Hoppe-Seyler's Zeitschrift für Physiologische Chemie

Band 355 — 2. Jahreshälfte

Fortgeführt von A . Kossei, F. Knoop und K. Thomas • Herausgegeben von

A.Butenandt, F . Lynen, G.Weitzel

unter Mitwirkung von K . Bernhard, H . Dannenberg, K . Decker, J. Engel,

H . Hanson, E. Helmreich, H . Herken, B. Hess, N . Hilschmann, H . Hilz, P. Karlson,

FT. L. Kornberg, F. Leuthardt, J. Seelig, G. Siebert, H . Simon, Hj . Staudinger,

W. Stoffel, H . Tuppy, H . G. Zachau

Redaktion A. Dillmann, G. Peters

1974

W A L T E R D E G R U Y T E R • B E R L I N • N E W Y O R K

W DE

Autorenverzeichnis

Die mit * versehenen Seitenzahlen beziehen sich auf Kurzreferate von Tagungen und Konferenzen

Abraham, R. s. J. S. E. Dericks-Tan Ackeren, G. van s. K. W. Bock Ackermann, R. H . , K . - H . Bässler and K. Wagner, The

relation between the blood-level of a substrate and enzyme kinetics studied with glycerol in the rat 576

Acksteiner, B. s. H.-W. Vohland Adler, J., Chemotaxis in bacteria 105* Agarwal, D. P., H . G. Benkmann and H . W. Goedde,

Further studies on the third component of human complement: protein variants and C3 concentration in certain diseases 1169*

Agarwal, D. P. s. L. M . Srivastava Agranoff, B. W., Biochemical concomitants of the

storage of behavioral information 110* Ahlers, B. s. M . Wenzel Ahnefeld, S. s. H . Eckstein Alexander, W. R. s. G. F. Domagk Alim, S., W. Langheinrich and K . Ring, Regulation of

active amino acid transport in growing cells of Streptomyces hydrogenans 1169*

Alt, J. s. E. Heymann Anderer, F. A. s. W.-D. Marggraf Anding-Edel, R. s. R. Renner Armstrong, V. W., and F. Eckstein, 5-Formyluridine

triphosphate, an inhibitor of RNA-polymerase 758 Arndt, R., K . Michelssen and K. Krisch, Isolation and

some properties of an amidase from rat liver micro­somes 1170*

Arnold, B. s. H . U . Weltzien Arnold, H. , U. Seitz und G. W. Lohr, Die Hexokinase

und die Mannosetoxizität der Biene 266 Arnold, H . s. J. Fröhlich Azzi, A. s. G. Loschen

Bachra, B. N . , W. F. van Voorthuizen and D. Brouwer, Preliminary information on the use of amino acid codons in collagen mRNA 1170*

Back, P., K . Spaczynski and W. Gerok, Bile salt glucu-ronides in urine 749

Backs, M . s. M . Boll Baczko, K , D. Braun und N . Hilschmann, Zur Struk­

turregel der Antikörper. Die Primärstruktur einer monoklonalen Immunglobulin-L-Kette vom X-Typ, Subgruppe IV (Bence-Jones Protein Bau) 131

Bahr, W. s. E. Kownatzki Bässler, K. -H. s. R. H . Ackermann Bäuerlein, E., ADP synthesis by oxidation of a copper

(Il)-thiol complex with oxygen 1172* Bald, R. and O. Pongs, Proteins and RNA present in

the peptidyltransferase center as revealed by affinity labeling studies 1171*

Bald, R. s. V. A. Erdmann Balke, E. und W. Scharmann, Untersuchungen an einer

Protease (Elastase) aus Pseudomonas aeruginosa, I I : Charakterisierung des Enzyms 958

Balke, E. s. W. Scharmann Ball, P., H.-O. Hoppen and R. Knuppen, iMetabolism

of oestradiol-17ß and 2-hydroxy-oestradiol-17ß in rat liver slices 1451

Ball, P. and R. Knuppen, Determination of 2-hydroxy-oestrone in the urine during the menstrual cycle 1171*

Ball, P. s. R. Knuppen Balmain, A. and E. Hecker, The effects of tumour

promotors on phospholipid metabolism in mouse epidermis 1171*

Balzer, K. , H . Bojar, H . Boeminghaus and W. Staib, An enzymatic method for isolation of tubules and cells from human kidney cortex 1172*

Balzer, K. s. H . Bojar Bamberg, E., R. Benz, P. Läuger und G. Stark, Carrier-

und Porenmechanismen in Lipidmembranen 104* Bard, S. s. O. H . Wieland Barsy, T. de s. B. Lederer Barth, H . s. W. Lorenz Bartnik, F. and W.-H. Kunau, Characterisation of the

initial reaction in partial degradation of highly unsaturated fatty acids 1172*

Bartnik, F. s. W.-H. Kunau Barton, H . s. F. Drawert Basler, M . s. H . Bojar Bauer, E. s. W. Stoffel Bauer, K. and H . Kleinkauf, Degradation of thyrotro-

pin-releasing hormone (TRH) by serum and hypo­thalamic tissue and its inhibition by analogues of TRH 1173*

Baur, H . and E. Pfaff, Criteria of viability of isolated liver cells 1173*

Bause, E. and G. Legier, Isolation and amino acid sequence of a hexadecapeptide from the active site of ß-glucosidase A 3 from Aspergillus wentii 438

Bayer, E. s. B. Hem mas i Bazin, H . s. V. Starace Beato, M . , Binding of progesterone to uteroglobin

1173* Beato, M . s. H . Bugany Beato, M . s. G. Wengler Beckers, A. s. V. Starace Behbehani, A. s. V. Neuhoff Benaguid, A. s. H . Keller Benkmann, H . G. s. D. P. Agarwal Benecke, B. J., C. Krüger and K. H . Seif art, Rat liver

DNA-dependent RNA nucleotidyltransferases after partial hepatectomy 1174*

Bd. 355 (1974) Autorenverzeichnis 1653

Benz, H . U . s. K. Harzer Benz, R. s. E. Bamberg Berger, K. U . s. D. Schubert Berger, R. and F. A. Hommes, Regulation of pyruvate

oxidation in fetal rat liver mitochondria 1174* Berger, R. s. F. A. Hommes Berkel, Th. J. C. van, Metabolie significance of the two

interconvertible forms of M 2-type pyruvate kinase 1175*

Bermek, E. and U . Ücer, Human ADPR-TF I I and its interactions with the ribosome 1175*

Bermek, E. s. H . Mönkemeyer Bermek, E. s. U . Ücer Bernaert, D., P. Drochmans, W. Penasse and H . Ooms,

Glycogen synthesis in isolated adult rat hepatocytes maintained in suspension or cultured 1175*

Berndt, J. and R. Gaumert, Evidence for an activating-inactivating system of 3-hydroxy-3-methylglutaryI-CoA reductase in mouse liver 905

Bertsch, S. and F. Marks, Effect of fetal calf serum and epidermal growth factor on DNA-synthesis in ex-plants of chick embryo epidermis 1176*

Bertsch, S. and F. Marks, Lack of an effect of epidermal chalone and of tumor-promoting phorbol esters on DNA synthesis in epidermis of newborn mice 1176*

Betz, B. s. C. Markert Betz, J. and L. Träger, Possible control systems in

diendiol-induced synthesis of 20ß-hydroxysteroid dehydrogenase in Streptomyces hydrogenans 1176*

Beurden, W. M . O. van, E. Mulder, W. de Boer and H . J. van der Molen, Steroid hormone receptors in rat testicular tissue 1177*

Bieglmayer, Ch., G. Nahler und H . Ruis, Membranen von Glyoxysomen aus Rizinus-Endosperm; Weitere Untersuchungen über die membrangebundenen Enzyme des Fettsäureabbaus und des Glyoxylat-zyklus 1121

ßierbach, H . s. G. Haag Biggeleben, H . J. s. H . Krippner Billiau, A. s. E. de Clercq Binaglia, L . s. H . Woelk Binczek, E. s. W. Stoffel Birkmann, K. s. H . Faulstich Birkmann, K. s. H . W. Heidt Birkmann, K . s. A. K. Walli Bishop, W. H . s. H . T. Keutmann Bister, K. s. W. Stoffel Blumenstein, M . s. J. Bode Boccu', E. s. A. Fontana Bochert, G. s. R. Krowke Bock, K. W., F. Lorch and G. van Ackeren, Activation

and induction of microsomal UDPGlucuronosyl-transferases in rat liver and Morris hepatomas 1177*

Bode, J., M . Blumenstein and M . A. Raftery, 1 9 F nuclear magnetic resonance studies of structure and function relationships in trifluoro-2-oxopropylated glyceraldehyde-phosphate dehydrogenase 1178*

Böcker, R. s. L . Bohne

Boeken, G., D. Broekaert and P. van Oostveldt, Poly­ploidy and habituation in a long-term callus culture as compared to crown gall tissue in vivo {Helianthus annuus L.) 1178*

Böhlandt, D. s. B. Puschendorf Boeminghaus, H . s. K. Balzer Boer, P., A. Reinking, H . J. M . van Rijn, F. Reuvers

and E. P. Steyn-Parve, Biosynthesis of yeast glyco­proteins: In vitro glycosylation of acid phosphatase 1179*

Boer, P. s. H . J. M . van Rijn Boer, W. de s. W. M . O. van Beurden Bösenberg, H . s. K. Norpoth Bohne, L. , R. Böcker, H . Kersten and W. Kersten,

Effect of thiamin on protein and nucleic acid meta­bolism, IV. Thiamin-dependent incorporation of pyrimidine nucleosides into nucleic acids and pyri-midine diphosphate conjugates in Lactobacillus viridescens 1355

Bohnert, H . J. and J. M . Schmitt, Synthesis of high molecular weight RNA in isolated chloroplasts 1179*

Bohnert, H . J. s. R. G. Herrmann Boie, A. s. H . H . Peters Boie, A. s. B. Stumpf Bojar, H . , K. Balzer, M . Basier, J. L . Wittliff, W. Frö­

lich, W. Staib, N . van der Meulen and C.E.Sekeris, Dexamethasone sensitivity of isolated liver cells as reflected by RNA response and glucocorticoid binding 1180*

Bojar, H. , M. Unnewehr, K. Balzer and W. Staib, Sex differences in the regulation of glucose meta­bolism in isolated thymocytes of rats and humans 1180*

Bojar, H . , J. L. Wittliff, K . Balzer, R. Dreyfürst and W. Staib, Properties of specific estrogen-binding components in immature rat kidney 1181*

Bojar, H . s. K. Balzer Boll, M . , M . Backs und G. Pfleiderer, Quantitative

immunologische Bestimmung von multiplen Formen der Lactat-Dehydrogenase in tierischem und huma­nem Gewebe 811

Bollen, A. s. T. Cabezön Bollert, B. s. M. Wenzel Bontemps, F. s. L . Hue Bonting, S. L. , Biochemistry of visual pigments 99* Boos, W. s. H . M . Kalckar Bornmann, L. and B. Hess, Modification of histidine

residues in yeast pyruvate kinase by diethylpyrocar-bonate 1073

Bouvy, F. s. J. M . Delaisse Bräuning, C. and G. Gercken, Turnover of molecular

species of phosphatidylcholine, phosphatidylethano-lamine and 1,2-diacylglycerol in rabbit brain 1181*

Brand, G., W. Hoffmann and A. Hüttermann, Changes in the specificity of RNA- and protein-degrading enzymes-a possible point of control during diffe­rentiation 1181*

Brand, K. s. K. -H. Quadflieg

1654 Autorenverzeichnis Bd. 355 (1974)

Brandenburg, D. s. A. Wollmer Braun, D. s. K. Baczko Brdiczka, D., G. Dölken, W. Krebs and D. Hofmann,

The inner boundary membrane of mitochondria: Localization and biochemical characterization; possible functions in biogenesis and metabolism 731

Bredehorst, R. s. P. R. Stone Breuer, H . s. M . Höller Breuer, H . s. H.-O. Hoppen Breuer, H . s. G. S. Rao Breuer, H . s. M . L. Rao Breuer, H . s. G. Röhle Broekaert, D. s. G. Boeken Brossmer, R. s. U . Hilgenfeldt Brossmer, R. s. W. E. Merz Brossmer, R. s. P. Wörner Brouwer, D. s. B. N . Bachra Brunfeldt, K. s. J. Halstrom Brunner, G., E. Ferber, J. Golecki, K. Hansen, A.

Huber, H . Knüfermann and K. Resch, Purification of plasma membranes from thymocytes in sugar-free media 1182*

Brunner, H . s. H.-G. Schiefer Brunner, I . s. O. H . Wieland Budzikiewicz, H . s. E. Heinz Bugany, H . and M . Beato, Binding of the glucocorticoid

receptor of liver cytosol to DNA 1182* Burckhardt, W. s. J. Rafael Burr, R., M . Schwenk and E. Pfaff, Studies on the

mechanism of inhibition of mitochondrial respira­tion by bromsulfalein 1182*

Byrd, D. J. s. W. Kochen

Cabezön, T., M . De Wilde, A. Herzog and A. Bollen, Genetical and biochemical studies of neamine-resi-stant mutants in Escherichia coli 1183*

Calberg-Bacq, C. M . , C. Francois, L. Gosselin, P. M. Osterrieth and F. Rentier-Delrue, Preparation and partial chemical analysis of milk fat globule mem­brane and mammary tumour virus obtained from Swiss albino mice 1183*

Calberg-Bacq, C. M. s. P. M . Osterrieth Calker, D. van s. K. Hilse Cantz, M . s. J. F. O'Brien Christophe, A. and G. Verdonk, Effect of prolonged

fasting ion serum lipdis and serum lipoproteins in obese men 1184*

Cichocki, P. s. U . Femfert Clercq, E. de, A. Billiau, J. Hobbs, P. F. Torrence and

B. Witkop, Inhibition of mouse leukemia virus RNA-dependent DNA polymerase by 2'-OH-sub-stituted polynucleotides 1184*

Closset, J. s. G. Maghuin-Rogister Cmelik, S. and E. Fonseca, Composition of mitochon­

drial lipids from rat adrenal glands 19

Cmelik, S. and H . Ley, Fatty acid composition of some cellular and subcellular elements of the elephant adrenal gland 797

Cmelik, S. and H . Ley, Composition of the lipids from the cell sap of the elephant adreanl cortex 1463

Collet-Cassart, D. and R. R. Crichton, Characterisation of two peptides derived from limited proteolysis of apoferritin 1184*

Combarnous, Y. s. G. Maghuin-Rogister Contreras, R. s. W. Min Jou Cooreman, W., A. Lauwers and S. Schärpe, Purification

of stem bromelain by affinity chromatography 1185* Cornells, P., Comparison of some isoaccepting tRNA

species from crown gall and healthy tissues from Nicotiana tabacum 1185*

Cramer, F. s. M . Sprinzl Crichton, R. R. s. D. Collet-Cassart Crichton, R. R. s. J. C. Mareschal Cumps, J. s. M . Roberfroid Czernilofsky, A. P., G. Stoffler und E. Küchler, Mess-

enger-RN A-abhängige Affinitätsmarkierung der 50 S-Untereinheit des Escherichia-coli-Ribosoms 89

Dämmgen, J . s. C. Scholtissek Därr, W. s. W. Stoffel Datta, L . s. L. M . Srivastava Decker, K. s. J. Wilkening De Clercq, E. P. F. Torrence and B. Witkop, Interferon

induction by synthetic polynucleotides: Structure-function relationship 754*

Debuch, H . s. Hj . Fürniss Debuch, H . s. R. Kannan Debuch, H . s. G. Robbers Degkwitz, E., S. Walsch and M . Dubberstein, Influence

of L-ascorbate on the concentrations of microsomal cytochrome P-450 and cytochrome Z>5 in adrenals, kidneys and spleen of guinea pigs 1152

Dekoster, H . s. G. Preaux Delaisse, J. M . , P. Martin, F. Bouvy and E. J. Nyns,

Subcellular distribution of laurate co-hydroxylase in Endomycopsis lipolytica grown on n-hexadecane 1186*

DeLeeuw, G. J. s. J. R. Williamson Denuce, J. M . , R. W. J. Deurenberg-Vos and A. J. M .

de Man, Presence of a natural heteroagglutinin in the serum of the crab Cancer pagurus 1186*

Dericks-Tan, J. S. E, und R. Abraham, Enzymatische hydrierende Esterspaltung von Steroidacetaten in der Lebermikrosomenfraktion 466

Deurenberg-Vos, R. W. J. s. J. M . Denuce Deusser, E. s. H . H . Paradies De Wilde, M . s. T. Cabezön Dieminger, L. s. W. Vogt Dierick, W. s. H . J. Hilderson Dierick, W. s. M . de Wolf Dierickx, L s. P. M . Osterrieth Dijk, W. van s. W. Ferwarda

Bd. 355 (1974) Autorenverzeichnis 1655

Dikow, A. L. s. G. Pfleiderer Diringer, H . and M . A. Koch, Kinetic studies on the

phospholipid metabolism of embryonic mouse cells under conditions of stimulated or restrained growth 93

Diringer, H . and M . A. Koch, A possible function of phosphatidylinositol turnover 1187*

Dirscherl, W. und H . Dohr, Calciumbindung durch Aminosäuren und Peptide, insbesondere durch Poly-a-L-Glutaminsäuren 1135

Dölken, G. and D. Pette, Turnover of several glycolytic enzymes in rabbit heart, soleus muscle and liver 289

Dölken, G. s. D. Brdiczka Doenecke, D. and B. J. McCarthy, Fractionation of

chromatin in sucrose gradients 1187* Doerfler, W. s. E. Fanning Doerfler, W. s. J. Ortin Doerfler, W. s. U . Reif Doering, K. M . s. G. F. Domagk Dörner, M . s. W. E. Merz Dohr, H . s. W. Dirscherl Domagk, G. F., W. R. Alexander and K. M . Doering,

Protein structure and enzymatic activity, X I V : Purification and properties of ribosephosphate iso-merase from skeletal muscle 781

Dormann, P. s. W. Lorenz Drahovsky, D. , A. Wacker and H. Molitor, Enzymatic

methylation of mammalian DNA —a portion of unmethylated genome 1188*

Drahovsky, D. s. H . Krippner Drahovsky, D. s. H . Molitor Drahovsky, D. s. G. Reimer Drawert, F. und H . Barton, Zur enzymatischen Analyse

von Hydroxyprolin, I : Dünnschichtchromatogra­phische Trennung von L - und D-tf//ö-Hydroxyprolin, sowie einiger Hydroxyprolin-Stoffwechselprodukte 902

Dreyfürst, R. s. H. Bojar Drochmans, P. s. D. Bernaert Drochmans, P. s. C. May Drochmans, P. s. J. C. Wanson Dubberstein, M . s. E. Degkwitz Dubischar, N . s. G. Jung Dubois, G. s. M . Roberfroid Duerinck, F. s. W. Min Jou Düppel, W. and V. Ullrich, Membrane effect on drug

mono-oxygenation activity 1188* Düppel, W. s. D. Mansuy

Eckstein, F . s. V. W. Armstrong Eckstein, F. s. J. Lüstorff Eckstein, H . and S. Ahnefeld, Inhibition of E. coli

DNA polymerase by an acid-soluble factor from synchronized growing yeast 1188*

Edelstein, P. s. M . Heller Ee, J. H. van s. J. van't Riet

Eeckhout, Y., K. Otto and G. Vaes, Properties and nature of a lysosomal activator of the proenzyme of bone collagenase 1189*

Egert, D., W. Jonat and H . Maass, Correlation between progesterone binding and in vitro progesterone metabolism in rat uterus 1189*

Egneus, H. , U . Heber and U . Matthiesen, Oxidative phosphorylation in intact chloroplasts 1190*

Ehle, H . s. K. Ring Ehrenspeck, S. s. D. Schubert Ehring, R. s. G. Schumacher Eijk, H . G. van, W. F. Wiltink, J. P. Goossens and

T. H . Tio, Measurement of the diurnal and noctur­nal variations of the serum iron in normal human subjects, of the iron content in human liver speci­mens and in human skin biopsies 1190*

Eijnden, D. H . van den s. W. Ferwerda Eisenstadt, E. s. W. Wille Elbers, R., H . W. Heidt, P. Schmucker, S. Soboll and

H . Wiese, Measurement of the ATP/ADP ratio in mitochondria and in the extramitochondrial com­partment by fractionation of freeze-stopped liver tissue in non-aqueous media 378, 494

Engelhard, M . , M.Hess und N . Hilschmann, Die Primärstruktur einer monoklonalen Immunglobu­li n-L-Kette der Subgruppe I vom X-Typ (Bence-Jones Protein Vor.) 85

Erdmann, V. A., J. R. Hörne, R. Bald, T. Wagner and O. Pongs, Structure and function of ribosomes 757*

Erdmann, V. A., O. Pongs, D. Richter and M . Sprinzl, The involvement of 5S RNA in the binding of tRNA to ribosomes 757*

Erdmann, E. s. R. Patzelt Etzrodt, H . , M . Schleyer and E. F. Pfeiffer, Immuno­

logical relatedness of human and porcine growth hormones 1190*

Etzrodt, H. s. M . Schleyer Eulitz, M . , D. Götze und N . Hilschmann, Die Primär­

struktur einer humanen Immunglobulin-L-Kette vom x-Typ (Bence-Jones-Protein Sew.), I : Tryptische Peptide 819

Eulitz, M . und N . Hilschmann, Die Primärstruktur einer humanen Immunglobulin-L-Kette vom x-Typ (Bence-Jones-Protein Sew.), I I : Chymotryptische Peptide und vollständige Aminosäuresequenz 842

Faillaci, M. G. s. E. Nowotny Falge, C. s. K. Weigand Falke, D. s. D. Schneider Falkenberg, F. s. G. Pfleiderer Fanning, E. and W. Doerfler, Characterization of the

integrated form of adenovirus DNA by reassocia-tion kinetics 1191*

Fasel, P. s. P. Walter Faulstich, H . , Isolation and properties of two cytolytic

glycoproteins from Amanita phalloides mushrooms 1191*

1656 Autorenverzeichnis Bd. 355 (1974)

Faulstich, H. and M . Weckauf-Bloching, Isolation and toxicity of two cytolytic glycoproteins from Amanita phalloides mushrooms 1489

Faulstich, H . , Th. Wieland, A. Walli and K. Birkmann, Antamanide protects hepatocytes from phalloidin destruction 1162

Faulstich, H . , S. Zobeley and M . Weckauf-Bloching, Cytolytic properties of phallolysin 1485

Faust, U . s. F. W. Hulla Felgenhauer, K. , Evaluation of molecular size by gel

electrophoretic techniques 1281 Feller, U . s. E. Latzko Femfert, U . and P. Cichocki, Hydrophobic areas at the

active site of amniopeptidase M 1332 Ferber, E. s. G. Brunner Ferwerda, W., J. F. M . Meijer, D. H . van den Eijnden

and W. van Dijk, Epithelial basement membrane of bovine renal tubuli. Isolation and chemical charac­terization 976

Fiers, W. s. W. Min Jou Fiers, W. s. G. Volckaert Fietzek, P. P. and K. Kühn, The covalent structure of

collagen: Amino acid sequence of the AMerminal region of ot2-CB3 from rat skin collagen and a2-CB3.5 from calf skin collagen 647

Filjak, B. s. J. Hoshino Fischer, G. s. W. Samsel Fischer, K. s. J. Traber Fonseca, E. s. S. Cmelik Fontana, A., E. Boccu' and F. M . Veronese, Purifica­

tion of a phosphodiesterase from the thermophilic fungus Talaromyes duponti 1436

Fragoulis, E. G. and C. E. Sekeris, Translation of mRNA for DOPA decarboxylase, isolated from epidermis of Calliphora vicina larvae, in a heterolo­gous system: dependence of mRNA concentration on the ecdysone titer 1192*

Francois, C. s. C. M . Calberg-Bacq Franke, W. W. s. T. W. Keenan Frans, V. s. M . Kondo Freimüller, B. and F. Heinz, Isoenzymes of trout gly-

ceraldehyde-phosphate dehydrogenase (EC 1.2.1.12) 1192*

Freimüller, B. s. F. Heinz Freimüller, B. s. W. Leicht Freise, J. and I . Trautschold, Energy metabolism and

enzyme release from platelets 1192* Freßmann, L. s. E. Werries Fried, W. s. F. Pittner Friedrichs, D., On the stimulation of gluconeogenesis

by L-lysine 1193* Frischauf, A. M . s. K. H . Scheit Fritz, H . s. W.-D. Schleuning Fritz, H . s. O. Wallner Fröhlich, J., B. Link and H . Arnold, The effect of

mannose on adenine nucleotide content in the isola­ted perfused rat liver 1193*

Frölich, W. s. H . Bojar

Fuchs, E. s. U. Wienand Fuchs, G. and R. Thauer, C 0 2 Fixation via direct C 0 2

reduction: a molybdenum-dependent reaction 1194* Fuchs, G. s. R. Thauer Fuchs, P., A. Kohn and V. Neuhoff, Inhibition of the

tetrahydrofolic acid cycle in HeLa and LDR cells by parainfluenza virus 1 (Sendai) 1021

Fürniss, H . und H . Debuch, Ceramiddigalaktosid aus Schweinepankreas; Reindarstellung und Baustein­analyse 725

Fürniss, H . s. G. Robbers Funcke, Chr., M . Schwenen, M . Steyer, U . Matthiesen

and W. Staib, Steroid metabolism of the isolated perfused rat hindquarter 1194*

Fusenig, N . E. s. W. Samsel

Gallwitz, D. and I . Sures, Initiation in vitro with methionine of ^/-terminal acetylated histones 1194*

Ganser, H . s. J. Huber Gassen, H. G., U . Schwarz and R. Vormbrock, On the

mechanism of codon-anticodon interaction in pro­tein biosynthesis 753*

Gaßmann, J. s. W. Hoppe Gaumert, R. s. J. Berndt Geek, P., L . Lacko and B. Wittke, The effect of steroid

hormones on the glucose transport in erythrocytes 1195*

Geelen, M . J. H . , Control of acetyl-CoA carboxylase activity in isolated rat hepatocytes 1195*

Gehring, TJ., Defective nuclear binding of a steroid hormone receptor 1195*

Geiger, R., W. König, J. Sandow und A. V. Schally, [8-Homoarginin]LH-RH 1526

Geiger, R. s. H . Wissmann Gelbke, H . P. and R. Knuppen, Identification and

quantitative determination of 2-hydroxy-oestradiol-17ß in human pregnancy urine 1196*

Gercken, G. s. C. Bräuning Gerhardt, U . s. H.-G. Schiefer Gerisch, G. and D. Malchow, Chemical signal transfer

during the development of a multicellular organism: The reaction of aggregating Dictyostelium cells to cyclic AMP 108*

Gerisch, G. s. D. Malchow Gerok, W. s. P. Back Gersonde, K. s. H . Sick Geyer, A. s. P. Schmialek Ghraf, R., E. R. Lax, H . Schriefers, A. Wildfeuer, J.

Mühlhäuser and O. Haferkamp, Stereospecificity of the 20-oxo-reduction of C21-steroids by cultures of Candida albicans 1196*

Ghraf, R., U . Vetter und H . Schriefers, Die Organ­spezifität der sexuellen Differenzierung der 17ß-Hydroxysteroid-Dehydrogenase-Aktivitäten der Ratte 543

Ghraf, R. s. E. R. Lax

Bd. 355 (1974) Autorenverzeichnis 1657

Gielen, W. und D. H . Hinzen, Acetylneuraminat-Cytidylyltransferase und Sialyltransferase in iso­lierten Neuronal- und Gliazellen des Rattengehirns 895

Gielen, W. und R. Schaper, Neuraminidase, Acetyl-neuraminat-Cytidylyltransferase und Neuraminyl-transferase in den Leukoz>ten des Menschen 660

Giesing, M . and F. Zilliken, Depletion of medium lipids during organotypical development of cortex cerebri and cerebellum of the rat in vitro 1197*

Gietzen, K. s. H . U . Wolf Gimpel, J. A. s. J. R. Williamson Gleißner, C. s. G. Müllhofer Goedde, H . W. s. D. P. Agarwal Goedde, H . W. s. S. Singh Goedde, H . W. s. L . M . Srivastava Götze, D. s. M . Eulitz Goffeau, A., M . F. Labaille, O. Mohar and A. Tzago-

loff, Common control by a single gene of the syn­theses of cytochrome oxidase and oligomycin-sensitive ATPase 1197*

Golde, L. M . G. van s. W. Renooij Golecki, J. s. G. Brunner Golf, S. W., V. Graef und Hj. Staudinger, Solubilisie-

rung und Anreicherung der NADPH-Cytochrom-Reduktase aus Rattenleber-Mikrosomen 1063

Golf, S. W., V. Graef und Hj. Staudinger, Untersuchun­gen zum Mechanismus der A4-3-Oxosteroid-5a-Reduktion in Rattenleber-Mikrosomen 1499

Goossens, J. P. s. H . G. van Eijk Goracci, G. s. H . Woelk Gosselin, L., Preparation of nonpolar derivatives of

fatty acids and separation according to unsaturation. A simple technique for fatty acid analysis by thin-layer chromatography on unmodified silicagel 1197*

Gosselin, L. s. C. M . Calberg-Bacq Graef, V. s. S. W. Golf Grass, S. s. K. Norpoth Gratzl, M . and D. Schwab, Different intramembranous

location of two microsomal enzymes 1198* Gravier, O. s. M. Roberfroid Greene, E. s. G. W. Tregear Greiling, H . s. P. Muthiah Grimm, W. and F. Marks, Alterations of the level of

cyclic AMP in mouse epidermis after stimulation with tumor-promoting phorbol esters 1198*

Gromova, O. s. V. Mishin Groot, P. H . E., H . R. Schölte and W. C. Hülsmann,

The subcellular localization of acetyl- (EC 6.2.1.1), propionyl- and butyryl-CoA synthetase (EC 6.2.1.2) in rat and guinea-pig organs 1199*

Gross, R. s. H . D. Kaulen Grosskopf, M . s. H . Sies Grünert, A., Problems of fatty acid analysis: critical

review of methods and presentation of a new gas-chromatographic assay with special reference to structural problems 1199*

Grunicke, H . s. F. Hirsch

Grunicke, H . s. H . Keller Grunicke, H. s. B. Puschendorf Grunz, H . s. K. Pollow Gschwendt, M . , Binding of estradiol to the liver chro­

matin of roosters 1199* Guder, W. s. J. Huber Guder, W. G. and A. Rupprecht, a-Adrenergic stimu­

lation of renal gluconeogenesis in isolated kidney tubules 1200*

Guder, W. G. and U . Schmidt, The localization of gluconeogenesis in rat nephron. Determination of phosphoenolpyruvate carboxykinase in microdissec-ted tubules 273

Guntermann, U . , T. Tan and A. Hüttermann, Induction of a-glucosidase during the cell cycle of Myxobacter Al-1 1200*

Guntermann, U . s. A. Hüttermann

Haag, G. and H . Bierbach, Absorption and metabolism of long chain fatty acids in isolated intestinal epithe­lial cells 1201*

Haberland, G. L. s. W.-B. Schill Hachmann, H . J. and A. G. Lezius, A DNA-dependent

ATPase associated with high molecular weight D N A polymerases from mouse myeloma 1201*

Haeffner, E. W., Factors influencing the mode of cho­line uptake by Ehrlich-Lettre-ascites tumor cells in vitro 1201*

Haegeman, G. s. W. Min Jou Häussinger, D. s. H . Sies Haferkamp, O. s. R. Ghraf Hagenmaier, H . E., Enzymatic hydrolysis as a mecha­

nism of hatching in the teleost, Salmo gairdneri Rich 1202*

Hahlbrock, K. s. J. Schröder Hallermayer, G. and W. Neupert, Lipid composition

of mitochondrial outer and inner membranes of Neurospora crassa 279, 494

Halstrom, J., K. Brunfeldt and K. Koväcs, 7V-2-Nitro-phenylsulfenyl amino acid /V-carboxy-anhydrides 82

Hamprecht, B., Cell cultures as model systems for studying the biochemistry of differentiated functions of nerve cells 109*

Hamprecht, B. s. J. Huber Hamprecht, B. s. J. Traber Hanoune, J. s. M.-L. Lacombe Hanoune, J. s. G. Vauquelin Hansen, K. , Glucosidasen als Zuckerrezeptorproteine

bei Fliegen 106* Hansen, K. s. G. Brunner Hartter, P. s. U . Weber Harzer, K. and H . U . Benz, Deficiency of lactosyl sul-

fatide sulfatase in metachromatic leucodystrophy (sulfatidosis) 744

Haueter, G. s. G. S. Rao

1658 Autorenverzeichnis Bd. 355 (1974)

Hausdörfer, J., W, Heller and P. Oldenkott, Alteration of lipid metabolism subsequent to experimental head injury 1202*

Hausdörfer, J. s. W. Heller Havelaar, K. J., Specificity of a bacteriophage T2-indu-

ced DNA methylase 1202* Havemann, K. s. W. Schmidt Heber, U . s. H . Egneus Hecker, E. s. A. Balmain Heimann, G. s. W. Stoffel Heinrich, P. C., R. Liske and K. Reber, The interaction

of native and chemically modified yeast transketo-lase with a specific antibody 217

Heinz, E., J. Rullkötter and H. Budzikiewicz, Acyl digalactosyl diglyceride from leaf homogenates 612

Heinz, F., B. Freimüller and J. Obermeyer, Renal phosphoglycerate kinase (EC 2.7.2.3)

Heinz, F. s. B. Freimüller Heinz, F. s. W. Leicht Heidt, H . W., K. Werdan, A. K. Walli, K. Birkmann

and H . Schimassek, Metabolite uptake into isolated liver cells as measured by silicone layer filtering cen-trifugation 1203*

Heidt, H . W. s. R. Elbers Heller, K. B. and M . Höf er, The effect of nystatin on

the monosaccharide transport system in Rhodotorula gracilis 1203*

Heller, M . , P. Edelstein and M . Mayer, Does the human erythrocyte membrane contain protease activity? 1204*

Heller, W., M . Higi, H . Junger and J. Hausdörfer, Age-dependent interaction of potassium-magnesium-aspartate during general anesthesia. A contribution to lactate-, pyruvate- and ATP-metabolism 1204*

Heller, W. s. J. Hausdörfer Hemmasi, B. and E. Bayer, Coupling of glutamine by

the carbodiimide method in the solid-phase synthesis of two C-terminal peptides of secretin 481

Henkel, W. s. G. Pott Hennen, G. s. G. Maghuin-Rogister Hensgens, H . E. S. J. s. J. R. Williamson Hepp, K. D. s. R. Renner Heremans, J. F. s. V. Starace Herp, F. van, Phosphatase activity in the hepatopan-

creas of the crayfish Astacus leptodactylus 1205* Herrlich, P. s. M . Hirsch-Kauffmann Herrmann, R. G., H. J. Bohnert and K. V. Kowallik,

Arrangement of circular DNA in chloroplasts 1205*

Herrmann, R. G. s. J. M . Schmitt Hers, H . G. s. L. Hue Hers, H . G. s. B. Lederer Herzog, A. s. T. Cabezön Herzog, P. s. K. Sinterhauf Hess, B. s. L. Bornmann Hess, B. s. B. Wurster Hess, M . s. M . Engelhard

Hetzel, W.-D., R. Kiehnscherf and W. Staib, Excretion of isotopically labeled metabolites of testosterone in the bile of male rats 1143

Heymann, E. and J. Alt, On the active center of a bacterial amidase/esterase behaving both as a serine hydrolase and as a thiol enzyme 1205*

Heymann, E. und J. Iglesia, Studium der Mikrohetero-genität und der Untereinheiten-Struktur von Carbo-xylesterasen durch quantitative Bestimmung der terminalen Aminosäuren 1112

Heymann, E., W. Junge, K. Krisch und G. Marcussen-WulfT, Einfache und schnelle Methoden zur Isolie­rung hochgereinigter Carboxylesterasen (EC 3.1.1.1) aus Schweineleber, Rinderleber und Schweinenieren 155

Higi, M . s. W. Heller Hildebrandt, A. and H . W. Sauer, An inhibitor of RNA

polymerase A from Physarum 1206* Hilderson, H . J., M . de Wolf, A. Lagrou and W. Die­

rick, Isopycnic gradient centrifugation (B-XIV zonal rotor) of bovine thyroid microsomes 1206*

Hilderson, H . J. s. M . de Wolf Hilgenfeldt, U . , W. E. Merz and R. Brossmer, Circular

dichroism of human chorionic gonadotropin: A study of the structural characteristics of the hormone and its subunits under different conditions 1051

Hilgenfeldt, U . , T. N . Rabe and W. E. Merz, In vitro test for human chorionic gonadotropin 1207*

Hilgenfeldt, U. s. W. E. Merz Hilschmann, N . s. K. Baczko Hilschmann, N . s. M . Engelhard Hilschmann, N . s. M . Eulitz Hilschmann, N . s. M . Schneider Hilse, K. and D. van Calker, On the frequency of

GpUpG codons within mRNA of the ß-chain of rabbit hemoglobin 1207*

Hilse, K. s. E. Rudloff Hilse, K. s. Th. Sarre Hilz, H . s. P. R. Stone Hinsch, W. and W. Seubert, Tissue-specific characteri­

zation of mitochondrial chain elongation of fatty acids in liver, kidney cortex and heart 1207*

Hinzen, D. H . s. W. Gielen Hirsch, F., H.Wolf and H. Grunicke, Effect of tri-

ethyleneiminobenzoquinone (Trenimon) on thymi­dine transport in Ehrlich ascites tumor cells 1208*

Hirsch-Kauffmann, M . , M . Schweiger, P. Herrlich, H . Ponta, H.-J. Rahmsdorf, S. H . Pai and H.-G. Wittmann, Transcriptional units for ribosomal pro­teins 1208*

Hlavica, P. and M . Kehl, Studies on the mechanism of hepatic microsomal TV-oxide formation, I : Effect of carbon monoxide on the N-oxidation of N,N-dimethylaniline 1508

Hobbs, J. s. E. de Clercq Hochstraßer, K. und K. Schorn, Differenzierung pro­

teolytischer Enzyme durch selektive Hemmung kom­biniert mit elektrophoretischer Darstellung am Bei-

Bd. 355 (1974) Autoren verzeichn is 1659

spiel purulenter Schleimhautsekrete. Ein Beitrag zur negativen enzymatischen Anfärbung 640

Höfer, M. s. K . B. Heller Höfer, M. s. P. C. Misra Höller, M . and H.Breuer, Metabolism of [4- 1 4C]

oestrone in the isolated, hemoglobin-free perfused rat liver: Comparative studies at 28°C and 37°C 1208*

Höller, M . s. M . L. Rao Hoenders, H . J. s. F. S. M . van Kleef Hörmann, H . s. W. Jilg Hörmann, H . s. W. Ströder Hoff, H.-G. s. E. R. Lax Hoffmann, W. s. G. Brand Hoffmann-Ostenhof, O. s. F. Pittner Hoffmann-Ostenhof, O. s. W. Woloszczuk Hofmann, D . s. D. Brdiczka Hohorst, H.-J. s. J. Rafael Holzmann, P. s. D. Müller-Enoch Hommes, F. A. and R. Berger, The control of glycolysis

in isolated fetal rat liver cells 1209* Homines, F. A. s. R. Berger Hommes, F. A. s. H . J. Kloosterboer Hooghwinkel, G. J. M . s. B. Overdijk Hoppe, J., B. Jastorff, N . Panitz, E. Rieke and K. G.

Wagner, Substituted cAMPs: Conformation and interaction with specific enzymes 1209*

Hoppe, W., J. Gaßmann, N . Hunsmann, H . J.Schramm and M . Sturm, Three-dimensional reconstruction of individual negatively stained yeast fatty acid syn­thetase molecules from tilt series in the electron microscope 1483, 1568

Hoppen, H.-O., L. Siekmann und H . Breuer, Stoff­wechsel von Östron in der Mikrosomenfraktion der Rattenleber 1305

Hoppen, H.-O. s. P. Ball Horn, H . s. W. Voelter Hörne, J. R. s. V. A. Erdmann Hoshino, J., U. Kühne, B. Filjak and H. Kröger,

Regulatory changes in the activity of L-serine: pyru­vate aminotransferase and its response to cyclic AMP cortisone in regenerating rat liver 1210*

Hoshino, J., D. Simon, B. Robert and H . Kröger, Dietary and cortisone regulation of cytosol serine and phosphoserine aminotransferases in rat liver 4

Hubbard, R., Cephalopod retinochrome 100* Huber, A. s. G. Brunner Huber, J., W. Guder, O.-A. Müller, S. Latzin, H . Gan­

ser and B. Hamprecht, Influence of hypophysecto-my, thyroid hormone and insulin on the activity of hydroxymethylglutaryl coenzyme A reductase in rat liver 669

Hubert, E. s. G. Huez Hue, L. , F. Bontemps and H . G. Hers, The effect of

glucose concentration on the interconversion of the two forms of glycogen Phosphorylase and of gly­cogen synthase in isolated rat hepatocytes 1210*

Huebers, E. s. H . Huebers

Huebers, H. , E. Huebers and W. Rummel, Dependence of increased iron absorption by iron-deficient rats on an elutable component of jejunal mucosa 1159

Hülsmann, W. C. s. P. H . E. Groot Hülsmann, W. C. s. H . Jansen Hüttermann, A. and U. Guntermann, Metrizamide in

D 2 0 - a novel solute for the isopycnic banding of proteins 1210*

Hüttermann, A. s. G. Brand Hüttermann, A. s. U . Guntermann Huez, G., G. Marbaix, E. Hubert, M . Leclercq, U .

Nudel, H . Soreq, R. Salomon, B. Lebleu, M . Revel and U . Z. Littauer, Role of the polyadenylic seg­ment in the translation of globin messenger RNA 1211*

Hulla, F. W., and U. Faust, Affinity labeling and chro­matography by means of an ATP-analogue 756*

Hunsmann, N . s. W. Hoppe Hutchinson, D. W., The synthesis of polynucleotides

containing halogenated and oxygenated bases 753* Huth, W., R. Jonas and W. Seubert, Catalytic and

regulatory properties of different mitochondrial acetoacetyl-CoA acetyltransferases from ox liver 1211*

Iglesia, J . s. E. Hey mann

Jackl, G. and W. Sebald, Identification of two products of mitochondrial protein synthesis associated with oliogmycin-sensitive ATPase from Neurospora crassa 1211*

Jacobs, J. W. s. H . T. Keutmann Jaenicke, L. s. U . Menge Jancik, J. and R.Schauer, Sialic acid-a determinant

of the life time of rabbit erythrocytes 395 Jansen, H . and W. C. Hülsmann, Liver and extrahepatic

contributions to overall postheparin serum lipase activity 1212*

Janson, E. s. J. Nittinger Janssens de Varebeke, Ph., Synergic effect of Mg 2® and

spermine on the aminoacylation of tRNA of Pha-seohts vulgaris 1212*

Jastorff, B. s. J. Hoppe Jatzkewitz, H . s. W. Mraz Jeckel, D. , Binding constants of nicotinamide nucleo­

tides to native and modified (tyrosine residue) lactate dehydrogenase 1212*

Jering, H . , G. Schorp and H . Tschesche, Enzymatic cleavage of the N£-acetyl protecting group from lysine in proteins (Kunitz trypsin-kallikrein inhibi­tor) in vitro and in vivo 1129

Jilg, W. and H . Hörmann, Fibrinogen of relatively high solubility, I I I . Residual clottable material in plasma deprived of the majority of fibrinogen 1316

Jonas, R. s. W. Huth Jonat, W. s. D. Egert

1660 Autorenverzeichnis Bd. 355 6 (1974

Jong, J. W. de, On the action of dipyridamole (Persan-tin) on partially purified myocardial adenosine kinase 1213*

Joniau, M . , E. A. M . Stevens and L. Verbist, Anti-rifampicin antibodies produced in the rabbit 1213*

Jost, U. , l-Alkyl-2,3-acyl-^/i-glycerol, the major lipid in the Harderian gland of rabbits 422

Jung, B. s. H. H . Peters Jung, G., D. Leibfritz, M . Ottnad, N . Dubischar and

H. Probst, Dynamic conformations and aggregation of the membrane-active alamethicin 1213*

Junge, W. and K. Krisch, Purification and molecular properties of human liver carboxylesterase 1214*

Junge, W. s. E. Heymann Junge, W. s. K. Krisch Junger, H . s. W. Heller Just, W. W., J. O. Leon-V. and G. Werner, Effect of

polyanions on lysosomes and lysosomal enzymes of rat liver in vitro 1565

Kaißling, K . - E . , Geruchsrezeptoren bei Insekten 108* Kalckar, H . M . and W. Boos, Molecular properties of

the periplasmic galactose-binding protein, the pos­sible chemoreceptor for galactose Chemotaxis in Escherichia coli 106*

Kaluza, G., Inhibited multiplication of Semliki Forest virus caused by impaired glycosylation 1214*

Kanig, K. s. Z. S. Tencheva Kanig, K. s. H . Woelk Kannan, R., H.-B. Tjiong, H . Debuch and H.-R. Wie­

demann, Unusual glycolipids in brain cortex of a visceral lipidosis (Niemann-Pick disease?) 551

Kaplan, J. H. and H . Passow, Asymmetric effects of phlorizin on valinomycin-mediated ion movements across the human erythrocyte membrane 1215*

Kather, H. and B. Simon, Studies on the role of super­ficial fat cell SH-groups in basal and insulin-stimu­lated glucose uptake 1215*

Kaulen, H . D. and R. Gross, Purification and proper­ties of a soluble cyclic AMP-dependent protein kinase of human platelets 471

Keenan, T. W., W. W. Franke and H . Wiegandt, Ganglioside accumulation by transformed murine fibroblast (3T3) cells and canine erythrocytes 1543

Kehl, M . s. P. Hlavica Keller, H . , A. Benaguid and H . Grunicke, Biosynthesis

of nicotinamide adenine dinucleotide in mitochon­dria 1215*

Kemmler, W. and R. Renner, Increased receptor affinity as basis for the enhanced biological activity of turkey insulin 1216*

Kemmler, W. s. G. Löffler Kemmler, W. s. R. Renner Kersten, H . s. L . Bohne Kersten, W. s. L . Bohne Keutmann, H . T., J. W. Jacobs, W. H . Bishop and

R. J. Ryan ; Human luteinizing hormone: Amino-

terminal sequence analysis of the ß submit t usinj [35S]-phenylisothiocyanate 935

Keutmann, H. T. s. G. W. Tregear Khandker, R. s. H . Rübsamen Kiehnscherf, R. s. W.-D. Hetzel Kittler, M . s. P. R. Stone Kleef, F. S. M . van and H . J. Hoenders, Aghgig pro

cesses on molecular level in the eye lens p proteii a-crystallin 1216*

Kleine, R. und P. Spangenberg, Isolierung und CrCharak terisierung der beiden Trypsin-Isoenzyme des es ame rikanischen Flußkrebses Cambarus affinis Sayay 114

Kleinkauf, H . s. K. Bauer Kleinow, W., Influence of cations on the dissocociatio

of mitochondrial and cytoplasmic ribosomes es fror Locusta migratoria 1027, 1168

Kleinow, W. s. B. Lorenz Klenk, H.-D. s. R. T. Schwarz Klingenberg, M . , Adeninnucleotid-Analoga undid Ad<

ninnucleotid-Transport in Mitochondrien 75959* Kloosterboer, H . J. and F. A. Hommes, Contmtrol <

creatine kinase development in rat skeletal nl muse 1216*

Klotz, G. s. H . H . Paradies Kluge, F., Replicative intermediates in bacterioriophaj

Ml3 single stranded DNA synthesis 410 Knobloch, K., Electron transport control by er energ

rich phosphate in Rhodopseudomonaspalustris is 121' Knook, D. L. , Distribution of lysosomal enzyrneme ac

vities between parenchymal and nonparenclnchym cells from rat liver 1217*

Knüfermann, H . s. G. Brunner Knuppen, R. and P. Ball, Metabolism of oestradiüdiol-l'

in rat liver slices 1218* Knuppen, R. s. P. Ball Knuppen, R. s. H . P. Gelbke Koch, F. s. G. Koch Koch, G., H. Kubinski and F. Koch, Inhibition on of pi

tein and RNA synthesis in HeLa cells by piroprotea; released membrane glycopeptides 1218*

Koch, M . A. s. H . Diringer Kochen, W., D. J. Byrd and L. Schiirrle, New atv aspe<

of tryptophan metabolism in untreated -pi phen ketonuria and the urinary indole excretion im in re tion to phenylalanine content of semi-syntheitiqetic di

1218* König, W. s. R. Geiger Königk, E. s. R. D. Walter Kohen, C. s. E. Kohen Kohen, E., D. Schachtschabel, C. Kohen and JB.l B. Tl

rell, Microfluorimetric study of metabolic altesnlteratk in Ehrlich ascites tumor cells following serial rial cu vation in hypertonic media 451

Kohn, A. s. P. Fuchs Kolb, H . J., Identification of the catalytically/ Uy act

form of pyruvate dehydrogenase from pi§g pig he muscle 401

Kolb, H . J. s. R. Renner

Bd. 355 (1974) Autoren Verzeichnis 1661

Kondo, M . , L. Moens, H . Siegers and V. Frans, The poly(A)-containing ribonucleoprotein complexes in the dormant embryos of Artemia salina 1218*

Konings, R. N . H . , Regulation of gene activity in bacteriophage M13 DNA 1219*

Koransky, W. s. H.-W. Vohland Koshland, D. E. Jr., The sensing of chemical gradients

by bacteria 105* Koväcs, K. s. J. Halstrom Kovar, R. s. W. Samsel Kowallik, K. V. s. R. G. Herrmann Kownatzki, E. and W. Bahr, The molecular weight of

J chains of human IgM 600 Krämer, R. s. G. Müllhofer Krassnigg, F., Synthesis of protein-reactive puromycin

analogues 760* Kraus, H., S. Schlenker and D. Schwedesky, Develop­

mental changes of cerebral ketone body utilization in human infants 164

Krause, H . P. und Fr. Schneider, Energiestoffwechsel und Zell Vermehrung von in vitro züchtbaren Ehr-lich-Ascites-Tumorzellen unter Eingriffen in den Sauerstoff-Stoffwechsel 1335

Krebs, W. s. D. Brdiczka Kreutz, W., Die Biomembran-Struktur als Basis der

Energie- und Signalwandlung 102* Krieg, L. and F. Marks, Effect of hyperplasiogenic

agents on mechanisms controlling DNA-synthesis and mitosis (chalones) in adult mouse epidermis 1219*

Krippner, H. , H . J. Biggeleben, D. Drahovsky and A. Wacker, Enzymatic methylation of DNA in stimulated T- and B-lymphocytes 1220*

Krisch, K. and W. Junge, Some catalytic properties of human liver carboxylesterases 1220*

Krisch, K. s. R. Arndt Krisch, K. s. E. Heymann Krisch, K. s. W. Junge Krisch, K. s. P. Moog Kröger, A., The electron transport-coupled phosphory­

lation of the anaerobe Vibrio succinogenes 1220* Kröger, H . s. J. Hoshino Krowke, R., G. Bochert and D. Neubert, Biochemical

and pharmacological action of some nucleotide ana­logues on mammalian embryonic development 755*

Krüger, C. s. B. J. Benecke Krüpe, M. s. H.-G. Schiefer Kruse, P. s. K. Norpoth Kubinski, H. s. G. Koch Küchler, E. s. A. P. Czernilofsky Kuckuk, D. E. s. H . H. Paradies Kühn, K. s. P. P. Fietzek Kühne, U . s. J. Hoshino Kunau, W.-H. and F. Bartnik, Partial purification and

possible physiological function of a 4-enoyl-CoA reductase 1221*

Kunau, W.-H. s. F. Bartnik Kurz, G. s. K.-L. Schimz

Kutzbach, C. and E. Rauenbusch, Preparation and general properties of crystalline penicillin acylase from Escherichia coli ATCC 11105, 45

Labaille, M. F . s. A. Goffeau Lachmann, H . s. G. Lachmann Lachmann, G., H . Lachmann and H . Mauser, New

methods for kinetic analysis of consecutive reaction steps demonstrated by model reactions for enzyme catalysis 1221*

Lacko, L. s. P. Geek Lacombe, M.-L. and J. Hanoune, Epinephrine binding

by rat liver plasma membranes. Effect of guanyl nucleotides and EDTA 1221*

Lacombe, M - L . s. G. Vauquelin Läuger, P. s. E. Bamberg Lafonteyne, J. de and B. Srivastava, Maturation of

phage X DNA: dependence on replication and re­combination 1222*

Lagrou, A. s. H . J. Hilderson Lagrou, A. s. M. de Wolf Lamartiniere, C. A. and G. Weiss, The role of the

glycerolphosphate shuttle in heterogenous liver mitochondria 1549

Lamprecht, W. s. W. Leicht Lamprecht, W. s. J. Lüstorff Langheinrich, W. s. S. Alim Lanka, E. and O. Pongs, Affinity-labeling of ribosomes

with AUG and mRNA analogs 1222* Latzin, S. s. J. Huber Latzin, S. s. J. Traber Latzko, E., G. Zimmermann and U. Feller, Evidence

for a hexosediphosphatase from the cytoplasm of spinach leaves 321

Laube, H. s. V. Maier Lauwers, A. s. W. Cooreman Lax, E. R., H.-G. Hoff, R. Ghraf, E.Schröder and

H. Schriefers, The role of the hypophysis in the regulation of sex differences in the activities of en­zymes involved in hepatic steroid hormone metabo­lism 1223*

Lax, E. R., H.-G. Hoff, R. Ghraf, E. Schröder and H . Schriefers, The role of the hypophysis in the regulation of sex differences in the activities of en­zymes involved in hepatic steroid hormone meta­bolism 1325

Lax, E. R. s. R. Ghraf Lebleu, B. s. G. Huez Leclercq, M . s. G. Huez Lederer, B., T. de Barsy, J. G. Leroy and H . G. Hers,

Glycogen Phosphorylase and its converter enzymes in cultured human fibroblasts 1223*

Legier, G. und F. Witassek, Untersuchungen zum Wir­kungsmechanismus glykosidspaltender Enzyme, V I I I : Anzahl der aktiven Zentren der ß-Glucosi-dasen A und B aus dem Süßmandel-Emulsin durch Fluoreszenzmessungen 617

1662 Autorenverzeichnis Bd. 355 (1974

Legier, G. s. E. Bause Leibfritz, D. s. G. Jung Leicht, W., F. Heinz, B. Freimüller and W. Lamprecht,

Bovine liver aldehyde dehydrogenase 1223* Leimcke, H . s. B. Stumpf Leising, H . s. D. O. Schachtschabel Leon-V, J. O. s. W. W. Just Leroy, J. G. s. B. Lederer Lessmann, D. s. K.-L. Schimz Ley, H . s. S. Cmelik Lezius, A. G., Effects of thiodeoxynucleotides on syn­

thesis, structure and function of double-stranded polydeoxynucleotides 754*

Lezius, A. G., Basic proteins stimulating RNA poly­merase A from mouse myeloma 1224*

Lezius, A. G. s. H . J. Hachmann Lindner, E. s. H . Wissmann Link, B. s. J. Fröhlich Liske, R. s. P. C. Heinrich Littauer, U . Z. s. G. Huez Löffler, G. and W. Kemmler, Calcium-ATPase in rat

islets of Langerhans 1224* Löffler, G. s. L. Weiss Löffler, G. s. O. H . Wieland Löffler, H . G. and Fr. Schneider, On the reaction of

papain and succinylpapain with diazo-l-H-tetrazole 1224*

Löffler, M . and Fr. Schneider, On the number, reacti­vity and function of SH-groups at the surface of Ehrlich ascites tumor cells 1225*

Lohr, G. W. s. H . Arnold Lohmann, J., H . Schriewer and H . M . Rauen, Studies

on hepatic phospholipid metabolism in liver micro­somes of rats intoxicated with thioacetamide 1225*

Lommer, D. s. K. Sinterhauf Loontiens, F. G. and J. P. van Wauwe, Binding of

synthetic glycosides to concanavalin A 1225* Lorch, F. s. K. W. Bock Lorenz, B., W. Kleinow and H . Weiss, Mitochondrial

translation of cytochrome b in Neurospora crassa and Locusta migratoria 300

Lorenz, W., H . Barth, M . Thermann, A. Schmal, P. Dormann and I . Niemeyer, Fluorometric histamine determination in canine plasma under normal con­ditions, following application of exogenous hista­mine, and during histamine release by Haemaccel 1097

Loschen, G. and A. Azzi, Formation of oxygen radi­cals and hydrogen peroxide in mitochondrial mem­branes 1226*

Loy, E. s. G. Müllhofer Lubbers, D. W. s. R. Wodick Lüstorff, J., E. Schlimme, F. Eckstein and W. Lamp-

recht, Effects of thiophosphate analogues of ATP and A DP on the ATP-synthetase reaction of oxida­tive phosphorylation 1400

Lyakhovich, V. s. V. Mishin Lynen, R. s. W. Vogt

Maass, H . s. D. Egert Maghuin-Rogister, G., Y. Combarnous, J. L. Vanda-

lem, J. Closset and G. Hennen, Binding of luteiniz­ing hormone to functional collagenase-isolated testi­cular interstitial cells 1226*

Maier, G. and D. Werner, A factor reducing protein and DNA synthesis in Ehrlich ascites tumour cells. Purification and characterisation 1227*

Maier, V., H . Laube and E. F. Pfeiffer, Neuraminidase activity of the pancreas and insulin secretion 1227*

Malchow, D. and G. Gerisch, Recognition of extra­cellular cyclic AMP by aggregating cells of the slime mold, Dictyostelium discoideum 756*

Malchow, D. s. G. Gerisch Man, A. J. M . de s. J. M . Denuce Mannherz, H . G., The interaction of the myosin-sub-

strate complex with actin 758* Mansuy, D., W. Düppel, H . H . R u f and V.Ullrich,

Phosphines as ligands to microsomal cytochrome P-450 1341

Manteuffel, M . s. V. Starace Marbaix, G. s. G. Huez Marcussen-Wulff, G. s. E. Heymann Mareschal, J. C., E. Schonne and R. R. Crichton, Puri­

fication and properties of fructose diphosphate aldolase from calamary muscle 1228*

Marggraf, W.-D. and F. A. Anderer, Alternative path­ways in the biosynthesis of sphingomyelin and the role of phosphatidylcholine, CDPcholine and phosphorylcholine as precursors 803

Marggraf, W.-D. and F. A. Anderer, Alternative path­ways in the biosynthesis of phosphatidylserine in mouse cells 1299

Markert, C., B. Betz and L. Träger, The testosterone 17ß-dehydrogenase of Streptomyces hydrogenans. A comparison with 20ß-hydroxysteroid dehydro­genase from the same microorganism 1228*

Marks, F., Attempts to purify and characterize a factor inhibiting epidermal DNA-synthesis ("Gi-chalone") 1228*

Marks, F. s. S. Bertsch Marks, F. s. W. Grimm Marks, F. s. L. Krieg Martin, P. s. J. M . Delaisse Mattes, R., Investigation of the nucleoside metabolism

in Rhizobium lupini: Obligatory thymidine Phos­phorylase deficiency 1229*

Matthiesen, U . s. H . Egneus Matthiesen, U . s. Chr. Funcke Mauser, H . s. G. Lachmann May, C , P. Drochmans, J. C. Wanson and W. Penasse,

Protein synthesis and ultrastructural changes of isolated hepatocytes incubated in different media 1229*

Mayer, D., Influences of hydrocortisone, thyroxine and insulin on bile acid biosynthesis in rats 1230*

Mayer, M . s. M . Heller McCarthy, B. J. s. D. Doenecke

Bd. 355 (1974) Autorenverzeichnis 1663

McKenna, W. s. R. G. Thurman Meige, W. N . s. P. K. Müller Meijer, A. J. s. J. R. Williamson Meijer, J. F. M. s. W. Ferwerda Mende, G. s. M. Schönharting Menge, U . und L . Jaenicke, Untersuchungen an der

L Asparaginase, Inaktivierung und Modifizierung des Enzyms durch N-Bromsuccinimid und Substrat-spezifität der Reaktion 603

Mercier, M . s. M. Roberfroid Merregaert, J. s. W. Min Jou Merz, W. E. and U . Hilgenfeldt, Responsibility of the

ÖL subunit of human chorionic gonadotropin for the hormone action 1230*

Merz, W. E., U. Hilgenfeldt, R. Brossmer and G. Reh-berger, Amino acid and carbohydrate composition of human chorionic gonadotropin fractions ob­tained by isoelectric focusing 1046

Merz, W. E., U. Hilgenfeldt, M . Dörner and R. Bross­mer, Biological, immunological and physical in­vestigations on human chorionic gonadotropin 1035

Merz, W. E. s. U. Hilgenfeldt Mesecke, S. s. R. Rüchel Mesecke, S. s. D. I . Wolfrum Metz, G., K. -H. Röhm and Fr. Schneider, An amino-

. peptidase from yeast: substrate specificity and some molecular properties 1230*

Meulen, N . van der s. H . Bojar Michelssen, K. s. R. Arndt Min Jou, W., J. Merregaert, R. Contreras, F. Duerinck,

G. Haegeman, A. Raeymaekers, G. Volckaert, M . Ysebaert and W. Fiers, Bacteriophage MS2 RNA: nucleotide sequence determination of the A protein gene 1231*

Miosga, V. s. P. Schmialek Mishin, V., I . Tsyrlov, O. Gromova and V. Lyakhovich,

Phospholipids as cinchocaine action site during inhibition of lipoperoxidative reactions in rat liver microsomes 626

Misra, P. C. and M . Höfer, On the concept of a H®-sugar symport in eukaryotes 1231*

Mönkemeyer, H. and E. Bermek, Inactivation of human ribosomes by N-ethylmaleimide 26

Mönkemeyer, H. s. U . Ücer Moens, L. s. M. Kondo Mohar, O. s. A. Goffeau Mohn, G. und E.-M. Philipp, Zeitlicher Verlauf der

Induktion des Hydroxylasesystems der Mäuseleber-mikrosomen durch Cyclohexan und eine geeignete Bezugsgröße für Hydroxylaseaktivitäten 564

Molen, H . J. van der s. W. M . O. van Beurden Molitor, H . , D. Drahovsky and A. Wacker, Autoradio­

graphic pattern of labelled DNA double helices produced by secondary photo emission 1232*

Molitor, H . , D. Drahovsky and A. Wacker, Distribu­tion of 5-methylcytosine in chromosomal D N A of mouse L fibroblasts as revealed by D N A fibre auto­radiography 1232*

Molitor, H . s. D. Drahovsky Moog, P. und K. Krisch, Versuche zur Reinigung und

Charakterisierung der Atropinesterase aus Kanin-chenlebermikrosomen 529

Moser, H . s. D. Schneider Mosselmans, R. s. J. C. Wanson Mraz, W. and H . Jatzkewitz, Cerebroside sulphatase

activity of arylsulphatases from various invertebrates 33

Mühlhäuser, J. s. R. Ghraf Müller, O.-A. s. J. Huber Müller, P. K., W. N . Meigel,B. F. PontzandK. Raisch,

Influence of aX-dipyridyl on the biosynthesis of collagen in organ cultures 985

Müller-Enoch, D. , H . Thomas and P. Holzmann, Metabolism of 3,4-dimethoxyphenyl compounds in rat liver 1232*

Müller-Ruchholz, E. R. s. H . Reinauer Müllhofer, G. and C. Gleißner, Quantitative evaluation

of the interaction between the pathway of gluco­neogenesis and the tricarboxylic acid cycle in isola­ted rat liver parenchymal cells 1233*

Müllhofer, G., E. Loy, P. Wollenberg and R. Krämer, A possible role of the glycerol phosphate cycle in cyclic AMP-stimulated gluconeogenesis from lactate in perfused rat livers 239

Mulder, E. s. W. M . O. van Beurden Muthiah, P., H . W. Stuhlsatz and H.Greiling, Com­

position of corneal proteoglycans: Density gradient centrifugation and chromatographic studies 924

Nachmansohn, D., Integral model of nerve excitability, I . Biochemical foundation of the integral model 111 *

Nahler, G. s. Ch. Bieglmayer Nattero, G. s. E. Nowotny Neubert, D. s. R. Krowke Neuhoff, V., A. Behbehani, C-D. Quentin and H . Prinz,

Identification by dansylation of 5-hydroxytrypto-phan in the cerebro-spina! fluid of children with phenylketonuria 891

Neuhoff, V. s. P. Fuchs Neuhoff, V. s. R. Rüchel Neuhoff, V. s. D. I . Wolfrum Neumann, E., Integral model of nerve excitability,

I I . Physico-chemical control of nerve excitability 111*

Neupert, W., Cooperation of mitochondrial and cyto­plasmic protein synthesis in the formation of the mitochondrial membrane 1234*

Neupert, W. s. G. Hallermayer Niall, H . D. s. G. W. Tregear Nie, R. van s. M . Sluyser Niemeyer, I . s. W. Lorenz Nijweide, P. J., Calcium transport in bone cells 1235* Nittinger, J., W. Romen, E. Janson and G. Siebert,

Production and properties of sodio-tolerant L cells 761

1664 Autorenverzeichnis Bd. 355 (1974)

Nordmeyer, J.-P. s. R. D. Walter Nordwig, A. s. A. Stemberger Norpoth, K. , H . Bösenberg, U. Witting, P. Kruse und

S. Grass, Spektophotometrische Messungen zur Bindung des Aflatoxin B x an Lebermikrosomen der Ratte 867

Nowotny, E., R. D. Sananez, G. Nattero, C. Yantorno and M . G. Faillaci, Bioconversion of steroids in vitro by testes from autoimmunized rabbits 716

Nündel, M . s. P. Schmialek Nudel, U . s. G. Huez Nyns, E. J. s. J. M . Delaisse

Obermeyer, J . s. F. Heinz O'Brien, J. F., J. Spranger and M . Cantz, The defect in

Maroteaux-Lamy disease (mucopoly-saccharidosis V I , subtype A) : Deficiency of TV-acetylgalactos-amine-4-sulfatase 1235*

Oesterhelt, D., Vergleichende Aspekte der Photorezep­tion von Retinal-Protein-Komplexen 101*

Ohlenschläger, G. s. G. Zimmer Oldenkott, P. s. J. Hausdörfer Ooms, H. s. D. Bernaert Oostveldt, P. van s. G. Boeken O'Riordan, J. L. H . s. G. W. Tregear Ortin, J., K. M . Scheidtmann and W. Doerfler, Studies

on the transcription of adenovirus type 12 1235* Osanai, M . und H . Rembold, Biosynthese von Cyto-

chrom c, IV: Entwicklungsabhängige Aktivitätsän­derungen von 5-Aminolävulinat- und Porphobili­nogen-Synthase bei der Honigbiene 327

Osterrieth, P. M . , F. Rentier-Delrue, C. M . Calberg-Bacq and L. Dierickx, Purification and properties of the replicative form of Semliki Forest virus ribonucleic acid 1236*

Osterrieth, P. M . s. C. M . Calberg-Bacq Ottnad, M . s. G. Jung Otto, K. s. Y. Eeckhout Overdijk, B., W. A. Veitkamp and G. J. M . Hoogh-

winkel, Properties of the three multiple forms of ß-/V-acetylglucosaminidase in human brain tissue 1236*

Pai, S. H. s. M . Hirsch-Kauffmann Palm, W., Über die physikalisch-chemische Charakteri­

sierung und nachfolgende Kristallisation von Im­munglobulinen und deren Fragmenten: Ein Beitrag zur dreidimensionalen Strukturaufklärung der Anti­körper, I : Die humane Immunglobulin L-Kette Rei., ein Bence-Jones-Protein vom x-Typ, Sub-gruppe I 872

Palm, W., Über die physikalisch-chemische Charakteri­sierung und nachfolgende Kristallisation von Im­munglobulinen und deren Fragmenten: Ein Beitrag zur dreidimensionalen Strukturaufklärung der Anti­körper, I I : Das humane Immunglobulin Kol . : Ein Myelom-Protein der Klasse IgG, a,x 2, Gm(f)® 877

Palmowski, B. und L. Träger, Umwandlung von 3ß-Hydroxy-5-pregnen-20-on (Pregnenolon) durch Streptomyces hydrogenans 1070

Panitz, N . s. J. Hoppe Paradies, H . H. , D. E. Kuckuk, G. Klotz, H . Zerban

and E. Deusser, Studies on the crystallization of Escherichia coli ribosomes 1557

Parsons, J. A. s. G. W. Tregear Passow, H. s. J. H . Kaplan Patzelt, R., H . Pauls, E. Erdmann and W. Schoner,

Study of (Na® + K©)-ATPase with ATP-analogues 758*

Patzelt, R., H. Pauls and W. Schoner, Study of (Na® + K®)-ATPase with 6-chloropurine triphosphate, 6-mercaptopurine triphosphate and dinitrophenyl-6-thiopurine triphosphate 1237*

Pauls, H. s. R. Patzelt Peiler-Ichikawa, K. s. H . Woelk Penasse, W. s. D. Bernaert Penasse, W. s. C. May Peters, H . H. , B. Jung, A. Boie and W. Seubert, Regu­

lation of hepatic and renal gluconeogenesis at the pyruvate/phosphoenolpyruvate level by lysine, orni­thine and glutamine 1237*

Pette, D. s. G. Dölken Pfaff, E. s. H. Baur Pfaff, E. s. R. Burr Pfeiffer, E. F. s. H . Etzrodt Pfeiffer, E. F. s. V. Maier Pfeuffer, T. and R. Thomas, Stimulation of adenylate

cyclase from avian erythrocyte membranes by GTP analogs. Separation and partial purification of a GTP-binding protein 1237*

Pfleiderer, G., A. L. Dikow und F. Falkenberg, Quanti­tative Bestimmung genetisch determinierter Iso­enzyme mittels Immuntitration. Verteilungsmuster der Aldolase A, B und C in menschlichen Organ-und Gewebsextrakten sowie in normalen und patho­logischen Seren 233

Pfleiderer, G. s. M . Boll Philipp, E.-M. s. G. Mohn Pietrzyk, C , a-Aminoisobutyric acid uptake by meta­

bolizing, K®-deficient mouse Ehrlich ascites tumor cells 1238*

Pittner, F., W. Fried and O. Hoffmann-Ostenhof, Studies on the biosynthesis of cyclitols, X X X : Puri­fication of myö-inositol-l-phosphate synthase of rat testes to homogeneity by affinity chromatography on NAD-sepharose 222

Planta, R. J. s. J. van't Riet Podack, E. R. s. W. Seubert Poensgen, J. and V. Ullrich, The binding of cytochrome

b5 to liposomes 1238* Pollow, B. s. K. Pollow Pollow, K. , G. Sokolowski, H . Grunz und B. Pollow,

Hydroxysteroid-Oxidoreduktasen und ihre Funktion als Katalysatoren des spezifischen Wasserstoff-Transfers zwischen Steroidhormonen in Human-

Bd.355 (1974) Autorenverzeichnis 1665

Placenta, I . Morphologische Untersuchungen und Aktivitätsverteilungen der 17ß- und 20a-Hydroxy-steroid-Oxidoreduktase in subzellulären Fraktionen 501

Pollow, K., G. Sokolowski, J. Schmalbeck und B. Pol-low, Hydroxysteroid-Oxidoreduktasen und ihre Funktion als Katalysatoren des spezifischen Wasser­stoff-Transfers zwischen Steroidhormonen in Hu­man-Placenta, I I . Kinetische Untersuchungen und Wasserstoff-Transfer zwischen C-l7 von Oestradiol-17ß und C-20 von Progesteron 515

Pongs, O. s. R. Bald Pongs, O. s. E. Lanka Ponta, H. s. M . Hirsch-Kauffmann Pontz, B. F. s. P. K. Müller Popowski, A. s. J. C. Wanson Porcellati, G. s. H. Woelk Pott, G., W. Henkel und E. Werries, Stereospezifischer

enzymatischer Abbau von Glucopyranosyl-galakto-pyranosyl-hydroxylysin aus Aortenkollagen 787

Potts, J. T., Jr. s. G. W. Tregear Preaux, G. and H. Dekoster, Fluorescence of ß-lacto-

globulin B as a function of pH before and after blocking of the thiol groups with organomercurials 1238*

Prinz, H . s. V. Neuhoff Probst, H . s. G. Jung Puschendorf, B., D. Böhlandt and H . Grunicke, Effect

of distamycin A on T4-DNA-directed RNA synthe­sis 1239*

Quad flieg, K. -H. and K. Brand, Xylitol metabolism in human erythrocytes 1239*

Quentin, C.-D. s. V. Neuhoff Querinjean, P. s. V. Starace

Rabe, T. N . s. U . Hilgenfeldt Raeymaekers, A. s. W. Min Jou Rafael, J., G. Wiemer, H.-J. Hohorst and W. Burck-

hardt, Mitochondria from brown adipose tissue: Influence of albumin, guanine nucleotides and of substrate level phosphorylation on the internal ade­nine nucleotide pattern 341

Raftery, M . A., Characterization of acetylcholine recep­tors 112*

Raftery, M . A. s. J. Bode Rahmsdorf, H.-J. s. M . Hirsch-Kauffmann Raisch, K. s. P. K. Müller Rao, G. S., M . L. Rao, G. Haueter and H . Breuer,

Steroidglucuronytransferases, V: Formation and hydrolysis of oestrogen glucuronides by the liver, kidney and intestine of the pig 881

Rao, G. S. s. M . L. Rao Rao, M . L., G. S. Rao, M . Höller and H . Breuer, Up­

take of Cortisol by isolated rat liver cells 1239* Rao, M . L. s. G. S. Rao

Rauen, H . M . s. J. Lohmann Rauenbusch, E. s. C. Kutzbach Reber, K. s. P. C. Heinrich Rehberger, G. s. W. E. Merz Reiber, H . , a,ß-Elimination of serine: mechanism and

catalysis of a model reaction and the consequences for the active centre of serine dehydratase 1240*

Reif, U . , U . Winterhoff, M . Westphal and W. Doerfler, Purification and characterization of an endonuclease from adenovirus-infected cells 1240*

Reimer, G., D. Drahovsky and A. Wacker, Synthesis of RNA and DNA in isolated chromosomes of Pseudomonas testosteroni 1240*

Reinauer, H. , Regulation of the pyruvate dehydro­genase complex in mammary tissue of the rat 1241*

Reinauer, H . and E. R. Müller-Ruchholz, Regulation of the pyruvate dehydrogenase complex in perfused hearts of guinea pigs 1241*

Reinking, A. s. P. Boer Reinking, A. s. H . J. M . van Rijn Rembold, H . s. M . Osanai Renner, R., W. Kemmler and R. Anding-Edel, Mecha­

nism of the increased biological activity of turkey insulin 1555

Renner, R., H . J. Kolb and K. D. Hepp, Critical eva­luation of sepharose-coupled insulin as a tool for studies of insulin action at the membrane level 1242*

Renner, R. s. W. Kemmler Renooij, W. and L. M . G. van Golde, Preferential in­

corporation of fatty acids at the inside of human erythrocyte membranes 1242*

Rentier-Delrue, F. s. C. M . Calberg-Bacq Rentier-Delrue, F. s. P. M . Osterrieth Resch, K. s. G. Brunner Reuvers, F. s. P. Boer Revel, M . s. G. Huez Richter, D. s. V. A. Erdmann Riedel, B. s. J. Sonnenbichler Rieke, E. s. J. Hoppe Riet, J. van't, J. H . van Ee and R. J. Planta, The respi­

ratory nitrate reductase of Klebsiella aerogenes: Composition and the role of metal groups 1243*

Rietschoten, J. van s. G. W. Tregear Rijn, H . J. M . van, P. Boer, A. Reinking and E. P.

Steyn-Parve, On the biosynthesis of the acid phos­phatase: studies on a fraction containing precursors of the extracellular enzyme 1243*

Rijn, H . J. M . van s. P. Boer Ring, K., R. Tobias and H . Ehle, Effect of adenosine

3' ̂ '-monophosphate on active amino acid trans­port in Streptomyces hydrogenans 1243*

Ring, K. s. S. Alim Risse, H.-J. s. H . Rogge Robbers, G., H . Fürniss und H . Debuch, Über die

Bildung der Plasmalogene zur Zeit der Myelinisie­rung bei der Ratte, V I I : Einbau von Natrium-[l- 1 4C] acetat in die Aldehyde und in die Sphingosinbasen zu verschiedenen Zeiten 557

1666 Autorenverzeichnis Bd. 355 (1974^

Roberfroid, M . , G. Dubois, O. Gravier, M . J. Yerna, J. Cumps and M . Mercier, Biochemical properties of isolated adult rat hepatocytes. Subscellular frac­tionation and enzymatic latency 1244*

Robert, B. s. J. Hoshino Röhle, G. and H . Breuer, Synthesis of glucuronides of

2-hydroxylated oestrogens and their methyl ethers 490

Röhm, K.-H. , Properties of a highly purified dipepti-dase (EC 3.4.13.?) from brewer's yeast 675

Röhm, K.-H. s. G. Metz Rogge, H . and H.-J. Risse, Glycosyltransferases in

membraneous and nuclear fractions of Dictyostelium 1244*

Rogge, H . and H.-J. Risse, A procedure for the isola­tion of Dictyostelium nuclei 1467

Romen, W. s. J. Nittinger Rooijen, P. J. van s. S. Visser Ruddle, F. H . s. K. Willecke Rudland, P. S. s. W. Seifert Rudloff, E. and K. Hilse, Isoaccepting lysyl-, glutamyl-

and glutaminyl-tRNA from rabbit liver and reti­culocytes: Coding properties, inactivation by iodine and cell-free protein biosynthesis 1245*

Rübsamen, H . , R. Khandker and H. Witzel, Sigmoid kinetics of the monomelic ribonuclease I due to ligand induced shifts of conformation equilibria 687

Rüchel, R., S. Mesecke, D.-I . Wolfrum and V. Neuhoff, Microelectrophoresis in continuous Polyacrylamide gradient gels, I I . Fractionation and dissociation of sodium dodecylsulfate protein complexes 997

Rüchel, R. s. D. I . Wolfrum Ruf, H. H . s. D. Mansuy Ruis, H. s. Ch. Bieglmayer Rullkötter, J. s. E. Heinz Rummel, W. s. H . Huebers Rupprecht, A. s. W. G. Guder Ryan, R. J. s. H. T. Keutmann

Saathoff, G. s. W. Seubert Sagarra, M . R. de s. P. Walter Salomon, R. s. G. Huez Samsel, W., G. Fischer, R. Kovar and N . E. Fusenig,

The effects of the tumor-promoting agent 12-tetra-decanoyl-phorbol 13-acetate on proliferation and differentiation in primary cultures of mouse epi­dermal cells 1245*

Sananez, R. D. s. E. Nowotny Sandermann, H . Jr., Reversible inhibition of E. coli

D-galactoside transport protein (y-gene product) by urea and by aprotic solvents 1246*

Sandow, J. s. R. Geiger Sarre, Th. and K. Hilse, Methionine transfer into inter­

nal protein positions by isoaccepting Met-tRNA species from rabbit reticulocytes and E. coli 1246*

Sauer, H. W. s. A. Hildebrandt

Sauermann, G., Über die Phosphofructokinase-Rück-reaktion in Aszites-Tumorzellen 459

Sauermann, G., Zur Kinetik der 6-Phosphofructo-kinase-Rückreaktion 1058

Schachtschabel, D. O. and H. Leising, Growth pattern, melanin synthesis, production of lactate, pyruvate and alanine by 2 lines of Harding Passey melanoma cells in culture 1246*

Schachtschabel, D. s. E. Kohen Schäfer, G., Surface potential and ion fluxes through

mitochondrial membranes and phospholipid bilayers 1247*

Schaich, E. und Fr. Schneider, Synthese einer Partial-sequenz aus dem aktiven Zentrum der Streptokok­ken-Proteinase, T 939

Schaich, E. und Fr. Schneider, Synthese einer Partial-sequenz aus dem aktiven Zentrum der Streptokok­ken-Proteinase, I I 945

Schaich, E. und Fr. Schneider, Synthese einer Partial-sequenz aus dem aktiven Zentrum der Streptokok­ken-Proteinase, I I I 952

Schally, A. V. s. R. Geiger Schaper, R. s. W. Gielen Scharmann, W. und E. Balke, Untersuchungen über

eine Protease (Elastase) von Pseudomonas aerugi­nosa, 1: Bildung und Reinigung der Protease 443

Scharmann, W. s. E. Balke Schärpe, S. s. W. Cooreman Schauer, R. s. J. Jancik Scheidtmann, K. M. s. J. Ortin Scheit, K. H . , und A. M. Frischauf, Affinitätsmarkie­

rung von E.-co//-RNA-Polymerase durch Substrat-und,,Templates-Analoge 759*

Schell, P. L., Uptake of ribopolynucleotides by mam­malian cells; the effect of defined alterations of charge and molecular structure of the outer cellular membrane 1247*

Scherer, G., H . Weber und W. Weis, Trägergebundenes Cytochrom b5 als Substrat für die Ascorbat: Ferri-cytochrom-65-Oxidoreduktase aus Säugetierleber-mikrosomen 1350

Schermutzki, W. s. A. Wollmer Schiebel, W. and U. Schneck, DNA replication con­

tinued in isolated nuclei of synchronously growing Physarum polycephalum 1515

Schiefer, H.-G., U . Gerhardt and H. Brunner, Immuno­logical studies on the localization of phosphatidyl-glycerol in mycoplasma membranes 1248*

Schiefer, H.-G., U.Gerhardt, H . Brunner and M . Krüpe, Studies with lectins on the surface car­bohydrate structures of mycoplasma membranes 1248*

Schill, W.-B., The influence of glycerol on the extracta-bility of acrosin from human spermatozoa 225

Schill, W.-B. and G. L. Haberland, Kinin-induced enhancement of sperm motility 229

Schimassek, H . s. H . W. Heidt Schimassek, H . s. A. K. Walli

Bd. 355 (1974) Autorenverzeichnis 1667

Schimz, K.-L., D. Lessmann and G. Kurz, Aspects of regulation of the pathways for D-glucose 6-phos-phate, D-galactose and L-arabinose in Pseudomonas fluoiescens 1249*

Schindler, P. R. G. and M . Teuber, Fluorescent label­ling with 5-dimethyl-aminonaphthalene-l-sulfonyl chloride of membrane surface proteins of gram-negative bacteria 1249*

Schirmer, H . s. G. Zimmer Schlenker, S. s. H . Kraus Schleuning, W. D. and H . Fritz, Some characteristics

of highly purified boar sperm acrosin 125 Schleyer, M. , K.-H. Voigt and H . Etzrodt, Preparation

of porcine growth hormone 1291 Schleyer, M . s. H. Etzrodt Schlimme, E. and K.-W. Stahl, The use of modified

adenine nucleotides in studies of mitochondrial translocation 759*

Schlimme, E. and K.-W. Stahl, Activity of 8-C-bromo-derivatives of ATP and ADP in the mitochondrial adenine nucleotide translocation system 1139

Schlimme, E. s. J. Lüstorff Schmal, A. s. W. Lorenz Schmalbeck, J. s. K. Pollow Schmalreck, A. F. and M . Teuber, Structural features

determining the antibiotic potencies against Bacillus subtilisof the membrane active hop bitter resins 1250*

Schmialek, P., A. Geyer, V. Miosga, M . Niindel and B. Zapf, Juvenile hormone-binding macromolecules in insect organs 1250*

Schmidt, M . F. G., R. T. Schwarz and C. Scholtissek, Metabolism of 2-deoxy-D-glucose in tissue culture cells 1250*

Schmidt, G. s. W. Vogt Schmidt, U. s.W. G. Guder Schmidt, W. and K. Havemann, Isolation of elastase-

like and chymotrypsin-like neutral proteases from human granulocytes 1077

Schmidt, W. and K. Havemann, Isolation and charac­terization of neutral proteases from human neutro­phil granulocytes 1251*

Schmitt, J. M . and R. G. Herrmann, DNA synthesis in isolated chloroplasts 1251*

Schmitt, J. M . s. H . J. Bohnert Schmucker, P. s. R. Elbers Schneck, U. s. W. Schiebel Schneider, D., H . Moser and D. Falke, Influence of

concanavalin A on nucleic acid and protein synthe­sis in growing baby hamster kidney 21 cells 1251*

Schneider, Fr. s. H. P. Krause Schneider, Fr. s. H . G. Löffler Schneider, Fr. s. G. Metz Schneider, Fr. s. E. Schaich Schneider, M . und N . Hilschmann, Die Primärstruktur

einer monoklonalen Immunglobulin-L-Kette der Subgruppe IV vom x-Typ (Bence-Jones-Protein Len.): eine neue Subgruppe der L-Ketten vom x-Typ 1164

Schneider, Y. J., A. Trouet and P. Tulkens, Uptake and intracellular fate of anti-plasma membrane antibodies in cultured fibroblasts 1252*

Schönharting, M . , G. Mende and G. Siebert, Metabolic transformation of colchicine, I I : The metabolism of colchicine by mammalian liver microsomes 1391

Schoelkens, B. s. H . Wissmann Schölte, H. R. s. P. H . E. Groot Scholtissek, C. and J. Dämmgen, Specific inhibition of

influenza and Semliki Forest virus RNA synthesis by glucosamine 1252*

Scholtissek, C. s. M . F. G. Schmidt Schoner, W. s. R. Patzelt Schonne, E. s. J. C. Mareschal Schorn, K. s. K. Hochstraßer Schorp, G. s. H. Jering Schramm, H . J. s. W. Hoppe Schreiber, E. s. W. Stoffel Schriefers, H . s. R. Ghraf Schriefers, H. s. E. R. Lax Schriewer, H . s. J. Lohmann Schröder, E. s. E. R. Lax Schröder, J. and K. Hahlbrock, Comparison in vivo

and in vitro of specific, light-induced changes in the rates of protein synthesis in cell suspension cultures of Petroselimtm hot tense 1253*

Schubert, D., S. Ehrenspeck and K. U. Berger, Protein-lipid and protein-protein interactions in recombined lipoprotein membranes 1253*

Schürrle, L. s. W. Kochen Schulz, G. s. H.-W. Vohland Schulze, P. E. s. H.-W. Vohland Schumacher, G. and R. Ehring, Effect of different con­

formations of gal mRNA on enzyme expression and messenger half-life in RNA-directed cell-free en­zyme synthesis 1253*

Schwab, D. s. M . Gratzl Schwarz, R. T. and H.-D. Klenk, Inhibition of glyco-

sylation of the influenza virus hemagglutinin 1254* Schwarz, R. T. s. M. F. G. Schmidt Schwarz, U. s. H. G. Gassen Schwedesky, D. s. H . Kraus Schweiger, M . s. M. Hirsch-Kauffmann Schwenen, M. , F. Skov and W. Staib, Combined per­

fusion of liver and hindquarter from the rat: a model in vitro for investigation of hormonal control of metabolism 1254*

Schwenen, M . s. Chr. Funke Schwenk, M . s. R. Burr Sebald, W. s. G. Jackl Seglen, P. O., Carbohydrate metabolism of isolated

parenchymal rat liver cells 1255* Seifart, K. H . s. B. J. Benecke Seifert, W. and P. S. Rudland, Cyclic GMP, guanyl

cyclase and growth control 1255* Seitz, U . s. H . Arnold Sekeris, C. E. s. H . Bojar Sekeris, C. E. s. E. G. Fragoulis

1668 Autorenverzeichnis Bd. 355 (1974)

Seubert, W., E. R. Podack and G, Saathoff, Mechanism of microsomal chain elongation of fatty acids 1255*

Seubert, W. s. W. Hinsch Seubert, W. s. W. Huth Seubert, W. s. H . H . Peters Seubert, W. s. B. Stumpf Sick, H . and K. Gersonde, Comparative studies on the

CO binding of Hb A and mutants 1256* Siebert, G. s. J. Nittinger Siebert, G. s. M . Schönharting Siebler, G. s. A. K. Walli Siekmann, L. s. H.-O. Hoppen Sies, H . , Appendix. Absorbance difference spectrum

of perfused rat liver in the presence of ammonium chloride or ethanol in the near-ultraviolet region 319

Sies, H . and D. Häussinger, Lack of urea formation by rat liver in hydrogen carbonate-free media 1256*

Sies, H . , D. Häussinger, and M . Grosskopf, Mito­chondrial nicotinamide nucleotide systems: Ammo­nium chloride responses and associated metabolic transitions in hemoglobin-free perfused rat liver 305

Simon, D. s. J. Hoshino Simon, B. s. H . Kather Singh, S., I . Willers and H . W. Goedde, A micro-

method for the assay of purine phosphoribosyl transferases in cultured human fibroblasts and amniotic cells 1257*

Sinterhauf, K. , P. Herzog and D. Lommer, Studies in vitro on corticosteroid synthesis in human adrenals 1257*

Skov, F. s. M . Schwenen Siegers, H . s. M . Kondo Sluyser, M . and R. van Nie, Oestrogen receptor content

and hormone-responsive growth of mouse mam­mary tumours 1257*

Soboll, S. s. R. Elbers Sokolowski, G. s. K. Pollow Sonnenbichler, J. and B. Riedel, Concerning chromatin

subunits 1477 Soreq, H . s. G. Huez Spaczynski, K. s. P. Back Spangenberg, P. s. R. Kleine Spener, F., A model system for the biosynthesis of

cyclopentenyl fatty acids 1258* Spranger, J. s. J. F. O'Brien Sprinzl, M . and F. Cramer, On the structure of the CCA

end of t R N A P h e from yeast 753* Sprinzl, M . s. V. A. Erdmann Srivastava, B. s. J. de Lafonteyne Srivastava, L. M . , L . Datta and G. P. Talwar, Early

effect of estradiol-17ß on glycogen, alkaline phos­phatase and acid phosphatase of the various cells of rat uterus 1259*

Srivastava, L. M . , D. P. Agarwal and H . W. Goedde, Serum lactate dehydrogenase and other enzymes in different forms of leprosy 1258*

Stahl, J. s. W. Stoffel Stahl, K.-W. s. E. Schlimme

Staib, W. s. K. Balzer Staib, W. s. H . Bojar Staib, W. s. Chr. Funcke Staib, W. s. W.-D. Hetzel Staib, W. s. M . Schwenen Starace, V., P. Querinjean, H . Bazin, A. Beckers, M .

Manteuffel and F. J. Heremans, The complete amino acid sequence of a ratx-light chain 1259*

Stark, G. s. E. Bamberg Staudinger, Hj . s. S. W. Golf Stemberger, A. and A. Nordwig, Invertebrate collagens:

Qualitative and quantitative studies on their carbo­hydrate moieties 721

Stevens, E. A. M . s. M . Joniau Steyer, M . s. Chr. Funcke Steyn-Parve, E. P. s. P. Boer Steyn-Parve, E. P. s. H . J. M . van Rijn Stieve, H . , On the ionic mechanisms responsible for

the generation of the electrical response of light sensitive cells 101*

Stöffler, G. s. A. P. Czernilofsky Stoffel, W., E. Bauer and J. Stahl, The metabolism of

sphingosine bases in Tetrahymena pyriformis. Sphin-gosine kinase and sphingosine-1-phosphate lyase 61

Stoffel, W. and K. Bister, Studies on the desaturation of sphinganine. Ceramide and sphingomyelin meta­bolism in the rat and in BHK 21 cells in tissue cul­ture 911

Stoffel, W. and W. Därr, 2-Alkenal reductase: Isola­tion, properties and specificities 54

Stoffel, W. and G. Heimann, The action of lysosomal lipolytic enzymes on alkylether-containing phospho­lipids 651

Stoffel, W., B. D. Tunggal, O. Zierenberg, E. Schreiber and E. Binczek, 1 3 C-NMR studies of lipid inter­actions in one- and multi-component lipid vesicles 1367

Stoffel, W., O. Zierenberg, B. D. Tunggal and E. Schrei­ber, 13C-Nuclear magnetic resonance spectroscopic studies on lipid-protein interactions in human high density lipoprotein (HDL); a model of the H D L particle 1381

Stone, P. R., R. Bredehorst, M. Kittler and H. Hilz, Quantitative determination of poly (ADP-ribose) in mammalian cells 1259*

Ströder, W. and H . Hörmann, Dissociable aggregates and non-dissociable oligomers in cryofibrinogen of human plasma 776

Strosberg, A. D. s. G. Vauquelin Stuhlsatz, H . W. s. P. Muthiah Stumpf, B., A. Boie, H . Leimcke and W. Seubert, On

the mechanism of gluconeogenesis and its regulation, V I I I : Differentiation of regulatory attacks of gluco­corticoids, L-lysine and cyclic AMP in renal gluco­neogenesis 205

Sturm, M . s. W. Hoppe Sures, I . s. D. Gallwitz

Bd. 355 (1974) Autorenverzeichnis 1669

Tager, J . M. s. J. R. Williamson Takesue, S. s. K. Watanabe Talwar, G. P. s. L . M . Srivastava Tan, I . s. U . Guntermann Tencheva, Z. S., K. Kanig and H . Woelk, Electropho-

retic characteristics of neuronal and glial RNA from rat brain 1260*

Teuber, M . s. P. R. G. Schindler Teuber, M . s. A. F. Schmalreck Thauer, R. and G. Fuchs, Carbon monoxide oxidation

by anaerobic bacteria: indications for the involve­ment of a vitamin B1 2-compound 1260*

Thauer, R. s. G. Fuchs Thermann, M . s. W. Lorenz Thielmann, H . W. and H . P. Vosberg, Carcinogen-

induced D N A repair 1260* Thomas, H . s. D. Müller-Enoch Thomas, R. s. T. Pfeuffer Thomitzek, W.-D., Activation of external carnitine

palmitoyltransferase in rat heart mitochondria 1261 * Thorell, B. s. E. Kohen Thurm, U . , Mechanismen elektrischer Membranreak­

tionen in Sinneszellen 102* Thurman, R. G. and W. McKenna, Activation of

ethanol utilization in perfused liver from normal and ethanol-pretreated rats. The effect of hydrogen peroxide generating substrates 336

Tio, T. H . s. H . G. van Eijk Tjiong, H.-B. s. R. Kannan Tobias, R. s. K. Ring Tol, A. van, Isoenzymes of fructosediphosphatase in

small intestinal epithelium 1261* Torrence, P. F. s. E. de Clercq Traber, J., K. Fischer, S. Latzin and B. Hamprecht,

Cultures of cells derived from the nervous system: synthesis and action of prostaglandin E 1262*

Träger, L . s. J. Betz Träger, L. s. C. Markert Träger, L. s. B. Palmowski Trautschold, I . s. J. Freise Tregear, G. W., J. van Rietschoten, E. Greene, H . D.

Niall, H . T. Keutmann, J. A. Parsons, J. L. H . O'Riordan and J. T. Potts, Jr., Solid-phase synthesis of the biologically active N-terminal 1 - 34 peptide of human parathyroid hormone 415

Trouet, A. s. Y. J. Schneider Tschesche, H . s. H . Jering Tsyrlov, I . s. V. Mishin Tulkens, P. s. Y. J. Schneider Tunggal, B. D. s. W. Stoffel Tzagoloff, A. s. A. Goffeau

Ücer, U . , H . Mönkemeyer and E. Bermek, Studies on proteins from human tonsillar cytoplasmic ribo­somes 1262*

Ücer, U . s. E. Bermek

Ulbricht, W., Drugs to explore the ionic channels in the axon membrane 104*

Ullrich, V. s. W. Düppel Ullrich, V. s. D. Mansuy Ullrich, V. s. J. Poensgen Unnewehr, M . s. H . Bojar

Vaes, G. s. Y. Eeckhout Vandalem, J. L . s. G. Maghuin-Rogister Van de Voorde, A. s. G. Volckaert Vauquelin, G., M.-L. Lacombe, J. Hanoune and A. D.

Strosberg, Rat liver adenylate cyclase activation by azoderivatives of catecholamines 1263*

Veitkamp, W. A. s. B. Overdijk Verbist, L . s. M . Joniau Verdonk, G. s. A. Christophe Verhoef, N . J., Iron transport through the plasma mem­

brane of immature red blood cells 1263* Veronese, F. M . s. A. Fontana Vetter, U . s. R. Ghraf Visser, S. and P. J. van Rooijen, Synthetic substrates

for chymosin (rennin) 1264* Voelter, W. and H . Horn, Synthese von [Tyr(OMe) 2]

Thyroliberin, einem neuen Analogon des Thyro-tropin-freisetzenden Hormons 1466

Vogt, H.-P. s. A. Wollmer Vogt, W., L. Dieminger, R. Lynen and G. Schmidt,

Alternative pathway for the activation of comple­ment in human serum. Formation and composition of the complex with cobra venom factor that cleaves the third component of complement 171

Vohland, H.-W., P. E. Schulze, W. Koransky, G. Schulz und B. Acksteiner, Stoffwechsel von Pentetrazol bei der Ratte: Isolierung und Identifizierung der Haupt-metaboliten aus dem Urin 1274

Voigt, K.-H. s. M . Schleyer Volckaert, G., A. Van de Voorde and W. Fiers,

Nucleotide sequence analysis of the SV40-hind H DNA fragment 1264*

Volckaert, G. s. W. Min Jou Voorthuizen, W. F. van s. B. N . Bachra Vormbrock, R. s. H. G. Gassen Vosberg, H . P. s. H . W. Thieland Vutz, H . s. C. Woenckhaus

Wacker, A. s. D. Drahovsky Wacker, A. s. H . Krippner Wacker, A. s. H . Molitor Wacker, A. s. G. Reimer Wagner, K. s. R. H . Ackermann Wagner, K. G. s. J. Hoppe Wagner, T. s. V. A. Erdmann Wald, G., Visual pigments and retinal excitation 99* Walli, A. s. H . Faulstich Walli, A. K., K. Birkmann and H . Schimassek, Glyco­

gen metabolism in isolated rat liver parenchymal cells 1264*

1670 Autorenverzeichnis Bd. 355 (1974)

Walli, A. K. , G. Siebler, E. Zepf and H . Schimassek, Gly­cogen metabolism in isolated perfused rat liver 353

Walli, A. K. s. H . W. Heidt Wallner, O. and H . Fritz, Characterization of an acid-

stable proteinase inhibitor in human cervical mucus 709

Walsch, S. s. E. Degkwitz Walter, P., P. Fasel and M . R. de Sagarra, Effects of

glucagon, insulin, adrenalin and cycloheximide on glucose metabolism in isolated rat liver parenchymal cells 1265*

Walter, R. D., S'^'-Cyclic AMP phosphodiesterase from Trypanosoma gambiense 1443

Walter, R. D. and E. Königk, Biosynthesis of folic acid compounds in Plasmodia: Purification and proper­ties of the 7,8-dihydropteroate-synthesizing enzyme from Plasmodium chabaudi 431

Walter, R. D., J.-P. Nordmeyer and E. Königk, Adeny­late cyclase from Trypanosoma gambiense All

Walter, R. D., J.-P. Nordmeyer and E. Königk, NADP-specific glutamate dehydrogenase from Plas­modium chabaudi 495

Wanka, F., Effect of 2,4-dinitrophenol on DNA syn­thesis in bovine liver cells in vitro 1265*

Wanson, J. C , P. Drochmans, A. Popowski and R. Mosselmans, Hepatocytes from adult rats in mono­layer culture: ultrastructural aspects and enzymat functions related to glycogen metabolism 1265*

Wanson, J. C. s. C. May Watanabe, K. and S. Takesue, Interaction of some

gaseous hydrocarbons with egg-white lysozyme 184 Wauwe, J. P. van s. F. G. Loontiens Weber, H. , W. Weis und B. Wolf,Monodehydro-L(+)-

ascorbat reduzierende Systeme in unterschiedlich präparierten Schweinelebermikrosomen 595

Weber, H. s. G. Scherer Weber, U . und P. Hartter, Synthese und Stabilität von

cyclischen Disulfiden des Typs Cys-(X),rCys 189

Weber, U. und P. Hartter, Synthese und Stabilität von cyclischen Disulfiden der Struktur Cys-X-Cys-OMe 200 1 •

Weckauf-Bloching, M . s. H . Faulstich Weigand, K., Properties of enzymatically isolated rat

liver cells in the ficoll gradient 1266* Weigand, K. , H . Wernze and C. Falge, Synthesis and

secretion of albumin and angiotensinogen by isola ted rat liver cells 1266*

Weimann, G., Cyclophosphate analogues, chemical preparation and some biochemical properties 755*

Weis, W. s. G. Scherer Weis, W. s. H. Weber Weiss, G. s. C. A. Lamartiniere Weiss, H . s. B. Lorenz Weiss, L. , G. Löffler and O. H . Wieland, Regulation

by insulin of adipose tissue pyruvate dehydrogenase. A mechanism controlling fatty acid synthesis from carbohydrates 363

Wei, H . van der, Thaumatin and monellin, the intensely sweet-tasting proteins from tropical african fruits 107*

Weltzien, H. U. and B. Arnold, Interaction of lysole-cithin analogs with various hydrophobicities with erythrocyte membranes 1267*

Wengler, G. and M . Beato, Characterization of virus-specific mRNA from cells infected with the toga-virus Semliki Forest virus by translation in vitro 1267*

Wenzel, M . , B. Bollert und B. Ahlers, Langsame Disso­ziation des NADH-Dehydrogenase-Komplexes als Ursache für den bevorzugten Wasserstoff-Transfer zwischen Steroiden an C-17 969

Werdan, K. s. H . W. Heidt Werner, D. s. G. Maier Werner, G. s. W. W. Just Werner, S., Precursors of cytochrome oxidase in cyto­

chrome-oxidase deficient cells of Neurospora crassa 1261*

Wernze, H . s. K. Weigand Werries, E. und L. Freßmann, Eine verbesserte Methode

zur quantitativen Trennung und präparativen Dar­stellung von ß-A'-Acetylglucosaminidasen A und B 1479

Werries, E. s. G. Pott Wesemann, W., Biochemistry of serotonin and synaptic

membranes in neurotransmission 112* Westphal, M . s. U. Reif Whittaker, V. P., Aspects of the biochemistry of cho­

linergic transmission in Torpedo and Loligo 111* Wiedemann, H.-R. s. R. Kannan Wiegandt, H. and W. Ziegler, The use of reductamina-

ted sugars for the preparation of oligosaccharide conjugates, I . Synthetic glycolipids containing glyco-sphingolipid-derived oligosaccharides 11

Wiegandt, H. s. T. W. Keenan Wieland, O. H., G. Löffler, S. Bard and 1. Brunner,

Control of pyruvate dehyerogenase interconversion by palmitoyl-coenzyme A as related to inhibition of adenine nucleotide translocation in isolated fat-cell mitochondria 1268*

Wieland, O. H. s. L . Weiss Wieland, Th. s. H . Faulstich Wiemer, G. s. J. Rafael Wienand, U . and E. Fuchs, In vitro transcription by

DNA-dependent RNA polymerase of E. coli at low pH 1268*

Wiese, H . s. R. Elbers Wildfeuer, A. s. R. Ghraf Wilkening, J. and K. Decker, The dependence of the

rate of gluconeogenesis in the isolated perfused rat liver on the adenosine triphosphate content 1268*

Wille, W., E. Eisenstadt and K. Willecke, Inhibition of fatty acid biosynthesis with cerulenin and its effects on citrate-Mg2® transport and macromole-cular syntheses in Bacillus subtilis 1269*

Bd. 355 (1974) Autorenverzeichnis 1671

Willecke, K. and F. H . Ruddle, Transfer of the human gene (HGPRT) for hypoxanthine phosphoribosyl-transferase (EC 2.4.2.8) on isolated human meta-phase chromosomes into mouse cells 1269*

Willecke, K . s. W. Wille Willers, I . s. S. Singh Williamson, J. R., J. A. Gimpel, G. J. DeLeeuw, H . E.

S. J. Hensgens, A. J. Meijer and J. M. Tager, Regu­lation of hepatic urea synthesis 1270*

Wiltink, W. F. s. H . G. van Eijk Winterhoff, U. s. U . Reif Wissmann, H. , B. Schoelkens, E. Lindner und R. Gei­

ger, Chemie und Wirkungsweise neuer Angiotensin-II-Antagonisten: 8-C-Phenylglycin-Analoga des [5-IsoleucinJAngiotensins II 1083

Witassek, F. s. G. Legier Witkop, B. s. E. de Clercq Wittke, B. s. P. Geck Witting, U . s. K. Norpoth Wittliff, J. L. s. H. Bojar Wittmann, H.-G. s. M . Hirsch-Kauffmann Wittmann, H. G. s. A. Yuki Witzel, H . s. H. Rübsamen Wodick, R. and D. W. Lübbers, Quantitative evalua­

tion of reflexion spectra of living tissues 583 Woelk, H . , G. Goracci and G. Porcellati, The action

of brain phospholipases A 2 on purified, specifically labelled 1,2-diacyl-, 2-acyl-l-alk-r-enyl- and 2-acyl-1 -alkyl-.s-//-glycero-3-phosphoryl-choline 75

Woelk, H . , K. Kanig and K. Peiler-Ichikawa, Incorpo­ration of 3 2P into the phospholipids of neuronal and glial cell-enriched fractions isolated from rabbit cerebral cortex. Effect of norepinephrine 1270*

Woelk, H . , K. Peiler-Ichikawa, L. Binaglia, G. Goracci and G. Porcellati, Distribution and properties of phospholipases A x and A 2 in synaptosomes and subsynaptosomal fractions of rat brain 1535

Woelk, H . , K. Peiler-Ichikawa, L. Binaglia and G. Por­cellati, Distribution and properties of phospholipase At and A 2 in synaptosomes and synaptosomal sub-fractions 1270*

Woelk, H . s. Z. S. Tencheva Woenckhaus, Ch., NAD® analogues 756* Woenckhaus, C. and H. Vutz, Covalently bound

nicotinamide riboside diphosphate ester 1271* Wörner, P. and R. Brossmer, Action of ionophores for

divalent cations on human platelets 1271* Wolf, B. s. H. Weber

Wolf, H . s. F. Hirsch Wolf, H . U . and K. Gietzen, The solubilization of high-

affinity Ca2^-ATPase of human erythrocyte mem­branes 1272*

Wolf, M . de, A. Lagrou, H . J. Hilderson and W. Die-rick, Sedimentable phospholipase A 2 activity in bovine thyroid tissue 1272*

Wolf, M . de s. H . J. Hilderson Wolfrum, D. I . , R. Rüchel, S. Mesecke und V. Neuhoff,

Mikroelektrophorese in kontinuierlichen Polyacryl-amid-Gradientengelen, I I I : Extraktion und Fraktio­nierung von Ribonucleinsäuren im Mikromaßstab 1415

Wolfrum, D.-I. s. R. Rüchel Wollenberg, P. s. G. Müllhofer Wollmer, A., D.Brandenburg, H.-P. Vogt and W.

Schermutzki, Reduction/reoxidation studies with cross-linked insulin derivatives 1471

Woloszczuk, W. and O. Hoffmann-Ostenhof, Studies on the biosynthesis of cyclitols, X X X I : Further investigations on the biosynthesis of laminitol (1D-4-C-methyl-w^o-inositol) in Porphyridium sp. 633

Wurster, B. and B. Hess, Glucose-6-phosphate 1-epi-merase from bakers' yeast: Purification, properties and possible biological function 255

Yantorno, C. s. E. Nowotny Verna, M. J. s. M . Roberfroid Ysebaert, M. s. W. Min Jou Yuki, A. and H . G. Wittmann, A new RNA of high

molecular weight in Escherichia coli 1562

Zapf, B. s. P. Schmialek Zepf, E. s. A. K. Walli Zerban, H. s. H . H . Paradies Ziegler, W. s. H . Wiegandt Zierenberg, O. s. W. Stoffel Zilliken, F. s. M . Giesing Zimmer, G. and G. Ohlenschläger, 2-Mercaptopropio-

nylglycine, a new SH-reagent for mitochondria .1273*

Zimmer, G. and H. Schirmer, Different influence of glucose and sorbose on erythrocyte membrane lipid transition 1273*

Zimmermann, G. s. E. Latzko Zobeley, S. s. H . Faulstich

Titel Nr. 3 109 001 342. © Copyright 1974 by Walter de Gruyter & Co., Berlin. Alle Rechte, insbesondere die der Übersetzung in fremde Sprachen, vorbehalten. Kein Teil dieser Zeitschrift darf ohne schriftliche Genehmi­gung des Verlages in irgendeiner Form — durch Photokopie, Mikrofilm oder irgendein anderes Verfahren — reproduziert oder in eine von Maschinen, insbesondere von Datenverarbeitungsmaschinen verwendbare Sprache übertragen oder übersetzt werden. — All rights reserved, including those of translations into foreign languages. No part of this journal may be reproduced in any form-by photoprint, microfilm or any other means - or transmitted or translated into a machine language without written permission from the publisher. Nach § 54, Abs. 2 U R G ist für die photomechanische, xerographische oder in sonstiger Weise bewirkte Anfertigung von Vervielfältigungen der in dieser Zeitschrift erschienenen Beiträge zum eigenen Gebrauch eine Vergütung zu bezahlen, wenn die Vervielfältigung gewerblichen Zwecken dient. Die Vergütung ist nach Maßgabe des zwischen dem Börsenverein des Deutschen Buchhandels e.V., Frankfurt/Main, und dem Bundesverband der Deutschen Industrie in Köln abgeschlossenen Gesamtvertrages vom 15. Juli 1970 zu entrichten. Die Weitergabe von Vervielfältigungen, gleichgültig zu welchem Zweck sie hergestellt werden, ist eine Urheberrechtsverletzung und wird strafrechtlich ver­folgt. Die hier genannten Vervielfältigungen haben den Vermerk über den Hersteller und die Bezahlung der Lizenzen zu tragen. Die Wieder­gabe von Gebrauchsnamen, Handelsnamen, Warenbezeichnungen und dergleichen in dieser Zeitschrift berechtigt nicht zu der Annahme, daß solche Namen ohne weiteres von jedermann benutzt werden dürfen. Vielmehr handelt es sich häufig um gesetzlich geschützte, einge­tragene Warenzeichen, auch wenn sie nicht eigens als solche gekennzeichnet sind. — The quotation of registered names, trade names, trade marks, etc. in this journal does not imply, even in the absence of a specific statement, that such names are exempt from laws and regulations protecting trade marks, etc. and therefore free for general use. Anzeigenverwaltung: Merkur-Werbung, Dr. K . Jeserich K G , 521 Troisdorf 22, Merkur-Haus, Hauptstraße 23-27 , Tel. (02241)42051. Für den Anzeigenteil verantwortlich: Ursula Kunz, Troisdorf. - Printed in Germany — Satz und Druck: R. Oldenbourg, München.

1234 Joint Meeting 1974 Bd. 355 (1974)

W. Neupert

Cooperation of Mitochondrial and Cytoplasmic Protein Synthesis in the Formation of the Mitochondrial Mem­brane

Mitochondrial and cytoplasmic ribosomes contribute to the biogenesis of mitochondrial membranes. The two types of ribosomes have been shown to be different with respect to electron microscopic structure, sedimentation properties, protein and RNA composition and immuno­logical properties^1 -31. Polypeptides synthesized on mitochondrial ribosomes are integrated into the inner mitochondrial membrane, thus contributing ca. 15% of the total inner membrane protein. The other proteins of the inner membrane and those of the outer mitochondrial membrane are made by cytoplasmic ribosomes^4]. On the level of individual membrane proteins, the two types of ribosomes cooperate in the formation of cyto­chrome c oxidase (EC 1.9.3.1) and of oligomycin-sensitive ATPase (EC 3.6.1.3)f5~8l. For cytochrome b a cooperation is also discussed^. The best studied ex­ample is cytochrome oxidase, for which it is shown that three polypeptide subunits of the complex enzyme are translated on mitochondrial ribosomes and four sub-units on cytoplasmic ribosomest6'10!. The application of selective inhibitors of ribosomal function, e.g. cycloheximide for cytoplasmic ribosomes and chloramphenicol for mitochondrial ribosomes, has turned out to be useful in studies on the origin of sub-units and on their assembly to the complex enzyme!1 1-1 2'. Experiments with isolated mitochondria to study the formation of cytochrome oxidase in a reconstituted system are in an initial stage (A. v. Rücker, S. Werner and W. Neupert, unpublished results). The regulation mechanisms which guarantee the co­ordinated synthesis of membrane components on the two types of ribosomes are for the most part unknown. Experiments with Neurospora have shown that in the presence of chloramphenicol cytoplasmic protein syn­thesis continues and gives rise to even higher cellular concentrations of several mitochondrial components (e.g. cytochrome c). On the other hand, in cells treated with cycloheximide, the rate of amino acid incorporation into mitochondrial membrane protein decreases in an

exponential way with a t\l<> of ca. 10 min. However, the biosynthetic activity of mitochondrial ribosomes re­mains at a high level for several hours, as measured by the amount of nascent peptide chains on the ribosomes and by the rate of chain elongation. This indicates that the mitochondrial membrane has a limited number of binding sites for newly formed polypeptides of mito­chondrial origin provided by polypeptides of cyto­plasmic origin. If the system is out of balance, poly­peptides which cannot be integrated into the membrane may be subject to immediate degradation. Specific degradation of newly made polypeptides can be de­monstrated in isolated mitochondria. A mechanism for the regulation of cytoplasmic-mito­chondrial cooperation is proposed, in which the nucleus controls the activity of mitochondrial protein synthesis via the synthesis (and possibly turnover) of the com­ponents of the mitochondrial transcription and trans­lation machinery. Specific degrading enzymes may be responsible for a fine control. The number of mitochondrially formed polypeptides which can be attributed to definite membrane compo­nents is 5 or 6. The size of the mitochondrial genome (at least in higher eucaryotes) points to a maximal number of 10— 15 polypeptides. However, the possibility of messenger RNA import into mitochondria is not excluded. The question remains to be answered why for a few mitochondrial membrane enzymes two systems of transcription and translation have to cooperate. In this context, the following observations are important: 1. Until now, mitochondrial translation products were only found in membrane components which are in­volved in oxidative phosphorylation. 2. Mitochondrial translation products have a strongly hydrophobic character. For example, a mitochondrially made poly­peptide with a molecular weight of ca. 8500 was isolated from the nuclear mutant cni-1 of Neurospora which has an extremely high proportion of nonpolar amino acids (polarity 0.24) (R. Michel et al., unpublished results). This polypeptide is insoluble in water but soluble in chloroform/methanol. These observations led to the hypothesis that ribosomes are necessary inside the mitochondrial membrane to synthesize polypeptides which, because of their hydrophobic character, cannot be transported from the cytosol to the inner mitochon­drial membrane and which are essential for oxidative phosphorylation!13^.

1 Borst, P. & Grivell, L . A. (1971) FEBS Lett. 13, 73 -88.

2 Kleinow, W., Neupert, W. & Miller, F. (1974) J. Cell Biol., in press. 3 Hallermayer, G. & Neupert, W. (1974) FEBS Lett. 41, 264-268. 4 Neupert, W. & Ludwig, G. D. (1971) Eur. J. Biochem. 19, 523-532. 5 Weiss, H . , Sebald, W. & Bücher, Th. (1971) Eur. J. Biochem. 22, 19-26.

Bd. 355 (1974) Joint Meeting 1974 1235

ö Mason, T. L . &. Schatz, G. (1973) / . Biol. Chem. 248, 1355-1360.

7 Tzagoloff, A., Rubin, M . S. & Sierra, M . F. (1973) Bioclüm. Biophys. Acta 301, 71 - 104. 8 Jackl, G. & Sebald, W. (1974) this J. 355, 1211-1212. 9 Weiss, H . & Ziganke, B. (1974) Eur. J. Biochem. 41, 63-71 . 1 0 Sebald, W., Machleidt, W. & Otto, J. (1973) Eur. J. Biochem. 38, 311-324.

1 1 Sebald, W., Weiss, H . & Jackl, G. (1972) Eur. J. Bio­chem. 30,413-417. 1 2 Werner, S. (1974) Eur. J. Biochem. 43, 39-48. 1 3 Michel, R. & Neupert, W. (1973) Eur. J. Biochem. 36, 53-67.

Address: Priv.-Doz. Dr. W. Neupert, Institut für Phy­siologische Chemie und Physikalische Biochemie der Universität, D-8 München 2, Goethestr. 33.