SYMPOSIUM Biomolecular Imaging Meets Immuno-OncologyKolpinghaus Regensburg, Kongress- & KulturzentrumJuly 15-16, 2019
SPITZE IN DER MEDIZIN. MENSCHLICH IN DER BEGEGNUNG.
ukr.de
General Information
Organizing Committee Marina Kreutz Department of Internal Medicine III University Hospital RegensburgGerhard Liebisch Clinical Chemistry and Laboratory Medicine University Hospital RegensburgPeter Oefner Institute of Functional Genomics University of RegensburgPetr Simek Analytical Chemistry and Metabolomics Biology Centre CAS Budweis
Venue Kolpinghaus Regensburg, Kongress- & Kulturzentrum Adolph-Kolping-Straße 1 93047 Regensburg
Congress Management Britta Haseneder UK3 Congress Management University Hospital Regensburg Franz-Josef-Strauß-Allee 11 93053 Regensburg Germany Phone +49 (0)941 944 4232 Fax +49 (0)941 944 4233 [email protected]
Date July 15-16, 2019
Congress Fee Regular Participation 300 € Students 100 €
Registration under: www.congress-registration.ukr.de
Sponsors
Pfizer Pharma GmbH 1.500 €
Performance for booth fee and advertising purposes.
Speakers and Session ChairsNadine Assmann Department of Biomedicine University and University Hospital Basel Basel, SwitzerlandLuciana Berod Institute of Infection ImmunologyTWIN CORE, Centre for Experimental and Clinical Infection Research Hannover Medical School and Helmholtz Centre for Infection Research Hannover, GermanyTobias Bopp Institute for Immunology Johannes Gutenberg-University Mainz Mainz, GermanyJürgen Burhenne Department of Clinical Pharmacology and Pharmacoepidemiology University Clinic Heidelberg Heidelberg, GermanyRita Casadonte Proteopath GmbH, Trier, GermanyHayo Castrop Institute of Physiology University of Regensburg Regensburg, GermanyGuoliang Cui Deutsches Krebsforschungszentrum Heidelberg Heidelberg, GermanyKatja Dettmer Institute of Functional Genomics University of Regensburg Regensburg, GermanyChristina Ferreira Bindley Bioscience Center Purdue University West Lafayette, IN, USAIsabelle Fournier Laboratoire Protéomique Université de Lille Lille, FranceWolfram Gronwald Institute of Functional Genomics University of Regensburg Regensburg, GermanyKarsten Gülow Department of Internal Medicine I University Hospital Regensburg Regensburg, GermanyJörg Hanrieder Department of Psychiatry and Neurochemistry Sahlgrenka Academy at Gothenburg University Mölndal, SwedenSina-Franziska Heimer Department of Oral and Maxillofacial Surgery University Hospital Regensburg Regensburg, GermanyMathias Holpert NanoString Technologies, Inc. Seattle, WA, USAMarcus Höring Institute of Clinical Chemistry and Laboratory Medicine University Hospital Regensburg Regensburg, GermanyJonathan Jantsch Institute of Microbiology und Hygiene University Hospital Regensburg Regensburg, GermanyUwe Karst Institute of Inorganic and Analytical Chemistry University of Münster Münster, GermanyMary King Department of Chemistry University of Texas at Austin Austin, TX, USAMarina Kreutz Department of Internal Medicine III University Hospital Regensburg Regensburg, Germany
Dieter Kube Department of Haematology and Oncology University Medical Center Göttingen Göttingen, GermanyGerhard Liebisch Institute of Clinical Chemistry and Laboratory Medicine University Hospital Regensburg Regensburg, GermanyJason Locasale Department of Pharmacology and Cancer Biology Duke University School of Medicine Durham, NC, USARémi Longuespée Department of Clinical Pharmacology and Pharmacoepidemiology University Clinic Heidelberg Heidelberg, GermanyMartina Marchetti-Deschmann Institute of Chemical Technologies and Analytics Vienna University of Technologies Vienna, AustriaLiam McDonnell Center for Proteomics and Metabolomics Leiden University Medical Center Leiden, The NetherlandsPeter Oefner Institute of Functional Genomics University of Regensburg Regensburg, GermanyKathrin Renner-Sattler Department of Internal Medicine III University Hospital Regensburg Regensburg, GermanyColinda Scheele Division of Molecular Pathology, Oncode Institute The Netherlands Cancer Institute Amsterdam, The NetherlandsAlmut Schulze Department of Biochemistry and Molecular Biology Theodor-Boveri-Institute University of Würzburg Würzburg, Germany Kristina Schwamborn Institute of Pathology Technical University Munich Munich, GermanyAndrej Shevchenko Max Planck Institute of Molecular Cell Biology and Genetics Dresden, GermanyPeter Siska Department of Internal Medicine III University Hospital Regensburg Regensburg, GermanyAstrid Slany Department of Analytical Chemistry University of Vienna Vienna, AustriaRainer Spang Chair of Bioinformatics University of Regensburg Regensburg, GermanyTim Sparwasser Department of Medical Microbiology and Hygiene Johannes Gutenberg University Mainz Mainz, GermanyBernhard Spengler Institute of Inorganic and Analytical Chemistry Justus Liebig University Giessen Giessen, GermanyIain Styles School of Computer Science University of Birmingham Birmingham, UKZoltan Takats Imperial College London London, UKMichael Witting Department of Environmental Sciences (DES) Helmholtz Zentrum München Neuherberg, Germany
Photo and rights: UKR June 2019
Registration conditionsAfter your successful registration you will receive an invoice for your participation by email. Once registered your registration is binding. All payments must be made prior to the conference. Par-ticipation fees are due upon receipt of invoice without deduction. Please transfer the invoice amount before the event date. In case of a cancellation the cancellation statement must be in writing. The following processing fees apply: 8-3 working days before the event 50% of participa-tion fee. In case of too late cancellation or absence without written cancellation the entire fee will be charged. A substitute participant may be submitted at any time.
Dear colleagues,
the „Bavarian-Bohemian-Metabolism-Network“, a Euro-pean Union funded collaboration between the Institutes of Functional Genomics and Clinical Chemistry at the University of Regensburg and the Laboratory of Analytical Biochemistry and Metabolomics at the Biology Center CAS in Budweis, and the „Else Kröner Research College for Interdisciplinary Translational Immuno-Oncology“ are pleased to announce their joint symposium „Biomolecular Imaging Meets Immuno-Oncology“, which will be held in Regensburg from July 15-16, 2019.
The symposium will bring together national and inter-national leaders in the field of in situ analysis of bio-molecules, drugs and cells to explore the application of imaging techniques in advancing the understanding, diagnosis and therapy of immune and cancer diseases.
We are grateful to the colleagues, who have accepted our invitation to come to Regensburg to present their research. The symposium promises to deliver a compre-hensive review of the current status and potential of bio-molecular imaging in the life sciences and biomedicine.
We hope that you will join us in Regensburg for an exciting exchange of data and ideas, to which you may contribute by poster presentations. We will be happy to assist you in making arrangements for your visit.
Looking foward to seeing you in Regensburg.
Peter Oefner
Welcome Address
Monday, July 15, 201908:25 Opening Remarks
Peter OefnerSession I The Nuts and Bolts of Imaging Biomolecules Session Chairs: Isabelle Fournier, Kristina Schwamborn08:30 Imaging Mass Spectrometry in Bioanalysis
Uwe Karst09:00 Desorption Electrospray Ionization Mass Spectrometry Imaging:
Recent Developments and Perspectives Christina Ferreira
09:30 High Performance MALDI Mass Spectrometry Imaging in the Biomedical Field Bernhard Spengler
10:00 Coffee BreakSession II Cancer and Immune Cell Metabolism Session Chairs: Marina Kreutz, Liam McDonnell10:30 Glucose and Amino Acid Metabolism in Health and Cancer
Jason Locasale11:00 Targeting Cancer Metabolism
Almut Schulze11:30 Metabolic Communication in the Tumor Microenvironment:
New Perspectives on Macrophage Polarization Tobias Bopp
12:00 Metabolic Control of Treg Differentiation Luciana Berod
12:30 Metabolic Checkpoints Controlling Immune Cell Function Tim Sparwasser
13:00 LunchSession III Imaging Mass Spectrometry in Diagnostic Medicine Session Chairs: Christina Ferreira, Uwe Karst14:00 Imaging Mass Spectrometry - Applications in Pathology
Kristina Schwamborn14:30 Imaging Mass Spectrometry Utility in the Area of
Diagnostic Medicine Rita Casadonte
15:00 Molecular Imaging Mass Spectrometry to Probe Neuro-degenerative Disease Pathology Jörg Hanrieder
15:30 Coffee BreakSession IV Cancer and Immune Cell Metabolism Session Chairs: Kathrin Renner-Sattler, Tobias Bopp16:00 T Cell Metabolic Editing in Cancer and Infection
Guoliang Cui16:30 The Citrate-Malate Shuttle is Central to the Metabolic Pheno-
type of Cytokine Activated NK Cells Nadine Assmann
17:00 Cooperation of Jak/STAT and NF-κB Signaling Pathways - Aberrant GOT2 Expression and Glutamine Addiction in Aggressive Lymphoma Dieter Kube
17:30 Glycolytic Insufficiency and Mitochondrial Dysregulation Impair Function of Tumor Infiltrating CD8 T Cells Peter Siska
17:45 Inhibition of Tumor Growth and Metastasis Formation by Energy Depletion Karsten Gülow
18:15 Modulation of the Mitochondrial Pathway of Apoptosis by Hyperosmotic Stress Sina-Franziska Heimer
18:30 O2 in infected tissues and its impact on antimicrobial macro-phage defense mechanisms Jonathan Jantsch
19:00 - 22:00 Networking
Program Program
Tuesday, July, 16, 2019Session V From Imaging Biomolecules to Cells Session Chairs: Isabelle Fournier, Rita Casadonte08:30 Multimodal Imaging
Martina Marchetti-Deschmann09:00 Desorption Electrospray Ionization MS Imaging for Cancer
Diagnosis and Clinical Research Mary King
09:30 Intravital Microscopy Reveals Dynamics of Tissue Homeostasis and Tumor Progression Colinda Scheele
10:00 Deep Insights: New Applications of Intravital Multiphoton Microscopy Hayo Castrop
10:30 Coffee BreakSession VI Computational Challenges in Molecular Imaging Session Chairs: Martina Marchetti-Deschmann, Rainer Spang11:00 Metabolite Mass Spectrometry Imaging: Method Development,
Image Registration and Analysis, Bioinformatics and Statistical Analysis Liam McDonnell
11:30 Dimensionality Reduction and Image Segmentation in Mass Spectrometry Imaging Iain Styles
12:00 Visualization of Molecular Interaction Networks in Tissues by Mass Spectrometric Imaging Zoltan Takats
12:30 Computational Tissue Analysis Rainer Spang
13:00 LunchSession VII From Omics to Biomolecular Imaging Session Chairs: Zoltan Takats, Mary King14:00 Bridging MS Imaging with Spatially - Resolved Omics to Better
Characterize Tumor Microenvironment Isabelle Fournier
14:30 Multi-Omics Analysis to Reveal Immune Evasion and Metabolic Strategies of Tumor Cells Astrid Slany
15:00 Shotgun Lipidomics of Microdissected Tissues: a Complement for Molecular Imaging? Andrej Shevchenko
15:30 Morphology Driven High-Plex Spatial Analysis of Tissue Microenvironments Mathias Holpert
16:00 Coffee BreakSession VIII The Great Finale Session Chairs: Katja Dettmer, Astrid Slany16:30 Mass Spectrometric Imaging and Profiling Methods Meet Liquid
Chromatography for Pharmacological Applications Rémi Longuespée, Jürgen Burhenne
17:00 Quantification and Metabolic Profiling of Lipid Species Gerhard Liebisch
17:30 The Known and the Unknown Metabolism - The need for Metab-olite Identification Michael Witting
18:00 Accurate Quantification of Cholesterol and Cholesteryl Ester Species by FIA-FTMS Marcus Höring
18:15 Prediction of IDH Mutations in Gliomas Based on Full MRS Data Wolfram Gronwald
18:30 Concluding Remarks Peter Oefner