HerzzentrumUniversitŠtsspital Basel

Herzzentrum

HerzzentrumJahresbericht 2016

02

Mehr wissen. Alles geben.Mehr machen. Besser kšnnen.Zusammen arbeiten. Mehr erreichen.

Diese Axiome fokussieren unsere Arbeit im Herzzentrum des UniversitŠtsspitals auf das Wesentliche:

Gemeinsam mehr erreichen fŸr eine optimale, Ÿberregionale Patientenversorgung, fŸr eine fundierte

Aus- und Weiterbildung, fŸr die universitŠre Wissenschaft, fŸr ein nachhaltiges Gesundheitssystem.

Diesen GrundsŠtzen folgend haben wir den diesjŠhrigen Jahresbericht auf das Wesentliche reduziert:

Teams, Zahlen, Fakten, Lehre & Forschung.

DafŸr stehen wir und unser Herzteam.

Friedrich Eckstein Stefan Osswald

03

Vorwort

04

Inhalt

01 Dienstleistungen 06 - 11 Leistungsstatistik Kardiologie UniversitŠtsspital Leistungsstatistik Herzchirurgie UniversitŠtsspital Leistungsstatistik PartnerspitŠler Outcomestatistik 02 Kardiologie 12 - 23 Interventionelle Kardiologie Elektrophysiologie Echokardiographie Cardiac Imaging Herzinsuffizienz KardiovaskulŠre PrŠvention / GUCH KARAMBA (Kardiale Rehabilitation) Kurzzeitklinik / Pflege / MTT / MTRA Administration / Controlling Outcome Forschung Swiss-AF Cohort Study Grundlagenforschung 03 Herzchirurgie 24 - 27

04 Notfallzentrum 28 - 29

05 Medizinische Intensivstation 30

06 KardioanŠsthesie 31

07 Operative Intensivbehandlung (OIB) 32 - 33

08 Lehre 34 - 35

09 Finanzielles 36 - 39 ForschungsbeitrŠge Sponsoren / Gšnner 10 Publikationen Kardiologie / Herzchirurgie 40 - 51 Originalarbeiten Reviews & Editorials Letters to the editor Case reports Book chapters

11 Auszeichnungen 52 - 53

12 Kontakt 54

05

StationŠre Patienten

Kardiologische Ambulatorien

Schrittmacherkontrollen

ICD-Kontrollen

Rhythmussprechstunde

Kardiologische AbklŠrungen

Herzinsuffizienz-Sprechstunde

LVAD-Kontrollen

GUCH-Sprechstunde

Privatsprechstunden

Hypertonie Sprechstunde

Rauchstopp Sprechstunde

Konsile

Spezialuntersuchungen

Linksherzkatheter

Rechtsherzkatheter

Myokard-Biopsie

Elektrophysiologische Untersuchungen

Echokardiographien, transthorakal

Echokardiographien, transoesophageal

Stressechokardiographien

24 h Blutdruckmessungen

Somnotouch

Herz-MR

Herz-CT

Ergometrien (inkl. Nuklearmedizin)

Spiroergometrien

Myokardperfusionsszintigraphien

Herz-PET

2014

1'870

1'704

1'757

403

678

460

n.a.

123

846

730

497

2'002

2'354

179

25

53

8'854

891

123

846

n.a.

627

277

1'195

83

1'571

n.a.

2013

1'830

1'499

1'774

458

1'072

423

n.a.

128

768

547

286

1'690

2'292

160

34

n.a.

7'665

872

64

754

n.a.

395

572

1'770

96

1'729

n.a.

2016

2'169

1'691

1'649

452

1'049

547

45

130

1'304

1'001

758

1'602

2'473

155

27

71

10'810

1'051

220

1'224

296

738

356

2'074

84

1'466

55

2015

2'051

1'644

1'514

398

881

547

n.a.

122

1008

813

541

1'459

2'525

175

23

80

9'275

979

145

1004

137

715

232

1'248

72

1'618

n.a.

Leistungsstatistik Kardiologie UniversitŠtsspital

Dienstleistungen

01 Dienstleistungen

06

Elektrokardiographie

Ruhe-EKG 1

Langzeit-EKG Untersuchungen inkl. R-Tests

Therapie

Kardioversionen

Schrittmacherimplantationen

Schrittmacherwechsel / Schrittmacherrevision

Elektrodenentfernungen

ICD-Implantationen

ICD-Wechsel / ICD-Revision

CRT-ICD / CRT-PM

Ablationen

PTCA

Mehrast-PTCA

Sinus Coronarius Reduktion

Valvuloplastien

Verschluss eines ASD / PFO

Nicht operativer Aortenklappenersatz (TAVI)

MitraClip

Indirekte Mitralklappenannuloplastie

Renale Denervationen

Vorhofsohrverschluss

MVP

ParavalvulŠrer Leckverschluss

TASH

Rehabilitation (KARAMBA)

2014

12'127

631

165

273

61

19

87

52

53

581

1'193

364

n.a.

2

47

107

18

n.a.

n.a.

7

4

n.a.

2

363

2013

12'028

867

176

237

79

20

99

46

49

436

1'130

286

n.a.

3

39

99

11

n.a.

6

7

3

1

4

284

2016

15'082

1'783

228

304

73

29

88

54

53

710

1'278

387

6

1

33

131

15

4

1

9

0

2

0

331

2015

11'473

1'842

208

283

77

15

125

47

57

646

1'279

422

n.a.

1

27

103

13

n.a.

1

11

5

n.a.

1

389

Leistungsstatistik Kardiologie UniversitŠtsspital

07

Bruderholzspital

Ruhe-EKG

Langzeit-EKG (24-h)

R-Tests

Ergometrien

Echokardiographie, transthorakal

Echokardiographie, transoesophageal

Stressechokardiographie

Myokardperfusionsszintigraphie (in Zusammenar. m. Radiol.)

MRI (in Zusammenarbeit mit Radiologie)

BD-Messung (24-h)

Schrittmacherkontrollen inkl. ICD

Schrittmacherimplantationen inkl. -wechsel

Kardioversionen

StationŠre Konsilien

Service de Cardiologie Hopital du Jura

Ergometrien

Echokardiographien, transthorakal

Echokardiographien, transoesophageal

MRI

EKG

R-Test

Schrittmacherimplantationen

Schrittmacherwechsel

Schrittmacherkontrollen

ICD-Kontrollen

Holter

2014

10'936

553

34

329

1'917

93

23

127

71

82

828

72

42

867

174

673

13

79

825

9

24

14

340

29

n.a.

2013

2'708

582

47

364

1'773

81

27

131

65

98

783

81

50

692

108

652

15

68

805

10

29

10

317

15

n.a.

2016

10'385

547

54

454

1'942

72

22

123

70

58

726

62

50

782

125

378

8

29

272

5

4

11

171

9

139

2015

11'539

633

38

340

1'948

83

25

119

78

118

828

67

44

735

136

537

4

84

424

12

31

17

374

36

n.a.

Leistungsstatistik PartnerspitŠler

Dienstleistungen

01 Dienstleistungen

08

Leistungsstatistik Herzchirurgie UniversitŠtsspital

Prozeduren

Operationen mit Herz-Lungen-Maschine (HLM)

Operationen ohne Herz-Lungen-Maschine (HLM)

Sonstige Operationen (Schrittmacher, ICD, Perikard, etc)

Kombinationseingriffe (Herzoperationen mit HLM)

Bypasschirurgie

Aortokoronarer Bypass (AKB) isoliert mit HLM

Aortokoronarer Bypass (AKB) ohne HLM ("OPCAB")

Kombinationseingriffe (AKB+)

Aortenklappenchirurgie

Aortenklappenersatz biologisch

Aortenklappenersatz mechanisch

Aortenklappenrekonstruktion mit Eigenperikard (OP nach Ozaki)

Aortenklappen- und Wurzelersatz ("Composite")

Aortenklappenrekonstruktion

Transapikaler Aortenklappenersatz (ohne HLM, mit Kardiol.)

AortoventrikulŠrer Bypass (AVB)

Mitralklappenchirurgie

Mitralklappenersatz mit HLM

Mitralklappenrekonstruktion mit HLM

Rekonstruktionsrate (geplant vs. durchgefŸhrt)

Andere

Trikuspidal- und Pulmonalklappenchirurgie

Trikuspidalklappenrekonstruktion

Pulmonalklappenersatz

2014

1'157

631

112

210

210

417

234

50

132

273

167

39

n.a.

35

36

31

0

117

31

85

n.a.

n.a.

15

14

1

2013

1'267

667

95

239

244

449

250

36

163

290

170

48

n.a.

30

31

32

3

126

26

98

n.a.

2

20

20

0

2016

1'098

533

121

196

198

313

168

27

116

234

127

35

15

13

24

19

0

121

46 (43/3)

73 (33/40)

98%

2

12

11

1

2015

1'031

568

101

195

195

345

208

29

110

208

119

34

8

23

25

18

0

133

43 (40/3)

87 (43/44)

97%

3

16

16

0

09

Operationen an der thorakalen Aorta

Sonstige Eingriffe

Vorhofablation/Pulmonalvenenisolation

Vorhofseptumdefekt

Extrakorporale Zirkulation (EKZ)

Minimalisierte EKZ ("MECC")

Hypothermer Kreislaufstillstand

Kardiale UnterstŸtzungssysteme

Intraaortale Ballonpulsation (IABP)

Extrakorporale Membranoxygenation (ECMO)

LVAD (Destinationstherapie)

Eingriffsdringlichkeit

Elektiv

Notfall

Dringlich

Konsile Kardiologie

2014

104

53

21

32

631

232

79

53

31

22

n.a.

530

89

80

n.a.

2013

106

51

30

21

667

231

86

57

37

19

n.a.

573

94

70

n.a.

2016

82

48

10

38

533

146

74

49

28

21

3

567

154

129

285

2015

87

50

16

34

568

196

71

61

42

19

2

504

135

141

269

Leistungsstatistik Herzchirurgie UniversitŠtsspital

Dienstleistungen

01 Dienstleistungen

10

Outcome Statistik

Zentraler Fokus bei den von der Kardiologie des USB angebo-tenen Leistungen ist die medizinische QualitŠt. Gerade in Zei-ten einer rasanten Entwicklung vor allem in technischen Berei-chen der Medizin ist die exakte und lŸckenlose Aufarbeitung von Komplikationen und TodesfŠllen, welche im Spital auftreten (In-hospital Mortality) von enormer Wichtigkeit. Im Rahmen der QualitŠtskontrolle der Abteilung Kardiologie erfolgt eine syste-matische Erfassung aller Eingriffe, welche im Laufe eines Jahres durchgefŸhrt werden. Basierend auf interdisziplinŠren Bespre-chungen im Rahmen von sogenannten Morbidity & Mortality Konferenzen (M&M) wird dabei nicht nur die In-hospital Mortality

Anzahl

Untersuchungen

1278

1195

153

710

377

142

53

29

155

27

42

In-hospital Tod

N (%)

29 (2.3%)

28 (2.3%)

4 (2.6%)

2 (0.3%)

1 (0.3%)

0

0

0

2 (1.3%)

1 (3.7%)

0

Procedure-related Tod

N (%)

4 (0.3%)

2 (0.2%)

2 (1.3%)

0

0

0

0

0

0

0

0

Untersuchungstyp

PTCA / Stentimplantationen

Linksherzkatheter (ohne PTCA)

Interventionelle Klappeneingriffe *

Katheterablationen

Schrittmacher-Implantationen

Schrittmacher-Wechsel/-revision

ICD-Implantationen

ICD-Wechsel/-revision

CRT-ICD / CRT-PM

Elektrodenextraktion

Rechtsherzkatheter

Biopsie

ASD/PFO-Verschluss

* TAVI (n=131, davon 112 transfemoral), Valvuloplastien der Aortenklappe oder Mitralklappe (AVP: n=1, MVP: n=0), Mitraclip (n=15), indirekte Mitralklappenannuloplastie (n=4), Verschluss paravalvulŠres Leck (n=2)

sondern auch die Procedure-related Mortality ermittelt. Beides sind wichtige Messgršssen in der QualitŠtskontrolle, welche die Kardiologie des USB seit mehreren Jahren transparent rappor-tiert.

In der untenstehenden Tabelle sind alle TodesfŠlle aufgelistet, die nach einer kardiologischen Intervention aufgetreten sind. Hierzu ist anzumerken, dass dabei auch TodesfŠlle rapportiert werden, welche nicht kausal mit der Intervention zusammenhŠngen. Deshalb wird zusŠtzlich auch die procedure-related Mortality rapportiert.

11

Interventionelle Kardiologie

Team

�rztliches TeamProf. Christoph KaiserProf. Raban JegerProf. Peter BuserDr. G. FahrniDr. R. TwerenboldDr. Bastian Wein

Wissenschaftliches TeamDr. Nicole GilgenAndrea Harder-AllgšwerFranziska JordanMargarete Baumgartner

02 Kardiologie

12

Elektrophysiologie

Team

�rztliches TeamProf. Christian SticherlingProf. Stefan OsswaldPD Dr. Michael KŸhnePD Dr. Tobias ReichlinProf. Beat SchŠr

Technisches TeamDr. Sven KnechtFlorian Spies

Wissenschaftliches TeamSarah GiesebartFranziska Jordan

13

Echokardiographie

Team

Aerztliche Mitarbeiter EchokardiographiePD Dr. Beat KaufmannProf. Michael ZellwegerPD Dr. Otmar PfisterPD Dr. Daniel ToblerDr. Arnheid KesselDr. Wanda KloosDr. Jens LohrmannDr. Frank-Peter Stephan

Mitarbeiter Cardiovascular Molecular ImagingPD Dr. Beat KaufmannDr. Amanda Ochoa-EspinosaDr. Mukesh PunjabiDr. Lifen XuDavid Steinl

02 Kardiologie

14

Cardiac Imaging

Team

Prof. Michael ZellwegerProf. Peter BuserDr. Thilo BurkardDr. Philip Haaf

Kollaboration mit Radiologie und Nuklearmedizin

15

Herzinsuffizienz

Team

�rztliches TeamProf. Christian MŸllerPD Dr. Otmar PfisterProf. Peter RickenbacherProf. Peter BuserPD Dr. Gabriela Kuster PfisterDr. Zaid Sabti

Wissenschaftliches TeamSalome RŸmmlerFranziska Jordan

02 Kardiologie

16

KardiovaskulŠre PrŠvention / GUCH

Team KardiovaskulŠre PrŠvention/Hypertonie - Standort USB-MedPol

Dr. Thilo BurkardDr. Andrea MeienbergDr. Corinna KlŸberDr. Annina VischerDr. Karsten Murray, AA (1.1.-31.3.16)Dr. Firas Aldebssi, AA (1.6.-31.12.16)Dr. Ruth Debenath A� Medpol (1.1.-31.3.16)Dr. Janina Ršhm, A� Medpol (1.4.-30.9.16)Dr. Martina Frick, A� MedPol (1.10.-31.12.16)Uta EnglerNathalie Klaus

Team GUCH

PD Dr. Daniel ToblerProf. Birgit DonnerDr. Manuela Bernoulli A� (01.10.2016-31.12.2016)Dr. Sebastian Imhof AA (01.04.2016-30.06.2016)Dr. Nicolas Kozhuharov AA (01.07.2016-30.09.2016)Dr. Elena Lardi A� (01.10.2016-31.12.2016)Dr. Lukas Meier AA (1.1.2016-31.03.2016)Lukas NotzGaby Frey

17

KARAMBA (Kardiale Rehabilitation)

Team

PD Dr. Otmar PfisterDr. Thilo BurkardDr. Manuela Florence BernoulliDr. Cornelia GanzoniAndrea Iris BannwartAntonia Candela (ab 01/2017)Livia GrafTheresia Kohler Julia LŠderach-KaufmannRuth Ostertag-IrnigerSarah RiglingNicolas Rodriques (bis 12/2016)Monika Ršthlisberger-DubachStephanie RuchYolanda SanchezFabienne SchneiderMadeleine Wick

02 Kardiologie

18

Kurzzeitklinik / Pflege / MTT / MTRA

Team KUK (Station 8.2)

Susanne TimusCatherine MalgatProf. Christian MŸllerDr. Wanda KloosDr. Jens Lohrmann

Team Pflege / MTT

Rosemarie BŸhrerSšren LorenzNicole KunstBettina Andris (ab 01.06.16)Norman BaumgŠrtelBianca Behrendt (01.06.-31.07.16)Paul BlindAnnette BusConstance DeiningerNecla Demir (ab 01.08.16)Klaus Peter Gunsch Kathrin Hendrych (bis 29.02.16)Antje HenkeChristina HuldiClaudia KernbachHeidi Linder Claudia Lutz Daniele Minio Andrea MusslerMonika Schwager (bis 29.02.16) Mandy Schwieger (bis 30.11.16Brigitta Sorg Kristina Valaityte Brigitte WiedmerAlice Wingerdt

Team MTRA

Severine Dziergwa Nadine Ruettener Manuel Reidy Selina Botta Lea BurriStefan Devries FrŠnzi Giger Barbara ImfeldMatthias Merz Katja Obhues Christine Orsingher Salome Seppi Kathrin Waidele Gina Wietschorke Feride Yesilyayla

19

Administration / Controlling

Team

Arton JusajRocio AlvarezEla AriBilal BektasGaby FreyMelanie JostJolanda MŸllerSarah RiglingNicholas RodriquesAleksandra SchweizerChristina SchottGaby SchwobSanja TrifkovicUrsula Vogt

02 Kardiologie

20 21

Outcome Forschung

Team

Prof. Danielle Menosi GualandroDr. Ayman AlhussiniDr. Patrick BadertscherDr. Sanela BaracDr. Paul Jasper BoeddinghausDr. Ina-Maria Ferel-HarwrthDr. Ivana DinclovicDr. Daniela ErnstDr. Cornelia GanzoniDr. Karin GrimmDr. Beate HartmannDr. Nikola KozhuharovDr. Caroline KulangaraDr. Riham MahfouzDr. Ewa MilopolskaDr. Christian PuelacherDr. Zaid SabtiDr. Samyut ShrestaNathalie Rose, PhD

02 Kardiologie / Klinische Forschung

Mustafa AssadianSara BarataPatrick BergsmaDominik BreitenbŸcherSydney Corbi�reJanosch CupaJeanne du Fay de LavallazDayana Flores WidmerMichael FreeseNatascha HerrJonas HiltiUrsina HoneggerClaudia HuckRahel IsenrichIrina KlimmeckChristine KruseSabrina LauleNundsin Vanessa LhasamSarah LšffelStella MarbotPatrick MŠchlerKathrin Meissner

Deborah MŸllerJulian PfŠffliKristin PodkowikMarkus RiestererTherese RinderknechtNicolas SchŠrliDeborah SchneiderAline Alessandra SchšniMarie SchuberaCarmela SchumacherLukas SchumacherDaniela SeebergerClaudia StelzigIvo StrebelKathrin Luzia ThommenDevran TopyŸrekMichael TschukJanine VšgeleFabian Vogt Joan Elias WalterAndres Zimmerli

21

Swiss-AF Cohort Study

Team

Swiss-AF Cohort StudyProf. David ConenProf. Stefan OsswaldPD Dr. Michael KŸhneProf. Christian SticherlingDr. Stefanie AeschbacherDr. Steffen BlumDr. Philipp KrisaiDr. Christiane PudenzDr. Tobias SchšnDr. Anne SpringerLaura DšrigLucien EggimannPeter EgliAndreas FischerRahel KreuzmannThomas KoflerPascal MeyreChristoph MuffAndreas ReusserJavier RupertiGian Všllmin

22

02 Kardiologie / Klinische Forschung

23

Cardio Biology

Team

Prof. Marijke Brink, ForschungsleiterinChristian Morandi, MScLifen Xu, PhDSonia LebboukhPhilippe HeimJoseph Iharinjaka Randriamboavonjy, PhD (seit 9.16)

Myocardial Research

Team

PD Dr. Gabriela Kuster Pfister PD Dr. Otmar PfisterM. Sc. Vera LorenzDr. Lifen XuDr. Michika Sato MochizukiM. Sc. Giacomo Della VerdeM. Sc. Daria Monogiou Belik

Molecular Imaging

Team

PD Dr. Beat KaufmannDr. Mukesh PunjabiDr. Lifen XuDr. Amanda Ochoa-EspinosaDavid Steinl

02 Kardiologie / Grundlagenforschung

23

Klinik fŸr Herzchirurgie

Team

�rzteProf. Friedrich Eckstein PD Dr. Oliver Reuthebuch PD Dr. Martin Grapow PD Dr. Denis Berdajs (seit 06/16) Prof. Dr. Peter Matt (bis 05/16) Dr. Florian RŸter Dr. Ulrich Schurr

IMC ChirurgieDr. Pierre Branitzki Dr. Clemens Dovifat Dr. Karin Fuhrmann-Hilbrecht Mairi Ziaka Kerstin Buchholz (bis 06/16)

03 Herzchirurgie

Fachassistenten HerzchirurgieStefan Adamcik (seit 04/16)Dr. Prerana Banerjee (seit 06/16)Dr. Ludovic Melly (bis 02/16)Myroslava Mytsyk (seit 04/16)Dr. Jasmin Hasmik Shahinian Dr. Charlotte Wichmann (bis 06/16)

Rotationsassistenten ChirurgieVladislav BorisovMarc-Antoine BurchDr. Wolfgang KricklWitali Gorelow

Rotationsassistenten KardiologieDr. Marc HŠfligerSebastian KoppClaudia Joha

Rotationsassistenten Innere MedizinChristian AnsprengerDr. Jasper BšddinghausDr. Lara Hitz

24 25

Klinik fŸr Herzchirurgie

Team

KardiotechnikerThomas Dšbele (Leitung)Claudia EndresBejtush RrahmaniDr. Antoine Simons (seit 08/16)Urs Zenklusen

ForschungsgruppenteamPD Dr. Anna Marsano Giulia Cerino, PhD Giuseppe Isu Giuseppe Pisani Emanuele Gaudiello, MSc Thomas Grussenmeyer, PhD Dietlinde John-Steinberg Myroslava Mytsyk

Chirurgische Intermediate Care Station (IMC)Vitomir Jankovic Manuela Buchacher

Chirurgische Station 4.1Marcel Hentz Stephanie Beyeler Simon Scheifele Karin Steiger

Chirurgische Station 7.1Sibylle Waldmann Silvia Violante

03 Herzchirurgie

26

SekretariatJolanda Giess Miriam Boughalmi Laura Voegeli Petra Vocat Bettina Kohler

27

Notfallzentrum

Team

�rzte KaderProf. Dr. Roland BingisserPD Dr. Christian NickelDr. Cristian BecaDr. Luc BlattmannDr. Nicolas BlessDr. Gerhard JŠckhDr. Gilbert KrŠhenbŸhlDr. Kriemhild LippayDr. Gregory MansellaDr. Vera PedersenDr. Manuel PuntschuhDr. Elisabeth RatzenbšckDr. Christiane RosinDr. Jochen RŸdigerDr. Eckehart SchšllDr. Sonia Shamdasani

Pflege KaderKathrin MatheisThorsten AlthunThomas DreherFranziska ImmbodenKai LŸbenUrsula Neff

04 Notfallzentrum

28

AdministrationMonika StadlerArtur Stickel

29

Medizinische Intensivstation

Team

�rzteProf. Stephan Marsch Prof. Patrick Hunziker Dr. Andres Christ Dr. Kai Tisljar Dr. Gianmarco Balestra Dr. Eva Hammel Dr. Jorge Kasper Dr. Heidi Lederer Dr. Magnus Stalder Dr. Karin Wildi

PflegeAngelika Lehmann Monika Strohmeier Sabine Hiller Lukas Weibel Christian Emsden Marie-Noelle von Allmen

SekretariatDeborah Minnig

05 Medizinische Intensivstation

30

KardioanŠsthesie

Team

�rztePD Dr. Jens Fassl PD Dr. Daniel Bolliger Dr. Joachim Erb Dr. Markus Maurer Dr. David Heppel Dr. Stefan Gisin Dr. Andreas Lampart Dr. Jonas Quitt Dr. Dominik Kallias

PflegeteamIsabelle Gisler Elisabeth Goustiaux Michael Gregor

06 KardioanŠsthesie

31

Operative Intensivbehandlung (OIB)

Team

�rzteProf. Dr. Hans ParggerPD Dr. Martin SiegemundDr. Nadine CueniDr. Jan BittnerPD Dr. Andrea Kopp LugliDr. Andreas LŸdinDr. Benjamin MŸllerDr. Sarah SalvatoDr. Patric SchlegelDr. Daniel TuchschererDr. Marianne Zumbrunn

PflegeMichael WehrliClaudia SpychigerUrsula Barandun SchŠferConrad Wesch

SekretariatJanine Angliker

07 Operative Intensivbehandlung (OIB)

32 33

Lehre

08 Lehre

Weiter- und Fortbildungs-Veranstaltungen

Externe Weiter- und Fortbildung¥ Rhythmusvisite Kantonsspital Aarau 1 x Monat¥ Regionale Fortbildungskurse (Rheinfelden / Bad Bubendorf)

Interne Weiter- und Fortbildung¥ CCU-Rapport, tŠglich 08.00 Uhr¥ Kardiologie, Montag 08.15 Uhr¥ Herzchirurgie, Montag 07.30-08.00 Uhr¥ Departements Konferenz Chirurgie, Montag 08.10-9.00 Uhr¥ Echokardiographie Fortbildung, Montag 12.30-13.30 Uhr¥ Kardiochirurgisches und -medizinisches Meeting, Montag 17.00 Uhr¥ Curriculum AA, Dienstag 7.45 Uhr¥ Seminar KardiovaskulŠre Grundlagenforschung, 1x Monat, alternierend Mo 09.00-10.00 Uhr, bzw. Di 10:30-11:30 Uhr¥ Herzinsuffizienz Lunch, jeweils jeden dritten Dienstag im Monat 12.30-13.30 Uhr¥ Research-Lunch, alle 14 Tage, Dienstag 12.30-13.30 Uhr¥ Kardiochirurgisches und -medizinisches Meeting, Mittwoch, 17.00 Uhr¥ Kardio-Lunch, Donnerstag 12.30-13.30 Uhr¥ Journal Club, Freitag 08.15-9.00 Uhr¥ PCI-Lunch, 1 x Monat, Mittwoch/Freitag 12.20-13.30 Uhr ¥ Rhythm and Pizza, 1 x Monat, Freitag 12.30-13.30 Uhr¥ Mortality & Morbidity Conference, 1 x Monat, Freitag 12.30-13.30 Uhr¥ Problemorientierte Fall Tutorate (2. Jahreskurs Medizinische FakultŠt Basel)¥ Arzt-Patienten-Unterricht (4. und 6. Jahreskurs Medizinische FakultŠt Basel)

Selbstorganisierte Kongresse / Symposien der Kardiologie Basel

¥ medArt 2016, Juni 2016, Basel¥ InteruniversitŠres GUCH-Kolloquium, September 2016

Kongresse / Symposien mit Basler Hauptorganisation

¥ 18. Winter-Meeting, Swiss Working Group for Heart Failure, 21. - 23. Januar 2016, Grindelwald¥ Arrhythmia Summit 21.4.2016, Basel¥ Journ�e de Biologie Paris, 22. - 24.06.2016¥ GREAT Meeting Rom, September 2016¥ "New Swiss Horizon" Electrophysiology-meeting Lenzerheide, 23./24.09.2016 ¥ DreilŠndertreffen Herzinsuffizienz Halle an der Saale, 19. - 21. Oktober 2016¥ EKG Kurs fŸr Assistenten, 27./28.10.2016, Luzern¥ EHRA Education Program for Physisicans- Implantable Cardioverter Defibrillator Module, Berlin, 17.-18.11.2016

34

Einsitz in Standesorganisationen

¥ Prof. C. Sticherling Mitglied des Scientific Writing Committees der European Heart Rhythm Association (EHRA) Past-PrŠsident der AG Herzschrittmacher und Elektrophysiologie der SGK Mitglied der Tarifkommission der SGK¥ Prof. M. Brink, Treasurer, PD Dr. med. Beat Kaufmann, Mitglied SGK, Working Group of Cardiovascular Biology¥ Prof. F. Eckstein VizeprŠsident im Vorstand der Schweizerischen Gesellschaft fŸr Herz- und Thorakale GefŠsschirurgie¥ PD Dr. B. Kaufmann SGK, Working Group Echocardiogaphy and Cardiac Imaging, VizeprŠsident SGK Working Group Cardiovascular Biology, Board Member Mitglied Tarifkommission der SGK¥ Prof. C. Kaiser Past-PrŠsident der Arbeitsgruppe Interventionelle Kardiologie der SGK¥ PD Dr. M. KŸhne Ambassador for young electrophysiologists der EHRA (European Heart Rhythm Association)¥ PD Dr. G. Kuster Pfister Mitglied Fachgruppe Frau & Herz der Schweizerischen Herzstiftung¥ Prof. Ch. MŸller Leiter, Dissertationsauszeichnungskommission der Medizinischen FakultŠt Basel European Society of Cardiology, Acute Cardiovascular Care Association, Board Member European Society of Cardiology, Heart Failure Association, Board Member European Society of Cardiology, Biomarker Study Group, Member European Society of Cardiology, Acute Cardiovascular Care Association, Acute Heart FAilure Study Group, chair European Society of Cardiology, Heart Failure Association, Committee on Diagnosis, chair European Society of Cardiology, Heart Failure Association, Committee on Acute Heart Failure, member GREAT Network, Vice president¥ PD Dr. O. Pfister Past President Arbeitsgruppe Herzinsuffizienz der Schweizerischen Gesellschaft fŸr Kardiologie¥ PD Dr. O. Reuthebuch RechnungsprŸfer der Schweizerischen Gesellschaft fŸr Herzchirurgie¥ PD Dr. D. Tobler SGK, Vorstandsmitglied der Arbeitsgruppe fŸr Erwachsene und Jugendliche mit angeborenen Herzfehlern (WATCH)¥ Prof. M. Zellweger PrŠsident der SGK

Ausbildung

¥ Prof. Marijke Brink: Themenblockleiterin: Themenblock Herz Kreislauf, 2. Bachelor Studienjahr Themenblock Co-leiterin, 1. Master Studienjahr Physiologie-Professorin (Vorlesungen, Praktika, Tutoriate)¥ PD Dr. Grapow: Tutoriat 1. JK, Betreuung von 3 Master Studenten, Betreuung von 1 Doktorandin¥ PD Dr. Reuthebuch: Betreuung von 2 Master Studenten¥ PD Dr. Reichlin: OSCE Staatsexamen¥ Prof. Christian MŸller: Betreuung von 10 Masterstudenten / Tutoriat 4. JK / Betreuung von 14 Doktoranden¥ Prof. SchŠr: Themenblockorganisator¥ Prof. Sticherling, Prof. Osswald, Prof. SchŠr, PD Dr. KŸhne: Vorlesungen ¥ Prof. Sticherling, Prof. Osswald, Prof. SchŠr, PD Dr. KŸhne, PD Dr. Reichlin: EKG Kurs

35

Finanzielles

09 Finanzielles

ForschungsbeitrŠge

Schweizer Nationalfonds

¥ SNF Projektfšrderung 310030_149718: Kaufmann B. Non-invasive ultrasound molecular imaging of myocarditis and autoimmune myocardial inflammation Beginn: 01.04.2014 / 3 Jahre¥ SNF Professur Nr: PP00P3_133681: Conen D.: Risk factors and outcomes associated with the progression of human atrial fibrillation: Role of Inflammation, Oxidative Stress and Fibrosis in the Initiation and Progression of Human Atrial Fibrillation: 2011-2016 Beginn: 01.07.2011 / 5 Jahre¥ SNF Projektfšrderung 310030-169996: Brink M "Gender-specific mechanisms of cardiac dysfunction in obesity" Beginn 01.10.2016 / 3 Jahre¥ SNF Projektfšrderung 33IC30_166855/1: Tobler D. Effect of phosphodiesterase-5 inhibition with tadalafil on systemic right ventricular function � a multi-center, double-blind- randomized, placebo-controlled clinical trial Beginn: 01.01.2016 / 5 Jahre¥ SNF Projektfšrderung 156953: Kuster G./Pfister O. Regulators of cardiac progenitor cells: Focus on cancer drug targets Beginn / Dauer: 1.1.2016 / 3 Jahre¥ SWISS-AF (Longitudinal Studies): 33CS30_148474: Conen D., Osswald S. Swiss Atrial Fibrillation Cohort Study Beginn: 01.03.2014 / 4 Jahre¥ SNF Projektfšrderung Nr. 32003B_159495/1: MŸller C. APACE Validation Beginn: 01.01.2016 / 3 Jahre

EU-Grants

¥ 2013 European Union FP7-Health_2013_Innovation 1 (Project 602299): Sticherling C. EU-CERT-ICD Comparative effectiveness research to assess the use of primary prophylactic implantable cardioverter defibrillators in Europe Beginn: 1.10.2013 / 4 Jahre

¥ Eurostars: "E!9799 ALVALE: Tobias Reichlin Anatomical Localization of the origin of Ventricular Arrhythmias from the 12-Lead ECG" Beginn: 1.1.16 / 1,5 Jahre

36

Schweizerische Herzstiftung

¥ Rubini-G. M: Addressing gender-specific inequalties in the early diagnosis and management of acute cardiovascular diseases Beginn: 01.11.2016 / 1 Jahr¥ MŸller C.: Advantageous predictors of acute coronary syndromes evaluation (APACE, Phase III) Beginn: 01.11.2016 / 1 Jahr

KTI

¥ Projektfšrderung: MŸller C. Nicht-invasive Diagnose der koronaren Herzerkrankung: Innovative Anwendung von Biomarkern und EKG-Signalen Beginn: 01.07.2014 / 2 Jahre

Stiftung fŸr kardiovaskulŠre Forschung Basel

¥ Brink M., Conen D., Jeger R., Kaiser C., Kaufmann B., Kuster Pfister G., MŸller C., Pfister O., Sticherling C., Zellweger M.

ForschungsbeitrŠge UniversitŠt Basel

¥ Kuster G.: Molecular mechanisms of matrix-instructed cardiac progenitor cell fate Beginn / Dauer: 1.1.2016 / 1 Jahr

37

Finanzielles

09 Finanzielles

Andere Quellen / Stiftungen

¥ Swiss Life AG JubilŠumsstiftung G. Kuster: Impact of Flt3-disruption on cardiac progenitor cell homeostasis and function: Implications for cancer therapy-related cardiotoxicity Beginn / Dauer: 1.1.2015 / 2 Jahre¥ Goldschmidt-Jacobsen-Stiftung T. Reichlin: Refinement and Integration of Advanced ECG Technologies in Clinical Cardiology Beginn / Dauer: 1.4.2015 / 3 Jahre

Andere Quellen / Industrie

¥ Abbott: Advantageous predictors of acute coronary syndromes evaluation (APACE), (MŸller C.) BASEL VIII (MŸller C)¥ BASEL-PMI (MŸller C)¥ Beckman Coulter: APACE (MŸller C)¥ Biomerieux: Advantageous predictors of acute coronary syndromes evaluation (APACE), (MŸller C.)¥ BRAHMS: Advantageous predictors of acute coronary syndromes evaluation (APACE), (MŸller C.) BASEL IX - Basel Syncope Evaluation Study (MŸller C.) BASEL V - Acute dyspnea (MŸller C.)¥ B. Braun Melsungen AG: BASKET-SMALL 2-Studie (Jeger R.)¥ Roche: Advantageous predictors of acute coronary syndromes evaluation (APACE), (MŸller C.) BASEL V - Acute dyspnea (MŸller C.) GALACTIC (MŸller C.)¥ Siemens: Advantageous predictors of acute coronary syndromes evaluation (APACE), (MŸller C.)¥ Singulex: Advantageous predictors of acute coronary syndromes evaluation (APACE), (MŸller C.) BASEL VII - Acute Abdominal Pain (MŸller C.) Biochemical and electrocardiographic signatures to detect exercise-induced myocardial ischemia (MŸller C.) BASEL V, BASEL VIII, BASEL IX (MŸller C.)

38

Sponsoren und Gšnner

¥ Abbott AG¥ Actelion Schweiz¥ A. Menarini AG¥ AstraZeneca AG¥ Bayer (Schweiz) AG¥ Biosense Webster¥ Biotronik Schweiz AG¥ Boehringer Ingelheim ¥ Boston Scientific¥ B.R.A.H.M.S. GmbH¥ B. Braun Melsungen AG¥ BŸhlmann Laborator AG¥ concile¥ Cordis Johnson & Johnson¥ Daiichi Sankyo (Schweiz) AG¥ 8sens biognostics GmbH¥ Edwards Life Science AG¥ Eli Lilly (Suisse) SA¥ Fšrderverein Kardiologie Basel¥ GlaxoSmithKline AG¥ GrŸnenthal Pharma AG¥ Guidant Europe SA¥ IBSA¥ J.C. General Serv. CVBA¥ Johnson & Johnson

¥ Medtronic (Schweiz) AG¥ mepha¥ Merck Sharp & Dohme¥ Mundipharma Medical Company¥ Novartis AG¥ novo nordisk¥ Nycomed Pharma AG¥ Pfizer AG¥ Robapharm AG¥ Roche¥ Sandoz Pharmaceuticals AG¥ Sanofi Aventis SA¥ Schwabe Pharma AG¥ Sigma-Tau Pharma AG¥ Stentys ¥ Stiftung fŸr kardiovaskulŠre Forschung Basel¥ St. Jude Medical (Schweiz) AG¥ Sorin ¥ Swiss Life AG¥ Takeda Pharma AG¥ Terumo ¥ The Medicines Company¥ Vifor Pharma¥ Viollier AG

39

Publikationen

Originalarbeiten

1. Aeschbacher S, Bossard M, Ruperti Repilado FJ, Good N, Schoen T, Zimny M, Probst-Hensch NM, Schmidt-TrucksŠss A, Risch M, Risch L, Conen D. Healthy lifestyle and heart rate variability in young adults. Eur J Prev Cardiol. 2016;23(10):1037-44. Impact Factor 3.361

2. Aeschbacher S, Bossard M, Schoen T, Schmidlin D, Muff C, Maseli A, Leuppi JD, Miedinger D, Probst-Hensch NM, Schmidt-TrucksŠss A, Risch M, Risch L, Conen D. Heart rate variability and sleep-related brea-thing disorders in the general population. Am J Cardiol 2016;118(6):912-7. Impact Factor 3.154

3. Aeschbacher S, Schoen T, Dšrig L, Kreuzmann R, Neuhauser C, Schmidt-TrucksŠss A, Probst-Hensch NM, Risch M, Risch L, Conen D. Heart rate, heart rate variability and inflammatory biomarkers among young and healthy adults. Ann Med 2016: Epub ahead of print. Impact Factor 3.763

4. Aeschbacher S., Metin F., Bossard M., Schoen T., von Rotz M., Mettler H., AbŠcherli R., Risch M., Risch L., Conen D. Relationships of electro-cardiographic parameters with ambulatory hypertension in young and healthy adults. Int J Cardiol 2016; 202:300-304. Impact Factor 4.638

5. Aimo A., Vergaro G., Ripoli A., Bayes Genis A., Pascual-Figal D.A., De Boer R., Lassus J., Mebazaa A., Gayat E., Breidthardt T., Sabti Z., Mueller C., Tang W., Grodin J.L., Zhang Y., Bettencourt P., Maisel A.S., Januzzi J.L., Emdin L. Prognostic value of soluble suppression of tumorigenici-ty-2 (sST2) in acute heart failure: a meta-analysis. JACC Heart Failure 2016 in press. Impact Factor 7

6. Asgar A, Chandrasekhar J, Mikhail G, Webb J, Lef�vre T, Tamburino C, Hildick-Smith D, Hambrecht R, Van Belle E, Widder J, Dumonteil N, Hink U, Jeger R, Linke A, Deliargyris E, Gao P, Mehran R, Hengstenberg C, Anthopoulos P, Dangas G; BRAVO-3 Investigators. Sex-based differen-ces in outcomes with bivalirudin or unfractionated heparin for transca-theter aortic valve replacement: Results from the BRAVO-3 randomized trial. Catheter Cardiovasc Interv. 2016 May 6. doi: 10.1002/ccd.26607. [Epub ahead of print] Impact Factor 2.181

7. Baber U, Giustino G, Sartori S, Aquino M, Stefanini GG, Steg PG, Windecker S, Leon MB, Wijns W, Serruys PW, Valgimigli M, Stone GW, Dangas GD, Morice MC, Camenzind E, Weisz G, Smits PC, Kandzari D, Von Birgelen C, Mastoris I, Galatius S, Jeger RV, Kimura T, Mikhail GW, Itchhaporia D, Mehta L, Ortega R, Kim HS, Kastrati A, Chieffo A, Mehran R.Effect of Chronic Kidney Disease in Women Undergoing Percutaneous Coronary Intervention With Drug-Eluting Stents: A Patient-Level Pooled Analysis of Randomized Controlled Trials. JACC Cardiovasc Interv. 2016 Jan 11;9(1):28-38. doi: 10.1016/j.jcin.2015.09.023. Impact Factor 7.630

10 Publikationen

8. Bel M, Panteghini M, Plebani M, Verschuren F, Jernberg T, French JK, Christenson RH, Body R, McCord J, Dilba P, Katus HA, Mueller C; for the TRAPID-AMI Investigators. Age- and Gender-specific Compared to Gene-ral 99th Percentile Cut-offs for Diagnosis of Myocardial Infarction and Pro-gnostic Implications -Sub-analysis from the TRAPID-AMI (High-sensitivity cardiac Troponin T assay for RAPID rule-out of Acute Myocardial Infarc-tion) Study. Int J Cardiol. 2016; Apr 15;209:26-33. Impact Factor 4.638

9. Beri N., Marston N.A., Daniels L.B., Nowak R.M., Schreiber D., Muel-ler C., Jaffe A., Diercks D.B., Wettersten N., DeFilippi C., Peacock W.F., Limkakeng A.T., Anand I., McCord J., Hollander J.E., Wu A.H., Apple F.S., Nagurney J.T., Berardi C., Cannon C.M., Clopton P., Neath S.X., Christenson R.H., Hogan C., Vilke G., Maisel A. Necessity of hospitaliza-tion and stress testing in low risk chest pain patients. Am J Emerg Med. 2016 Oct 29. Epub ahead of print. Impact Factor 2

10. Boccardo S, Gaudiello E, Melly L, Cerino G, Ricci D, Martin I, Eckstein F, Banfi A, Marsano A. Engineered mesenchymal cell-based patches as controlled VEGF delivery systems to induce extrinsic angiogenesis. Acta Biomater. 2016 Sep 15;42:127-35. doi: 10.1016/j.actbio.2016.07.041. Epub 2016 Jul 25. Impact Factor 6.008

11. Body R, Mueller C, Giannitsis E, Christ M, Ordonez-Llanos J, de Fi-lippi CR, Nowak R, Panteghini M, Jernberg T, Plebani M, Verschuren F, French JK, Christenson R, Weiser S, Bendig G, Dilba P, Lindahl B; for the TRAPID-AMI Investigators. The use of very low levels of high sensitivity troponin T to rule out acute myocardial infarction using a single blood test. Acad Emerg Med J. 2016; Sep;23(9):1004-13. Impact Factor 3.0

12. Boeddinghaus J, Reichlin T, Cullen L, Greenslade JH, Parsonage WA, Hammett C, Pickering JW, Hawkins T, Aldous S, Twerenbold R, Wildi K, Nestelberger T, Grimm K, Rubini Gimenez M, Puelacher C, Kern V, Rentsch K, Than M, Mueller C. Two-Hour Algorithm for Triage Towards Rule-Out and Rule-In of Acute Myocardial Infarction by Use of High-Sensitivity Cardiac Troponin I. Clin Chem. 2016; Mar;62(3):494-504. Im-pact Factor 7.911

13. Bolliger D, Filipovic M, Matt P, Tanaka KA, Gregor M, Zenklusen U, Seeberger MD, Lurati Buse G. Reduced aspirin responsiveness as assessed by impedance aggregometry is not associated with adver-se outcome after cardiac surgery in a small low-risk cohort. Platelets. 2016;27(3):254-61. Impact Factor 3.213

14. Bossard M, Kreuzmann R, Hochgruber T, Krisai P, Zimmermann AJ, Aeschbacher S, Pumpol K, Kessel-Schaefer A, Stephan FP, Handschin N, Sticherling C, Osswald S, Kaufmann BA, Par� G, KŸhne M, Conen D. De-terminants of Left Atrial Volume in Patients with Atrial Fibrillation. PLoS One. 2016 Oct 4;11(10):e0164145. doi: 10.1371/ journal. pone. 0164145. Impact Factor 4.411

40

15. Bossard M, Th�riault S, Aeschbacher S, Schoen T, Kunz S, von Rotz M, Estis J, Todd J, Risch M, Mueller C, Risch L, Par� G, Conen D. Factors independently associated with cardiac troponin I levels in young and healthy adults from the general population. Clin Res Cardiol 2016;Epub ahead of print. Impact Factor 4.324

16. Breidthardt T., Moreno Weidmann Z., Twerenbold R., Gantenbein C., Stallone F., Rentsch K., Rubini Gimenez M., Kozhuharov N., Sabti Z., BreitenbŸcher D., Wildi K., Puelacher C., Honegger U., Wagener M., Schumacher C., Hillinger P., Osswald S., Mueller C. Impact of Haemo-concentration during Acute Heart Failure Therapy on Mortality and its Relationship with Worsening Renal Function. Eur J Heart Fail 2016; Oct 19. doi: 10.1002/ejhf.667. [Epub ahead of print. Impact Factor 5.135

17. Brenner R, Ammann P, Yoon SI, Christen S, Hellermann J, Girod G, Knaus U, Duru F, Krasniqi N, Ramsay D, Sticherling C, Lippuner, KŸhne M. Reduction of falls and fractures after permanent pacemaker implan-tation in elderly patients with sinus node dysfunction. Europace 2016 (in press). Impact Factor 4.021

18. Brown J.R., Pearlman D.M, Marshall E., MacKenzie T.A., Recio-May-oral A., Gomes V.O.,Kim B., Jensen L.O., Mueller C., Maioli M., Solomon R.J. Individual Patient Data Meta-Analysis of Sodium Bicarbonate versus Sodium Chloride for All-Cause Mortality After Coronary Angiography. Am J Cardiol 2016; Nov 15;118(10):1473-1479. Impact Factor 3.154

19. Celikyurt U, Knecht S, Kuehne M, Reichlin T, Muehl A, Osswald S, Sti-cherling C. Incidence of new-onset atrial fibrillation after cavotricuspid isth-mus ablation for atrial flutter. Europace 2016 (in press). Impact Factor 4.021

20. Cerino G, Gaudiello E, Grussenmeyer T, Melly L, Massai D, Banfi A, Martin I, Eckstein F, Grapow M, Marsano A. Three dimensional multi-cellular muscle-like tissue engineering in perfusion-based bioreactors. Biotechnol Bioeng. 2016 Jan;113(1):226-36. Impact Factor 4.243

21. Chapman A., Anand A., Boeddinghaus J., Ferry A., Sandeman D., Adamson P., Andrews J., Tan S., Cheng S., D‘Souza M., Orme K., Stra-chan F., Nestelberger T., Twerenbold R., Badertscher P., Reichlin T., Gray A., Shah A., Mueller C., Newby D., Mills N. Comparison of the efficacy and safety of early rule out pathways for acute myocardial infarction. Circulation 2016; in press. Impact Factor 17.202

22. Christ Michael, Stefan Stšrk, Marcus Dšrr, Hans J. Heppner, Chris-tian MŸller, Rolf Wachter, and Uwe Riemer for the Trend HF Germany Project. Heart failure epidemiology 2000–2013: insights from the Ger-man Federal Health Monitoring System Eur J Heart Fail 2016; in press. Impact Factor 5.135

23. Conen D, Arendacká B, Ršver C, Bergau L, Munoz P, Wijers S, Sti-cherling C, Zabel M, Friede T. Gender differences in appropriate shocks and mortality among patients with primary prophylactic implantable cardioverter-defibrillators: Systematic review and meta-analysis. PLoS One 2016; 11(9): e0162756. Impact Factor 4.411

24. Conen D, Wong JA, Sandhu RK, Cook NR, Lee IM, Buring JE, Albert CM. Risk of malignant cancer among women with new-onset atrial fib-rillation. JAMA Cardiol 2016;1:389-396.

25. De Maria GL, Fahrni G, Alkhalil M, Cuculi F, Dawkins S, Wolfrum M, Choudhury RP, Forfar JC, Prendergast BD, Yetgin T, van Geuns RJ, Tebaldi M, Channon KM, Kharbanda RK, Rothwell PM, Valgimigli M, Banning AP. A tool for predicting the outcome of reperfusion in ST-elevation myocardial infarction using age, thrombotic burden and index of microcirculatory resistance (ATI score). EuroIntervention. 2016 Nov 20;12(10):1223-1230. Impact Factor 3.863

26. De Maria GL, Patel N, Wolfrum M, Fahrni G, Kassimis G, Porto I, Dawkins S, Choudhury RP, Forfar JC, Prendergast BD, Channon KM, Kharbanda RK, Garcia-Garcia HM, Banning AP. The influence of coronary plaque morphology assessed by optical coherence tomography on final microvascular function after stenting in patients with ST-elevation myo-cardial infarction. Coron Artery Dis. 2016 Dec 6. [Epub ahead of print] Impact Factor 1.553

27. Dobson L.E., Musa T.A., Uddin A., Fairbairn T.A., Swoboda P.P., Er-hayiem B., Foley J., Garg P., Haaf P., Fent G.J., Malkin C.J., Blackman D.J., Plein S., Greenwood J.P. Acute Reverse Remodelling After Transca-theter Aortic Valve Implantation: A Link Between Myocardial Fibrosis and Left Ventricular Mass Regression. Can J Cardiol. 2016 Dec;32(12):1411-1418. doi: 10.1016/j.cjca.2016.04.009. PMID:27523272. Impact Factor 3.112

28. Eser P, Herzig D, Vogt M, StŠmpfli R, Trovato M, Olstad DS, Trachsel L, Deluigi C, Wustmann K, Greutmann M, Tobler D, Stambach D, Schmid JP, Schwerzmann M, Wilhelm M. Vagal reactivation after exercise and cardiac autonomic nervous activity in adult Fontan patients without pace-makers Int J Cardiol. 2016 Jun 28;220:527-533. Impact Factor 4.638

29. Fahrni G, Wolfrum M, De Maria GL, Banning AP, Benedetto U, Khar-banda RK. Prolonged High-Dose Bivalirudin Infusion Reduces Major Blee-ding Without Increasing Stent Thrombosis in Patients Undergoing Prima-ry Percutaneous Coronary Intervention: Novel Insights From an Updated Meta-Analysis. J Am Heart Assoc. 2016 Jul 22;5(7). Impact Factor 4.306

41

Publikationen

10 Publikationen

36. Giustino G, Baber U, Aquino M, Sartori S, Stone GW, Leon MB, Ge-nereux P, Dangas GD, Chandrasekhar J, Kimura T, Salianski O, Stefanini GG, Steg PG, Windecker S, Wijns W, Serruys PW, Valgimigli M, Morice MC, Camenzind E, Weisz G, Smits PC, Kandzari DE, Galatius S, Von Birgelen C, Saporito R, Jeger RV, Mikhail GW, Itchhaporia D, Mehta L, Ortega R, Kim HS, Kastrati A, Chieffo A, Mehran R. Safety and Efficacy of New-Generation Drug-Eluting Stents in Women Undergoing Complex Percutaneous Coronary Artery Revascularization: From the WIN-DES Collaborative Patient-Level Pooled Analysis. JACC Cardiovasc Interv. 2016 Apr 11;9:674-84 Impact Factor 7.630

37. Giustino G, Mastoris I, Baber U, Sartori S, Stone GW, Leon MB, Ser-ruys PW, Kastrati A, Windecker S, Valgimigli M, Dangas GD, Von Bir-gelen C, Smits PC, Kandzari D, Galatius S, Wijns W, Steg PG, Stefanini GG, Aquino M, Morice MC, Camenzind E, Weisz G, Jeger RV, Kimura T, Mikhail GW, Itchhaporia D, Mehta L, Ortega R, Kim HS, Chieffo A, Mehran R Correlates and Impact of Coronary Artery Calcifications in Wo-men Undergoing Percutaneous Coronary Intervention With Drug-Eluting Stents: From the Women in Innovation and Drug-Eluting Stents (WIN-DES) Collaboration. JACC Cardiovasc Interv. 2016 Sep 26;9(18):1890-901 Impact Factor 7.630

38. Haude M, Ince H, Abizaid A, Toelg R, Lemos PA, von Birgelen C, Christiansen EH, Wijns W, Neumann FJ, Kaiser C, Eeckhout E, Lim ST, Escaned J, Garcia-Garcia HM, Waksman R. Safety and performance of the second-generation drug-eluting absorbable metal scaff old in pati-ents with de-novo coronary artery lesions (BIOSOLVE-II): 6 monthresults of a prospective, multicentre, non-randomised, first-in-man trial. Lancet. 2016;31-9. Impact Factor 44.002

39. Haude M, Ince H, Abizaid A, Toelg R, Lemos PA, von Birgelen C, Christiansen EH, Wijns W, Neumann FJ, Kaiser C, Eeckhout E, Lim ST, Escaned J, Onuma Y, Garcia-Garcia HM, Waksman R. Sustained safety and performance of the second-generation drug-eluting absorbable me-tal scaffold in patients with de novo coronary lesions: 12-month clinical results and angiographic findings of the BIOSOLVE-II first-in-man trial. Eur Heart J. 2016;37:2701-9. Impact Factor 15.064

40. Hillinger P., Twerenbold R., Wildi K., Rubini Gimenez M., Jaeger C., Boeddinghaus J., Nestelberger T., Grimm K., Reichlin T., Stallone F., Pu-elacher C., Sabti Z., Kozhuharov N, Honegger U., Ballarino P., Miro O., Denhaerynck K., Ekrem T., Kohler C., Bingisser R., Osswald S., Mueller C. Gender-specific Uncertainties in the Diagnosis of Acute Coronary Syndro-me. Clin Res Cardiol 2016 Jul 12. Epub ahead of print. Impact factor 4.8

41. Jacob J., Roset A., Mir— ñ., Javier Martín Sanchez P.H.F., Alqu�zar A., Mšckel M., MŸller C., Llorens P. TROPICA-2 Study. Prognostic value of troponin in patients with acute heart failure treated in Spanish hospi-tal emergency services. Biomarkers 2016; Epub ahead of print. Impact Factor 2.016

30. Ferko N, Ferrante G, Hasegawa JT, Schikorr T, Soleas IM, Hernandez JB, Sabat� M, Kaiser C, Brugaletta S, de la Torre Hernandez JM, Galatius S, Cequier A, Eberli F, de Belder A, Serruys PW, Valgimigli M. Cost-effec-tiveness of percutaneous coronary intervention with cobalt-chromium everolimus eluting stents versus bare metal stents: Results from a pati-ent level meta-analysis of randomized trials. Catheter Cardiovasc Interv. 2016 Aug 16 [Epub ahead of print]. Impact Factor 2.181

31. Ferreira JP, Girerd N, Arrigo M, Bettencourt Medeiros P, Bento Ri-cardo M, Almeida T, Rola A, Tolpannen H, Laribi S, Gayat E, Mebazaa A, Mueller C, Zannad, F, Rossignol P, Araga˜o I. Enlarging Red Blood Cell Distribution Width During Hospitalization Identifies a Very High-Risk Subset of Acutely Decompensated Heart Failure Patients and Adds Va-luable Prognostic Information on Top of Hemoconcentration. Medicine 2016;95: (14):e3307. Impact Factor 2.133

32. Forni Ogna V, Ogna A, Ponte B, Gabutti L, Binet I, Conen D, Erne P, Gallino A, Guessous I, Hayoz D, Muggli F, Paccaud F, P�ch�re-Bertchi A, Suter PM, Bochud M, Burnier M. Prevalence and determinants of chronic kidney disease in the Swiss population. Swiss Med Wkly 2016;146:w14313. Impact Factor 1.549

33. Franzone A, Taniwaki M, Rigamonti F, Heg D, Piccolo R, Roffi M, TŸller D, Muller O, Vuilliomenet A, Cook S, Weilenmann D, Kaiser C, Jamshidi P, JŸni P, Windecker S, Pilgrim T. Angiographic complexi-ty of coronary artery disease according to SYNTAX score and clinical outcomes after revascularisation with newer-generation drug-eluting stents: a substudy of the BIOSCIENCE trial. EuroIntervention. 2016 Aug 5;12:e595-604. Impact Factor 3.863

34. Freiermuth D, Mets B, Bolliger D, Reuthebuch O, Doebele T, Scholz M, Gregor M, Haschke M, Seeberger MD, Fassl J. Sevoflurane and Iso-flurane-Pharmacokinetics, Hemodynamic Stability, and Cardioprotective Effects During Cardiopulmonary Bypass. J Cardiothorac Vasc Anesth. 2016 Dec;30(6):1494-1501. doi: 10.1053/j.jvca.2016.07.011. Impact Factor 1.519

35. Garg P., Kidambi A., Swoboda P.P., Foley J.R., Musa T.A., Ripley D.P., Erhayiem B., Dobson L.E., McDiarmid A.K., Fent G.J., Haaf P., Greenwood J.P., Plein S. The role of left ventricular deformation in the assessment of microvascular obstruction and intramyocardial haemor-rhage. Int J Cardiovasc Imaging. 2016 Oct 26. [Epub ahead of print] PMID:27785677. Impact Factor 1.880

42

50. Knecht S, Sticherling C, Reichlin T, MŸhl A, Pavlovic N, Schaer B, Osswald S, KŸhne M. Reliablitiy of luminal oesophageal temperature monitoring during radiofrequency ablation of atrial fibrillation: insights from probe visualization and oesophageal reconstruction using magne-tic resonance imaging Europace 2016 (in press). Impact Factor 4.021

51. Kofler T., Bossard M., Aeschbacher S., Tabord A., Repilado F.J., van der Lely S., Berger S., Risch M., Risch L., Conen D. The interrelationships of birthweight, inflammation and body composition in healthy adults. Eur J Clin Invest 2016;46:342-348. Impact Factor 2.687

52. Kšlm R, Schaller M, Roumenina LT, Niemiec I, Kremer Hovinga JA, Khanicheh E, Kaufmann BA, Hopfer H, Trendelenburg M. Von Wille-brand Factor Interacts with Surface-Bound C1q and Induces Platelet Rolling. J Immunol. 2016 Nov 1;197(9):3669-3679. Impact Factor 4.985

53. Koskinas KC, Taniwaki M, Rigamonti F, Heg D, Roffi M, TŸller D, Mul-ler O, Vuillomenet A, Cook S, Weilenmann D, Kaiser C, Jamshidi P, JŸni P, Windecker S, Pilgrim T. Impact of Patient and Lesion Complexity on Long-Term Outcomes Following Coronary Revascularization With New-Generation Drug-Eluting Stents. Am J Cardiol. 2016 Nov 16 [Epub ahead of print]. Impact Factor 3.154

54. Boeddinghaus J, Reichlin T, Nestelberger T, Twerenbold R, Meili Y, Wildi K, Hillinger P, Rubini Gim�nez M, Cupa J, Schumacher L, Schube-ra M, Badertscher P, Corbi�re S, Grimm K, Puelacher C, Sabti Z, Flores Widmer D, Schaerli N, Kozhuharov N., Shrestha S., Bürge T., MŠchler P., BŸchi M., Rentsch K., Mir— ñ., L—pez B., Martin-Sanchez F.J., Rodriguez-Adrada E., Morawiec B., Kawecki D., Ganovská E., Parenica J., Lohrmann J., Buser A., Keller D.I., Osswald S., Mueller C.. Early Diagnosis of Acute Myocardial Infarction in Patients with Mild Elevations of Cardiac Tropo-nin. Clin Res Cardiol 2016;Epub ahead of print. Impact Factor 4.324

55. Kreutzinger P, Wildi K, Twerenbold R, Rubini Gimenez M, Reichlin T, Jaeger C, Hillinger P, Boeddinghaus J, Nestelberger T, Puelacher C, Stallone F, Rentsch K, Osswald S, Jeger R, Kaiser C, Mueller C. Incidence and Predictors of Cardiomyocyte Injury in Elective Coronary Angiogra-phy. Am J Med. 2016;129(5):537.e1-8. Impact Factor 5.61

56. Krisai P, Leib S, Aeschbacher S, Kofler T, Assadian M, Maseli A, Todd J, Estis J, Risch M, Risch L, Conen D. Relationships of iron metabolism with insulin resistance and glucose levels in young and healthy adults. Eur J Intern Med 2016;32:31-37. Impact Factor 2.59157. Krivoshei L, Weber S, Burkard T, Maseli A, Brasier N, KŸhne M, Co-nen D, Huebner T, Seeck A, Eckstein J. Smart detection of atrial fibrilla-tion. Europace. 2016 Jul 1. pii: euw125. [Epub ahead of print]. Impact Factor 4.021

42. Jaeger C, Wildi K, Twerenbold R, Reichlin T, Rubini Gimenez M, Neuhaus JD, Grimm K, Boeddinghaus J, Hillinger P, Nestelberger T, Singeisen H, Gugala M, Pretre G, Puelacher C, Wagener M, Honegger U, Schumacher U, Moreno Weidmann Z, Kreutzinger P, Krivoshei L, Freese M, Stelzig C, Dietsche S, Ernst S, Rentsch K, Osswald S, Muel-ler C. One-hour rule-in and rule-out of acute myocardial infarction using high-sensitivity cardiac troponin I. Am Heart J. 2016 Jan;171(1):92-102. Impact Factor 4.332

43. Jatene T, Biering-S¿rensen T, Nochioka K, Mangione FM, Hansen KW, S¿rensen R, Jensen JS, Jšrgensen PG, Jeger R, Kaiser C, Pfiste-rer M, Galatius S; BASKET-PROVE Investigators. Frequency of Cardiac Death and Stent Thrombosis in Patients With Chronic Obstructive Pul-monary Disease Undergoing Percutaneous Coronary Intervention (from the BASKET-PROVE I and II Trials). Am J Cardiol. 2016 Sep 29 [Epub ahead of print]. Impact Factor 3.154

44. Jeger R., Pfisterer M., Pfister O., Rickenbacher P., Handke M., Gilgen N., Coslovsky M., Kaier C.. First-generation paclitaxel- vs. second-gene-ration zotarolimus-eluting stents in small coronary arteries: the BASKET-SMALL Pilot Study. Adv Interv Cardio 2016;12:314-20.

45. Jekova I., Krasteva V., Leber R., Schmid R., Twerenbold R., MŸller C., Reichlin T., AbŠcherli R. Intersubject variability and intrasubject repro-ducibility of 12-lead ECG metrics: Implications for human verification. Journal of Electrocardiology 2016;49: 784–789. Impact Factor 1,29.

46. Jekova I., Krasteva V., Leber R., Schmid R., Twerenbold R., MŸller C., Reichlin T., AbŠcherli R. Inter-lead correlation analysis for automated de-tection of cable reversals in 12/16-lead ECG. Comput Methods Programs Biomed. 2016 Oct;134:31-41. Impact Factor 1,86.

47. Jekova I., Krasteva V., Leber R., Schmid R., Twerenbold R., MŸller C., Reichlin T., AbŠcherli R. A Correction Formula for the ST Segment Mea-surements for the AC-coupled Electrocardiograms. IEEE Transactions on Biomedical Engineering 2016;in press. Impact Factor 1,29.

48. Klinkenberg Lieke J.J., Wildi K, van der Linden N, Kouw IWK, Niens M, Twerenbold R, Rubini Gimenez M, Puelacher C, Neuhaus JD, Hillin-ger P, Nestelberger T, Boeddinghaus J , Grimm K, van Suijlen JDE, Tan FES, ten Kate J, Bekers O, van Loon LJC, van Dieijen-Visser MP, Muel-ler C, Meex SJR. A diurnal rhythm of cardiac troponin: consequences for the diagnosis of acute myocardial infarction. Clin Chemistry 2016; Dec;62(12):1602-1611. Impact Factor 7.457

49. Knecht S, Pradella M, Reichlin T, MŸhl A, Bossard M, Stieltjes B, Conen D, Bremerich J, Osswald S, KŸhne M, Sticherling C. Left atrial anatomy, atrial fibrillation burden and P-wave duration � relationships and predictors for single procedure success after pulmonary vein isolati-on. Europace (in press). Impact Factor 4.021 43

Publikationen

10 Publikationen

65. Maeder MT, Zurek M, Rickli H, Tobler D, Kiencke S, Suter T, Yoon SI, Julius B, Pfisterer ME, Brunner-La Rocca HP. Prognostic Value of the Change in Heart Rate From the Supine to the Upright Position in Patients With Chronic Heart Failure. et al. J Am Heart Assoc. 2016;5(8):e003524. Impact Factor 5.117

66. Maisel A., Wettersten N., van Veldhuisen D., Mueller C., Filippatos G., Nowak R., Hogan C., Kontos M.C., Cannon C.M., MŸller G.A., Birk-hahn R., Clopton P., Taub P., Vilke G.M., McDonald K., Mahon N., Nunez J., Briguori C., Passino C., Murray P.T.. The Clinical Value of Neutrophil Gelatinase-Associated lipocalin (NGAL) for Acute Kidney Injury during Hospitalization for Acute Heart Failure: Primary findings for plasma N-gal Acute Kidney Injury N-gal Evaluation of Symptomatic heart faIlure Study (AKINESIS). J Am Coll Cardiol. 2016; 68:1420-31. Impact Factor 17.759

67. Marenzi G., Cosentino N., Boeddinghaus J., Trinei M., Giorgio M., Milazzo V., Moltrasio M. , Cardinale D., Sandri M.T., Veglia F., Bonomi A., Kaech M., Twerenbold R., Nestelberger T., Reichlin T., Wildi K., Shres-tha S., Kohzuharov N., Sabti Z., Cipolla C.M., Mueller C., Bartorelli A.L. Diagnostic and Prognostic Utility of Circulating Cytochrome c in Acute Myocardial Infarction. Circulation Research 2016; Dec 9;119(12):1339-1346. Impact Factor 11.551

68. Marsano A, Medeiros da Cunha CM, Ghanaati S, Gueven S, Centola M, Tsaryk R, Barbeck M, Barbero A, Helmrich U, Schaeren S, Kirkpatrick CJ, Banfi A, Martin I. Spontaneous in vivo chondrogenesis of bone marrow-derived mesenchymal progenitor cells by blocking VEGF signaling. Stem Cells Transl Med. 2016 Jul 26. pii: sctm.2015-0321. Impact Factor 1.884

69. Marsano A*, Conficconi C, Lemme M, Occhetta P, Gaudiello E, Votta E, Cerino G, Redaelli A, Rasponi M*. Beating heart on a chip: a novel micro-fluidic platform to generate functional 3D cardiac microtissues. Lab Chip. 2016 Jan 26;16(3):599-610. *Corresponding Authors. Impact Factor 23.910

70. Marston NA, Shah KS, Mueller C, Neath SX, Christenson RH, Mc-Cord J, Nowak RM, Daniels LB, Hollander JE, Apple F, Nagurney J, Schreiber D, deFilippi C, Diercks D, Limkakeng A, Anand IS, Wu AH, Jaffe AS, Peacock WF, Maisel AS. Serial sampling of copeptin levels im-proves diagnosis and risk stratification in patients presenting with chest pain: results from the CHOPIN trial. Emerg Med J. 2016 Jan;33(1):23-9. Impact factor 1.836

71. Martín-S‡nchez F.J., Rodr’guez-Adrada E., Mueller C., Vid‡n M.T., Christ M., Peacock W.F., Rizzi M.A., Alquezar A., Pi–era P., L‡zaro Aragues P., Llorens P., Herrero P., Jacob J., Fernandez C., Mir— ñ. The effect of frailty on 30-day mortality risk in older patients with acute heart failure attended in the Emergency Department. Acad Emerg Med J. 2016; Oct 31. doi: 10.1111/acem.13124. [Epub ahead of print ]. Impact factor 2.537

58. Kuck KH, Brugada J, FŸrnkranz A, Metzner A, Ouyang F, Chun KR, El-van A, Arentz T,Bestehorn K, Pocock SJ, Albenque JP, Tondo C;FIRE AND ICE Investigators Cryoballoon or radiofrequency ablation for paroxysmal atrial fibrillation N Engl J Med 2016;374:2235-45. Impact Factor 59.558

59. Kuck KH, FŸrnkranz A, Chun KRJ, Metzner A, Ouyang F, SchlŸter M, Elvan A, Lim HW, Kueffer FJ, Arentz T, Albenque JP, Tondo C, KŸhne M, Sticherling C, Brugada J. Cryoballoon or radiofrequency ablation for symptomatic paroxysmal atrial fibrillation; reintervention, rehospitaliza-tion, and quality-of-life outcomes in the FIRE and ICE trial. Eur Heart J 2016; 37:2858-65. Impact Factor 15.064

60. KŸhne M, Knecht S, MŸhl A, Reichlin T, Pavlovic N, Kessel-Schaefer A, Kaufmann BA, Schaer B, Sticherling C, Osswald S. Fluoroscopy-Free Pulmonary Vein Isolation in Patients with Atrial Fibrillation and a Patent Foramen Ovale Using Solely an Electroanatomic Mapping System. PLoS One. 2016 Jan 28;11(1):e0148059. Impact Factor 4.411

61. Lee G, Twerenbold R, Tanglay Y, Reichlin T, Honegger U, Wagener M, Jaeger C, Rubini Gimenez M, Hochgruber T, Puelacher C, Radosavac M, Kreutzinger P, Stallone F, Hillinger P, Krivoshei L, Herrmann T, Mayr R, Freese M, Wild D, Rentsch K, Todd J, Osswald S, Zellweger MJ, Mueller C. Clinical benefit of high-sensitivity cardiac Troponin I in the detection of exercise-induced myocardial ischemia. Am Heart J 2016;173:8-17. Impact Factor 4.463

62. Lindahl B., Jernberg T., Badertscher P., Boeddinghaus J., Eggers K., Frick M., Rubini Gimenez M., Linder R., Ljung L., Martinsson A., Melki D., Nestelberger T., Rentsch K., Reichlin T., Sabti Z., Schubera M., Svensson P., Twerenbold R., Wildi K., Müller C. An algorithm for rule-in and rule-out of acute myocardial infarction using a novel troponin I assay. Heart 2016; Aug 2. pii: heartjnl-2016-309951. doi: 10.1136/heartjnl-2016-309951. [Epub ahead of print]., Impact Factor 5.595

63. Liu K, Wang X, Ntziachristos V, Marsch S, Hunziker P. Polymeric nanosystems for near-infrared multispectral photoacoustic imaging: Synthesis, characterization and in vivo evaluation. European Polymer Journal. Impact Factor 3.485

64. Lopez, R. J., Byrne, S., Vukcevic, M., Sekulic-Jablanovic, M., Xu, L., Brink, M., Alamelu, J., Voermans, N., Snoeck, M., Clement, E., Munto-ni, F., Zhou, H., Radunovic, A., Mohammed, S., Wraige, E., Zorzato, F., Treves, S., and Jungbluth, H. (2016) An RYR1 mutation associated with malignant hyperthermia is also associated with bleeding abnormalities. Sci Signal. Impact Factor 7.359

44

72. Mauermann E., Bolliger D., Seeberger E., Puelacher C., Corbiere S., Fi-lipovic M., Seeberger M., Mueller C., Lurati Buse G. Incremental Value of Preoperative Copeptin for Predicting Myocardial Injury after Non-Cardiac Surgery Anesth Analg. 2016 Dec;123(6):1363-1371. Impact Factor 3.794

73. McCord J., Cabrera R., Lindahl B., Giannitsis E., Evans K., Nowak R., Frisoli T., Body R., Christ M., de Filippi C.R., Christenson R.H., Jacobsen G., Alquezar-Arbe A., Panteghini M., Melki D., Plebani M., Verschuren F., French J., Bendig G., Weiser S., Dilba P., Mueller C. Prognostic Utility of a Modified HEART Score in Acute Chest Pain Patients. Circ Cardiovascu-lar Quality & Outcomes 2016 in press. Impact Factor 17.202

74. McMurray J.J.V., Krum H., Abraham W.T., Dickstein K., Kober L.V., Desai A.S., Solomon S.D., Greenlaw N., Ali A., Chiang Y., Shao Q., Tarnes-by G., Massie B.M for the ATOMOSPHERE Committees Investigators (P. Rickenbacher Investigator). Aliskiren, Enalapril, or Aliskiren and Enalapril in Heart Failure. N Engl J Med 2016;374:1521-32. Impact Factor 59.558

75. Miro O, MŸller C, Martin-Sanchez FJ, Bueno H, Mebazaa A, Herrero P, Jacob J, Gil V, Esconda R, Llorens P. BETAWIN-AHF study: effect of beta-blocker withdrawal during acute decompensation in patients with chronic heart failure. Clin Res Cardiol 2016;Epub ahead of print. Impact Factor 4.560

76. Mueller C, Giannitsis E, Christ,M, Ord—–ez-Llanos J, deFilippi C, Mc-Cord J, Body R, Panteghini M, Jernberg T, Plebani M, Verschuren F, French J, Christenson R, Weiser S, Bendig G, Dilba, P. Lindahl B, for the TRAPID-AMI Investigators. Multicenter Evaluation of a 0h/1h-Algorithm in the Dia-gnosis of Myocardial Infarction Using High-Sensitivity Cardiac Troponin T. Annals of Emergency Medicine 2016Jul;68(1):76-87. Impact Factor 4.695

77. Mueller-Hennessen M, Lindahl B, Giannitsis E, Biener M, Vafaie M, deFilippi CR, Christ M, Santalo-Bel M, Panteghini M, Plebani M, Ver-schuren F, Jernberg T, French JK, Christenson RH, Body R, McCord J, Dilba P, Katus HA, Mueller C; for the TRAPID-AMI Investigators. Age- and Gender-specific Compared to General 99th Percentile Cut-offs for Diagnosis of Myocardial Infarction and Prognostic Implications -Sub-analysis from the TRAPID-AMI (High-sensitivity cardiac Troponin T assay for RAPID rule-out of Acute Myocardial Infarction) Study Int J Cardiol. 2016; Apr 15;209:26-33. Impact Factor 4.638

78. Mueller-Hennessen M., Mueller C., Giannitsis E., Biener M., Vafaie M., deFilippi C.R., Christ M., Ord—–ez-Llanos J., Panteghini M., Plebani M., Verschuren F., Jernberg T., French J.K., Christenson R.H., Body R., McCord J., Dinkel C., Katus H.A., Lindahl B., for the TRAPID-AMI In-vestigators. Serial Sampling of High-Sensitivity Cardiac Troponin T May Not Be Required for Prediction of Acute Myocardial Infarction Diagnosis in Chest Pain Patients with Highly Abnormal Concentrations at Presen-tation. Clin Chemistry 2016; Dec 8. pii: clinchem. 2016.258392. [Epub ahead of print]. Impact Factor 7.457

79. Nestelberger T, Wildi K, Boeddinghaus J, Twerenbold R, Reichlin T, Gim�nez MR, Puelacher C, Jaeger C, Grimm K, Sabti Z, Hillinger P, Kozhuharov N, du Fay de Lavallaz J, Pinck F, Lopez B, Salgado E, Mir— ñ, Bingisser R, Lohrmann J, Osswald S, Mueller C. Characterization of the observe zone of the ESC 2015 high-sensitivity cardiac troponin 0h/1h-algorithm for the early diagnosis of acute myocardial infarction. Int J Cardiol. 2016; Mar 15;207:238-45. Impact Factor 4.638

80. Neumann JT, S¿rensen NA, Schwemer T, Ojeda F, Bourry R, Sciacca V, Schaefer S, Waldeyer C, Sinning C, Renn� T, Than M, Parsonage W, Wildi K, Makarova N, Schnabel RB, Landmesser U, Mueller C, Cullen L, Greenslade J, Zeller T, Blankenberg S, Karakas M, Westermann D. Diag-nosis of Myocardial Infarction Using a High-Sensitivity Troponin I 1-Hour Algorithm. JAMA Cardiology 2016; 2016 Jul 1;1(4):397-404.

81. Ng Leong L., Squire I.B., Jones D.L.J., Cao TH, Daniel C.S. Chan D.C.S., Sandhu J.K., A. Quinn P.A., Davies J.E., Struck J., Hartmann O., Bergmann A., Mebazaa A., Gayat E., Arrigo M., Akiyama E., Sabti Z., Lohrmann J., Twerenbold R., Herrmann T., Schumacher C., Kozhuharov N., Mueller C. Proenkephalin, prediction of renal dysfunction and short and longer term prognosis in acute heart failure - a GREAT network stu-dy. J Am Coll Cardiol. 2016; in press. Impact Factor 17.759

82. Nochioka K, Biering-S¿rensen T, Hansen KW, S¿rensen R, Pedersen S, J¿rgensen PG, Iversen A Shimokawa H, Jeger R, Kaiser C, Pfisterer M andGalatius S; on behalf of the BASKET-PROVE Investigator. Long-term outcomes in patients with rheumatologic disorders undergoing percu-taneous coronary intervention: a Basel Stent Kosten-EffektivitŠtsTrial-PROspective ValidationExamination (BASKET-PROVE) sub-study. Eur Heart J Acute Cardiovasc Care. 2016 May 10. pii: 2048872616649860. [Epub ahead of print].

83. Orwat S, Diller GP, Schmidt R, Tobler D, Greutmann M, Jonkaitiene R, Elnagar A, Johnson MR, Hall R, Roos-Hesseling JW, Baumgartner H; ROPAC Investigators. Risk of Pregnancy in Moderate and Severe Aor-tic Stenosis: From the Multinational ROPAC Registry. J Am Coll Cardiol. 2016;68:1727-37. Impact Factor 17.759

84. Parsonage WA, Mueller C, Greenslade JH, Wildi K, Pickering J, Than M, Aldous S, Boeddinghaus J, Hammett CJ, Hawkins T, Nestelberger T, Reichlin T, Reidt S, Rubin Gimenez M, Tate JR, Twerenbold R, Ungerer JP, Cullen L. Validation of NICE diagnostic guidance for rule out of myo-cardial infarction using high-sensitivity troponin tests. Heart. 2016 Jun 10. pii: heartjnl-2016-309270. doi: 10.1136/heartjnl-2016-309270. Epub ahead of print. Impact Factor 5.693

85. Pavlovic N, Sticherling C, Knecht S, Reichlin T, MŸhl A, Schaer B, Osswald S, KŸhne M. One-year follow-up after irrigated multi-electrode radiofrequency ablation of persistent atrial fibrillation. Europace 2016; 18:85-91. Impact Factor 4.021 45

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10 Publikationen

93. Rubini Gim�nez M., Twerenbold R., Boeddinghaus J., Nestelberger T., Puelacher C., Hillinger P., Wildi K., Jaeger C., Grimm K., Heitzelmann K-F., Sabti Z., Badertscher P., Cupa J., Honegger U., Schaerli N., Kozhuh-arov N., Du Fay de Lavallaz J., Lopez B., Salgado E., Mir— ñ., Martín-Sanchez F.J., Rodríguez Adrada E., Morawiec B. , Parenica J., Ganovska E., Neugebauer C., Rentsch K., Lohrmann J., Osswald S., Reichlin T., Mueller C. Clinical effect of Sex-specific Cut-off Values of High-sensitivi-ty Cardiac Troponin T in Suspected Myocardial Infarction. JAMA Cardio-logy 2016; Nov 1;1(8):912-920.

94. Ruperti Repilado FJ, Aeschbacher S, Bossard M, Schoen T, Gugga-nig R, van der Stouwe JG, Krisai P, Kofler T, Buser A, Risch M, Risch L, Mueller C, Conen D. Relationship of N-Terminal fragment of Pro B-Type Natriuretic Peptide and Copeptin with Erythrocytes-Related Parameters: A Population-Based Study Clinical Biochemistry 2016; Jun;49(9):651-6. Impact Factor 2.382

95. Sanders-van Wijk S., Masson S., Milani V., Rickenbacher P., Gorini M., Tavazzi L. T., Tobler D., Rickli H., Latini R., Brunner-La Rocca H.P. Interaction Of Galectin-3 Concentrations with the Treatment Effects of Β-Blockers and RAS-Blockade In Patients With Systolic Heart Failure: A Derivation-Validation Study from the TIME-CHF and GISSI-HF Trial. Clin Chem. 2016 Apr;62(4):605-16. Impact Factor 7.457

96. Salieb-Beugelaar GB, Goncalves D, Wolf MP, Hunziker P MP. Micro-fluidic 3D Helix Mixers. Micromachines 2016. Impact Factor 1.295

97. Satalkar P, Elger BS, Hunziker P, Shaw D. Challenges of clinical trans-lation in nanomedicine: a qualitative study. Nanomedicine 2016. Impact Factor 4.889

98. Schaer B, Frey S, Sticherling C, Osswald S, Reichlin T, KŸhne M. Per-sistent improvement of ejection fraction in patients with a cardiac resyn-chronization therapy defibrillator correlates with fewer appropriate ICD interventions and lower mortality. Swiss Med Wkly 2016; 146:w14300. Impact Factor 1.549

99. Schaer B, KŸhne M, Reichlin T, Osswald S, Sticherling C. Incidence of and predictors for appropriate implantable cardioverter-defibrillator thera-py in patients with a secondary preventive implantable cardioverter-defib-rillator indication. Europace. 2016 Feb;18(2):227-31. Impact Factor 4.021100. Seegers, J. Conen D., Jung K., Bergau L., Dorenkamp M., LŸthje L., Sohns C., Sossalla S.T., Fischer T.H., Hasenfuss G., Friede T., Zabel M.. Sex difference in appropriate shocks but not mortality during long-term follow-up in patients with implantable cardioverter-defibrillators. Euro-pace 2016;18:1194-1202. Impact Factor 4.021

86. Pentassuglia, L., Heim, P., Lebboukh, S., Morandi, C., Xu, L., and Brink, M. (2016) Neuregulin-1beta promotes glucose uptake via PI3K/Akt in neonatal rat cardiomyocytes. Am J Physiol Endocrinol Metab 310, E782-794. Impact Factor 3.825

87. Piccolo R, Heg D, Franzone A, Roffi M, TŸller D, Vuilliomenet A, Mul-ler O, Cook S, Weilenmann D, Kaiser C, Jamshidi P, Iglesias JF, Winde-cker S, Pilgrim T. Biodegradable-Polymer Sirolimus-Eluting Stents Ver-sus Durable-Polymer Everolimus-Eluting Stents in Patients With Acute ST-Segment Elevation Myocardial Infarction: Insights From the 2-Year Follow-Up of the BIOSCIENCE Trial. JACC Cardiovasc Interv. 2016 May 9;9(9):981-3. Impact Factor 7.63

88. Pilgrim T, Piccolo R, Heg D, Roffi M, TŸller D, Vuilliomenet A, Muller O, Cook S, Weilenmann D, Kaiser C, Jamshidi P, Khattab AA, Taniwaki M, Rigamonti F, Nietlispach F, Blšchlinger S, Wenaweser P, JŸni P, Win-decker S. Biodegradable polymer sirolimus-eluting stents versus durable polymer everolimus-eluting stents for primary percutaneous coronary revascularisation of acute myocardial infarction. EuroIntervention. 2016 Dec 10;12(11):e1343-e135. Impact Factor 3.863

89. Pilgrim T, Stortecky S, Nietlispach F, Heg D, Tueller D, Toggweiler S, Ferrari E, Noble S, Maisano F, Jeger R, Roffi M, GrŸnenfelder J, Huber C, Wenaweser P, Windecker S. Repositionable Versus Balloon-Expandable Devices for Transcatheter Aortic Valve Implantation in Patients With Aor-tic Stenosis. J Am Heart Assoc. 2016 Nov 17;5(11). pii: e004088. Impact Factor 4.306

90. Radosavac M., Twerenbold R., Wagener M., Honegger U., Puelacher C., Wildi K., Reichlin T., Kreutzinger P., Stallone F., Hillinger P., Jaeger C., Rubini Gimenez M., Shrestha S., Heberer M., Kuehne M., Osswald S., Mueller C. A novel quality indicator for the treatment of acute myocardial infarction: feasibility and first results. Cardiovasc Medicine 2016; 19(7-8):211-216.

91. Raman K, Aeschbacher S, Bossard M, Hochgruber T, Zimmermann AJ, Kaufmann BA, Pumpol K, Rickenbacker P, Par� G, Conen D. Whole Blood Gene Expression Differentiates between Atrial Fibrillation and Si-nus Rhythm after Cardioversion. PLoS One. 2016 Jun 22;11(6):e0157550. doi: 10.1371/journal.pone.0157550. Impact Factor 4.411

92. Reichlin T, Lockwood SJ, Conrad MJ, Nof E, Michaud GF, John RM, Epstein LM, Stevenson WG, Jarolim P. Early release of high-sensitive cardiac troponin during complex catheter ablation for ventricular tachy-cardia and atrial fibrillation. J Interv Card Electrophysiol. 2016 Mar 12. Impact Factor 1.676

46

101. Shende P, Xu L, Morandi C, Pentassuglia L, Heim P, Lebboukh S, Berthonneche C, Pedrazzini T, Kaufmann BA, Hall MN, RŸegg MA, Brink M.Cardiac mTOR complex 2 preserves ventricular function in pressure-overload hypertrophy. Cardiovasc Res. 2016;109(1):103-14. Impact Fac-tor 5.465

102. Shulga D, Morozov O, Hunziker P. A Tensor B-Spline Approach for Solving the Diffusion PDE With Application to Optical Diffusion Tomogra-phy. IEEE Transactions on Medical Imaging 2016. Impact Factor 3.756

103. Silvetti S, Crivellari M, Castiglioni A, Landoni G, Zangrillo A, Alfi-eri O, Koster A, Faraoni D, Bolliger D, Tanaka KA. CASE 12-2016 As-cending Aorta Dissection in a Jehovah‘s Witness Patient on Warfarin. J Cardiothorac Vasc Anesth. 2016 Dec;30(6):1709-1715. doi: 10.1053/j.jvca.2016.02.029. No abstract available. Impact Factor 1.519

104. Sou SM, Puelacher C, Twerenbold R, Wagener M, Honegger U, Reichlin T, Schaerli N, Pretre G, AbŠcherli R, Jaeger C, Rubini Gimenez M, Wild D, Rentsch KM, Zellweger MJ, Mueller C. Direct comparison of cardiac troponin I and cardiac troponin T in the detection of exercise-induced myocardial ischemia. Clinical Biochemistry 2016 Apr;49(6):421-32. Impact Factor 2.382

105. Staempfli R, Schmid JP, Schenker S, Eser P, Trachsel LD, Delu-igi C, Wustmann K, Thomet C, Greutmann M, Tobler D, Stambach D, Wilhelm M, Schwerzmann Cardiopulmonary adaptation to short-term high altitude exposure in adult Fontan patients M. Heart 2016;0:1-6. doi:10.1136/heartjnl-2016-309682. Impact Factor 5.693

106. Stallone F, Schoenenberger AW, Puelacher C, Rubini Gimenez M, Walz B, Naduvilekoot Devasia A, Bergner M, Twerenbold R, Wildi K, Reichlin T, Hillinger P, Erne P, Mueller C. Incremental value of copep-tin in suspected acute myocardial infarction very early after symp-tom onset. Eur Heart J Acute Cardiovasc Care 2016 2016 Mar 24. pii: 2048872616641289.

107. Staub D, Partovi S, Zeller T, Breidthardt T, Kaech M, Boeddinghaus J, Puelacher C, Nestelberger T, Aschwanden M, Mueller C. Multimarker Assessment for the Prediction of Renal Function Improvement After Per-cutaneous Revascularization for Renal Artery Stenosis. Cardiovascular Diagnosis and Therapy 2016; in press.

108. Steinl M, Xu L, Khanicheh E, Ellertsdottir E, Ochoa-Espinosa A, Mit-terhuber M, Glatz K, Kuster GM, Kaufmann BA. Non-invasive contrast enhanced ultrasound molecular imaging detects myocardial inflamm-atory response in autoimmune myocarditis. Circ Cardiovasc Imaging. 2016 Aug;9(8). pii: e004720. Impact Factor 5.744

109. Sticherling C, Menafoglio A, Burri H, ReeK S, Fuhrer J, Gani�re V, Zimmerli M, Babotai I, Duru F, Pruvot E, Seeberger M, Kindler C, Basciani R, Vogt A, Eberle B, Marcucci C, Ecknauer E, Bollinger D. Recommenda-tions for the perioperative management of patients with cardiac implan-table devices. Cardiovasc Med 2016;19:13-18.

110. Swoboda P.P., McDiarmid A.K., Erhayiem B., Haaf P., Kidambi A., Fent G.J., Dobson L.E., Musa T.A., Garg P., Law G.R., Kearney M.T., Barth J.H., Ajjan R., Greenwood J.P., Plein S. A Novel and Practical Screening Tool for the Detection of Silent Myocardial Infarction in Patients With Type 2 Diabetes. J Clin Endocrinol Metab. 2016 Sep;101(9):3316-23. doi: 10.1210/jc.2016-1318. PMID:27300573. Impact Factor 5.531

111. Tolppanen H, Siirila-Waris K, Harjola VP, Marono D, Parenica J, Kreutzinger P, Nieminen T, Pavlusova M, Tarvasmaki T, Twerenbold R, Tolonen J, Miklik R, Nieminen MS, Spinar J, Mueller C, Johan Lassus J. Ventricular conduction abnormalities as predictors of long-term survival in acute de novo and decompensated chronic heart failure. ESC Heart Failure 2016 Mar;3(1):35-43. Impact Factor 1.14

112. Twerenbold R, Jaeger C, Rubini Gim�nez M, Wildi K, Reichlin T, Nest-elberger T, Boeddinghaus J, Grimm K, Puelacher C, Moehring B, Pretre G, Schaerli N, Campodarve I, Rentsch K, Steuer S, Osswald S, Mueller C. Im-pact of high-sensitivity cardiac troponin on use of coronary angiography, cardiac stress testing and time to discharge in suspected acute myocardi-al infarction. Eur Heart J 2016; Epub ahead of print. Impact Factor 15.064

113. Vafaie M, Slagman A, Möckel M, Hamm C, Huber K, MŸller C, Vollert JO, Blankenberg S, Katus HA, Liebetrau C, Giannitsis E, Searle J. Prog-nostic value of undetectable hs troponin T in suspected acute coronary syndrome. Am J Med. 2016 Mar;129(3):274-82.e2. Impact Factor 5.61

114. Vanderberk B, Garweg C, Voros G, Flore V, Marynissen T, Sticher-ling C, Zabel M, Ector J, Willems R. Changes in implantation patterns and therapy rates of implantable cardioverter-defibrillators over time in ischemic and dilated cardiomyopathy patients. Pacing Clin Electrophysi-ol 2016;39:848-57. Impact Factor 1.44

115. Vanniyasingam T, Rodseth RN, Lurati Buse GA, Bolliger D, Burkhart CS, Cuthbertson BH, Gibson SC, Mahla E, Leibowitz DW, Biccard BM, Thabane L. Predicting the occurrence of major adverse cardiac events within 30 days of a vascular surgery: an empirical comparison of the minimum p value method and ROC curve approach using individual pa-tient data meta-analysis. Springerplus. 2016 Mar 9;5:304. doi: 10.1186/s40064-016-1936-8. Impact Factor 0.982

47

Publikationen

10 Publikationen

123. Wildi K., Nelles B., Twerenbold R., Maria Rubini Gim�nez, Tobias Reichlin, H�l�ne Singeisen, Sophie Druey, Philip Haaf, Zaid Sabti, Hillinger P. , Jaeger C., Campodarve I., Kreutzinger P., Puelacher C., Moreno Weid-mann Z., Gugala M., Pretre G., Doerflinger S., Wagener M., Stallone F., Freese M., Stelzig C., Rentsch K., Bassetti S, Bingisser R., Osswald S., Mu-eller C. Safety and Efficacy of the 0h/3h-protocol for rapid rule-out of Myo-cardial Infarction. Am Heart J. 2016; Nov;181:16-25. Impact Factor 4.463

124. Woehrle D, Martinez M, Bolliger D. Hereditary heterozygous factor VII deficiency in patients undergoing surgery : Clinical relevance. Anaes-thesist. 2016 Oct;65(10):746-754. Impact Factor 0.964

125. Wolfrum M, Fahrni G, de Maria GL, Knapp G, Curzen N, Kharbanda RK, Fršhlich GM, Banning AP. Impact of impaired fractional flow reser-ve after coronary interventions on outcomes: a systematic review and meta-analysis. BMC Cardiovasc Disord. 2016 Sep 8;16(1):177. Impact Factor 2.021

126. Zbinden R, Piccolo R, Heg D, Roffi M, Kurz DJ, Muller O, Vuilliome-net A, Cook S, Weilenmann D, Kaiser C, Jamshidi P, Franzone A, Eberli F, JŸni P, Windecker S, Pilgrim T. Ultrathin Strut Biodegradable Polymer Sirolimus-Eluting Stent Versus Durable-Polymer Everolimus-Eluting Stent for Percutaneous Coronary Revascularization: 2-Year Results of the BIOSCIENCE Trial. J Am Heart Assoc. 2016 Mar 15;4(3):e003255. doi: 10.1161/JAHA.116.003255. Impact Factor 4.306

127. Zbinden R, von Felten S, Wein B, Tueller D, Kurz DJ, Reho I, Galatius S, Alber H, Conen D, Pfisterer M, Kaiser C, Eberli FR. Impact of stent diameter and length on in-stent restenosis after DES vs BMS implantati-on in patients needing large coronary stents - a clinical and health-eco-nomic evaluation. Cardiovasc Ther. 2016 Sep 23 [Epub ahead of print]. Impact Factor 2.243

Reviews & Editorials

1. 2016 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure: The Task Force for the diagnosis and treatment of acute and chronic heart failure of the European Society of Cardiology (ESC). Developed with the special contribution of the Heart Failure As-sociation (HFA) of the ESC. Authors/Task Force Members; Document Reviewers. Eur J Heart Fail. 2016 May 20. doi: 10.1002/ejhf.592. [Epub ahead of print]. Impact Factor 5.135

116. Vassalli G, Klersy C, De Servi S, Galatius S, Erne P, Eberli F, Rickli H, Hornig B, Bertel O, Bonetti P, Moccetti T, Kaiser C, Pfisterer M, Pedrazzini G; BASKET-PROVE Investigators. Can the optimal type of stent be predic-ted based on clinical risk factors? A subgroup analysis of the randomized BASKET-PROVE trial. Am Heart J. 2016;173:1-7. Impact Factor 4.332

117. Volosyuk VK, Zhyla SS, Kravchenko VF, Morozov AV, Pustovoit VI, Huniker P. Method of holographic imaging of inhomogeneities in the density of a substance of a semitransparent medium using plane-parallel laser radiation. Doklady Physics. Impact Factor 0.513

118. von Gunten S, Schaer BA, Yap SC, Szili-Torok T, KŸhne M, Sticher-ling C, Osswald S, Theuns DA. Longevity of implantable cardioverter de-fibrillators: a comparison among manufacturers and over time. Europace 2016;18:710-7. Impact Factor 4.021

119. von Rotz M, Aeschbacher S, Bossard M, Schoen T, Blum S, Schnei-der S, Estis J, Todd J, Risch M, Risch L, Conen D. Risk factors for prema-ture ventricular contractions in young and healthy adults. Heart. 2016. Epub ahead of print. Impact Factor 5.693

120. Wagener M.; AbŠcherli R.; Honegger U.; SchŠrli N.; Pr�tre G., Twe-renbold R., Puelacher C., Sunier G., Reddiess P., Rubini Gimenez M., Wil-di K., Boeddinghaus J., Nestelberger T., Badertscher P., Sabti Z., Schmid R., Leber R., Flores Widmer D., Shrestha S., Strebel I., Wild D., Osswald S., Zellweger M., Mueller C., Reichlin T. Diagnostic and prognostic value of lead aVR during exercise testing. Am J Cardiol 2016; in press. Impact Factor 3.276

121. Wienbergen H*, Pfister O*, Hochadel M, Michel S, Bruder O, Remp-pis BA, Maeder MT, Strasser R, von Scheidt W, Pauschinger M, Senges J, Hambrecht R; Usefulness of Iron Deficiency Correction in Manage-ment of Patients With Heart Failure [from the Registry Analysis of Iron Deficiency-Heart Failure (RAID-HF) Registry]. RAID-HF (Registry Analy-sis of Iron Deficiency–Heart Failure) REGISTRY Study Group.*equal con-tribution. Am J Cardiol. 2016 Dec 15;118(12):1875-1880. doi: 10.1016/j.amjcard.2016.08.081. Impact Factor 3.154

122. Wildi K, Twerenbold R, Jaeger C, Rubini Gim�nez M, Reichlin T, Stoll M, Hillinger P, Puelacher C, Boeddinghaus J, Nestelberger T, Grimm K, Grob M, Rentsch K, Arnold C, Mueller C. Clinical impact of the 2010-2012 low-end shift of high-sensitivity cardiac troponin T. Eur Heart J Acute Car-diovasc Care. 2016 Apr 7. pii: 2048872616642952. [Epub ahead of print]

48

2. 2016 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure: The Task Force for the diagnosis and treatment of acute and chronic heart failure of the European Society of Cardiology (ESC) Developed with the special contribution of the Heart Failure As-sociation (HFA) of the ESC. Ponikowski P, Voors AA, Anker SD, Bueno H, Cleland JG, Coats AJ, Falk V, González-Juanatey JR, Harjola VP, Jan-kowska EA, Jessup M, Linde C, Nihoyannopoulos P, Parissis JT, Pieske B, Riley JP, Rosano GM, Ruilope LM, Ruschitzka F, Rutten FH, van der Meer P; Authors/Task Force Members; Document Reviewers. Eur Heart J. 2016 May 20. pii: ehw128. [Epub ahead of print]. Impact Factor 15.064

3. Attenhofer Jost Ch., Tobler D, Greutmann M. Pulmonalatresie. Herz-blatt Ausgabe 04/2016.

4. Bolliger D, Tanaka KA. Fibrinogen-is it a universal haemostatic agent? Br J Anaesth. 2016 Nov;117(5):548-550. No abstract available. Impact Factor 5.616

5. Bolliger D, Zenklusen U, Tanaka KA. Point-of-care coagulation ma-nagement algorithms during ECMO support: are we there yet? Minerva Anestesiol. 2016 Mar 30. [Epub ahead of print]. Impact Factor 2.036

6. Donner B, HŠffner N, Dechant M, Thomet C, Pfammatter JP, Tobler D. Transition Jugendlicher mit einer angeborenen Herzerkrankung. Cardio-Vasc 2016, Vol. 15, Nr. 5.

7. Gon�alves D, Hunziker P. Transmission-blocking strategies: the road-map from laboratory bench to the community. Malaria journal 15 (1), 95. Impact Factor 3.03

8. Greutmann M, Tobler D.Health insurance problems for adults with congenital heart disease. Eur Heart J. 2016 vol 37(18). Impact Factor 15.064

9. Haaf P, Garg P, Messroghli DR, Broadbent DA, Greenwood JP, Plein S. Cardiac T1 Mapping and Extracellular Volume (ECV) in clinical practi-ce: a comprehensive review. J Cardiovasc Magn Reson. 2016 Nov 30;18(1):89. Review. PMID:27899132. Impact Factor 5.752

10. Harjola VP, Mebazaa A, Celutkien� J, Bettex D, Chioncel O, Falk V, Fi-lippatos GS, Gibbs S, Leite-Moreira A, Lassus J, Masip J, Mueller C, Mul-lens W, Naeje R, Nordegraaf AV, Parissis J, Riley J, Ristic A, Rosano G, Rudiger A, Ruschitzka F, Seferovic P, Sztrymf B, Vieillard-Baron A, Yilmaz M, Konstantinides S. Contemporary Management of Acute Right Ven-tricular Failure: A Statement from the Heart Failure Association and the Working Group on Pulmonary Circulation and Right Ventricular Function of the European Society of Cardiology European Journal of Heart Failure. Eur J Heart Fail. 2016;18:226-41. Impact Factor 5.135

11. Hollander JE, Than M, Mueller C. State-of-the-Art Evaluation of Emer-gency Department Patients Presenting With Potential Acute Coronary Syndromes. Circulation. 2016 Aug 16;134(7):547-64. Impact factor 17.047

12. Hunziker P. Nanomedicine translation from enabling technologies to the patient: focus on infectious diseases. European Journal of Nanome-dicine Impact Factor 0.64

13. Kuster GM, Liao R. Fortune favors the prepared: Safety and efficacy of allogeneic hypoxia preconditioned mesenchymal stromal cells in pri-mates. Circ Res 2016;118:908-910. Impact Factor 11.6

14. Liu K, Jiang X, Hunziker P. Carbohydrate-based amphiphilic nano delivery systems for cancer therapy. Nanoscale 16091-16156. Impact Factor 7.76

15. Maeder MT, Mueller C, Schoch OD, Ammann P, Rickli H. Biomarkers of Cardiovascular Stress in Obstructive Sleep Apnea. Clin Chim Acta. 2016 Jul 2;460:152-163. doi: 10.1016/j.cca.2016.06.046. [Epub ahead of print] Review. Impact Factor 2.799

16. Mair J, Lindahl B, Giannitsis E, Huber K, Thygesen K, Plebani M, Mšckel M, MŸller C, Jaffe AS; Biomarker Study Group of the European Society of Cardiology Acute Cardiovascular Care Association. Will sacu-bitril-valsartan diminish the clinical utility of B-type natriuretic peptide testing in acute cardiac care? Eur Heart J Acute Cardiovasc Care. 2016 Jan 12. pii: 2048872615626355. [Epub ahead of print]

17. Mart’n-S‡nchez FJ, Christ M, Mir— ñ, Peacock WF, McMurray JJ, Bueno H, Maisel AS, Cullen L, Cowie MR, Di Somma S, Platz E, Masip J, Zeymer U, Vrints C, Price S, Mueller C. Practical approach on frail older patients attended for acute heart failure. Int J Cardiol. 2016 Nov 1;222:62-71. Impact factor 4.638

18. Mebazaa A, Tolppanen H, Mueller C, Lassus J, DiSomma S, Bak-syte G, Cecconi M, Choi DJ, Cohen Solal A, Christ M, Masip J, Arrigo M, Nouira S, Ojji D, Peacock F, Richards M, Sato N, Sliwa K, Spinar J, Thiele H, Yilmaz MB, Januzzi J. Acute heart failure and cardiogenic shock: a multidisciplinary practical guidance. Intensive Care Med. 2016 Feb;42(2):147-63. Impact Factor 7.422

19. Miro O, Peacock FW, Christ M, Cowie M, Cullen L, Maisel AS, Ma-sip J, Miro O, McMurray J, Peacock FW, Price S, DiSomma S, Bueno H, Zeymer U, Mebazaa A, Mueller C. European Society of Cardiolo-gy - Acute Cardiovascular Care Association position paper on safe di-scharge of acute heart failure patients from the emergency department. European Heart Journal: Acute Cardiovascular Care 2016; Feb 21. pii: 2048872616633853. [Epub ahead of print]. Impact Factor 15.064

49

Publikationen

10 Publikationen

27. Rutz T, Wustmann K, Prsa M, Vall�e JP, Donner B, Bremerich J, De-luigi C, Zellweger M, Tobler D, Kellenberger C, Wahl A, Monney P, Buser P, Gudinchet F, Schwitter J, Valsangiacomo BŸchel E. Cardiac magenetic resonance imaging in congenital heart disease. Cardiovascular Medici-ne. 2016;19(06):176-184.

28. Salieb-Beugelaar GB, Zhang B, Nigo MM, Frischmann S, Hunziker P. Improving diagnosis of pneumococcal disease by multiparameter tes-ting and micro/nanotechnologies. European Journal of Nanomedicine 8 (3), 115-128. Impact Factor 0.64

29. Shulga D, Morozov O, Hunziker P. A Tensor B-Spline Approach for Solving the Diffusion PDE With Application to Optical Diffusion Tomo-graphy. IEEE Transactions on Medical Imaging 2016.

30. Tobler D, Peterli Wolf B. herznetz.ch - Verbesserung der Wahrneh-mung und Verbreitung von Informationen. Herzblatt Ausgabe 04/2016.

31. Vargas KG, Kassem M, Mueller C, Wojta J, Huber K. Copeptin for the Early Rule-out of Non-ST-elevation Myocardial Infarction. Int J Cardiol 2016; Nov 15;223:797-804. Impact factor 4.638

32. Visone R, Gilardi M, Marsano A, Rasponi M, Bersini S, Moretti M. Cardiac Meets Skeletal: What‘s New in Microfluidic Models for Musc-le Tissue Engineering. Molecules. 2016 Aug 26;21(9). pii: E1128. doi: 10.3390/molecules21091128. Review. Impact Factor 4.465

33. Xu, L., and Brink, M. (2016) mTOR, cardiomyocytes and inflamma-tion in cardiac hypertrophy. Biochim Biophys Acta Impact Factor 5.34

34. Zhang B, Hunziker P. Cost-effectiveness: A challenge for dengue ra-pid nanodiagnostic tests. Nanomedicine 2016 Jan; 12(19):251-2. Impact Factor Impact Factor 4.889

Letters to the editor

1. Badertscher P, du Fay de Lavallaz J, Mueller C. Prevalence of pulmo-nary embolism among patients hospitalized for syncope. N Engl J Med 2016;in press. Impact factor 59.558

2. Boeddinghaus J, Twerenbold R, Nestelberger T, Wildi K, Mueller C. Measurement of high-sensitivity cardiac troponin for exclusion of myo-cardial infarction. Lancet 2016; Vol 387 June 4, 2016, 2288. Impact fac-tor 44.002

3. Kohzuharov N, Sabti Z, Mueller C. Nitrates in the treatment of heart fai-lure with preserved ejection fraction. N ENgl J Med 2016;374(16):1588-9. Impact Factor 59.558

20. Mont L, Pelliccia A, Sharma S, Biffi A, Borjesson M, Brugada Terra-dellas J, Carr� F, Guasch E, Heidbuchel H, La Gerche A, Lampert R, McKenna W, Papadakis M, Priori SG, Scanavacca M, Thompson P, Sticherling C, Viskin S, Wilson M, Corrado D; Reviewers., Lip GY, Go-renek B, Blomstršm Lundqvist C, Merkely B, Hindricks G, Hern‡ndez-Madrid,Lane D, Boriani G, Narasimhan C, Marquez MF, Haines D, Mackall J, Manuel Marques-Vidal P, Corra U, Halle M, Tiberi M, Niebauer J, Piepoli M. Pre-participation cardiovascular evaluation for athletic parti-cipants to prevent sudden cardiac death: Position paper from the EHRA and the EAPCR, branches of the ESC. Endorsed by APHRS, HRS , and SOLACE. Eur J Prev Cardiol 2017;24:41-69. Impact Factor 3.361

21. Mšckel M, Giannitsis E, Mueller C, Huber K, Jaffe AS, Mair J, Ple-bani M, Thygesen K, Lindahl B; Biomarker Study Group of the European Society of Cardiology Acute Cardiovascular Care Association. Rule-in of acute myocardial infarction: Focus on troponin. Eur Heart J Acute Cardi-ovasc Care. 2016 Jun 2. pii: 2048872616653228. [Epub ahead of print.

22. Mueller C, Giannitsis E, Mšckel M, Huber K, Mair J, Plebani M, Thy-gesen K, Jaffe AS, Lindahl B; Biomarker Study Group of the ESC Acute Cardiovascular Care Association. Rapid rule out of acute myocardial in-farction: novel biomarker-based strategies.Eur Heart J Acute Cardiovasc Care. 2016 Jul 1. pii: 2048872616653229. [Epub ahead of print]

23. Mueller C, Patrono C, Roffi M. Background, fundamental concepts, and scientific evidence of the high-sensitivity cardiac troponin 0h/1h-algorithm for early rule-out or rule-in of acute myocardial infarction. Eur Heart J. 2016; Epub ahead of print. Impact Factor 15.064

24. Murray K and Burkard T. [Hyperuricemia, gout and cardiovascular diseases]. Ther Umsch. 2016;73:141-6.

25. Ramakrishna H, Gutsche JT, Patel PA, Evans AS, Weiner M, Morozo-wich ST, Gordon EK, Riha H, Bracker J, Ghadimi K, Murphy S, Spitz W, MacKay E, Cios TJ, Malhotra AK, Baron E, Shaefi S, Fassl J, Weiss SJ, Silvay G, Augoustides JG. The Year in Cardiothoracic and Vascular Anes-thesia: Selected Highlights from 2016. J Cardiothorac Vasc Anesth. 2016 Oct 14. pii: S1053-0770(16)30498-0. doi: 10.1053/j.jvca.2016.10.009. [Epub ahead of print] Review. Impact Factor 1.519

26. Roffi M, Patrono C, Collet JP, Mueller C, Valgimigli M, Andreotti F, Bax JJ, Borger MA, Brotons C, Chew DP, Gencer B, Hasenfuss G, Kjeld-sen K, Lancellotti P, Landmesser U, Mehilli J, Mukherjee D, Storey RF, Windecker S. 2015 ESC Guidelines for the management of acute coro-nary syndromes in patients presenting without persistent ST-segment elevation. Task Force for the Management of Acute Coronary Syndro-mes in Patients Presenting without Persistent ST-Segment Elevation of the European Society of Cardiology (ESC)]. G Ital Cardiol (Rome). 2016 Oct;17(10):831-872. doi: 10.1714/2464.25804.

50

4. Mueller C, Giannitsis E, Lindahl B. TRAPID-AMI In reply. Ann Emerg Med. 2016 Jun;67(6):794-5. doi: 10.1016/j.annemergmed.2016.02.037.

5. Zellweger MJ. The complex principle of cause and effect. J Nucl Car-diol. 2016 May 4. [Epub ahead of print] No abstract available. PMID: 27146886

Case reports

1. Celikyurt U, Sticherling C, Reichlin T, Schaer B, Osswald S, KŸhne M. Wolff-Parkinson-White syndrome and diverticulosis of the heart? Cardio-vasc Med 2016;19:34-36. Impact Factor 1.658

2. D‘Antico C, Hofer A, Fassl J, Tobler D, Zumofen D, Goettel N. Case Report: Emergency awake craniotomy for cerebral abscess in a patient with unrepaired cyanotic congenital heart disease F1000Research 2016; 5:2521. F1000Res. 2016 Oct 14;5:2521

3. D‘Antico C, Hofer A, Fassl J, Tobler D, Zumofen D, Goettel N. Emer-gency awake craniotomy for cerebral abscess in a patient with unre-paired cyanotic congenital heart disease.

4. Dayal N, Burri H, Sticherling C, Auricchio A. The subcutaneous im-plantable cardioverter-defibrillator: pros and cons. Cardiovasc Med 2016;19:121-127. Impact Factor 1.658

5. Heid J, Vogel B, Kristen A, Kloos W, Kohler B, Katus HA, Korosoglou G. Interventional treatment of the left subclavian in 2 patients with coro-nary steal syndrome. World J Cardiol 2016; In press

6. Knecht S, Novak J, Kühne M. Entrapment of a diagnostic catheter in a novel multipolar basket catheter (Orion) during right atrial mapping. Europace 2016; 18:1186. Impact Factor 4.021

7. Knecht S, Spies F, Altmann D, Reichlin T, Sticherling C, KŸhne M. Electroanatomic Mapping of Atrial Tachycardia-Manual vs. Automated Annotation. Man versus Machine. Heart Rhythm Case Report accepted

8. Kopp S, Kiencke S, Sticherling C, Reichlin T. Recurrent symptomatic re-gular tachycardia. Cardiovasc Med 2016;19:185-187. Impact Factor 1.658

9. Kuenzli E1, Labhardt N2, Balestra G3, Weisser M4, Zellweger MJ5, Blum J2. Staphylococcus aureus Endocarditis as a Complication of Toxocariasis-Associated Endomyocarditis With Fibrosis: A Case Report.

10. Mauermann E, Vškt C, Tsakiris DA, Tobler D, Girard T. Heparin-in-duced thrombocytopenia in pregnancy: an interdisciplinary challenge-a case report and literature review. Int J Obstet Anesth. 2016 May;26:79-82. Impact Factor 2.04

11. Reichlin T, AbŠcherli R, Twerenbold R, Kühne M, Schaer B, Mueller C, Sticherling C, Osswald S. Advanced ECG in 2016 and beyond: is there more than just a tracing? Swiss Med Wkly 2016; 146:w14303. Impact Factor 1.459

12. Reichlin T, KŸhne M, Sticherling C. Repetitive inappropriate implan-table cardioverter-defibrillator shocks due to insulation failure with ex-ternalized conductor cables of a Biotronik Linox SD ICD lead. Europace. 2016 May;18(5):686. Impact Factor 4.021

13. Schšn, KŸhne M. Vorhofflimmern. Ther Umsch. 2016;73(6):333-9.

14. Sticherling C, KŸhne M. Pulmonary vein isolation without assessing pulmonary vein potentials - not there yet. Heart Rhythm 2016 (epub). Impact Factor 4.391

15. Sticherling C. Methadon und QTc-VerlŠngerung - eine versteckte Ge-fahr. Swiss Medical Forum 2016;16:157

16. Sticherling C. Pulmonary vein isolation: Is our target the one we think? Heart Rhythm 2016; 13:1358-9. Impact Factor 4.391

17. v. Gunten S, Crevoisier JL, KŸhne M, Reichlin T, Osswald S, Sticher-ling C, Schaer B. To explant, or not to explant, that is the question. Car-diovasc Med 2016; 19:237-238. Impact Factor 1.658

Books / Book chapters

1. Herzog B, Plein S, Greenwood J, Co-authors: Garg P, Haaf P. ESC CMR pocket guide - Endorsed by the working group on CMR of the European Society of Cardiology (ESC). www.cmr-guide.com, (Version 3.0 2016)

2. Kuster GM, Della Verde G, Liao R, Pfister O. Cell Therapy for Cardiac Regeneration. In: J. Laurence, M. Van Beusekom, P. Baptista, A. Atala, eds. Translating Regenerative Medicine to Clinics. United States of Ame-rica: Academic Press, Elsevier Inc., 2016; pp. 266-283.

3. Vischer AS and Burkard T. Principles of Blood Pressure Measurement - Current Techniques, Office vs Ambulatory Blood Pressure Measure-ment. Adv Exp Med Biol. 2016.

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Auszeichnungen

Habilitationen

Beat SchŠr: Titularprofessur

Dissertationen

Dissertationen bei Prof. Christian MŸller

Dr. Bourtzou Anna: Diagnostic and prognostic value of ST - seg-ment deviation scores in suspected acute myocardial infarction

Dr. Cesal Martina: Direct comparison of B-type natriuretic pepti-de and midregional pro-atrial natriuretic peptide in the diagnosis of acute heart failure

Dr. Druey Sophie: Early rule-out and rule-in of myocardial infarc-tion using sensitive cardiac Troponin I

Dr. Eisenhut Timo: Complement Factors in Acute Heart Failure: Potential Role in Pathophysiologiy, Response to Treatment and Impact on long-term Survival

Dr. Engels Ulrike: Optimizing early rule-out strategies for NSTE-MI: utility of a second measurement of high-sensitivity cardiac troponin T or Copeptin at one hour

Dr. Fischer Catherine Marie-Madeleine: Risk-stratification in pa-tients with acute chest pain using three high-sensitivity cardiac troponin assays

Dr. Fischer Clarissa Felicitas: Cardiomyocyte injury induced by hemodynamic cardiac stress: differential release of cardiac bio-markers

Dr. Heitzelmann Karl-Frieder: Clinical Impact of Sex-specific Cutt- off Values of High-sensitivity Cardiac Troponin T in Suspected Myocardial Infarction

11 Auszeichnungen

Dr. Kern Anklin Vera: 2h-algorithm for triage towards "rule-out“" and "rule-in" of acute myocardial infarction using high-sensitivi-ty cardiac troponin I

Dr. Lee Gino: Clinical benefit of high-sensitivity cardiac Troponin I in the detection of exercise-induced myocardial ischemia

Dr. Marono David: VentrikulŠre Reizleitungsstšrungen als PrŠ-diktoren von LangzeitŸberleben in akuter Herzinsuffizienz

Dr. Merki Ramona Olivia: Incremental value of Copeptin for Ra-pid Rule Out of Acute Myocardial Infarction

Dr. Nestelberger Thomas: Characterization of the observe zone of the ESC 2015 high-sensitivity cardiac troponin 0 h/1 h-algo-rithm for the early diagnosis of acute myocardial infarction

Dr. Neuhaus Jean-Daniel: A diurnal rhythm of cardiac troponin: consequences for the diagnosis of acute myocardial infarction

Dr. Sou Seoung Mann: Direct comparison of cardiac Troponin I and cardiac Troponin T in the detection of exercise-induced myocardial ischemia

Dr. Stoll Melanie Patricia: Clinical impact of the 2010-2012 low-end shift of high-sensitivity cardiac troponin T

Dr. Walukiewicz Astrid Nicole: Optimal Cut-off Levels of More Sensitive Cardiac Troponin Assays for the Early Diagnosis of Myocardial Infarction in Patients with Renal Dysfunction

Dr. ZŸrcher Stephan Michael: Delayed release of brain natriure-tic peptide to identify myocardial ischemia

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Dissertationen bei Prof. David Conen

Dr. Kofler Thomas: The interrelationships of birthweight, inflam-mation and body composition in healthy adults

Dr. Leib Stefanie: Relationships of iron metabolism with insulin resistance and glucose levels in young and healthy adults

Dr. Ruperti Repilado Javier: Relationship of N-Terminal fragment of Pro-B-Type Natriuretic Peptide and copeptin with erythrocy-tes-related parameters: A population-based study

Dr. Tabord Alexandra: Die neuen oralen Antikoagulantien zur SchlaganfallprŠvention bei Patienten mit Vorhofflimmern in der Schweiz - Eine Bestandsaufnahme

Dr. Metin Fatih: "Relationships of electrocardiographic parame-ters with ambulatory hypertension in young and healthy adults"

Dr. Aeschbacher Stefanie, PhD: "Lifestyle and heart rate variabi-lity in the general population"

Forschungspreise

Dr. Raphael Twerenbold: "Otto Hess Research Award"der Schweizerischen Gesellschaft fŸr Kardiologie

Dr. Jasper Boeddinghaus: "Otto Hess Research Award"der Schweizerischen Gesellschaft fŸr Kardiologie

Dr. Jasper Boeddinghaus: GREAT Meeting, Presentation Award

Dr. Patrick Badertscher: GREAT Meeting, Presentation Award

Dr. Krisai Philipp; Dr. Stefanie Aeschbacher: Pfizer Forschungs-preis 2016

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Kontakt

Kardiologie Basel

ChefarztProf. Dr. med. Stefan Osswald

AnschriftKardiologie BaselUniversitŠtsspital BaselPetersgraben 4CH - 4031 Baselunispital-basel.ch/kardiologie

Allgemeine AuskŸnfteTel +41 61 265 44 44, Fax +41 61 265 45 98Email: kardiologie@usb.ch

Anmeldung ambulante und stationŠre Patienten Tel. +41 61 265 44 45, Fax +41 61 265 55 75Email: anmeldung.kardiologie@usb.ch

Anmeldung kardiale RehabilitationTel. +41 61 328 65 27, Fax +41 61 265 55 03Email: karamba@usb.ch

Dienstarzt KardiologieTel. + 41 61 556 58 00

12 Kontakt

Herzchirurgie Basel

ChefarztProf. Dr. med. Friedrich Eckstein

AnschriftHerzchirurgie BaselUniversitŠtsspital BaselSpitalstrasse 21CH - 4031 Baselunispital-basel.ch/herzchirurgie

ChefarztsekretariatJolanda Giess Tel. +41 61 265 71 45, Fax +41 61 265 73 24Email: jolanda.giess@usb.ch

AnmeldungStationŠre Patienten Tel. + 41 61 265 71 45Ambulante Patienten Tel. + 41 61 265 71 45Aortensprechstunde Tel. + 41 61 265 71 46

Dienstarzt HerzchirurgieTel. + 41 61 556 58 58

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Impressum

Herausgeber: Herzzentrum Basel; Redaktion: Christoph Kaiser (Leitung), Stefan Osswald, Friedrich Eckstein, Christian MŸller, Florian RŸter, Markus Riesterer, Arton Jusaj, Ursula Vogt

Fotos: Markus Riesterer, Fabian Fiechter, Foto & Print Center USB, Christian Jaeggi, Patrick Sayer (Foto S. 55)

Konzeption: Markus Riesterer; Gestaltung: strawberry design; Druck: strawberry events; Auflage: 2'000 Ex.

Diese Publikation, einschliesslich all ihrer Texte, ist urheberrechtlich geschŸtzt. Jede Verwendung ausserhalb der engen Grenzen des Urheberrechts ist ohne Zustimmung des Herzzentrums und der beteiligten Institutionen unzulŠssig und strafbar. Dies gilt insbesondere fŸr VervielfŠltigungen, †bersetzungen, Mikroverfilmungen, sowie fŸr die Einspeicherung und Verarbeitung in elektronischen Systemen.

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unispital-basel.ch/kardiologie I unispital-basel.ch/herzchirurgie