Publikationen 2017 | Institut für Anatomie Leipzig 1. Braune J, Weyer U, Hobusch C, Kern M, Kunath A, Klöting N, Kralisch S, Blüher M, Matz-Soja M, Gebhardt R, Zavros Y, Bechmann I, Gericke M (2017) Hedgehog signaling in myeloid cells impacts on body weight, adipose tissue inflammation and glucose metabolism. Diabetologia 60(5):889-899.

2. Braune J, Weyer U, Hobusch C, Mauer J, Brüning JC, Bechmann I, Gericke M (2017) IL-6 regulates M2 polarization and local proliferation of adipose tissue macrophages in obesity. J Immunology 198(7):2927-2934.

3. Kallendrusch S, Merz F, Mayr S, Bechmann I, Zink M (2017) Long-term Tissue Culture of Adult Brain and Spleen Slices on Nanostructured Scaffolds. Advanced Healthcare Materials. Feb (Epub ahead of print). doi: 10.1002/adhm.201601336

4. Morozov YM, Koch M, Rakic P, Horvath TL (2017) Cannabinoid type 1 receptor-containing axons innervate NPY/AgRP neurons in the mouse arcuate nucleus. Mol Metabol. 6(4): 374-381.

5. Chandra B, Korn A, Maity BK, Rawat A, Adler J, Krueger M, Huster D, Maiti S (2017) Stereo-Isomers Probe Steric-Zippers in Amyloid-β. J Phys Chem B. 121(8):1835-1842.

6. Adler J, Scheidt HA, Lemmnitzer K, Krueger M, Huster D (2017) N-terminal lipid conjugation of amyloid β(1-40) leads to the formation of highly ordered N-terminally extended fibrils. Phys Chem Chem Phys. 19(3):1839-1846.

7. Merkwitz C, Blaschuk O, Winkler J, Schulz A, Prömel S, Ricken AM (2017) Advantages and limitations of Salmon-Gal/tetrazolium salt histochemistry for the detection of LacZ reporter gene activity in murine epithelial tissue. J Histochem Cytochem 65(4):197–206.

8. Lede V, Meusel A, Garten A, Popkova Y, Penke M, Franke C, Ricken A, Schulz A, Kiess W, Huster D, Schöneberg T, Schiller J (2017) Altered hepatic lipid metabolism in mice lacking both the melanocortin type 4 receptor and low density lipoprotein receptor. PLoS One. 12(2):e0172000. doi: 10.1371/journal.pone.0172000.

9. Planitzer U, Hammer N, Bechmann I, Glätzner J, Löffler S, Möbius R, Tillmann BN, Weise D, Winkler D (2017) Positional Relations of the Cervical Vagus Nerve Revisited. Neuromodulation; 20(4):361-8.

10. Kranz A, Bechmann I, Feja C, Kohlhaw KR, Bürkigt T, Lippross L, Dietze N, Löffler S. (2017) Implementation of clinical references for undergraduates in anatomy. Ann Anat. 210, 164-169

11. Merz L, Höbel S, Kallendrusch S, Ewe A, Bechmann I, Franke H, Merz F, Aigner A.(2017) Tumor tissue slice cultures as a platform for analyzing tissue-penetration andbiological activities of nanoparticles. Eur J Pharm Biopharm. Mar;112:45-50. doi: 10.1016/j.ejpb.2016.11.013.

12. Zwirner J, Möbius D, Bechmann I, Arendt T, Hoffmann KT, Jäger C, Lobsien D, Möbius R, Planitzer U, Winkler D, Morawski M, Hammer N (2017) Subthalamic nucleus volumes are highly consistent but decrease age-dependently-a combined magnetic resonance imaging and stereology approach in humans. Hum Brain Mapp. Feb;38(2):909-922. doi: 10.1002/hbm.23427.

13. Cotofana S, Steinke H, Schlattau A, Schlager M, Sykes JM, Roth MZ, Gaggl A, Giunta RE, Gotkin RH, Schenck TL (2017) The Anatomy of the Facial Vein: Implications for Plastic, Reconstructive, and Aesthetic Procedures. Plastic and Reconstructive. 139(6):1346–53. doi: 10.1097/PRS.0000000000003382.

14. Gill N, Nasir A, Douglin J, Pretterklieber B, Steinke H, Pretterklieber M, Cotofana S (2017) Accessory Spleen in the Greater Omentum: Embryology and Revisited Prevalence Rates. Cells, tissues, organs. Apr (Epub ahead of print). doi: 10.1159/000458754.

15. Wolf B, Wiersbicki D, Wolfskämpf T, Höckel M, Steinke H (2017) Die PAS-Reaktion zur Darstellung der ontogenetischen Kompartimentgrenzen in pelvinen Großflächenschnitten: eine neue Methode. Geburtshilfe Frauenheilkd. 77(04):406–29. doi: 10.1055/s-0037-1601496.

16. Rennert C*, Eplinius F*, Hofmann U, Johänning J, Rolfs F, Schmidt-Heck W, Guthke R, Gebhardt R*, Ricken AM*, Matz-Soja M* (2017) Conditional loss of hepatocellular Hedgehog signaling in female mice leads to the persistence of hepatic steroidogenesis, androgenization and infertility. Arch Toxicol 91(11): 3677-3687.*contributed equally as first and senior authors, respectively.

17. Koch M (2017) Cannabinoid receptor signaling in central regulation of feeding behaviour: A Mini-Review. Front Neurosci. 11: 293.

18. Raulien N, Friedrich K, Strobel S, Rubner S, Baumann S, von Bergen M, Körner A, Krueger M, Rossol M, Wagner U (2017) Fatty Acid Oxidation Compensates for Lipopolysaccharide-Induced Warburg Effect in Glucose-Deprived Monocytes. Front Immunol. 8:609.

19. Hanske S, Dyrna F, Bechmann I, Krueger M (2017) Different segments of the cerebral vasculature reveal specific endothelial specifications, while tight junction proteins appear equally distributed. Brain Struct Funct. 222(3):1179-1192.

20. Krueger M, Härtig W, Frydrychowicz C, Mueller W, Reichenbach A, Bechmann I, Michalski D (2016) Stroke-induced blood-brain barrier breakdown along the vascular tree - No preferential affection of arteries in different animal models and in humans. J Cereb Blood Flow Metab. 37(7):2539-2554.

21. Bechor S, Nachmias D, Elia N, Haim Y, Vatarescu M, Leikin-Frenkel A, Gericke M, Tarnovsky T, Las G, Rudich A (2017) Adipose tissue conditioned media support macrophage lipid-droplet biogenesis by interfering with autophagic flux. Biochim Biophys Acta. 1862:1001-1012.

22. Schiefenhövel F, Immig K, Prodinger C, Bechmann I (2017) Indications for cellular migration from the central nervous system to its draining lymph nodes in CD11c-GFP+ bone-marrow chimeras following EAE. Exp Brain Res. 235(7):2151-2166. doi: 10.1007/s00221-017-4956-x

23. Buerger F, Müller S, Ney N, Weiner J, Heiker JT, Kallendrusch S, Kovacs P, Schleinitz D, Thiery J, Stadler SC, Burkhardt R (2017) Depletion of Jmjd1c impairs adipogenesis in murine 3T3_L1 cells. Biochim Biophys Acta. Jul;1863(7):1709-1717. doi: 10.1016/j.bbadis.2017.05.011.

24. Allgeier S und Winter K, Bretthauer G, Guthoff RF, Peschel S, Reichert KM, Stachs O, Köhler B (2017) A Novel Approach to Analyze the Progression of Measured Corneal Sub-Basal Nerve Fiber Length in Continuously Expanding Mosaic Images. Current Eye Research 42(4):549-556. doi: 10.1080/02713683.2016.122197.

25. Siegmund B, Kasten A, Kühn JP, Winter K, Gröttner C, Frerich B (2017) MRI-tracking of transplanted human ASC in a SCID mouse model. Journal of Magnetism and Magnetic Materials 427:151-155. doi: 10.1016/j.jmmm.2016.11.032.

26. Kowtharapu B und Winter K, Marfurt C, Allgeier S, Köhler B, Hovakimyan M, Stahnke T, Stachs O, Guthoff RF (2017) Comparative quantitative assessment of the human corneal sub-basal nerve plexus by in vivo confocal microscopy and histologic staining. Eye 31:481-490. doi: 10.1038/eye.2016.220.

27. Scharner D, Winter K, Brehm W, Kämpfert M, Gittel C (2017) Incisional complications following ventral median coeliotomy in horses: Does suturing of the peritoneum reduce the risk? Tierarztl Prax Ausg G Grosstiere Nutztiere 45(1):24-32. doi: 10.15653/TPG-160536.

28. Ziegler D, Winter K, Strom A, Zhivov A, Allgeier S, Papanas N, Ziegler I, Brüggemann J, Ringel B, Peschel S, Köhler B, Stachs O, Guthoff RD, Roden M (2017) Spatial analysis improves the detection of early corneal nerve fiber loss in patients with recently diagnosed type 2 diabetes. PLoS One 12(3):e0173832. doi: 10.1371/journal.pone.0173832.

29. Sakkas A, Wilde F, Heufelder M, Winter K, Schramm A (2017) Autogenous bone grafts in oral implantology-is it still a "gold standard"? A consecutive review of 279 patients with 456 clinical procedures. Int J Implant Dent 3(1):23. doi: 10.1186/s40729-017-0084-4.

30. Winter K, Scheibe P, Guthoff RF, Allgeier S, Stachs O (2017) Morphometrische Charakterisierung des subbasalen Nervenplexus: Detektion und Analyse von Nervenfasernetzwerken. Der Ophthalmologe 114(7):608-616. doi: 10.1007/s00347-017-0465-3

31. Köhler B, Allgeier S, Barschat A, Guthoff RF, Bohn S, Reichert KM, Stachs O, Winter K, Mikut R (2017) In-vivo-Bildgebung des kornealen Nervenplexus: Vom Einzelbild zur großflächigen Darstellung. Der Ophthalmologe 114(7):601-607. doi: 10.1007/s00347-017-0464-4.

32. Heufelder M, Wilde F, Pietzka S, Mascha F, Winter K, Schramm A, Rana M (2017) Clinical accuracy of waferless maxillary positioning using customized surgical guides and patient specific osteosynthesis in bimaxillary orthognathic surgery. Journal of Cranio-Maxillofacial Surgery Epub ahead of print. doi: 10.1016/j.jcms.2017.06.027.

32. Spindler N, Kaatz F, Feja C, Etz C, Mohr FW, Bechmann I, Josten C, Langer S, Löffler S (2017) Anatomic study of the vascular perfusion of the sternum and its clinical relevance in deep sternal wound infection. GMS Interdiscip Plast Reconstr Surg DGPW 2017; 6

33. Theopold J, Weihs K, Feja C, Marquart B, Josten C, Hepp P (2017) Detection of articular perforations of the proximal humerus fracture using a mobile 3D intensifier- a cadaver study BMC Medical Imaging

34. Liese J and Winter K, Glass A, Bertolini, J, Kämmerer PW, Frerich B, Schiefke I, Remmerbach T (2017) Advances towards fully automated in vivo assessment of oral epithelial dysplasia by nuclear endomicroscopy - A pilot study. Journal of Oral Pathology and Medicine Epub ahead of print. doi: 10.1111/jop.12613.

35. Landmann J, Richter F, Oros-Peusquens A, Shah NJ, Classen J, Neely GG, Richter A, Penninger JM, Bechmann I (2017) Neuroanatomy of pain-deficiency and cross-modal activation in calcium channel subunit (CACN) α2δ3 knockout mice. Brain Struct Funct. Jul 21.

36. Zieger K, Weiner J, Kunath A, Gericke M, Krause K, Kern M, Stumvoll M, Klöting N, Blüher M, Heiker JT (2017) Ablation of kallikrein 7 (KLK7) in adipose tissue ameliorates metabolic consequences of high fat diet-induced obesity by counteracting adipose tissue inflammation in vivo. Cell Mol Life Sci. (in press; doi: 10.1007/s00018-017-2658-y)

37. Wlodarczyk A, Holtman IR, Krueger M, Yogev N, Bruttger J, Khorooshi R, Benmamar-Badel A, de Boer-Bergsma JJ, Martin NA, Karram K, Kramer I, Boddeke EW, Waisman A, Eggen BJ, Owens T (2017) A novel microglial subset plays a key role in myelinogenesis in developing brain. EMBO J. 36(22):3292-3308.

38. Quarta C, Clemmensen C, Zhu Z, Yang B, Joseph SS, Lutter D, Yi CX, Graf E, García-Cáceres C, Legutko B, Fischer K, Brommage R, Zizzari P, Franklin BS, Krueger M, Koch M, Vettorazzi S, Li P, Hofmann SM, Bakhti M, Bastidas-Ponce A, Lickert H, Strom TM, Gailus-Durner V, Bechmann I, Perez-Tilve D, Tuckermann J, Hrab? de Angelis M, Sandoval D, Cota D, Latz E, Seeley RJ, Müller TD, DiMarchi RD, Finan B, Tschöp MH (2017) Molecular Integration of Incretin and Glucocorticoid Action Reverses Immunometabolic Dysfunction and Obesity. Cell Metab. 26(4):620-632.

39. Scheidt HA, Adler J, Zeitschel U, Höfling C, Korn A, Krueger M, Roßner S, Huster D (2017) Pyroglutamate modified Amyloid ß (11- 40) Fibrils are more Toxic than Wildtype Fibrils but Structurally Very Similar. Chemistry. 23(62):15834-15838.

40. Härtig W, Mages B, Aleithe S, Nitzsche B, Altmann S, Barthel H, Krueger, Michalski D (2017) Damaged Neocortical Perineuronal Nets Due to Experimental Focal Cerebral Ischemia in Mice, Rats and Sheep. Front Integr Neurosci. 11:15.

41. Piotrowski C, Lede V, Butthof A, Kaiser N, Hirrlinger PG, Tschöp MH, Schöneberg T, Bechmann I (2017) Open housing drives the expression of immune response genes in the nasal mucosa, but not the olfactory bulb. PLoS One. 2017 Oct 27;12(10):e0187192. doi: 10.1371/journal.pone.0187192.

42. Menzel F, Kaiser N, Haehnel S, Rapp F, Patties I, Schöneberg N, Haimon Z, Immig K, Bechmann I (2017) Impact of X-irradiation on microglia. Oct 10. doi: 10.1002/glia.23239.

43. Hammer N, Hirschfeld U, Strunz H, Werner M, Wolfskämpf T, Löffler S (2017)Can the Diagnostics of Triangular Fibrocartilage Complex Lesions Be Improved by MRI-Based Soft-Tissue Reconstruction? An Imaging-Based Workup and Case Presentation. BioMed Research International 7 Article ID 5870875, doi:10.1155/2017/5870875.

44. Klima S, Hepp P, Löffler S, Cornwell J, Hammer N (2017) A novel phased-concept course for the delivery of anatomy and orthopaedics training in medical education. Anat Sci Educ. 10 372-382

45. Hahne S, Barth T, Löffler S (2017) Verringertes Blutungsrisiko beim Sinuslift durch genaue Kenntnis zwischen der klinischen Situation und dem anatomischen Korrelat. Quintessenz 68, 411-417

46. Puchert M, Pelkner F, Stein G, Angelov DN, Boltze J, Wagner DC, Odoardi F, Flügel A, Streit WJ, Engele J (2017) Astrocytic expression of the CXCL12 receptor, CXCR7/ACKR3 is a hallmark of the diseased, but not developing CNS. Mol Cell Neurosci 85:105-118

47. Steinke H, Wiersbicki D, Speckert M, Merkwitz C, Wolfskämpf T, Wolf B (2018) Periodic acid-Schiff (PAS) reaction and plastination in whole body slices. A novel technique to identify fascial tissue structures. Ann Anat. 216(Supplement C):29–35

48. Mascha F, Winter K, Pietzka S, Heufelder M, Schramm A, Wilde F (2017) Accuracy of computer-assisted mandibular reconstructions using patient-specific implants in combination with CAD/CAM fabricated transfer keys. J Craniomaxillofac Surg 45(11):1884-1897. doi: 10.1016/j.jcms.2017.08.028.

49. Kallendrusch S, Körfer J, Lordick F, Bechmann I (2017) Human tumor slice cultures for cancer research and drug testing. Integr Cancer Sci Therap 4. doi: 10.15761/ICST.1000251

50. Sönnichsen R, Henning L, Blaschke V, Winter K, Körfer J, Hähnel S, Monecke A, Wittekind C, Jansen-Winkeln B, Thieme R, Gockel I, Grosser K, Weimann A, Kubick C, Wiechmann V, Aigner A, Bechmann I, Lordick F, Kallendrusch S (2017) Individual susceptibility analysis using patient-derived tissue slices of colorectal carcinoma. Clinical Colorectal cancer Nov;11 in Press doi: 10.1016/j.clcc.2017.11.002

51. Korn A, McLennan S, Adler J, Krueger M, Surendran D, Maiti S, Huster D (2017) Amyloid β (1-40) Toxicity Depends on the Molecular Contact Between Phenylalanine 19 and Leucine 34. ACS Chem Neurosci. Dec 12.