, K., Friedrich, I., Baumstark, M.W., Wieland, H., März, W.: Pioglitazone reduces atherogenic dense low density lipoprotein (LDL) particles in patients with type 2 diabetes mellitus. Br. J. Diab. Vasc. Dis. 2, 143-148, 2002

150. Kay, A., März, W., Hoffmann, M.M., Zhang, Q., Masana, L., Cavanna, J., Baroni, M.G., Shine, B., Galton D.J.: Coronary artery disease and dyslipidemia within Europe: genetic variants in lipid transport gene loci in German subjects with premature coronary artery disease. Atherosclerosis Suppl. 3, 27-33, 2002

151. Ruof, J., Klein, G., März, W., Wollschläger, H., Neiss, A., Wehling M.: Lipid-lowering medication for secondary prevention of coronary heart disease in a German outpatient population: the gap between treatment guidelines and real life treatment patterns. Prev. Med. 35, 48-53, 2002

152. Koenig, W., Khuseyinova, N., Hoffmann, M.M., März W., Fröhlich, M., Hoffmeister, A., Brenner, H., Rothenbacher, D.: CD14 C(-260)→T polymorphism, plasma levels of the soluble endotoxin receptor CD14, their association with chronic infections and risk of stable coronary artery disease. J. Am. Coll. Cardiol. 40, 34-42, 2002

153. Abletshauser, C., Klüßendorf, D., Schmidt, A., Winkler, K., März, W., Buddecke, E. Malmsten, M., Siegel, G.: Biosensing of arteriosclerotic nanoplaque formation and interaction with an HMG-CoA reductase inhibitor. Acta Physiol. Scand. 176, 131-145, 2002

154. Wiemer, J., Winkler, K., Baumstark M., März, W., Scherberich, J.E.: Influence of low molecular weight heparin compared to conventional heparin for anticoagulation during haemodialysis on low density lipoprotein subclasses. Nephrol. Dial. Transplant. 17, 2231-2238, 2002

155. Nauck, M., Winkelmann, B.R., Hoffmann, M.M., Böhm, B.O., Wieland, H., März, W.: C(-260)T polymorphism in the promoter of the CD14 gene is not associated with coronary artery disease and myocardial infarction in the Ludwigshafen Risk and Cardiovascular Health (LURIC) study. Am. J. Cardiol. 90, 1249-1252, 2002

156. Nauck, M., Winkelmann, B.R., Hoffmann, M.M., Böhm, B.O., Wieland H., März, W.: The interleukin-6 G(-174)C promoter polymorphism in the LURIC cohort: no association with plasma interleukin-6, coronary artery disease, and myocardial infarction. J. Mol. Med. 80, 507-513, 2002

157. Winkler, K., Abletshauser, C., Hoffmann, M.M., Friedrich, I., Gläser, R., Baumstark, M.W., Wieland, H., März, W.: Effect of fluvastatin slow-release on low density lipoprotein (LDL) subfractions in patients with type 2 diabetes mellitus: baseline LDL profiles determines specific mode of action. J. Clin. Endocrinol. Metab. 87, 5485-5490, 2002

158. Nauck, M.S., Scharnagl, H., Nissen, H., Schurmann, C., Matern, D., Nauck, M.A., Wieland, H., März, W.: Corrigendum to 'FH-Freiburg: a novel missense mutation (C317Y) in growth factor repeat A of the low density lipoprotein receptor gene in a German patient with homozygous familial hypercholesterolemia' (Atherosclerosis 151, 525-534, 2000 [Journal Article]). Atherosclerosis 167, 173, 2003

159. Spaniol, M., Kaufmann, P., Beier, K., Wüthrich, J., Török, M., Scharnagl, H., März, W., Krähenbühl, S.: Mechanisms of liver steatosis in rats with systemic carnitine deficiency due to treatment with trimethylhadraziniumpropionate. J. Lipid Res. 44, 144-153, 2003

160. The ENCORE Investigators: Effect of nifedipine and cerivastatin on coronary endothelial function in patients with coronary artery disease. The ENCORE I Study (Evaluation of Nifedipine and Cerivastatin On Recovery of coronary Endothelial function) Circulation 107, 422-428, 2003

161. Winkler, K., Wetzka, B., Hoffmann, M.M., Friedrich, I., Kinner, M., Baumstark, M.W., Zahradnik, H.-P., Wieland, H., März, W.: Triglyceride-rich lipoproteins are associated with hypertension in preeclampsia. J. Clin. Endocrinol. Metab. 88, 1162-1166, 2003

162. Ljungberg, M.C., Asuni, A., Pearce, J., Dayanandan, R., März, W., Hoffmann, M.M., Bertrand, P., Siest, G., Rupniak, H.T.R., Anderton, B.H., Huettinger, M., Lovestone S.: Apolipoprotein E (apoE) uptake and distribution in mammilian cell lines is dependent upon source of apoE and can be monitored in living cells. Neurosci. Lett. 341, 69-73, 2003

163. Taubert, G., Winkelmann, B.R., Schleiffer, T., März, W., Winkler, R., Gök, R., Klein, B., Schneider, S., Böhm, B.O.: Prevalence, predictors, and consequences of unrecognized diabetes mellitus in 3266 patients scheduled for coronary angiography. Am. Heart J. 145, 285-291, 2003

164. Marx, N., Imhof, A., Fröhlich, J., Siam, L., Ittner, J., Wierse, G., Schmidt, A., März, W., Hombach, V., Koenig, W.: Effect of rosiglitazone treatment on soluble CD40L in patients with type 2 diabetes and coronary artery disease. Circulation 107, 1954-1957, 2003

165. Winkler, K., Konrad, T., Füllert, S., Friedrich, I., Destani, R., Baumstark, M.W., Krebs, K., Wieland, H., März, W.: Pioglitazone reduces atherogenic dense LDL particles in nondiabetic patients with arterial hypertension: a double-blind, placebo-controlled study. Diabetes Care 26, 2588-2594, 2003 7.501 {

166. Manzoni, C., Duranti, M., Eberini, I., Scharnagl, H., März, W., Castiglioni, S., Lovati, M.R.: Subcellular localization of soybean 7S globulin in HepG2 cells and LDL receptor up-regulation by its alpha' constituent subunit. J. Nutr. 133, 2149-2155, 2003 3.321 {Winkelmann, B.R., Hoffmann, M.M., Nauck, M., Kumar, A.M., Nandabalan, K., Judson, R.S., Böhm, B.O., Tall, A.R., Ruaño, G., März, W.: Haplotypes of the cholesteryl ester transfer protein gene predict lipid-modifying response to statin therapy. Pharmacogenomics J. 3, 284-296, 2003

168. März, W., Winkler, K., Nauck, M., Böhm, B.O., Winkelmann, B.R.: Effects of statins on C-reactive protein and on interleukin 6 (The Ludwigshafen Risk and Cardiovascular Health Study). Am. J. Cardiol. 92, 305-308, 2003

169. Bugert, P., Hoffmann, M.M., Winkelmann, B.R., Vosberg, M., Jahn, J., Entelmann, M., Katus, H.A., März, W., Mansmann, U., Böhm, B.O., Goerg, S., Klüter, H.: The variable number of tandem repeat polymorphism in the P-selectin glycoprotein ligand-1 gene is not associated with coronary heart disease. J. Mol. Med. 81, 495-501, 2003 4.101 {

170. Imhof, A., Rothenbacher, D., Khuseyinova, N., Hoffmeister, A., März, W., Nauck, M., Scharnagl, H., Koenig, W., Brenner, H.: Plasma lipoprotein Lp(a), markers of hemostasis and inflammation, and risk and severity of coronary heart disease. Eur. J. Cardiovasc. Prev. Rehabil. 10, 362-370, 2003

171. Miserez, A.R., Scharnagl, H., Muller, P.Y., Mirsaidi, R., Stähelin, H.B., Monsch, A., März, W., Hoffmann, M.M.: Apolipoprotein E3Basel: new insights into a highly conserved protein region. Eur. J. Clin. Invest. 33, 677-685, 2003

172. Lang, T.H., Toller, W.G., Gütl, M., Mahla, E., Metzler, H., Rehak, P.H., März, W., Halwachs-Baumann, G.: Different effects of abciximab and cytochalasin D on clot strength in thrombelastography. J. Thromb. Haemost. 2, 147-153, 2004

173. Scharnagl, H., Kist, H., Busse-Grawitz, A., Koenig, W., Wieland, H., März, W.: Effect of Helicobacter pylori eradication on high-density lipoprotein cholesterol. Am. J. Cardiol. 93, 219-220, 2004

174. Scharnagl, H., Petersen, G., Nauck, M., Teichmann, A.T., Wieland, H., März, W.: Double-blind, randomized study comparing the effects of two monophasic oral contraceptives containing ethinylestradiol (20 µg or 30 µg) and levonorgestrel (100 µg or 150 µg) on lipoprotein metabolism. Contraception 69, 105-113, 2004

175. Wetzka, B., Hoffmann, M.M., Friedrich, I., Baumstark, M.W., Zahradnik, H.-P.,März, W., Winkler, K.: Transient remnant removal disease in acute fatty liver of pregnancy. Hypertens. Pregnancy 23, 143-153, 2004

176. Soufi, M., Sattler, A.M., März, W., Starke, A., Herzum, M., Maisch, B., Schaefer, J.R.: A new but frequent mutation of ApoB-100 – apoB His3543Tyr. Atherosclerosis 174, 11-16, 2004

177. Winkler, K., Weltzien, P., Friedrich, I., Schmitz, H., Nickell, H.H., Hauck, P., Hoffmann, M.M., Baumstark, M.W., Wieland, H., März, W.: Qualitative effect of fenofibrate and quantitative effect of atorvastatin on LDL profile in combined hyperlipidemia with dense LDL. Exp. Clin. Endocrinol. Diabetes 112, 241-247, 2004

178. Scharnagl, H., Winkler, K., Mantz, S., Baumstark, M.W., Wieland, H., März, W.: Inhibition of HMG-CoA reductase with Cerivastatin lowers dense low density lipoproteins in patients with elevated fasting glucose, impaired glucose tolerance and type 2 diabetes mellitus. Exp. Clin. Endocrinol. Diabetes 112, 269-277, 2004

179. Winkler, K., Abletshauser, C., Friedrich, I., Hoffmann, M.M., Baumstark, M.W., Wieland, H., März, W.: Fluvastatin slow-release lowers platelet-activating factor acetyl hydrolase activity: a placebo-controlled trial in patients with type 2 diabetes. J. Clin. Endocrinol. Metab. 89, 1153-1159, 2004

180. März, W., Nauck, M., Hoffmann, M.M., Nagel, D., Böhm, B.O., Koenig, W., Rothenbacher, D., Winkelmann, B.R.: G(-30)A polymorphism in the pancreatic promoter of the glucokinase gene associated with angiographic coronary artery disease and type 2 diabetes mellitus. Circulation 109, 2844-2849, 2004

181. Patsouris, D., Mandard, S., Voshol, P.J., Escher, P., Tan, N.S., Havekes, L.M., Koenig, W., März, W., Tafuri, S., Wahli, W., Müller, M., Kersten, S.: PPARalpha governs glycerol metabolism. J. Clin. Invest. 114, 94-103, 2004

182. Mangge, H., Schauenstein, K., Stroedter, L., Griesl, A., März, W., Borkenstein, M.: Low grade inflammation in juvenile obesity and type 1 diabetes associated with early signs of atherosclerosis. Exp. Clin. Endocrinol. Diabetes 112, 378-382, 2004

183. März, W., Scharnagl, H., Winkler, K., Tiran, A., Nauck, M., Böhm, B.O., Winkelmann, B.R.: Low density lipoprotein triglycerides associated with low grade systemic inflammation, adhesion molecules and angiographic coronary disease. (The Ludwigshafen Risk and Cardiovascular Health Study). Circulation 110, 3068-3074, 2004

184. März, W., Scharnagl, H., Böhm, B.O., Winkelmann, B.R.: The apolipoprotein E polymorphism is associated with circulating C-reactive protein (The Ludwigshafen Risk and Cardiovascular Health Study). Eur. Heart J. 25, 2109-2119, 2004

185. Simeoni, E., Winkelmann, B.R., Hoffmann, M.M., Fleury, S., Ruiz, J., Kappenberger, L., März, W., Vassalli, G.: Association of RANTES G-403A gene polymorphism with increased risk of coronary arteriosclerosis. Eur. Heart J. 25, 1438-1446, 2004

186. Simeoni, E., Hoffmann, M.M., Winkelmann, B.R., Ruiz, J., Fleury, S., Böhm, B.O., März, W., Vassalli, G.: Association between the A-2518G polymorphism in the monocyte chemoattractant protein-1 gene and insulin resistance and Type 2 diabetes mellitus. Diabetologia 47, 1574-1580, 2004

187. Vetter, S., Ruf, G., Regourd, E., März, W.: The use of atorvastatin treatment in usual care environments: pooled analysis of six prospective, observational studies in 90,535 patients. Int. J. Clin. Pharmacol. Ther. 42, 423-433, 2004

188. Wanner, C., Krane, V., März, W., Olschewski, M., Asmus, H.G., Krämer, W., Kühn, K.W., Kütemeyer, H., Mann, J.F., Ruf, G., Ritz, E.: Randomized Controlled Trial on the Efficacy and Safety of Atorvastatin in Patients with Type 2 Diabetes on Hemodialysis (4D Study): Demographic and Baseline Characteristics. Kidney Blood Press Res. 27, 259-266, 2004

189. März, W., Böhm, B.O., Winkelmann, B.R., Hoffmann, M.M.: The PlA1/A2 polymorphism of platelet glycoprotein IIIa is not associated with the risk of type 2 diabetes. The Ludwigshafen Risk and Cardiovascular Health Study. Diabetologia 47,1969-1973, 2004

190. Renner, W., Grammer, T., Hoffmann, M.M., Nauck, M.S., Winkelmann, B.R., Böhm B.O., März, W.: Association analysis of the polymorphism T1128C in the signal peptide of neuropeptide Y in a Swedish hypertensive population. J. Hypertens. 22, 2398-2399, 2004 (Letter)

191. Weger, M., Steinbrugger, I., Haas, A., März, W., El-Shabrawi, Y., Weger, W., Schmut, O., Renner, W.: Role of the interleukin-6 – 174 G>C gene polymorphism in retinal artery occlusion. Stroke 36, 249-252, 2005

192. Renner, W., Nauck, M., Winkelmann, B.R., Hoffmann, M.M., Scharnagl, H., Böhm, B.O., März, W.: Association of angiotensinogen haplotypes with angiotensinogen levels but not with blood pressure or coronary artery disease: the Ludwigshafen Risk and Cardiovascular Health Study. J. Mol. Med. 83, 235-239, 2005

193. Winkler, K., Winkelmann, B.R., Scharnagl, H., Hoffmann, M.M., Grawitz, A.B., Nauck, M., Böhm, B.O., März, W.: Platelet-activating factor acetylhydrolase activity indicates angiographic coronary artery disease independently of systemic inflammation and other risk factors. The Ludwigshafen Risk and Cardiovascular Health Study. Circulation 111, 980-987, 2005

194. Winkler, K., Hoffmann, M.M., Busse-Grawitz, A., Nauck, M., Winkelmann, B.R., Scharnagl, H., März, W., Böhm, B.O.: Response to Ewa Ninio: Letter regarding article by Winkler et al., Circulation 2005; 111: 980-987. Circulation 112, e108-e109, 2005

195. Wittchen, H.-U., Glaesmer, H., März, W., Stalla, G., Lehnert, H., Zeiher, A.M., Silber, S., Koch, U., Böhler, S., Pittrow, D., Ruf, G.: Cardiovascular risk factors in primary care: methods and baseline prevalence rates – DETECT program. Curr. Med. Res. Opin. 21, 619-629, 2005

196. Landmesser, U., Bahlmann, F., Müller, M., Spiekermann, S., Kirchhoff, N., Schulz, S., Manes, C., Fischer, D., de Groot, K., Fliser, D., Fauler, G., März, W., Drexler, H.: Simvastatin versus Ezetimibe: Pleiotropic and lipid-lowering effects on endothelial function in humans. Circulation 111, 2356-2363, 2005

197. Löw, M., Hoffmann, M.M., Hahmann, H., März, W., Rothenbacher, D., Brenner, H.: Smoking, apolipoprotein E genotype, and early onset of coronary heart disease. Eur. J. Cardiovasc. Prev. Rehabil. 12, 268-270, 2005

198. Rothenbacher, D., Brenner, H., März, W., Koenig, W.: Adiponectin, risk of coronary heart disease and correlations with cardiovascular risk markers. Eur. Heart J. 26, 1640-1646, 2005

199. Zotz, R.B., Winkelmann, B.R., Müller, C., Böhm, B.O., März, W., Scharf, R.E.: Association of polymorphisms of platelet membrane integrins alphaIIbbeta3 (HPA-1b/PlA2) and alpha2beta1 (alpha2807TT) with premature myocardial infarction. J. Thromb. Haemost. 3, 1522-1529, 2005

200. Wanner, C., Krane, V., März, W., Olschewski, M., Mann, J.F., Ruf, G., Ritz, E.; German Diabetes and Dialysis Study Investigators. Atorvastatin in patients with type 2 diabetes mellitus undergoing hemodialysis. N. Engl. J. Med. 353, 238-248, 2005

201. Böhm, B.O., Claudi-Böhm, S., Yildirim, S., Haenle, M.M., Hay, B., Mason, R.A., Steinbach, G., Koenig, W., Kern, P., März, W., Kratzer, W.: Prevalence of the metabolic syndrome in southwest Germany. Scand. J. Clin. Lab. Invest. 65 (Suppl. 240), 122-128, 2005

202. Khuseyinova, N., Imhof, A., Rothenbacher, D., Trischler, G., Kuelb, S., Scharnagl, H., März, W., Brenner, H., Koenig, W.: Association between Lp-PLA(2) and coronary artery disease: Focus on its relationship with lipoproteins and markers of inflammation and hemostasis. Atherosclerosis 182, 181-188, 2005

203. Pilz, S., Horejsi, R., Moller, R., Almer, G., Scharnagl, H., Stojakovic, T., Dimitrova, R., Weihrauch, G., Borkenstein, M., März, W., Schauenstein, K., Mangge, H.: Early atherosclerosis in obese juveniles is associated with low serum levels of adiponectin. J. Clin. Endocrinol. Metab. 90, 4792-4796, 2005

204. Meinitzer, A., Zink, M., März, W., Baumgartner, A., Halwachs-Baumann, G.: Midazolam and its metabolites in brain death diagnosis. Int. J. Clin. Pharmacol. Ther. 43, 517-526, 2005

205. Pieper, L., Wittchen, H.-U., Glaesmer, H., Klotsche, J., März, W., Stalla, G., Lehnert, H., Zeiher, A.M., Silber, S., Koch, U., Böhler, S., Pittrow, D., Ruf, G.: Kardiovaskuläre Hochrisikokonstellationen in der primärärztlichen Versorgung: DETECT Studie 2003. Bundesgesundheitsblatt 48, 1374-1382, 2005

206. Pilz, S., März, W., Weihrauch, G., Sargsyan, K., Almer, G., Nauck, M., Böhm B.O., Winkelmann, B.R., Mangge, H.: Adiponectin serum concentrations in men with coronary artery disease: The LUdwigshafen RIsk in Cardiovascular Health (LURIC) study. Clin. Chim. Acta 364, 251-255, 2006

207. Pilz, S., Scharnagl, H., Tiran, B., Seelhorst, U., Wellnitz, B., Böhm, B.O., Schäfer, J.R., März, W.: Free fatty acids are independently associated with all-cause and cardiovascular mortality in subjects with coronary artery disease. J. Clin. Endocrionol. Metab. 91, 2542–2547, 2006

208. Schneider, H.J., Saller, B., Klotsche, J., März, W., Erwa, W., Wittchen, H.-U., Stalla, G.K.: Opposite associations of age-dependent insulin-like growth factor-1 standard deviation scores with nutritional state in normal weight and obese subjects. Eur. J. Endocrinol. 154, 699-706, 2006

209. Scharnagl, H., Vogel, M., Abletshauser, C., Freisinger, F., Stojakovic, T., März, W.: Efficacy and Safety of Fluvastatin-Extended Release in Hypercholesterolemic Patients: Morning Administration Is Equivalent to Evening Administration. Cardiology 106, 241-248, 2006

210. Löw, M., Hoffmann, M.M., Hahmann, H., März, W., Brenner, H., Rothenbacher, D.: Genotype combinations of plasminogen activator inhibitor-1 and angiotensin-converting enzyme genes and risk for early onset of coronary heart disease. Eur. J. Cardiovasc. Prev. Rehabil. 13, 449-456, 2006

211. Stettin, M., Halwachs-Baumann, G., Genser, B., Frühwirth, F., März, W. Khoschsorur, G.A.: Determination of cyclosporine A in whole blood: Comparison of a chromatographic method with three different immunological methods. Talanta 69, 1100-1105, 2006

212. Meisner, F., Walcher, D., Gizard, F., Kapfer, X., Huber, R., Noak, A., Sunder-Plassmann, L., Bach, H., Haug, C., Bachem, M., Stojakovic, T., März, W., Hombach, V., Koenig, W., Staels, B., Marx, N.: Effect of rosiglitazone treatment on plaque inflammation and collagen content in nondiabetic patients. Data from a randomized, placebo-controlled trial. Arterioscler. Thromb. Vasc. Biol. 2006, 26, 845-850

213. Meinitzer, A., März, W.M., Mangge, H., Halwachs-Baumann. G.: More reliable brain death diagnosis with chromatographic analysis of midazolam, diazepam, thiopentone and active metabolites. J. Anal. Toxicol. 30, 196-201, 2006

214. Trummer, O., Köppel, H., Wascher, T.C., Grünbacher, G., Gutjahr, M., Stanger, O., Ramschak-Schwarzer, S., Böhm, B.O., Winkelmann, B.R., März, W., Renner, W.: The serotonin transporter gene polymorphism is not associated with smoking behavior. Pharmacogenomics J. 6, 397-400, 2006

215. Genser, B., März, W.: Low density lipoprotein cholesterol, statins and cardiovascular events: a meta-analysis. Clin. Res. Cardiol. 95, 393-404, 2006

216. Grammer, T.B., Renner, W., von Karger, S., Böhm, B.O., Winkelmann B.R., März, W.: The angiotensin-I converting enzyme I/D polymorphism is not associated with type 2 diabetes in individuals undergoing coronary angiography. (The Ludwigshafen Risk and Cardiovascular Health Study). Mol. Genet. Metab. 88, 378-388, 2006

217. Yazdani-Biuki, B., Brickmann, K., Wohlfahrt, K., Mueller, T., März, W., Renner, W., Gutjahr, M., Langsenlehner, U., Krippl, P., Wascher, T.C., Paulweber, B., Graninger, W., Brezinschek, H.P.: The MHC2TA -168A>G gene polymorphism is not associated with rheumatoid arthritis in Austrian patients. Arthritis Res. Ther. 8, R97, 2006

218. Pittrow, D., Stalla, G.K., Zeiher, A.M., Silber, S., März, W., Pieper, L., Klotsche, J., Glaesmer, H., Ruf, G., Schneider, J., Lehnert, H., Böhler, S., Koch, U., Wittchen, H.U.: Prävalenz, medikamentöse Behandlung und Einstellung des Diabetes mellitus in der Hausarztpraxis. Med. Klin. 101, 635-644, 2006

219. Pilz, S., Mangge, H., Wellnitz, B., Seelhorst, U., Winkelmann, B.R., Tiran, B., Böhm, B.O., März, W.: Adiponectin and mortality in patients undergoing coronary angiography. J. Clin. Endocrinol. Metab. 91, 4277-4286, 2006

220. Ruef, J., März, W., Winkelmann, B.R.: Markers for endothelial dysfunction, but not markers for oxidative stress correlate with classical risk factors and the severity of coronary artery disease. (A subgroup analysis from the Ludwigshafen Risk and Cardiovascular Health Study). Scand. Cardiovasc. J. 40, 274-279, 2006

221. Putz-Bankuti, C., Datz, C., März, W., Lackner, C., Stauber, R.E., Trauner, M., Toplak, H., Stojakovic, T., Krejs, G.J.: Clinical-Pathological Conference Series from the Medical University of Graz : Case No. 131: Elevated transaminases in a 30-year-old male. Wien Klin. Wochenschr. 118, 769-775, 2006

222. Böhler, S., Scharnagl, H., Freisinger, F., Stojakovic, T., Glaesmer, H., Klotsche, J., Pieper, L., Pittrow, D., Kirch, W., Schneider, H., Stalla, G.K., Lehnert, H., Zeiher, A.M., Silber, S., Koch, U., Ruf, G., März, W., Wittchen, H.U. Unmet needs in the diagnosis and treatment of dyslipidemia in the primary care setting in Germany. Atherosclerosis 190, 397-407, 2007

223. Fauler, G., Abletshauser, C., Erwa, W., Löser, R., Witschital, K., März, W. Time-of-intake (morning versus evening) of extended-release fluvastatin in hyperlipemic patients is without influence on the pharmacodynamics (mevalonic acid excretion) and pharmacokinetics. Int. J. Clin. Pharmacol. Ther. 45, 328-334, 2007

224. Grünbacher, G., Weger, W., Marx-Neuhold, E., Pilger, E., Köppel, H., Wascher, T., März, W., Renner W. The fibrinogen gamma (FGG) 10034C>T polymorphism is associated with venous thrombosis. Thromb. Res. 121, 33-36, 2007

225. Hoffmann, M.M., Bugert, P., Seelhorst, U., Wellnitz, B., Winkelmann, B.R., Böhm, B.O., März, W. The -50G>T polymorphism in the promoter of the CYP2J2 gene in coronary heart disease: the Ludwigshafen Risk and Cardiovascular Health study. Clin. Chem. 53, 539-540, 2007

226. Krane, V., Krieter, D.H., Olschewski, M., März, W., Mann, J.F., Ritz, E., Wanner, C. Dialyzer membrane characteristics and outcome of patients with type 2 diabetes on maintenance hemodialysis. Am. J. Kidney Dis. 49, 267-275, 2007

227. März, W., Seelhorst, U., Wellnitz, B., Tiran, B., Obermayer-Pietsch, B., Renner, W., Böhm, B.O., Ritz, E., Hoffmann, M.M. Alanine to serine polymorphism at position 986 of the calcium-sensing receptor associated with coronary heart disease, myocardial infarction, all-cause, and cardiovascular mortality. J. Clin. Endocrinol. Metab. 92, 2363-2369, 2007

228. März, W., Tiran, B., Seelhorst, U., Wellnitz, B., Bauersachs, J., Winkelmann, B.R., Böhm, B.O. N-terminal pro-B-type natriuretic peptide predicts total and cardiovascular mortality in individuals with or without stable coronary artery disease: the Ludwigshafen Risk and Cardiovascular Health Study. Clin. Chem. 53, 1075-1083, 2007

229. Mayer, C., Gruber, H.J., Landl, E.M., Pailer, S., Scharnagl, H., Truschnig-Wilders, M., März, W. Rosuvastatin reduces interleukin-6-induced expression of C-reactive protein in human hepatocytes in a STAT3- and C/EBP-dependent fashion. Int. J. Clin. Pharmacol. Ther. 45, 319-327, 2007

230. Meinitzer, A., Puchinger, M., Winklhofer-Roob, B.M., Rock, E., Ribalta, J., Roob, J.M., Sundl, I., Halwachs-Baumann, G., März, W. Reference values for plasma concentrations of asymmetrical dimethylarginine (ADMA) and other arginine metabolites in men after validation of a chromatographic method. Clin. Chim. Acta 384, 141-148, 2007

231. Meinitzer, A., Seelhorst, U., Wellnitz, B., Halwachs-Baumann, G., Böhm, B.O., Winkelmann, B.R., März, W. Asymmetrical dimethylarginine independently predicts total and cardiovascular mortality in individuals with angiographic coronary artery disease (the Ludwigshafen Risk and Cardiovascular Health study). Clin. Chem. 53, 273-283, 2007

232. Pilz, S., Scharnagl, H., Tiran, B., Wellnitz, B., Seelhorst, U., Böhm, B.O., März, W. Elevated plasma free fatty acids predict sudden cardiac death: a 6.85-year follow-up of 3315 patients after coronary angiography. Eur. Heart J. 28, 2763-2769, 2007

233. Pilz, S., Weihrauch, G., Seelhorst, U., Wellnitz, B., Winkelmann, B.R., Böhm, B.O., März W. Implications of resistin plasma levels in subjects undergoing coronary angiography. Clin. Endocrinol. 66, 380-386, 2007

234. Renner, W., Hoffmann, M.M., Grünbacher, G., Winkelmann, B.R., Böhm, B.O., März, W. G-protein beta3 subunit (GNB3) gene polymorphisms and cardiovascular disease: the Ludwigshafen Risk and Cardiovascular Health (LURIC) study. Atherosclerosis 192, 108-112, 2007

235. Schäfer, C., Parlesak, A., Eckoldt, J., Bode, C., Bode, J.C., März, W., Winkler, K. Beyond HDL-cholesterol increase: phospholipid enrichment and shift from HDL3 to HDL2 in alcohol consumers. J. Lipid Res. 48, 1550-1558, 2007

236. Scharnagl, H., Stojakovic, T., Winkler, K., Rosinger, S., März, W., Böhm, B.O. The HMG-CoA reductase inhibitor cerivastatin lowers advanced glycation end products in patients with type 2 diabetes. Exp. Clin. Endocrinol. Diabetes 115, 372-375, 2007

237. Schneider, H.J., Glaesmer, H., Klotsche, J., Böhler, S., Lehnert, H., Zeiher, A.M., März, W., Pittrow, D., Stalla, G.K., Wittchen, H.U. Accuracy of anthropometric indicators of obesity to predict cardiovascular risk. J Clin. Endocrinol. Metab. 92, 589-594, 2007

238. Schwab, K.O., Dörfer, J., Krebs, A., Krebs, K., Schorb, E., Hallermann, K., Superti-Furga, A., Zieger, B., März, W., Schmidt-Trucksass, A., Winkler, K. Early atherosclerosis in childhood type 1 diabetes: role of raised systolic blood pressure in the absence of dyslipidaemia. Eur. J. Pediatrics 166, 541-548, 2007

239. Stojakovic, T., Putz-Bankuti, C., Fauler, G., Scharnagl, H., Wagner, M., Stadlbauer, V., Gurakuqi, G., Stauber, R.E., März, W., Trauner. M. Atorvastatin in patients with primary biliary cirrhosis and incomplete biochemical response to ursodeoxycholic acid. Hepatology 46, 776-784, 2007

240. Stojakovic, T., Scharnagl, H., März, W., Winkelmann, B.R., Böhm, B.O., Schmut, O. Low density lipoprotein triglycerides and lipoprotein(a) are risk factors for retinal vascular occlusion. Clin. Chim Acta 382, 77-81, 2007

241. Wegscheider, B.J., Weger, M., Renner, W., Steinbrugger, I., März, W., Mossbock, G., Temmel, W., El-Shabrawi, Y., Schmut, O., Jahrbacher, R., Haas, A. Association of complement factor H Y402H gene polymorphism with different subtypes of exudative age-related macular degeneration. Ophthalmology 114, 738-742, 2007

242. Winkler, K., Hoffmann, M.M., Winkelmann, B.R., Friedrich, I., Schafer, G., Seelhorst, U., Wellnitz, B., Wieland, H., Böhm, B.O., März, W. Lipoprotein-associated phospholipase A2 predicts 5-year cardiac mortality independently of established risk factors and adds prognostic information in patients with low and medium high-sensitivity C-reactive protein (the Ludwigshafen Risk and Cardiovascular Health study). Clin. Chem. 53, 1440-1447, 2007

243. Bach, J., Endler, G., Winkelmann, B.R., Böhm, B.O., März, W., Mannhalter, C., Hellstern, P. Coagulation factor XII (FXII) activity, activated FXII, distribution of FXII C46T gene polymorphism and coronary risk. J Thromb. Haemost. 6, 291-296, 2008

244. Dobnig, H., Pilz, S., Scharnagl, H., Renner, W., Seelhorst, U., Wellnitz, B., Kinkeldei, J., Böhm, B.O., Weihrauch, G., März, W. Independent association of low serum 25-hydroxyvitamin D and 1,25-dihydroxyvitamin D levels with all-cause and cardiovascular mortality. Arch. Intern. Med. 168, 1340-1349, 2008

245. Hoffmann, M.M., Pilz, S., Weihrauch, G., Seelhorst, U., Wellnitz, B., Winkelmann, B.R., Böhm, B.O., März, W. Effect of the resistin -420C > G polymorphism on cardiovascular disease and mortality. Clin. Endocrinol. 69, 344-345, 2008

246. Pilz, S., Dobnig, H., Fischer, J.E., Wellnitz, B., Seelhorst, U., Böhm, B.O., März, W. Low vitamin D levels predict stroke in patients referred to coronary angiography. Stroke 39, 2611-2613, 2008

247. Pilz, S., Dobnig, H., Winklhofer-Roob, B., Riedmuller, G., Fischer, J.E., Seelhorst, U., Wellnitz, B., Böhm, B.O., März, W. Low serum levels of 25-hydroxyvitamin D predict fatal cancer in patients referred to coronary angiography. Cancer Epidemiol. Biomarkers Prev. 17, 1228-1233, 2008

248. Siekmeier, R., Grammer, T. and März, W., Roles of oxidants, nitric oxide, and asymmetric dimethylarginine in endothelial function, J Cardiovasc Pharmacol Ther, 13, 279-297, 2008

249. Genser, B., Grammer, T. B., Stojakovic, T., Siekmeier, R. and März, W., Effect of HMG CoA reductase inhibitors on low-density lipoprotein cholesterol and C-reactive protein: systematic review and meta-analysis, Int J Clin Pharmacol Ther, 46, 497-510, 2008

250. Schneider, H.J., Klotsche, J., Saller, B., Böhler, S., Sievers, C., Pittrow, D., Ruf, G., März, W., Erwa, W., Zeiher, A.M., Silber, S., Lehnert, H., Wittchen, H.U., Stalla, G.K. Associations of age-dependent IGF-I SDS with cardiovascular diseases and risk conditions: cross-sectional study in 6773 primary care patients. Eur. J. Endocrinol. 158, 153-161, 2008

251. Wilders-Truschnig, M., Mangge, H., Lieners, C., Gruber ,H., Mayer, C., März, W. IgG antibodies against food antigens are correlated with inflammation and intima media thickness in obese juveniles. Exp. Clin. Endocrinol. Diabetes 116, 241-245, 2008

252. Winkler, K., Hoffmann, M.M., Seelhorst, U., Wellnitz, B., Böhm, B.O., Winkelmann, B.R., März, W., Scharnagl H. Apolipoprotein A-II is a negative risk indicator for cardiovascular and total mortality: findings from the Ludwigshafen Risk and Cardiovascular Health Study. Clin. Chem. 54, 1405-1406, 2008

253. Krane, V., Winkler, K., Drechsler, C., Lilienthal, J., März, W., Wanner C. Effect of atorvastatin on inflammation and outcome in patients with type 2 diabetes mellitus on hemodialysis. Kidney Int. 74, 1461-1467, 2008

254. Silber, S., Jarre, F., Pittrow, D., Klotsche, J., Pieper, L., Zeiher, A. M., Wittchen, H. U., [Cardiovascular risk assessment by primary-care physicians in Germany and its lack of agreement with the Established Risk Scores (DETECT)], Med Klin (Munich), 103, 638-645, 2008

255. Meinitzer, A., Kalcher, K., Gartner, G., Halwachs-Baumann, G., März, W., Stettin, M. Drugs and brain death diagnostics: determination of drugs capable of inducing EEG zero line. Clin Chem Lab Med 46, 1732-1738, 2008

256. Böhm, B.O., Möller, P., Hogel, J., Winkelmann, B.R., Renner, W., Rosinger, S., Seelhorst, U., Wellnitz, B., März, W., Melzner, J., Brüderlein, S. Lymphocytes of type 2 diabetic women carry a high load of stable chromosomal aberrations: A novel risk factor for disease-related early death. Diabetes 57, 2950-2957, 2008

257. Gruber, H.J., Mayer, C., Meinitzer, A., Almer, G., Horejsi, R., Moller, R., Pilz, S., März, W., Gasser, R., Truschnig-Wilders, M., Mangge, H. Asymmetric Dimethylarginine (ADMA) is tightly correlated with growth in juveniles without correlations to obesity related disorders. Exp. Clin. Endocrinol. Diabetes 116, 520-524, 2008

258. Pilz, S., März, W., Wellnitz, B., Seelhorst, U., Fahrleitner-Pammer, A., Dimai, H.P., Böhm, B.O., Dobnig, H. Association of vitamin D deficiency with heart failure and sudden cardiac death in a large cross-sectional study of patients referred for coronary angiography. J. Clin. Endocrinol. Metab. 93, 3927-3935, 2008

259. Winkler, K., Wanner, C., Drechsler, C., Lilienthal, J., März, W., Krane, V. Change in N-terminal-pro-B-type-natriuretic-peptide and the risk of sudden death, stroke, myocardial infarction, and all-cause mortality in diabetic dialysis patients. Eur. Heart J. 29, 2092-2099, 2008.

260. Murr, C., Winklhofer-Roob, B.M., Schroecksnadel, K., Maritschnegg, M., Mangge, H., Bohm, B. O., Winkelmann, B. R., März, W. Fuchs, D. Inverse association between serum concentrations of neopterin and antioxidants in patients with and without angiographic coronary artery disease. Atherosclerosis 202, 543-549, 2009

261. Silbernagel, G., Fauler, G., Renner, W., Landl, E. M., Hoffmann, M. M., Winkelmann, B.R. Böhm, B.O., März, W. The relationships of cholesterol metabolism and plasma plant sterols with the severity of coronary artery disease. J. Lipid Res. 50, 334-341, 2009

262. Pilz, S., Dobnig, H., Winklhofer-Roob, B. M., Renner, W., Seelhorst, U., Wellnitz, B., Böhm, B.O., März, W. Low serum zinc concentrations predict mortality in patients referred to coronary angiography. Br. J. Nutr 101, 1534-1540, 2009

263. Hoffmann, M.M., Winkler, K., Renner, W., Winkelmann, B.R., Seelhorst, U., Wellnitz, U., Böhm, B.O. März, W. Genetic variants and haplotypes of lipoprotein associated phospholipase A2 and their influence on cardiovascular disease (The Ludwigshafen Risk and Cardiovascular Health Study). J Thromb Haemost 7, 41-48, 2009

264. Grammer, T. B., März, W., Renner, W., Böhm, B.O., Hoffmann, M.M. C-reactive protein genotypes associated with circulating C-reactive protein but not with angiographic coronary artery disease: the LURIC study. Eur. Heart J. 30, 170-182, 2009

265. Silbernagel, G., Stefan, N., Hoffmann, M.M., Machicao-Arano, F., Machann, J., Schick, F., Winkelmann, B.R., Böhm, B.O., Häring, H.U., Fritsche, A., März W. The L162V polymorphism of the peroxisome proliferator activated receptor alpha gene (PPARA) is not associated with type 2 diabetes, BMI or body fat composition. Exp. Clin. Endocrinol. Diabetes 117,113-118, 2009

266. Stojakovic, T., Claudel, T., Putz-Bankuti, C., Fauler, G., Scharnagl, H., Wagner, M., Sourij, H., Stauber, R. E., Winkler, K., März, W., Wascher, T. C., Trauner, M. Low-dose atorvastatin improves dyslipidemia and vascular function in patients with primary biliary cirrhosis after one year of treatment. Atherosclerosis 209, 178-183, 2010

267. Matzhold, E. M., Trummer, O., Grünbacher, G., Zulus, B., Böhm, B. O., März, W., Renner, W. Association of polymorphisms in the chemokine receptor CX3CR1 gene with coronary artery disease. Cytokine 47, 224-227, 2009

268. Krane, V., Winkler, K., Drechsler, C., Lilienthal, J., März, W., Wanner, C. Association of LDL cholesterol and inflammation with cardiovascular events and mortality in hemodialysis patients with type 2 diabetes mellitus. Am. J. Kidney Dis. 54, 902-911, 2009

269. Abedini, S., Holme, I., März, W., Weihrauch, G., Fellstrom, B., Jardine, A., Cole, E., Maes, B., Neumayer, H. H., Gronhagen-Riska, C., Ambuhl, P., Holdaas, H. Inflammation in renal transplantation. Clin. J. Am. Soc. Nephrol. 4, 1246-1254, 2009

270. Murr, C., Meinitzer, A., Grammer, T., Schroecksnadel, K., Böhm, B. O., März, W., Fuchs, D. Association between asymmetric dimethylarginine and neopterin in patients with and without angiographic coronary artery disease. Scand J Immunol 70, 63-67, 2009

271. Karakas, M., Hoffmann, M. M., Vollmert, C., Rothenbacher, D., Meisinger, C., Winkelmann, B., Khuseyinova, N., Bohm, B. O., Illig, T., März, W., Koenig, W. Genetic variation in Fc gamma receptor IIa and risk of coronary heart disease: negative results from two large independent populations. BMC Med. Genet 10, 46, 2009

272. Drechsler, C., Krane, V., Grootendorst, D. C., Ritz, E., Winkler, K., März, W., Dekker, F., Wanner, C. The association between parathyroid hormone and mortality in dialysis patients is modified by wasting. Nephrol. Dial. Transplant 24, 3151-3157, 2009

273. Lüblinghoff N, Winkler K, Winkelmann BR, Seelhorst U, Wellnitz B, Böhm BO, März W, Hoffmann MM. Genetic variants of the promoter of the heme oxygenase-1 gene and their influence on cardiovascular disease (the Ludwigshafen Risk and Cardiovascular Health study). BMC Med Genet 10, 36, 2009

274. Erdmann, J., Grosshennig, A., Braund, P. S., Konig, I. R., Hengstenberg, C., Hall, A. S., Linsel-Nitschke, P., Kathiresan, S., Wright, B., Tregouet, D. A., Cambien, F., Bruse, P., Aherrahrou, Z., Wagner, A. K., Stark, K., Schwartz, S. M., Salomaa, V., Elosua, R., Melander, O., Voight, B. F., O'Donnell, C. J., Peltonen, L., Siscovick, D. S., Altshuler, D., Merlini, P. A., Peyvandi, F., Bernardinelli, L., Ardissino, D., Schillert, A., Blankenberg, S., Zeller, T., Wild, P., Schwarz, D. F., Tiret, L., Perret, C., Schreiber, S., El Mokhtari, N. E., Schafer, A., März, W., Renner, W., Bugert, P., Kluter, H., Schrezenmeir, J., Rubin, D., Ball, S. G., Balmforth, A. J., Wichmann, H. E., Meitinger, T., Fischer, M., Meisinger, C., Baumert, J., Peters, A., Ouwehand, W. H., Deloukas, P., Thompson, J. R., Ziegler, A., Samani, N. J., Schunkert, H., New susceptibility locus for coronary artery disease on chromosome 3q22.3. Nat. Genet. 41, 280-282, 2009

275. Samani, N. J., Deloukas, P., Erdmann, J., Hengstenberg, C., Kuulasmaa, K., McGinnis, R., Schunkert, H., Soranzo, N., Thompson, J., Tiret, L., Ziegler, A., Large scale association analysis of novel genetic loci for coronary artery disease. Arterioscler. Thromb. Vasc. Biol. 29, 774-780, 2009

276. Drechsler, C., Krane, V., Ritz, E., März, W., Wanner, C., Glycemic control and cardiovascular events in diabetic hemodialysis patients. Circulation 120, 2421-2428, 2009

277. Buschmann, E. E., Utz, W., Pagonas, N., Schulz-Menger, J., Busjahn, A., Monti, J., März, W., le Noble, F., Thierfelder, L., Dietz, R., Klauss, V., Gross, M. and Buschmann, I. R., Improvement of fractional flow reserve and collateral flow by treatment with external counterpulsation (Art.Net.-2 Trial), Eur J Clin Invest, 39, 866-875, 2009

278. Grammer TB, Fuchs D, Böhm BO, Winkelmann BR, März W. Neopterin as a predictor of total and cardiovascular mortality in individuals undergoing angiography in the Ludwigshafen Risk and Cardiovascular Health study. Clin Chem 55, 1135-1146, 2009

279. Grammer, T.B., Renner, W., Hoffmann, M.M., Kleber, M., Winkelhofer-Roob, B.M., Böhm, B.O., März, W. SOD3 R231G polymorphism associated with coronary artery disease and myocardial infarction. The Ludwigshafen Risk and Cardiovascular Health (LURIC) study. Free Radic Res 43, 677-684, 2009

280. Grandi, N. C., Breitling, L. P., Vossen, C. Y., Hahmann, H., Wusten, B., März, W., Rothenbacher, D., Brenner, H. Serum vitamin D and risk of secondary cardiovascular disease events in patients with stable coronary heart disease, Am. Heart J. 159, 1044-1051, 2010

281. Stojakovic, T., Scharnagl, H., Trauner, M., Pieske, B., Wellnitz, B., Seelhorst, U., Schilling, D., Winkelmann, B. R., Böhm, B. O., März, W. Serum gamma-glutamyl transferase and mortality in persons undergoing coronary angiography-The Ludwigshafen Risk and Cardiovascular Health Study, Atherosclerosis 208, 564-571, 2010

282. Winkler, K., Hoffmann, M. M., Krane, V., März, W., Drechsler, C., Wanner, C., Apolipoprotein E genotype predicts cardiovascular endpoints in dialysis patients with type 2 diabetes mellitus, Atherosclerosis, 208, 197-202, 2010

283. Tomaschitz, A., Pilz, S., Ritz, E., Grammer, T., Drechsler, C., Böhm, B. O., März, W. Independent association between 1,25-dihydroxyvitamin D, 25-hydroxyvitamin D and the renin-angiotensin system The Ludwigshafen Risk and Cardiovascular Health (LURIC) study, Clin. Chim. Acta 411, 1354-1360, 2010

284. Casas, J. P., Ninio, E., Panayiotou, A., Palmen, J., Cooper, J. A., Ricketts, S. L., Sofat, R., Nicolaides, A. N., Corsetti, J. P., Fowkes, F. G., Tzoulaki, I., Kumari, M., Brunner, E. J., Kivimaki, M., Marmot, M. G., Hoffmann, M. M., Winkler, K., März, W., Ye, S., Stirnadel, H. A., Khaw, K. T., Humphries, S. E., Sandhu, M. S., Hingorani, A. D., Talmud, P. J. PLA2G7 genotype, lipoprotein-associated phospholipase A2 activity, and coronary heart disease risk in 10 494 cases and 15 624 controls of European Ancestry. Circulation 121, 2284-2293, 2010

285. Collaborator für: Sarwar, N., Sandhu, M. S., Ricketts, S. L., Butterworth, A. S., Di Angelantonio, E., Boekholdt, S. M., Ouwehand, W., Watkins, H., Samani, N. J., Saleheen, D., Lawlor, D., Reilly, M. P., Hingorani, A. D., Talmud, P. J., Danesh, J., Triglyceride-mediated pathways and coronary disease: collaborative analysis of 101 studies, Lancet 375, 1634-1639, 2010

286. Pilz, S., Tomaschitz, A., Drechsler, C., Ritz, E., Böhm, B. O., Grammer, T. B., März, W. Parathyroid hormone level is associated with mortality and cardiovascular events in patients undergoing coronary angiography. Eur. Heart J. 31, 1591-1598, 2010.

287. Collaborator für: Thompson, A., Gao, P., Orfei, L., Watson, S., Di Angelantonio, E., Kaptoge, S., Ballantyne, C., Cannon, C. P., Criqui, M., Cushman, M., Hofman, A., Packard, C., Thompson, S. G., Collins, R., Danesh, J., Lipoprotein-associated phospholipase A(2) and risk of coronary disease, stroke, and mortality: collaborative analysis of 32 prospective studies. Lancet 375, 1536-1544, 2010

288. Kozian, D. H., Barthel, A., Cousin, E., Brunnhofer, R., Anderka, O., März, W., Bohm, B., Winkelmann, B., Bornstein, S. R., Schmoll, D. Glucokinase-activating GCKR polymorphisms increase plasma levels of triglycerides and free fatty acids, but do not elevate cardiovascular risk in the Ludwigshafen Risk and Cardiovascular Health Study. Horm. Metab. Res. 42, 502-506, 2010

289. Silbernagel, G., Fauler, G., Hoffmann, M. M., Lutjohann, D., Winkelmann, B. R., Böhm, B. O., März, W. The associations of cholesterol metabolism and plasma plant sterols with all-cause- and cardiovascular mortality. J. Lipid Res. 51, 2384-2393, 2010

290. Schroecksnadel, K., Grammer, T. B., Böhm, B. O., März, W., Fuchs, D. Total homocysteine in patients with angiographic coronary artery disease correlates with inflammation markers. Thromb. Haemost. 103, 926-935, 2010

291. Kozian, D. H., Lorenz, M., März, W., Cousin, E., Mace, S., Deleuze, J. F., Association between the Thr325Ile polymorphism of the thrombin-activatable fibrinolysis inhibitor and stroke in the Ludwigshafen Risk and Cardiovascular Health Study. Thromb. Haemost. 103, 976-983, 2010

292. Tomaschitz, A., Pilz, S., Ritz, E., Meinitzer, A., Böhm, B. O., März, W. Plasma aldosterone levels are associated with increased cardiovascular mortality: the Ludwigshafen Risk and Cardiovascular Health (LURIC) study. Eur. Heart J, 31, 1237-1247, 2010

293. Stojakovic, T., de Campo, A., Scharnagl, H., Sourij, H., Schmolzer, I., Wascher, T. C., März, W., Differential effects of fluvastatin alone or in combination with ezetimibe on lipoprotein subfractions in patients at high risk of coronary events. Eur. J. Clin. Invest. 40, 187-194, 2010

294. Ritsch, A., Scharnagl, H., Eller, P., Tancevski, I., Duwensee, K., Demetz, E., Sandhofer, A., Böhm, B. O., Winkelmann, B. R., Patsch, J. R., März, W. Cholesteryl ester transfer protein and mortality in patients undergoing coronary angiography: the Ludwigshafen Risk and Cardiovascular Health study. Circulation 121, 366-374, 2010

295. Kleber, M. E., Renner, W., Grammer, T. B., Linsel-Nitschke, P., Böhm, B. O., Winkelmann, B. R., Bugert, P., Hoffmann, M. M., März, W. Association of the single nucleotide polymorphism rs599839 in the vicinity of the sortilin 1 gene with LDL and triglyceride metabolism, coronary heart disease and myocardial infarction. The Ludwigshafen Risk and Cardiovascular Health Study. Atherosclerosis 209, 492-497, 2010

296. Abedini, S., Meinitzer, A., Holme, I., März, W., Weihrauch, G., Fellstrom, B., Jardine, A., Holdaas, H., Asymmetrical dimethylarginine is associated with renal and cardiovascular outcomes and all-cause mortality in renal transplant recipients. Kidney Int. 77, 44-50, 2010

297. Pilz, S., Obermayer-Pietsch, B., Verduijn, M., Tomaschitz, A., Krane, V., Espe, K., Dekker, F., Brandenburg, V., März, W., Ritz, E., Wanner, C. Vitamin D deficiency is associated with sudden cardiac death, combined cardiovascular events, and mortality in haemodialysis patients. Eur. Heart J. 31, 2253-61, 2010

298. Sievers, C., Klotsche, J., Pieper, L., Schneider, H. J., März, W., Wittchen, H. U., Stalla, G. K., Mantzoros, C. Low testosterone levels predict all-cause mortality and cardiovascular events in women: a prospective cohort study in German primary care patients. Eur. J. Endocrinol. 163, 699-708, 2010

299. Preuss M, König IR, Thompson JR, Erdmann J, Absher D, Assimes TL, Blankenberg S, Boerwinkle E, Chen L, Cupples LA, Hall AS, Halperin E, Hengstenberg C, Holm H, Laaksonen R, Li M, März W, McPherson R, Musunuru K, Nelson CP, Burnett MS, Epstein SE, O'Donnell CJ, Quertermous T, Rader DJ, Roberts R, Schillert A, Stefansson K, Stewart AF, Thorleifsson G, Thorsteinsdottir U, Voight BF, Wells GA, Ziegler A, Kathiresan S, Reilly MP, Samani NJ, Schunkert H. Design of the Coronary Artery Disease Genome-Wide Replication and Meta-Analysis (CARDIoGRAM) Study -- A Genome-Wide Association Meta-Analysis Involving More than 22,000 Cases and 60,000 Controls. Circ. Cardiovasc. Genet. 3, 475-483, 2010

300. Soranzo N, Sanna S, Wheeler E, Gieger C, Radke D, Dupuis J, Bouatia-Naji N, Langenberg C, Prokopenko I, Stolerman E, Sandhu MS, Heeney MM, Devaney JM, Reilly MP, Ricketts SL, Stewart AF, Voight BF, Willenborg C, Wright B, Altshuler D, Arking D, Balkau B, Barnes D, Boerwinkle E, Böhm B, Bonnefond A, Bonnycastle LL, Boomsma DI, Bornstein SR, Böttcher Y, Bumpstead S, Burnett-Miller MS, Campbell H, Cao A, Chambers J, Clark R, Collins FS, Coresh J, de Geus EJ, Dei M, Deloukas P, Döring A, Egan JM, Elosua R, Ferrucci L, Forouhi N, Fox CS, Franklin C, Franzosi MG, Gallina S, Goel A, Graessler J, Grallert H, Greinacher A, Hadley D, Hall A, Hamsten A; on behalf of Procardis Consortium, Hayward C, Heath S, Herder C, Homuth G, Hottenga JJ, Hunter-Merrill R, Illig T, Jackson AU, Jula A, Kleber M, Knouff CW, Kong A, Kooner J, Köttgen A, Kovacs P, Krohn K, Kühnel B, Kuusisto J, Laakso M, Lathrop M, Lecoeur C, Li M, Li M, Loos RJ, Luan J, Lyssenko V, Mägi R, Magnusson PK, Mälarstig A, Mangino M, Martínez-Larrad MT, März W, McArdle WL, McPherson R, Meisinger C, Meitinger T, Melander O, Mohlke KL, Mooser VE, Morken MA, Narisu N, Nathan DM, Nauck M, O'Donnell C, Oexle K, Olla N, Pankow JS, Payne F, Peden JF, Pedersen NL, Peltonen L, Perola M, Polasek O, Porcu E, Rader DJ, Rathmann W, Ripatti S, Rocheleau G, Roden M, Rudan I, Salomaa V, Saxena R, Schlessinger D, Schunkert H, Schwarz P, Seedorf U, Selvin E, Serrano-Ríos M, Shrader P, Silveira A, Siscovick D, Song K, Spector TD, Stefansson K, Steinthorsdottir V, Strachan DP, Strawbridge R, Stumvoll M, Surakka I, Swift AJ, Tanaka T, Teumer A, Thorleifsson G, Thorsteinsdottir U, Tönjes A, Usala G, Vitart V, Völzke H, Wallaschofski H, Waterworth DM, Watkins H, Wichmann HE, Wild SH, Willemsen G, Williams GH, Wilson JF, Winkelmann J, Wright AF; WTCCC, Zabena C, Zhao JH, Epstein SE, Erdmann J, Hakonarson HH, Kathiresan S, Khaw KT, Roberts R, Samani NJ, Fleming MD, Sladek R, Abecasis G, Boehnke M, Froguel P, Groop L, McCarthy MI, Kao WH, Florez JC, Uda M, Wareham NJ, Barroso I, Meigs JB.Common variants at ten genomic loci influence hemoglobin A1C levels via glycemic and non-glycemic pathways. Diabetes 59, 3229-3239, 2010

301. März, W., Meinitzer, A., Drechsler, C., Pilz, S. Krane, V., Kleber, M.E., Fischer, J., Winkelmann, B.R., Böhm, B.O., Ritz, E., Wanner, C. Homoarginine, cardiovascular risk, and mortality. Circulation 122, 967-75, 2010

302. Saleheen, D., Soranzo, N., Rasheed, A., Scharnagl, H., Gwiliam, R., Alexander, M., Inouye, M., Zaidi, M., Potter, S., Haycock, P., Bumpstead, S., Kaptoge, S., Angelantonio, E. D., Sarwar, N., Hunt, S. E., Sheikh, N., Shah, N., Samuel, M., Haider, S. R., Murtaza, M., Thompson, A., Gobin, R., Butterworth, A., Ahmad, U., Hakeem, A., Zaman, K. S., Kundi, A., Yaqoob, Z., Cheema, L. A., Qamar, N., Faruqui, A., Mallick, N. H., Azhar, M., Samad, A., Ishaq, M., Rasheed, S. Z., Jooma, R., Niazi, J. H., Gardezi, A. R., Memon, N. A., Ghaffar, A., Rehman, F. U., Hoffmann, M. M., Renner, W., Kleber, M., Grammer, T. B., Stephens, J., Attwood, A., Koch, K., Hussain, M., Kumar, K., Saleem, A., Daood, M. S., Gul, A. A., Abbas, S., Zafar, J., Shahid, F., Bhatti, S. M., Ali, S. S., Fahim, M., Sagoo, G., Bray, S., McGinnis, R., Dudbridge, F., Winkelmann, B. R., Bohm, B., Thompson, S., Ouwehand, W., März, W., Frossard, P., Danesh, J., Deloukas, P. Genetic determinants of major blood lipids in Pakistan is compared with Europeans. Circ. Cardiovasc. Genet. 3, 348-357, 2010

303. Wehr, E., Pilz, S., Böhm, B. O., März, W., Obermayer-Pietsch, B. Association of vitamin D status with serum androgen levels in men. Clin Endocrinol (Oxf) 73, 243-248, 2010

304. Tomaschitz, A., März, W., Pilz, S., Ritz, E., Scharnagl, H., Renner, W., Böhm, BO, Fahrleitner-Pammer A, Weihrauch G, Dobnig H. Aldosterone/renin ratio determines peripheral and central blood pressure values over a broad range. J Am Coll Cardiol. 55, 2171-2180, 2010

305. Drechsler, C., Pilz, S., Obermayer-Pietsch, B., Verduijn, M., Tomaschitz, A., Krane, V., Espe, K., Dekker, F., Brandenburg, V., März, W., Ritz, E., Wanner, C. Vitamin D deficiency is associated with sudden cardiac death, combined cardiovascular events, and mortality in haemodialysis patients. Eur. Heart J. 31, 2253-2261, 2010

306. Wehr, E., Pilz, S., Böhm, B.O., März, W., Grammer, T.B., Obermayer-Pietsch, B. Sex steroids and mortality in men referred for coronary angiography. Clin Endocrinol (Oxf) 73, 613-21, 2010

307. Collaborator für: Bakris, G., Vassalotti, J., Ritz, E., Wanner, C., Stergiou, G., Molitch, M., Nesto, R., Kaysen, G.A., Sowers, J.R.; CKD Consensus Working Group. National Kidney Foundation consensus conference on cardiovascular and kidney diseases and diabetes risk: an integrated therapeutic approach to reduce events. Kidney Int. 78, 726-736, 2010

308. Meinitzer, A., Kielstein, J.T., Pilz, S., Drechsler, C., Ritz, E., Böhm, B.O., Winkelmann, B.R., März, W. Symmetrical and asymmetrical dimethylarginine as predictors for mortality in patients referred for coronary angiography: The Ludwigshafen Risk and Cardiovascular Health Study. Clin Chem. 57, 112-121, 2010

309. Haschke-Becher, E., Kirchheiner, J., Trummer, O., Grünbacher, G., Kainz, A., Böhm, B.O., März, W., Renner W. Impact of CYP2C8 and 2C9 polymorphisms on coronary artery disease and myocardial infarction in the LURIC cohort. Pharmacogenomics 11, 1359-65, 2010

310. Schneider, H., Friedrich, N., Klotsche, J., Schipf, S., Nauck, M., Volzke, H., Sievers, C., Pieper, L., März, W. Wittchen, H.U., Stalla, G.K., Wallaschofski, H. Prediction of incident diabetes mellitus by baseline insulin-like growth factor-I levels. Eur. J. Endocrinol. 164, 223-229, 2010

311. Kleber, M.E., Grammer, T.B., Renner, W., März, W. Effect of the rs2259816 polymorphism in the HNF1A gene on circulating levels of c-reactive protein and coronary artery disease (the Ludwigshafen Risk and Cardiovascular Health Study). BMC Med. Genet. 11, 157, 2010

312. Marzi, C., Albrecht, E., Hysi, P.G., Lagou, V., Waldenberger, M., Tönjes, A., Prokopenko, I., Heim, K., Blackburn, H., Ried, J.S., Kleber, M.E., Mangino, M., Thorand, B., Peters, A., Hammond, C.J., Grallert, H., Böhm, B.O., Kovacs, P., Geistlinger, L., Prokisch, H., Winkelmann, B.R., Spector, T.D., Wichmann, H.E., Stumvoll, M., Soranzo, N., März, W., König, W., Illig, T., Gieger, C. Genome-wide association study identifies two novel Regions at 11p15.5-p13 and 1p31 with major impact on acute-phase serum amyloid A. PLoS Genet. 6, e1001213, 2010

313. Svensson M, Dahle DO, Mjøen G, Weihrauch G, Scharnagl H, Dobnig H, März W, Jardine A, Fellström B, Holdaas H. Osteoprotegerin as a predictor of renal and cardiovascular outcomes in renal transplant recipients: follow-up data from the ALERT study. Nephrol Dial Transplant. 2011 Dec 15. [Epub ahead of print] PubMed PMID: 22172725.

314. Leistner DM, Klotsche J, Pieper L, Stalla GK, Lehnert H, Silber S, März W, Wittchen HU, Zeiher AM; for the

DETECT Study Group. Circulating Troponin as Measured by a Sensitive Assay for Cardiovascular Risk Assessment in Primary Prevention. Clin Chem. 2011 Dec 7. [Epub ahead of print] PubMed PMID: 22156668.

315. Jaffer I, Riederer M, Shah P, Peters P, Quehenberger F, Wood A, Scharnagl H, März W, Kostner KM, Kostner GM. Expression of fat mobilizing genes in human epicardial adipose tissue. Atherosclerosis. 2012 Jan;220(1):1227. Epub 2011 Nov 2. PubMed PMID: 22100250.

316. Tomaschitz A, Pilz S, Ritz E, Grammer T, Amrein K, Merger S, Meinitzer A, Winkelmann BR, Boehm BO, März W. Relationship between plasma aldosterone concentration and soluble cellular adhesion molecules in patients referred to coronary angiography. Exp Clin Endocrinol Diabetes. 2011 Nov; 119(10):649-55. Epub 2011 8. PubMed PMID: 22068558.

317. Friedrich N, Schneider HJ, Haring R, Nauck M, Völzke H, Kroemer HK, Dörr M, Klotsche J, Jung-Sievers C, Pittrow D, Lehnert H, März W, Pieper L, Wittchen HU, Wallaschofski H, Stalla GK. Improved prediction of all-cause mortality by a combination of serum total testosterone and insulin-like growth factor I in adult men. Steroids. 2012 Jan; 77(1-2):52-8. Epub 2011 Oct 20. PubMed PMID: 22037276.

318. Kleber ME, Wolfert RL, De Moissl GD, Grammer TB, Dietz S, Winkelmann BR, Boehm BO, März W. Lipoprotein associated phospholipase A2 concentration predicts total and cardiovascular mortality independently of established risk factors (The Ludwigshafen Risk and Cardiovascular Health Study). Clin Lab. 2011; 57(9-10):659-67. PubMed PMID: 22029180.

319. Pilz S, Kienreich K, Drechsler C, Ritz E, Fahrleitner-Pammer A, Gaksch M, Meinitzer A, März W, Pieber TR, Tomaschitz A. Hyperparathyroidism in Patients with Primary Aldosteronism: Cross-Sectional and Interventional Data from the GECOH Study. J Clin Endocrinol Metab. 2011 Oct 19. [Epub ahead of print] PubMed PMID: 22013107.

320. Grallert H, Dupuis J, Bis JC, Dehghan A, Barbalic M, Baumert J, Lu C, Smith NL, Uitterlinden AG, Roberts R, Khuseyinova N, Schnabel RB, Rice KM, Rivadeneira F, Hoogeveen RC, Fontes JD, Meisinger C, Keaney JF Jr, Lemaitre R, Aulchenko YS, Vasan RS, Ellis S, Hazen SL, van Duijn CM, Nelson JJ, März W, Schunkert H, McPherson RM, Stirnadel-Farrant HA, Psaty BM, Gieger C, Siscovick D, Hofman A, Illig T, Cushman M,

Yamamoto JF, Rotter JI, Larson MG, Stewart AF, Boerwinkle E, Witteman JC, Tracy RP, Koenig W, Benjamin EJ, Ballantyne CM. Eight genetic loci associated with variation in lipoprotein-associated phospholipase A2 mass and activity and coronary heart disease: meta-analysis of genome-wide association studies from five community-based studies. Eur Heart J. 2011 Oct 14. [Epub ahead of print] PubMed PMID: 22003152.

321. IBC 50K CAD Consortium. Large-scale gene-centric analysis identifies novel variants for coronary artery disease. PLoS Genet. 2011 Sep;7(9):e1002260. Epub 2011 Sep 22. PubMed PMID: 21966275; PubMed Central PMCID: PMC3178591.

322. Morgan TM, House JA, Cresci S, Jones P, Allayee H, Hazen SL, Patel Y, Patel RS, Eapen DJ, Waddy SP, Quyyumi AA, Kleber ME, März W, Winkelmann BR, Boehm BO, Krumholz HM, Spertus JA. Investigation of 95 variants identified in a genome-wide study for association with mortality after acute coronary syndrome. BMC Med Genet. 2011 Sep 29;12:127. PubMed PMID: 21957892; PubMed Central PMCID: PMC3190329.

323. Silbernagel G, Kleber ME, Grammer TB, Winkelmann BR, Boehm BO, März W. Additional use of glycated hemoglobin for diagnosis of type 2 diabetes in people undergoing coronary angiography reveals a subgroup at increased cardiovascular risk. Diabetes Care. 2011 Nov;34(11):2471-3. Epub 2011 Sep 12. PubMed PMID: 21911772; PubMed Central PMCID: PMC3198301.

324. International Consortium for Blood Pressure Genome-Wide Association Studies, Ehret GB, Munroe PB, Rice KM, Bochud M, Johnson AD, Chasman DI, Smith AV, Tobin MD, Verwoert GC, Hwang SJ, Pihur V, Vollenweider P, O'Reilly PF, Amin N, Bragg-Gresham JL, Teumer A, Glazer NL, Launer L, Zhao JH, Aulchenko Y, Heath S, Sõber S, Parsa A, Luan J, Arora P, Dehghan A, Zhang F, Lucas G, Hicks AA, Jackson AU, Peden JF, Tanaka T, Wild SH, Rudan I, Igl W, Milaneschi Y, Parker AN, Fava C, Chambers JC, Fox ER, Kumari M, Go MJ, van der Harst P, Kao WH, Sjögren M, Vinay DG, Alexander M, Tabara Y, Shaw-Hawkins S, Whincup PH, Liu Y, Shi G, Kuusisto J, Tayo B, Seielstad M, Sim X, Nguyen KD, Lehtimäki T, Matullo G, Wu Y, Gaunt TR, Onland-Moret NC, Cooper MN, Platou CG, Org E, Hardy R, Dahgam S, Palmen J, Vitart V, Braund PS, Kuznetsova T, Uiterwaal CS, Adeyemo A, Palmas W, Campbell H, Ludwig B, Tomaszewski M, Tzoulaki I, Palmer ND; CARDIoGRAM consortium; CKDGen Consortium; KidneyGen Consortium; EchoGen consortium; CHARGE-HF consortium, Aspelund T, Garcia M, Chang YP, O'Connell JR, Steinle NI, Grobbee DE, Arking DE, Kardia SL, Morrison AC, Hernandez D, Najjar S, McArdle WL, Hadley D, Brown MJ, Connell JM, Hingorani AD, Day IN, Lawlor DA, Beilby JP, Lawrence RW, Clarke R, Hopewell JC, Ongen H, Dreisbach AW, Li Y, Young JH, Bis JC, Kähönen M, Viikari J, Adair LS, Lee NR, Chen MH, Olden M, Pattaro C, Bolton JA, Köttgen A, Bergmann S, Mooser V, Chaturvedi N, Frayling TM, Islam M, Jafar TH, Erdmann J, Kulkarni SR, Bornstein SR, Grässler J, Groop L, Voight BF, Kettunen J, Howard P, Taylor A, Guarrera S, Ricceri F, Emilsson V, Plump A, Barroso I, Khaw KT, Weder AB, Hunt SC, Sun YV, Bergman RN, Collins FS, Bonnycastle LL, Scott LJ, Stringham HM, Peltonen L, Perola M, Vartiainen E, Brand SM, Staessen JA, Wang TJ, Burton PR, Artigas MS, Dong Y, Snieder H, Wang X, Zhu H, Lohman KK, Rudock ME, Heckbert SR, Smith NL, Wiggins KL, Doumatey A, Shriner D, Veldre G, Viigimaa M, Kinra S, Prabhakaran D, Tripathy V, Langefeld CD, Rosengren A, Thelle DS, Corsi AM, Singleton A, Forrester T, Hilton G, McKenzie CA, Salako T, Iwai N, Kita Y, Ogihara T, Ohkubo T, Okamura T, Ueshima H, Umemura S, Eyheramendy S, Meitinger T, Wichmann HE, Cho YS, Kim HL, Lee JY, Scott J, Sehmi JS, Zhang W, Hedblad B, Nilsson P, Smith GD, Wong A, Narisu N, Stan�áková A, Raffel LJ, Yao J, Kathiresan S, O'Donnell CJ, Schwartz SM, Ikram MA, Longstreth WT Jr, Mosley TH, Seshadri S, Shrine NR, Wain LV, Morken MA, Swift AJ, Laitinen J, Prokopenko I, Zitting P, Cooper JA, Humphries SE, Danesh J, Rasheed A, Goel A, Hamsten A, Watkins H, Bakker SJ, van Gilst WH, Janipalli CS, Mani KR, Yajnik CS, Hofman A, Mattace-Raso FU, Oostra BA, Demirkan A, Isaacs A, Rivadeneira F, Lakatta EG, Orru M, Scuteri A, Ala-Korpela M, Kangas AJ, Lyytikäinen LP, Soininen P, Tukiainen T, Würtz P, Ong RT, Dörr M, Kroemer HK, Völker U, Völzke H, Galan P, Hercberg S, Lathrop M, Zelenika D, Deloukas P, Mangino M, Spector TD, Zhai G, Meschia JF, Nalls MA, Sharma P, Terzic J, Kumar MV, Denniff M, Zukowska-Szczechowska E, Wagenknecht LE, Fowkes FG, Charchar FJ, Schwarz PE, Hayward C, Guo X, Rotimi C, Bots ML, Brand E, Samani NJ, Polasek O, Talmud PJ, Nyberg F, Kuh D, Laan M, Hveem K, Palmer LJ, van der Schouw YT, Casas JP, Mohlke KL, Vineis P, Raitakari O, Ganesh SK, Wong TY, Tai ES, Cooper RS, Laakso M, Rao DC, Harris TB, Morris RW, Dominiczak AF, Kivimaki M, Marmot MG, Miki T, Saleheen D, Chandak GR, Coresh J, Navis G, Salomaa V, Han BG, Zhu X, Kooner JS, Melander O, Ridker PM, Bandinelli S, Gyllensten UB, Wright AF, Wilson JF, Ferrucci L, Farrall M, Tuomilehto J, Pramstaller PP, Elosua R, Soranzo N, Sijbrands EJ, Altshuler D, Loos RJ, Shuldiner AR, Gieger C, Meneton P, Uitterlinden AG, Wareham NJ, Gudnason V, Rotter JI, Rettig R, Uda M, Strachan DP, Witteman JC, Hartikainen AL, Beckmann JS, Boerwinkle E, Vasan RS, Boehnke M, Larson MG, Järvelin MR, Psaty BM, Abecasis GR, Chakravarti A, Elliott P, van Duijn CM, Newton-Cheh C, Levy D, Caulfield MJ, Johnson T, Tang H, Knowles J, Hlatky M, Fortmann S, Assimes TL, Quertermous T, Go A, Iribarren C, Absher D, Risch N, Myers R, Sidney S, Ziegler A, Schillert A, Bickel C, Sinning C, Rupprecht HJ, Lackner K, Wild P, Schnabel R, Blankenberg S, Zeller T, Münzel T, Perret C, Cambien F, Tiret

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325. Suhre K, Shin SY, Petersen AK, Mohney RP, Meredith D, Wägele B, Altmaier E; CARDIoGRAM, Deloukas P, Erdmann J, Grundberg E, Hammond CJ, de Angelis MH, Kastenmüller G, Köttgen A, Kronenberg F, Mangino M, Meisinger C, Meitinger T, Mewes HW, Milburn MV, Prehn C, Raffler J, Ried JS, Römisch-Margl W, Samani NJ, Small KS, Wichmann HE, Zhai G, Illig T, Spector TD, Adamski J, Soranzo N, Gieger C. Human metabolic individuality in biomedical and pharmaceutical research. Nature. 2011 Aug 31;477(7362):54-60. doi: 10.1038/nature10354. PubMed PMID:21886157.

326. Strawbridge RJ, Dupuis J, Prokopenko I, Barker A, Ahlqvist E, Rybin D, Petrie JR, Travers ME, Bouatia-Naji N, Dimas AS, Nica A, Wheeler E, Chen H, Voight BF, Taneera J, Kanoni S, Peden JF, Turrini F, Gustafsson S, Zabena C, Almgren P, Barker DJ, Barnes D, Dennison EM, Eriksson JG, Eriksson P, Eury E, Folkersen L, Fox CS, Frayling TM, Goel A, Gu HF, Horikoshi M, Isomaa B, Jackson AU, Jameson KA, Kajantie E, Kerr-Conte J, Kuulasmaa T, Kuusisto J, Loos RJ, Luan J, Makrilakis K, Manning AK, Martínez-Larrad MT, Narisu N, Nastase Mannila M, Ohrvik J, Osmond C, Pascoe L, Payne F, Sayer AA, Sennblad B, Silveira A, Stancáková A, Stirrups K, Swift AJ, Syvänen AC, Tuomi T, van 't Hooft FM, Walker M, Weedon MN, Xie W, Zethelius B; DIAGRAM Consortium; GIANT Consortium; MuTHER Consortium; CARDIoGRAM Consortium; C4D Consortium, Ongen H, Mälarstig A, Hopewell JC, Saleheen D, Chambers J, Parish S, Danesh J, Kooner J, Ostenson CG, Lind L, Cooper CC, Serrano-Ríos M, Ferrannini E, Forsen TJ, Clarke R, Franzosi MG, Seedorf U, Watkins H, Froguel P, Johnson P, Deloukas P, Collins FS, Laakso M, Dermitzakis ET, Boehnke M, McCarthy MI, Wareham NJ, Groop L, Pattou F, Gloyn AL, Dedoussis GV, Lyssenko V, Meigs JB, Barroso I, Watanabe RM, Ingelsson E, Langenberg C, Hamsten A, Florez JC. Genome-wide association identifies nine common variants associated with fasting proinsulin levels and provides new insights into the pathophysiology of type 2 diabetes. Diabetes. 2011 Oct; 60(10):2624-34. Epub 2011 Aug 26. PubMed PMID: 21873549; PubMed Central PMCID: PMC3178302.

327. Hoffmann MM, März W, Genser B, Drechsler C, Wanner C. Lack of association between the Trp719Arg polymorphism in kinesin-like protein-6 and cardiovascular risk and efficacy of atorvastatin among subjects with diabetes on dialysis: The 4D study. Atherosclerosis. 2011 Dec; 219(2):659-62. Epub 2011 Aug 5. PubMed PMID: 21871624.

328. Edelmann F, Tomaschitz A, Wachter R, Gelbrich G, Knoke M, Düngen HD, Pilz S, Binder L, Stahrenberg R, Schmidt A, März W, Pieske B. Serum aldosterone and its relationship to left ventricular structure and geometry in patients with preserved left ventricular ejection fraction. Eur Heart J. 2011 Aug 19. [Epub ahead of print] PubMed PMID: 21856682.

329. Drechsler C, Grootendorst DC, Pilz S, Tomaschitz A, Krane V, Dekker F, März W, Ritz E, Wanner C. Wasting and sudden cardiac death in hemodialysis patients: a post hoc analysis of 4D (Die Deutsche Diabetes Dialyse Studie). Am J Kidney Dis. 2011 Oct; 58(4):599-607. Epub 2011 Aug 5. PubMed PMID: 21820222.

330. Lerchbaum E, Pilz S, Grammer TB, Boehm BO, März W, Obermayer-Pietsch B. High estradiol levels are associated with increased mortality in older men referred to coronary angiography. Exp Clin Endocrinol Diabetes. 2011 Sep; 119(8):490-6. Epub 2011 Aug 2. PubMed PMID: 21811964.

331. Drechsler C, Meinitzer A, Pilz S, Krane V, Tomaschitz A, Ritz E, März W, Wanner C. Homoarginine, heart failure, and sudden cardiac death in haemodialysis patients. Eur J Heart Fail. 2011 Aug; 13(8):852-9. PubMed PMID: 21791541; PubMed Central PMCID: PMC3143829.

332. Lepper PM, Kleber ME, Grammer TB, Hoffmann K, Dietz S, Winkelmann BR, Boehm BO, März W. Lipopolysaccharide-binding protein (LBP) is associated with total and cardiovascular mortality in individuals with or without stable coronary artery disease--results from the Ludwigshafen Risk and Cardiovascular Health Study (LURIC). Atherosclerosis. 2011 Nov; 219(1):291-7. Epub 2011 Jun 13. PubMed PMID: 21722903.

333. Wehr E, Pilz S, Boehm BO, Grammer TB, März W, Obermayer-Pietsch B. Low free testosterone levels are

associated with all-cause and cardiovascular mortality in postmenopausal diabetic women. Diabetes Care. 2011 Aug; 34(8):1771-7. Epub 2011 Jun 29. PubMed PMID: 21715525; PubMed Central PMCID: PMC3142041.

334. Silbernagel G, Hoffmann MM, Grammer TB, Boehm BO, März W. Uric acid is predictive of cardiovascular mortality and sudden cardiac death in subjects referred for coronary angiography. Nutr Metab Cardiovasc Dis. 2011 Jun 22. [Epub ahead of print] PubMed PMID: 21703834.

335. Pilz S, Tomaschitz A, März W, Drechsler C, Ritz E, Zittermann A, Cavalier E, Pieber TR, Lappe JM, Grant WB, Holick MF, Dekker JM. Vitamin D, cardiovascular disease and mortality. Clin Endocrinol (Oxf). 2011 Nov; 75(5):575-84. doi: 10.1111/j.1365-2265.2011.04147.x. PubMed PMID: 21682758.

336. Schneider HJ, Klotsche J, Wittchen HU, Stalla GK, Schopohl J, Kann PH, Kreitschmann-Andermahr I, Wallaschofski H; German KIMS board and of the DETECT study. Effects of growth hormone replacement within the KIMS survey on estimated cardiovascular risk and predictors of risk reduction in patients with growth hormone deficiency. Clin Endocrinol (Oxf). 2011 Dec; 75(6):825-30. doi: 10.1111/j.1365 2265.2011.04137.x. PubMed PMID: 21658091.

337. Sourij H, Meinitzer A, Pilz S, Grammer TB, Winkelmann BR, Boehm BO, März W. Arginine bioavailability ratios are associated with cardiovascular mortality in patients referred to coronary angiography. Atherosclerosis. 2011 Sep; 218(1):220-5. Epub 2011 May 10. PubMed PMID: 21632053.

338. Breitling LP, Rothenbacher D, Grandi NC, März W, Brenner H. Prognostic usefulness of free fatty acids in patients with stable coronary heart disease. Am J Cardiol. 2011 Aug 15;108(4):508-13. Epub 2011 May 31. PubMed PMID: 21624537.

339. Wild PS, Zeller T, Schillert A, Szymczak S, Sinning CR, Deiseroth A, Schnabel RB, Lubos E, Keller T, Eleftheriadis MS, Bickel C, Rupprecht HJ, Wilde S, Rossmann H, Diemert P, Cupples LA, Perret C, Erdmann J, Stark K, Kleber ME, Epstein SE, Voight BF, Kuulasmaa K, Li M, Schäfer AS, Klopp N, Braund PS, Sager HB, Demissie S, Proust C, König IR, Wichmann HE, Reinhard W, Hoffmann MM, Virtamo J, Burnett MS, Siscovick D, Wiklund PG, Qu L, El Mokthari NE, Thompson JR, Peters A, Smith AV, Yon E, Baumert J, Hengstenberg C, März W, Amouyel P, Devaney J, Schwartz SM, Saarela O, Mehta NN, Rubin D, Silander K, Hall AS, Ferrieres J, Harris TB, Melander O, Kee F, Hakonarson H, Schrezenmeir J, Gudnason V, Elosua R, Arveiler D, Evans A, Rader DJ, Illig T, Schreiber S, Bis JC, Altshuler D, Kavousi M, Witteman JC, Uitterlinden AG, Hofman A, Folsom AR, Barbalic M, Boerwinkle E, Kathiresan S, Reilly MP, O'Donnell CJ, Samani NJ, Schunkert H, Cambien F, Lackner KJ, Tiret L, Salomaa V, Munzel T, Ziegler A, Blankenberg S. A genome-wide association study identifies LIPA as a susceptibility gene for coronary artery disease. Circ Cardiovasc Genet. 2011 Aug 1; 4(4):403-12. Epub 2011 May 23. PubMed PMID: 21606135; PubMed Central PMCID: PMC3157552.

340. Tomaschitz A, Pilz S, Ritz E, Morganti A, Grammer T, Amrein K, Boehm BO, März W., Associations of plasma renin with 10-year cardiovascular mortality, sudden cardiac death, and death due to heart failure. Eur Heart J. 2011Nov; 32(21):2642-9. Epub 2011 May 23. PubMed PMID: 21606079.

341. Mikhailidis DP, Elisaf M, Rizzo M, Berneis K, Griffin B, Zambon A, Athyros V, de Graaf J, März W, Parhofer KG, Rini GB, Spinas GA, Tomkin GH, Tselepis AD, Wierzbicki AS, Winkler K, Florentin M, Liberopoulos E. "European panel on low density lipoprotein (LDL) subclasses": a statement on the pathophysiology, atherogenicity and clinical significance of LDL subclasses: executive summary. Curr Vasc Pharmacol. 2011 Sep 1; 9(5):531-2. PubMed PMID: 21595629.

342. Mikhailidis DP, Elisaf M, Rizzo M, Berneis K, Griffin B, Zambon A, Athyros V, de Graaf J, März W, Parhofer KG, Rini GB, Spinas GA, Tomkin GH, Tselepis AD, Wierzbicki AS, Winkler K, Florentin M, Liberopoulos E. "European panel on low density lipoprotein (LDL) subclasses": a statement on the pathophysiology, atherogenicity and clinical significance of LDL subclasses. Curr Vasc Pharmacol. 2011 Sep 1; 9(5):533-71. PubMed PMID: 21595628.

343. Grandi NC, Breitling LP, Hahmann H, Wüsten B, März W, Rothenbacher D, Brenner H. Serum parathyroid hormone and risk of adverse outcomes in patients with stable coronary heart disease. Heart. 2011 Aug; 97(15):1215-21. Epub 2011 May 17. PubMed PMID: 21586795.

344. Ivandic BT, Spanuth E, Kleber M, Grammer TB, März W. High-sensitivity troponin T improves the prognostic value of N-terminal pro-B-type natriuretic peptide in patients with stable coronary artery disease: results from the LURIC Study. Clin Chem Lab Med. 2011 Jun; 49(6):1053-8. Epub 2011 May 17. PubMed PMID: 21574877.

345. Pilz S, Meinitzer A, Tomaschitz A, Drechsler C, Ritz E, Krane V, Wanner C, Boehm BO, März W. Low homoarginine concentration is a novel risk factor for heart disease. Heart. 2011 Aug; 97(15):1222-7. Epub 2011 May 10. PubMed PMID: 21558479.

346. Silbernagel G, Grammer TB, Winkelmann BR, Boehm BO, März W. Glycated hemoglobin predicts all-cause, cardiovascular, and cancer mortality in people without a history of diabetes undergoing coronary angiography. Diabetes Care. 2011 Jun; 34(6):1355-61. Epub 2011 Apr 22. PubMed PMID: 21515847; PubMed Central PMCID: PMC3114349.

347. Dahle DO, Mjøen G, Oqvist B, Scharnagl H, Weihrauch G, Grammer T, März W, Abedini S, Norby GE, Holme I, Fellström B, Jardine A, Holdaas H. Inflammation-associated graft loss in renal transplant recipients. Nephrol Dial Transplant. 2011 Nov; 26(11):3756-61. Epub 2011 Apr 21. PubMed PMID: 21511816.

348. März W, Genser B, Drechsler C, Krane V, Grammer TB, Ritz E, Stojakovic T, Scharnagl H, Winkler K, Holme I, Holdaas H, Wanner C; German Diabetes and Dialysis Study Investigators. Atorvastatin and low-density

lipoprotein cholesterol in type 2 diabetes mellitus patients on hemodialysis. Clin J Am Soc Nephrol. 2011 Jun; 6(6):1316-25. Epub 2011 Apr 14. PubMed PMID: 21493741; PubMed Central PMCID: PMC3109927.

349. Tomaschitz A, Pilz S, März W. Eplerenone in mild heart failure. N Engl J Med. 2011 Apr 7; 364(14):1371; author reply 1372. PubMed PMID: 21470018.

350. Wehr E, Pilz S, Boehm BO, März W, Obermayer-Pietsch B. The lipid accumulation product is associated with increased mortality in normal weight postmenopausal women. Obesity (Silver Spring). 2011 Sep; 19(9):1873-80. doi: 10.1038/oby.2011.42. Epub 2011 Mar 10. PubMed PMID: 21394091.

351. Silbernagel G, Renner W, Grammer TB, Hügl SR, Bertram J, Kleber ME, Hoffmann MM, Winkelmann BR, März W, Boehm BO. Association of TCF7L2 SNPs with age at onset of type 2 diabetes and proinsulin/insulin ratio but not with glucagon-like peptide 1. Diabetes Metab Res Rev. 2011 Jul; 27(5):499-505. doi: 10.1002/dmrr.1194. PubMed PMID: 21384500.

352. Schunkert H, König IR, Kathiresan S, Reilly MP, Assimes TL, Holm H, Preuss M, Stewart AF, Barbalic M, Gieger C, Absher D, Aherrahrou Z, Allayee H, Altshuler D, Anand SS, Andersen K, Anderson JL, Ardissino D, Ball SG, Balmforth AJ, Barnes TA, Becker DM, Becker LC, Berger K, Bis JC, Boekholdt SM, Boerwinkle E, Braund PS, Brown MJ, Burnett MS, Buysschaert I; Cardiogenics, Carlquist JF, Chen L, Cichon S, Codd V, Davies RW, Dedoussis G, Dehghan A, Demissie S, Devaney JM, Diemert P, Do R, Doering A, Eifert S, Mokhtari NE, Ellis SG, Elosua R, Engert JC, Epstein SE, de Faire U, Fischer M, Folsom AR, Freyer J, Gigante B, Girelli D, Gretarsdottir S, Gudnason V, Gulcher JR, Halperin E, Hammond N, Hazen SL, Hofman A, Horne BD, Illig T, Iribarren C, Jones GT, Jukema JW, Kaiser MA, Kaplan LM, Kastelein JJ, Khaw KT, Knowles JW, Kolovou G, Kong A, Laaksonen R, Lambrechts D, Leander K, Lettre G, Li M, Lieb W, Loley C, Lotery AJ, Mannucci PM, Maouche S, Martinelli N, McKeown PP, Meisinger C, Meitinger T, Melander O, Merlini PA, Mooser V, Morgan T, Mühleisen TW, Muhlestein JB, Münzel T, Musunuru K, Nahrstaedt J, Nelson CP, Nöthen MM, Olivieri O, Patel RS, Patterson CC, Peters A, Peyvandi F, Qu L, Quyyumi AA, Rader DJ, Rallidis LS, Rice C, Rosendaal FR, Rubin D, Salomaa V, Sampietro ML, Sandhu MS, Schadt E, Schäfer A, Schillert A, Schreiber S, Schrezenmeir J, Schwartz SM, Siscovick DS, Sivananthan M, Sivapalaratnam S, Smith A, Smith TB, Snoep JD, Soranzo N, Spertus JA, Stark K, Stirrups K, Stoll M, Tang WH, Tennstedt S, Thorgeirsson G, Thorleifsson G, Tomaszewski M, Uitterlinden AG, van Rij AM, Voight BF, Wareham NJ, Wells GA, Wichmann HE, Wild PS, Willenborg C, Witteman JC, Wright BJ, Ye S, Zeller T, Ziegler A, Cambien F, Goodall AH, Cupples LA, Quertermous T, März W, Hengstenberg C, Blankenberg S, Ouwehand WH, Hall AS, Deloukas P, Thompson JR, Stefansson K, Roberts R, Thorsteinsdottir U, O'Donnell CJ, McPherson R, Erdmann J; CARDIoGRAM Consortium, Samani NJ. Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease. Nat Genet. 2011 Mar 6; 43(4):333-8. PubMed PMID: 21378990; PubMed Central PMCID: PMC3119261.

353. Pilz S, Tomaschitz A, Friedl C, Amrein K, Drechsler C, Ritz E, Boehm BO, Grammer TB, März W. Vitamin D status and mortality in chronic kidney disease. Nephrol Dial Transplant. 2011 Nov; 26(11):3603-9. Epub 2011 Mar 4. PubMed PMID: 21378153.

354. Wehr E, Pilz S, Boehm BO, März W, Grammer T, Obermayer-Pietsch B. Low free testosterone is associated with heart failure mortality in older men referred for coronary angiography. Eur J Heart Fail. 2011 May; 13(5):4828. Epub 2011 Feb 20.PubMed PMID: 21339189.

355. C Reactive Protein Coronary Heart Disease Genetics Collaboration (CCGC), Wensley F, Gao P, Burgess S, Kaptoge S, Di Angelantonio E, Shah T, Engert JC, Clarke R, Davey-Smith G, Nordestgaard BG, Saleheen D, Samani NJ, Sandhu M, Anand S, Pepys MB, Smeeth L, Whittaker J, Casas JP, Thompson SG, Hingorani AD, Danesh J. Association between C reactive protein and coronary heart disease: mendelian randomisation analysis based on individual participant data. BMJ. 2011 Feb 15; 342:d548. doi: 10.1136/bmj.d548. PubMed PMID: 21325005; PubMed Central PMCID: PMC3039696.

356. Pilz S, Tomaschitz A, Meinitzer A, Drechsler C, Ritz E, Krane V, Wanner C, Böhm BO, März W. Low serum homoarginine is a novel risk factor for fatal strokes in patients undergoing coronary angiography. Stroke. 2011 Apr; 42(4):1132-4. Epub 2011 Feb 10. PubMed PMID: 21311067.

357. Grammer TB, Hoffmann MM, Renner W, Kleber ME, Winkelmann BR, Böhm BO, März W. Apolipoprotein E genotypes, circulating C-reactive protein and angiographic coronary artery disease: the Ludwigshafen Risk and Cardiovascular Health Study. Atherosclerosis. 2011 Apr; 215(2):487-93. Epub 2011 Jan 21. PubMed PMID: 21310412.

358. Pieper L, Dirmaier J, Klotsche J, Thurau C, Pittrow D, Lehnert H, März W, Koch U, Wittchen HU. [Longitudinal associations between depressive symptoms and type 2 diabetes and their impact on mortality in primary care patients]. Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2011 Jan; 54(1):98-107. German. PubMed PMID: 21246335.

359. Lanktree MB, Guo Y, Murtaza M, Glessner JT, Bailey SD, Onland-Moret NC, Lettre G, Ongen H, Rajagopalan R, Johnson T, Shen H, Nelson CP, Klopp N, Baumert J, Padmanabhan S, Pankratz N, Pankow JS, Shah S, Taylor K, Barnard J, Peters BJ, Maloney CM, Lobmeyer MT, Stanton A, Zafarmand MH, Romaine SP, Mehta A, van Iperen EP, Gong Y, Price TS, Smith EN, Kim CE, Li YR, Asselbergs FW, Atwood LD, Bailey KM, Bhatt D, Bauer F, Behr ER, Bhangale T, Boer JM, Boehm BO, Bradfield JP, Brown M, Braund PS, Burton PR, Carty C, Chandrupatla HR, Chen W, Connell J, Dalgeorgou C, Boer A, Drenos F, Elbers CC, Fang JC, Fox CS, Frackelton EC, Fuchs B, Furlong CE, Gibson Q, Gieger C, Goel A, Grobbee DE, Hastie C, Howard PJ, Huang GH, Johnson WC, Li Q, Kleber ME, Klein BE, Klein R, Kooperberg C, Ky B, Lacroix A, Lanken P, Lathrop M, Li M, Marshall V, Melander O, Mentch FD, Meyer NJ, Monda KL, Montpetit A, Murugesan G, Nakayama K, Nondahl D, Onipinla A, Rafelt S, Newhouse SJ, Otieno FG, Patel SR, Putt ME, Rodriguez S, Safa RN, Sawyer DB, Schreiner PJ, Simpson C, Sivapalaratnam S, Srinivasan SR, Suver C, Swergold G, Sweitzer NK, Thomas KA, Thorand B, Timpson NJ, Tischfield S, Tobin M, Tomaszweski M, Verschuren WM, Wallace C, Winkelmann B, Zhang H, Zheng D, Zhang L, Zmuda JM, Clarke R, Balmforth AJ, Danesh J, Day IN, Schork NJ, de Bakker PI, Delles C, Duggan D, Hingorani AD, Hirschhorn JN, Hofker MH, Humphries SE, Kivimaki M, Lawlor DA, Kottke-Marchant K, Mega JL, Mitchell BD, Morrow DA, Palmen J, Redline S, Shields DC, Shuldiner AR, Sleiman PM, Smith GD, Farrall M, Jamshidi Y, Christiani DC, Casas JP, Hall AS, Doevendans PA, Christie JD, Berenson GS, Murray SS, Illig T, Dorn GW 2nd, Cappola TP, Boerwinkle E, Sever P, Rader DJ, Reilly MP, Caulfield M, Talmud PJ, Topol E, Engert JC, Wang K, Dominiczak A, Hamsten A, Curtis SP, Silverstein RL, Lange LA, Sabatine MS, Trip M, Saleheen D, Peden JF, Cruickshanks KJ, März W, O'Connell JR, Klungel OH, Wijmenga C, Maitland-van der Zee AH, Schadt EE, Johnson JA, Jarvik GP, Papanicolaou GJ; Hugh Watkins on behalf of PROCARDIS, Grant SF, Munroe PB, North KE, Samani NJ, Koenig W, Gaunt TR, Anand SS, van der Schouw YT; Meena Kumari on behalf of the Whitehall II Study and the WHII 50K Group, Soranzo N, Fitzgerald GA, Reiner A, Hegele RA, Hakonarson H, Keating BJ. Meta-analysis of Dense Genecentric Association Studies Reveals Common and Uncommon Variants Associated with Height. Am J Hum Genet. 2011 Jan 7; 88(1):6-18. Epub 2010 Dec 30. PubMed PMID: 21194676; PubMed Central PMCID: PMC3014369.

360. Tomaschitz A, Pilz S, Ritz E, Grammer T, Drechsler C, Boehm BO, März W. Association of plasma aldosterone with cardiovascular mortality in patients with low estimated GFR: the Ludwigshafen Risk and Cardiovascular Health (LURIC) Study. Am J Kidney Dis. 2011 Mar; 57(3):403-14. Epub 2010 Dec 24. PubMed PMID: 21186074.

361. Schneider HJ, Friedrich N, Klotsche J, Schipf S, Nauck M, Völzke H, Sievers C, Pieper L, März W, Wittchen HU, Stalla GK, Wallaschofski H. Prediction of incident diabetes mellitus by baseline IGF1 levels. Eur J Endocrinol. 2011 Feb;164(2):223-9. Epub 2010 Nov 8. PubMed PMID: 21059863.

362. Meinitzer A, Kielstein JT, Pilz S, Drechsler C, Ritz E, Boehm BO, Winkelmann BR, März W. Symmetrical and asymmetrical dimethylarginine as predictors for mortality in patients referred for coronary angiography: the Ludwigshafen Risk and Cardiovascular Health study. Clin Chem. 2011 Jan; 57(1):112-21. Epub 2010 Oct 29. PubMed PMID: 21036946.

363. Pilz S, Tomaschitz A, Drechsler C, Zittermann A, Dekker JM, März W. Vitamin D supplementation: a promising approach for the prevention and treatment of strokes. Curr Drug Targets. 2011 Jan; 12(1):88-96. Review. PubMed PMID: 20795935.