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1 Seite 1 RUPRECHT-KARLS- UNIVERSITY HEIDELBERG Computer Assisted Clinical Medicine Dr. Friedrich Wetterling 11/24/2011 | Page 1 Bildgebende Systeme in der Medizin Magnetresonanztomographie V: Gefahren und Schutzmaßnahmen Dr. Friedrich Wetterling Hochschule Mannheim Computer Assisted Clinical Medicine Faculty of Medicine Mannheim University of Heidelberg Theodor-Kutzer-Ufer 1-3 D-68167 Mannheim, Germany [email protected] www.ma.uni-heidelberg.de/inst/cbtm/ckm/ RUPRECHT-KARLS- UNIVERSITY HEIDELBERG Computer Assisted Clinical Medicine Dr. Friedrich Wetterling | Page 2 MRI System with Superconducting Magnet Siemens Magnetom Symphony B 0 = 1.5 Tesla Quantum-gradient: 30 mT/m slew rate: 125 T/m/s removable patient couch short magnet: 1.6 m relatively open bore 8 receiving channels

Magnetresonanztomographie V: Gefahren und … · • quench pipeline to outdoor ... (deep brain stimulators) ... Standard practice for marking medical devices and other items for

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RUPRECHT-KARLS-UNIVERSITY HEIDELBERG

Computer Assisted Clinical MedicineDr. Friedrich Wetterling

11/24/2011 | Page 1

Bildgebende Systeme in der Medizin

Magnetresonanztomographie V:

Gefahren und Schutzmaßnahmen

Dr. Friedrich Wetterling

Hochschule Mannheim

Computer Assisted Clinical MedicineFaculty of Medicine Mannheim University of HeidelbergTheodor-Kutzer-Ufer 1-3D-68167 Mannheim, GermanyFriedrich.Wetterling@MedMa.Uni-Heidelberg.dewww.ma.uni-heidelberg.de/inst/cbtm/ckm/

RUPRECHT-KARLS-UNIVERSITY HEIDELBERG

Computer Assisted Clinical MedicineDr. Friedrich Wetterling

| Page 2MRI System with Superconducting Magnet

Siemens Magnetom

Symphony

• B0 = 1.5 Tesla

• Quantum-gradient:

30 mT/m

• slew rate: 125 T/m/s

• removable patient couch

• short magnet: 1.6 m

• relatively open bore

• 8 receiving channels

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RUPRECHT-KARLS-UNIVERSITY HEIDELBERG

Computer Assisted Clinical MedicineDr. Friedrich Wetterling

11/24/2011 | Page 3

transmitter

receiver

gradient

shim

ima

ge

p

roce

sso

r350 MHz

control panel

computer

350 MHz

radio- gradients Gxyz static field B0

frequency RF shim coils

MRI Components: Physical Parameters

static field B0 � M0

radiofreq. RF � signal

gradients Gxyz � image

technicalcomponent

physicalparameter

RUPRECHT-KARLS-UNIVERSITY HEIDELBERG

Computer Assisted Clinical MedicineDr. Friedrich Wetterling

| Page 4Operation Mode

normal operation mode

• field exposition where a physiological stress of the patient can be excluded

• routinely control of the patient is adequate

controlled operation mode 1. level

• field exposition where a physiological stress of the patient is possible

• medical patient control is required (i.e. monitoring of physiological parameters)

• MRI system has to notify higher operation mode which has to be confirmed by the operator

controlled operation mode 2. level

• field exposition with a significant risk for the patient

• application possible for clinical testing

• approval by the local ethic commission

• MRI system should not allow an unintended switch

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RUPRECHT-KARLS-UNIVERSITY HEIDELBERG

Computer Assisted Clinical MedicineDr. Friedrich Wetterling

| Page 5Warnings

warnings:

• strong magnetic

field

• radiofrequencyinterdictions:

• cardiac pacemaker

• open fire

• metallic implants

• watch, camera

• magnetic fire extinguisher

• metal: scissor, key

• magnetic disc

RUPRECHT-KARLS-UNIVERSITY HEIDELBERG

Computer Assisted Clinical MedicineDr. Friedrich Wetterling

| Page 6Static Magnetic Field: B0 I

control area: 0.5 mT - line

source: Reiser and Semmler. “Magnetresonanztomographie” 2002

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RUPRECHT-KARLS-UNIVERSITY HEIDELBERG

Computer Assisted Clinical MedicineDr. Friedrich Wetterling

| Page 7Static Magnetic Field: B0 II

control area: 0.5 mT - line

RUPRECHT-KARLS-UNIVERSITY HEIDELBERG

Computer Assisted Clinical MedicineDr. Friedrich Wetterling

| Page 8Static Magnetic Field: B0 = 3 Tesla

control area:

0.5 mT - line

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RUPRECHT-KARLS-UNIVERSITY HEIDELBERG

Computer Assisted Clinical MedicineDr. Friedrich Wetterling

| Page 9

B0

• missile effect

• strong forces to ferromagnetic materials

• forces and torques to implants

• stent

• gunshot wound, rest of projectile

• failure of electromagnetic devices

• cardiac pacemaker

• computer

• controlling system

• physiologic effects

• vertigo when entering the magnet (> 3 Tesla)

B0 - Danger

RUPRECHT-KARLS-UNIVERSITY HEIDELBERG

Computer Assisted Clinical MedicineDr. Friedrich Wetterling

| Page 10B0 – Example I

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RUPRECHT-KARLS-UNIVERSITY HEIDELBERG

Computer Assisted Clinical MedicineDr. Friedrich Wetterling

| Page 11

courtesy: Gross. Siemens Erlangen

B0 – Example II

RUPRECHT-KARLS-UNIVERSITY HEIDELBERG

Computer Assisted Clinical MedicineDr. Friedrich Wetterling

| Page 12B0: Serious Accident of a Fireman

simulated image of accident, courtesy Olbricht. fire department Langenselbold

problem

• no emergency plan of

institution

• insufficient training of fire

department

• neglecting of warnings

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RUPRECHT-KARLS-UNIVERSITY HEIDELBERG

Computer Assisted Clinical MedicineDr. Friedrich Wetterling

| Page 13B0: MR – Compatible Fire Extinguisher

RUPRECHT-KARLS-UNIVERSITY HEIDELBERG

Computer Assisted Clinical MedicineDr. Friedrich Wetterling

| Page 14B0: Emergency Switch-Off Magnet

when ?

• only in case of emergency

• if people have to be saved

• and if saving is not possible due

to magnetic field forces

how ?

• inducing magnet quench

• press “magnet stop” switch

• all persons should be saved and

leave the magnet room quickly

• acute danger of suffocation

• protect magnet room

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RUPRECHT-KARLS-UNIVERSITY HEIDELBERG

Computer Assisted Clinical MedicineDr. Friedrich Wetterling

| Page 15B0: Danger from Cold Gases and Fluids

magnet as pressure tank

• quench

• evaporation of fluid helium

• high pressure

• quench pipeline to outdoor

• cold gases can come into the examination room

• „burning“ at cold surfaces

• displacement of oxygen

• danger of suffocation

RUPRECHT-KARLS-UNIVERSITY HEIDELBERG

Computer Assisted Clinical MedicineDr. Friedrich Wetterling

| Page 16

magnet stop

• interrupts super-conduction,

magnet coil gets normal

conducting

• current in magnet coil comes to

rest

• coil wires get hot and helium

evaporates (quench)

• magnetic field is switched off

emergency stop

• all electric systems of the MR

system are switched off

• magnetic field is still on

• cooling system is off

• magnet stop is still possible since

battery-operated

B0: Magnet Stop and Emergency Stop

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RUPRECHT-KARLS-UNIVERSITY HEIDELBERG

Computer Assisted Clinical MedicineDr. Friedrich Wetterling

| Page 17B1: Gradient Field G(t)

G(t)

• temporal variation of magnetic field

(dB/dt)

• induction of eddy currents in the object / body

• eddy currents run through nerves

• peripheral nerve stimulation

• stimulation of myocardium ?

• interaction with implants

• extreme noise

• ear protection

RUPRECHT-KARLS-UNIVERSITY HEIDELBERG

Computer Assisted Clinical MedicineDr. Friedrich Wetterling

| Page 18B1: Critical Values

PNS - threshold

• threshold of beginning of nerve

stimulation using switching gradients (beginning of stomach prickling)

• is determined in volunteer experiments for each gradient system

• complex function of

• gradient amplitude

• slew rate

• pulse shape

• pulse duration

• number of pulses

• compliance of threshold is done by

software („SAFE model“)

stimulus duration [ms]

dB

/dt[T

/s]

normal 1. level 2. level

80% PNS 100% PNS >100% PNS

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RUPRECHT-KARLS-UNIVERSITY HEIDELBERG

Computer Assisted Clinical MedicineDr. Friedrich Wetterling

| Page 19RF: Radiofrequency

radiofrequency field

• is directly absorbed

• critical value:

specific absorption rate (SAR)

• can be resonant induced in

conductive structures

• creates offset currents in tissue

• massive heating

• flashover

• destroys not connected coils

Wagle and Smith. AJR 2000

RUPRECHT-KARLS-UNIVERSITY HEIDELBERG

Computer Assisted Clinical MedicineDr. Friedrich Wetterling

| Page 20RF: SAR Critical Values

→ patient weight and age are relevant for safety !

body part normal

temperature increase body stem

1. level 2. level

whole body

part body

head

local (head, body)

local (extremities)

scales with the ratio of “exposed patient mass / total patient mass”

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RUPRECHT-KARLS-UNIVERSITY HEIDELBERG

Computer Assisted Clinical MedicineDr. Friedrich Wetterling

| Page 21RF: Flashover

RUPRECHT-KARLS-UNIVERSITY HEIDELBERG

Computer Assisted Clinical MedicineDr. Friedrich Wetterling

| Page 22RF: Burning from Induced Eddy Currents

Kugel et al. Eur Radiol 2003

ECG - system “Tesla plus” EFTES03D, Mammendorfer Institute for Physics and Medicine

„MR compatible“ according to producer !

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RUPRECHT-KARLS-UNIVERSITY HEIDELBERG

Computer Assisted Clinical MedicineDr. Friedrich Wetterling

| Page 23B0 and RF: Implants

contra indication

• cardiac pacemaker

• neuro stimulators

(deep brain stimulators)

• ferromagnetic implants

• gun projectiles

• paramagnetic stents up to 2 weeks after implantation

information

• http://www.mrisafety.com

• Shellock FG. Reference Manual for Magnetic Resonance Safety, Implants, and Devices: 2006 Edition.

RUPRECHT-KARLS-UNIVERSITY HEIDELBERG

Computer Assisted Clinical MedicineDr. Friedrich Wetterling

| Page 24MR Safety Labeling

MR safe

• an item which poses no known hazards in all MR environments

MR conditional

• an item which has been demonstrated to pose no known hazards

in a specified MR environment with specified conditions of use. Field conditions that define the specified MR environment include

• field strength,

• spatial gradient,

• dB/dt (time rate of change of the magnetic field),

• radio frequency (RF) fields, and

• specific absorption rate (SAR).

• additional conditions, including specific configurations of the item,

may be required

MR unsafe

• an item which is known to pose hazards in all MR environments

ASTM International. Standard practice for marking medical devices and other items for safety in the magnetic resonance environment. F 2503-05

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RUPRECHT-KARLS-UNIVERSITY HEIDELBERG

Computer Assisted Clinical MedicineDr. Friedrich Wetterling

| Page 25Light Vizier

patient localizing and referencing

• ask patient for closing eyes before laser switch on

RUPRECHT-KARLS-UNIVERSITY HEIDELBERG

Computer Assisted Clinical MedicineDr. Friedrich Wetterling

| Page 26Danger of Crushing

couch movement

• watch position of arms and fingers

• save connections, ECG-wires, and

alarm ball

• push “couch stop” – patient couch can be moved manually

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RUPRECHT-KARLS-UNIVERSITY HEIDELBERG

Computer Assisted Clinical MedicineDr. Friedrich Wetterling

| Page 27Other Safety Risks

lens effect

• phantoms should not be placed at direct sunlight

RUPRECHT-KARLS-UNIVERSITY HEIDELBERG

Computer Assisted Clinical MedicineDr. Friedrich Wetterling

| Page 28MR Safety Aspects: Summary

static magnetic field

• missile effect

• influencing equipments

• physiological effects

gradients

• peripheral nerve stimulation

• noise

radiofrequency

• heating

• coils connected ?

cold gases / fluids

• suffocation

• “burning”

emergency procedures

• magnet stop

• emergency stop

• couch stop

patient information

• patient information sheet

• alarm ball

control area

• watch and take care about

• unknown people (i.e. service and cleaning people, anesthesia doctors and staff, ...)

• unknown equipment and systems before

bringing into the magnet room

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RUPRECHT-KARLS-UNIVERSITY HEIDELBERG

Computer Assisted Clinical MedicineDr. Friedrich Wetterling

11/24/2011 | Page 29Dr. House…